Jie Han

发表

Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors.

Z. Chen, Hualiang Jiang, M. Zheng, 2020, Journal of medicinal chemistry.

Discovery of High-Affinity Inhibitors of the BPTF Bromodomain.

Kaixian Chen, Hualiang Jiang, Bo Li, 2021, Journal of medicinal chemistry.

Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening.

Kaixian Chen, Hualiang Jiang, C. Luo, 2019, Bioorganic chemistry.

The p300 Inhibitor A-485 Exerts Antitumor Activity in Growth Hormone Pituitary Adenoma

H. Ding, Haixia Cheng, Zhiyu Li, 2022, The Journal of clinical endocrinology and metabolism.

BRD4 as a therapeutic target for nonfunctioning and growth hormone pituitary adenoma

C. Luo, F. Ye, H. Ding, 2020, Neuro-oncology.

Development and Characterization of a Fluorescent Probe for GLS1 and the Application for High-Throughput Screening of Allosteric Inhibitors.

C. Luo, H. Ding, Xi Xu, 2019, Journal of medicinal chemistry.

Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening.

Hualiang Jiang, Wencong Lu, C. Luo, 2018, European journal of medicinal chemistry.

Design, Synthesis and Biological Evaluation of New Carbohydrate-Based Coumarin Derivatives as Selective Carbonic Anhydrase IX Inhibitors via “Click” Reaction

Yitong Wang, Jie Han, Hao Jia, 2022, Molecules.

Receptor-Interacting Protein Kinase 3 Inhibition Relieves Mechanical Allodynia and Suppresses NLRP3 Inflammasome and NF-κB in a Rat Model of Spinal Cord Injury

Jie Han, T. Sun, S. Xue, 2022, Frontiers in Molecular Neuroscience.

P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib

H. Ding, Shijie Chen, Yuanyuan Zhang, 2021, Acta Pharmacologica Sinica.

High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases

Kaixian Chen, Hualiang Jiang, C. Luo, 2021, Nucleic acids research.

Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening.

Kaixian Chen, Hualiang Jiang, C. Luo, 2020, Bioorganic chemistry.

Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay

Hao Jiang, C. Luo, H. Ding, 2018, Acta Pharmacologica Sinica.

P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib

C. Luo, H. Ding, Shijie Chen, 2021, Acta Pharmacologica Sinica.

Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors.

Z. Chen, Kaixian Chen, Hualiang Jiang, 2018, Bioorganic & medicinal chemistry.

The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening.

Kaixian Chen, C. Luo, F. Ye, 2019, Bioorganic & medicinal chemistry letters.

Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay

Hao Jiang, C. Luo, H. Ding, 2018, Acta Pharmacologica Sinica.

Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors.

C. Luo, H. Ding, Rukang Zhang, 2020, Bioorganic & medicinal chemistry letters.