Eunsook Lee

发表

Genetic Dys-regulation of Astrocytic Glutamate Transporter EAAT2 and its Implications in Neurological Disorders and Manganese Toxicity

M. Aschner, P. Karki, Keisha Smith, 2014, Neurochemical Research.

GPR30 Regulates Glutamate Transporter GLT-1 Expression in Rat Primary Astrocytes*

Kyuwon Lee, M. Aschner, D. Son, 2012, The Journal of Biological Chemistry.

Astrocyte-derived growth factors and estrogen neuroprotection: Role of transforming growth factor-α in estrogen-induced upregulation of glutamate transporters in astrocytes

P. Karki, Keisha Smith, James Johnson, 2014, Molecular and Cellular Endocrinology.

Role of Astrocytes in Brain Function and Disease

Michael Aschner, M. Aschner, Eunsook Lee, 2011, Toxicologic pathology.

Valproate and sodium butyrate attenuate manganese‐decreased locomotor activity and astrocytic glutamate transporters expression in mice

M. Aschner, D. Son, James Johnson, 2017, Neurotoxicology.

Yin Yang 1 Is a Repressor of Glutamate Transporter Eaat2, and It Mediates Manganese-induced Decrease of Eaat2 Expression in Astrocytes Impairment of Astrocytic Glutamate Transporter (glt-1; Eaat2) Function Is Associated with Multiple Neurodegenerative Dis- Eases, including Parkinson's Disease (pd) a

Kyuwon Lee, M. Aschner, P. Karki, 2022 .

Trace metals and animal health: Interplay of the gut microbiota with iron, manganese, zinc, and copper

D. Kang, Eunsook Lee, Eunsook Y. Lee, 2021, Animal nutrition.

Neurotoxicity mechanisms of manganese in the central nervous system.

M. Aschner, Eunsook Lee, Eunsook Y. Lee, 2021, Advances in neurotoxicology.

Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways

M. Aschner, P. Karki, D. Son, 2017, Molecular Neurobiology.

Estrogen Attenuates Manganese-Induced Glutamate Transporter Impairment in Rat Primary Astrocytes

M. Aschner, Eunsook Lee, J. Rocha, 2012, Neurotoxicity Research.

Transcriptional Regulation of Human Transforming Growth Factor-α in Astrocytes

M. Aschner, P. Karki, D. Son, 2016, Molecular Neurobiology.

The role of posttranslational modifications of α-synuclein and LRRK2 in Parkinson's disease: Potential contributions of environmental factors.

M. Aschner, Eunsook Lee, Eunsook Y. Lee, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity

M. Aschner, K. Soliman, D. Son, 2021, The Journal of biological chemistry.

Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.

M. Aschner, D. Milatović, Eunsook Lee, 2011, Neurotoxicology.

LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia

M. Aschner, D. Son, Eunsook Lee, 2019, PloS one.

Manganese Control of Glutamate Transporters' Gene Expression.

M. Aschner, P. Karki, James Johnson, 2017, Advances in neurobiology.

Transforming growth factor‐α mediates estrogen‐induced upregulation of glutamate transporter GLT‐1 in rat primary astrocytes

M. Aschner, D. Son, Eunsook Lee, 2012, Glia.

Deletion of RE1‐silencing transcription factor in striatal astrocytes exacerbates manganese‐induced neurotoxicity in mice

M. Aschner, D. Son, Eunsook Lee, 2022, Glia.

Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitigates manganese-induced dopaminergic neurotoxicity

M. Aschner, J. Bornhorst, D. Son, 2020, The Journal of Biological Chemistry.

Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity

M. Aschner, P. Karki, Keisha Smith, 2015, Neurochemistry International.

Mechanism of Mn(II)‐mediated dysregulation of glutamine–glutamate cycle: focus on glutamate turnover

M. Aschner, Eunsook Lee, M. Sidoryk-Węgrzynowicz, 2012, Journal of neurochemistry.

Role of Astrocytes in Manganese Neurotoxicity Revisited

M. Aschner, F. Soares, Eunsook Lee, 2019, Neurochemical Research.

The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics

M. Aschner, Eunsook Lee, Eunsook Y. Lee, 2019, Neuropharmacology.

Mechanism of raloxifene‐induced upregulation of glutamate transporters in rat primary astrocytes

P. Karki, D. Son, Eunsook Lee, 2014, Glia.

Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-κB and Yin Yang 1 (YY1)*

M. Aschner, P. Karki, D. Son, 2015, The Journal of Biological Chemistry.

Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes.

M. Aschner, D. Son, Eunsook Lee, 2021, Toxicology letters.

Astrocytic Yin Yang 1 is critical for murine brain development and protection against apoptosis, oxidative stress, and inflammation

M. Aschner, D. Son, Eunsook Lee, 2022, Glia.

cAMP Response Element-binding Protein (CREB) and Nuclear Factor κB Mediate the Tamoxifen-induced Up-regulation of Glutamate Transporter 1 (GLT-1) in Rat Astrocytes*

Kyuwon Lee, M. Aschner, P. Karki, 2013, The Journal of Biological Chemistry.

Mechanism of tamoxifen-induced GLT-1 expression 1 CREB and NF-Mediate the Tamoxifen-induced Upregulation of GLT-1 in Rat Astrocytes

Kyuwon Lee, M. Aschner, P. Karki, 2013 .

Molecular Targets of Manganese-Induced Neurotoxicity: A Five-Year Update

M. Aschner, A. Tsatsakis, S. Notova, 2021, International journal of molecular sciences.

Manganese disrupts astrocyte glutamine transporter expression and function

M. Aschner, Eunsook Lee, J. Albrecht, 2009, Journal of neurochemistry.