L. Meuse

发表

Extrachromosomal Recombinant Adeno-Associated Virus Vector Genomes Are Primarily Responsible for Stable Liver Transduction In Vivo

Theresa A. Storm, M. Kay, H. Nakai, 2001, Journal of Virology.

rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice

James M. Allen, J. Chamberlain, C. Murry, 2006, Nature Medicine.

Gene expression: RNA interference in adult mice

Douglas S. Conklin, Gregory J. Hannon, Anton P. McCaffrey, 2002, Nature.

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

M. Kay, J. Mikkelsen, S. Yant, 2002, Nature Biotechnology.

Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice.

Theresa A. Storm, M. Kay, M. Grompe, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo

M. Kay, Z. Chen, Cheng-Yi He, 2004, Gene Therapy.

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

A. Gown, M. Kay, G. Patijn, 1997, Nature Genetics.

Constitutive expression of murine CTLA4Ig from a recombinant adenovirus vector results in prolonged transgene expression

L. Meuse, D. Schowalter, D. Schowalter, 1997, Gene Therapy.

Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy.

Theresa A. Storm, M. Kay, D. Grimm, 2003, Blood.

Systemic delivery of genes to striated muscles using adeno-associated viral vectors

James M. Allen, Daniel G. Miller, D. Russell, 2004, Nature Medicine.

Long–term hepatic adenovirus–mediated gene expression in mice following CTLA4Ig administration

A. Gown, P. Linsley, M. Kay, 1995, Nature Genetics.

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

M. Kay, D. Bellinger, T. Nichols, 1999, Nature Medicine.

The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors

M. Kay, Cheng-Yi He, A. Lieber, 1997, Journal of virology.

Inclusion of the hepatic locus control region, an intron, and untranslated region increases and stabilizes hepatic factor IX gene expression in vivo but not in vitro.

M. Kay, G. Patijn, C. Miao, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Sustained survival of human hepatocytes in mice: A model for in vivo infection with human hepatitis B and hepatitis delta viruses

M. Kay, J. Glenn, H. Greenberg, 2000, Nature Medicine.

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.

A. Gown, P. Linsley, M. Kay, 1997, Proceedings of the National Academy of Sciences of the United States of America.

cMet activation allows persistent engraftment of ectopically transplanted xenogenic human hepatocytes in mice.

M. Kay, R. Schwall, K. Ohashi, 2001, Transplantation proceedings.

Adenovirus-mediated hepatic gene transfer in mice: comparison of intravascular and biliary administration.

M. Kay, G. Patijn, A. Lieber, 1996, Human gene therapy.

Epstein–Barr Virus/Human Vector Provides High-Level, Long-Term Expression of α1-Antitrypsin in Mice

M. Kay, M. Calos, L. Meuse, 2001 .

Optimization of cis-acting elements for gene expression from nonviral vectors in vivo.

M. Kay, Hui Xu, A. Ehrhardt, 2003, Human gene therapy.

A potent and specific morpholino antisense inhibitor of hepatitis C translation in mice

Anton P. McCaffrey, M. Kay, C. Contag, 2003, Hepatology.

In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus.

Ping Liu, M. Kay, J. Glenn, 2003, The Journal of clinical investigation.

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

M. Kay, Z. Izsvák, S. Yant, 2000, Nature Genetics.

The role of EBV and genomic sequences in gene expression from extrachromosomal gene therapy vectors in mouse liver Research

M. Kay, M. Calos, L. Meuse, 2004 .

Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo.

M. Kay, N. Fausto, A. Lieber, 1995, Proceedings of the National Academy of Sciences of the United States of America.

High-efficiency retrovirus-mediated gene transfer into the livers of mice.

M. Kay, G. Patijn, A. Lieber, 1998, Human gene therapy.

Epstein‐Barr Virus Vectors Provide Prolonged Robust Factor IX Expression in Mice

M. Kay, M. Calos, L. Meuse, 2003, Biotechnology progress.

A highly functional mini-dystrophin/GFP fusion gene for cell and gene therapy studies of Duchenne muscular dystrophy.

J. Faulkner, J. Chamberlain, M. Reyes, 2006, Human molecular genetics.

Determinants of hepatitis C translational initiation in vitro, in cultured cells and mice.

Anton P. McCaffrey, M. Kay, P. Sarnow, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver.

M. Kay, Z. Chen, Cheng-Yi He, 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

Inhibition of NF-κB Activation in Combination with Bcl-2 Expression Allows for Persistence of First-Generation Adenovirus Vectors in the Mouse Liver

M. Kay, A. Lieber, L. Meuse, 1998, Journal of Virology.

Design of tissue-specific regulatory cassettes for high-level rAAV-mediated expression in skeletal and cardiac muscle.

J. Chamberlain, L. Meuse, P. Gregorevic, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Helper-independent Sleeping Beauty Transposon–transposase Vectors for Efficient Nonviral Gene Delivery and Persistent Gene Expression in Vivo

M. Kay, J. Mikkelsen, Hui Xu, 2022 .

Site-specific genomic integration produces therapeutic Factor IX levels in mice

Eric C. Olivares, M. Kay, E. Olivares, 2002, Nature Biotechnology.

Epstein-Barr virus/human vector provides high-level, long-term expression of alpha1-antitrypsin in mice.

M. Kay, M. Calos, L. Meuse, 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

Free DNA ends are essential for concatemerization of synthetic double-stranded adeno-associated virus vector genomes transfected into mouse hepatocytes in vivo.

M. Kay, H. Nakai, S. Fuess, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.

A. Gown, P. Linsley, M. Kay, 1997, Proceedings of the National Academy of Sciences of the United States of America.