M. Pausch

发表

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

B. Roth, B. Armbruster, Xiang Li, 2007, Proceedings of the National Academy of Sciences.

Characterization of Gpr101 expression and G-protein coupling selectivity

Janet E. Paulsen, B. Bates, M. Pausch, 2006, Brain Research.

d-Amino Acid Oxidase Activity Is Inhibited by an Interaction with Bassoon Protein at the Presynaptic Active Zone

N. Brandon, E. Gundelfinger, P. Chanda, 2011, The Journal of Biological Chemistry.

A linear hexapeptide somatostatin antagonist blocks somatostatin activity in vitro and influences growth hormone release in rats.

R. Houghten, D. Carmignac, M. Pausch, 1998, Molecular Pharmacology.

Development of a Yeast Bioassay to Characterize G Protein-coupled Receptor Kinases

J. Benovic, M. Pausch, B. Noble, 2003, Journal of Biological Chemistry.

Pharmacological characterization of the rat A2a adenosine receptor functionally coupled to the yeast pheromone response pathway.

M. Pausch, J. Strnad, J. Hadcock, 1996, Molecular pharmacology.

Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development properties.

J. Renger, P. Coleman, A. Gotter, 2015, Bioorganic & medicinal chemistry letters.

Investigation of growth hormone releasing hormone receptor structure and activity using yeast expression technologies.

B. Ozenberger, M. Pausch, K. Young, 1997, Journal of receptor and signal transduction research.

Identification and characterization of novel somatostatin antagonists.

M. Pausch, J. Strnad, J. Hadcock, 1996, Molecular pharmacology.

Single Amino Acid Substitutions and Deletions That Alter the G Protein Coupling Properties of the V2 Vasopressin Receptor Identified in Yeast by Receptor Random Mutagenesis*

C. S. Gal, J. Wess, E. Kostenis, 2001, The Journal of Biological Chemistry.

Molecular Genetic Screen Design for Agricultural and Pharmaceutical Product Discovery

S. Silverman, D. Kirsch, M. Pausch, 2001 .

Yeast DNA primase and DNA polymerase activities. An analysis of RNA priming and its coupling to DNA synthesis.

C. Trainor, G. Williams, H. Singh, 1986, The Journal of biological chemistry.

Identification of potent inhibitors of the sortilin-progranulin interaction.

Gregory T O'Donnell, P. Coleman, M. Ziebell, 2020, Bioorganic & medicinal chemistry letters.

Functional expression of M1, M3 and M5 muscarinic acetylcholine receptors in yeast

J. Wess, E. Kostenis, F. Hamdan, 2001, Journal of neurochemistry.

MrgD Activation Inhibits KCNQ/M-Currents and Contributes to Enhanced Neuronal Excitability

Seena K. Ajit, M. Pausch, E. Kaftan, 2007, The Journal of Neuroscience.

Sequence and function of the two P domain potassium channels: implications of an emerging superfamily

M. Pausch, N. Ilan, S. Goldstein, 1997, Journal of Molecular Medicine.

The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function

A. Hayashi‐Takagi, Zhen Yan, R. Weinberg, 2011, Molecular Psychiatry.

ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae.

S. Goldstein, M. Pausch, L. A. Price, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway

B. Ozenberger, M. Pausch, J. Hadcock, 1995, Molecular and cellular biology.

Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D2 partial agonists for the potential treatment of schizophrenia.

K. Marquis, S. Grauer, J. Brennan, 2009, Bioorganic & medicinal chemistry letters.

Feedback Phosphorylation of an RGS Protein by MAP Kinase in Yeast*

R. Aebersold, H. Dohlman, M. Pausch, 1999, The Journal of Biological Chemistry.

Functional expression of human and mouse P2Y12 receptors in Saccharomyces cerevisiae.

Janet E. Paulsen, S. Kwak, B. Bates, 2004, Biochemical and biophysical research communications.

G-protein-coupled receptors in Saccharomyces cerevisiae: high-throughput screening assays for drug discovery.

M. Pausch, M H Pausch, Mark Henry Pausch, 1997, Trends in biotechnology.

Multiple Ca2+/calmodulin‐dependent protein kinase genes in a unicellular eukaryote.

J. Thorner, A. Admon, M. Pausch, 1991, The EMBO journal.

Title: Predicting Gpcr -g Protein Coupling Using Hidden Markov Models

K. Gulukota, M. Pausch, Youping Huang, 2004 .

Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78.

Janet E. Paulsen, B. Bates, M. Pausch, 2007, Biochimica et biophysica acta.

ADX47273 [S-(4-Fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities

F. Liu, M. Day, T. Comery, 2008, Journal of Pharmacology and Experimental Therapeutics.

Effects of alpha2-adrenoceptor antagonists on metabolic processes of swine: I. Effects on nonesterified fatty acid and plasma urea nitrogen concentrations in jugularly catheterized pigs.

M. Pausch, D. Search, J. Ingling, 1998, Journal of animal science.

N-terminal domain of Gpa1 (G protein alpha) subunit) is sufficient for plasma membrane targeting in yeast Saccharomyces cerevisiae.

H. Dohlman, M. Pausch, K. M. Gillen, 1998, Journal of cell science.

The orphan GPCR, GPR88, modulates function of the striatal dopamine system: A possible therapeutic target for psychiatric disorders?

K. Marquis, S. Grauer, Radka Graf, 2009, Molecular and Cellular Neuroscience.

Pharmacological comparison of muscarinic ligands: historical versus more recent muscarinic M1-preferring receptor agonists.

Tim Lock, Angela Kramer, K. Marquis, 2009, European journal of pharmacology.

WS-50030 [7-{4-[3-(1H-inden-3-yl)propyl]piperazin-1-yl}-1,3-benzoxazol-2(3H)-one]: A Novel Dopamine D2 Receptor Partial Agonist/Serotonin Reuptake Inhibitor with Preclinical Antipsychotic-Like and Antidepressant-Like Activity

K. Marquis, S. Grauer, J. Brennan, 2010, Journal of Pharmacology and Experimental Therapeutics.

Predicting GPCR-G-protein coupling using hidden Markov models

Kamalakar Gulukota, Kodangattil R. Sreekumar, You-Ping Huang, 2004, Bioinform..

Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist.

K. Marquis, J. Brennan, G. Stack, 2006, European Journal of Pharmacology.

Development of an improved IP(1) assay for the characterization of 5-HT(2C) receptor ligands.

R. Peri, M. Pausch, S. Nawoschik, 2010, Assay and drug development technologies.

Development of a FLIPR Assay for the Simultaneous Identification of MrgD Agonists and Antagonists from a Single Screen

Seena K. Ajit, M. Pausch, E. Kaftan, 2010, Journal of biomedicine & biotechnology.

The orphan GPCR, GPR88, modulates function of the striatal dopamine system: A possible therapeutic target for psychiatric disorders?

K. Marquis, S. Grauer, Radka Graf, 2009, Molecular and Cellular Neuroscience.

The identification of neurotensin NTS1 receptor partial agonists through a ligand-based virtual screening approach.

M. Pausch, M. Popiolek, Yi-Ran Fan, 2008, Bioorganic & medicinal chemistry letters.