J. Jankowsky

发表

Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

D. Borchelt, T. Golde, P. Cruz, 2013, PloS one.

NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease

G. Taglialatela, Hui Zheng, Hui-Chen Lu, 2015, Neuron.

Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

D. Borchelt, A. Savonenko, S. Younkin, 2005, The Journal of Neuroscience.

Strain Background Influences Neurotoxicity and Behavioral Abnormalities in Mice Expressing the Tetracycline Transactivator

Michael J. Yetman, Christie M. Buchovecky, M. Justice, 2012, The Journal of Neuroscience.

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

D. Borchelt, N. Copeland, N. Jenkins, 2001, Biomolecular engineering.

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Nancy A. Jenkins, D. Borchelt, 2004 .

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.

D. Borchelt, S. Younkin, L. Younkin, 2004, Human molecular genetics.

Intracerebroventricular viral injection of the neonatal mouse brain for persistent and widespread neuronal transduction.

Stacy D. Grunke, T. Golde, Y. Levites, 2014, Journal of visualized experiments : JoVE.

Gene therapy using Aβ variants for amyloid reduction.

N. L. Young, J. Jankowsky, Kyung-Won Park, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex

Michael J. Yetman, T. Leergaard, J. Bjaalie, 2015, Brain Structure and Function.

Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice.

D. Borchelt, D. Price, P. Wong, 2001, Human molecular genetics.

Neuronal overexpression of human VAPB slows motor impairment and neuromuscular denervation in a mouse model of ALS.

W. Yoon, Ji-Yoen Kim, J. Jankowsky, 2016, Human molecular genetics.

Widespread Neuronal Transduction of the Rodent CNS via Neonatal Viral Injection.

Stacy D. Grunke, Ji-Yoen Kim, J. Jankowsky, 2016, Methods in molecular biology.

1 Activity disruption causes degeneration of entorhinal neurons in a mouse model of Alzheimer ’ s circuit dysfunction 2 3

Stacy D. Grunke, J. Jankowsky, Kyung-Won Park, 2022 .

Activity disruption causes degeneration of entorhinal neurons in a mouse model of Alzheimer’s circuit dysfunction

Stacy D. Grunke, J. Jankowsky, Ming-hua Li, 2022, eLife.

Practical considerations for choosing a mouse model of Alzheimer’s disease

Hui Zheng, J. Jankowsky, 2017, Molecular Neurodegeneration.

Genetic Suppression of Transgenic APP Rescues Hypersynchronous Network Activity in a Mouse Model of Alzeimer's Disease

T. Golde, J. Cirrito, J. Noebels, 2014, The Journal of Neuroscience.

Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

Hui Zheng, J. Jankowsky, Hong Lian, 2016, The Journal of Neuroscience.

Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability

Rong Zhao, Daoyun Ji, Alexander Lam, 2016, Cell reports.

APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1

D. Borchelt, N. Jenkins, V. Gonzales, 2004, Neurobiology of Aging.

Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult

J. Jankowsky, P. Das, H. A. Born, 2012, Molecular Neurodegeneration.

Open access, freely available online PLoS MEDICINE Persistent Amyloidosis following Suppression of Ab Production in a Transgenic Model of Alzheimer Disease

H. Lester, D. Borchelt, A. Savonenko, 2022 .

Combination of Aβ Suppression and Innate Immune Activation in the Brain Significantly Attenuates Amyloid Plaque Deposition.

Paramita Chakrabarty, J. Jankowsky, P. Das, 2017, The American journal of pathology.

Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.

Nicholas E. Propson, Zhandong Liu, J. Trojanowski, 2020, The Journal of clinical investigation.

Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse

R. Paylor, J. Jankowsky, P. Paganetti, 2012, Behavioural Brain Research.

Differential Regulation of Cytokine Expression Following Pilocarpine-Induced Seizure

P. Patterson, J. Jankowsky, 1999, Experimental Neurology.

The role of cytokines and growth factors in seizures and their sequelae

P. Patterson, J. Jankowsky, 2001, Progress in Neurobiology.

Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction

Michael J. Yetman, J. Jankowsky, S. Fowler, 2016, PloS one.

Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo

S. Smirnakis, T. Golde, Y. Levites, 2013, The European journal of neuroscience.

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

Michael J. Yetman, D. Brat, K. Loeb, 2015, Nature.

Genetic Modulation of Soluble Aβ Rescues Cognitive and Synaptic Impairment in a Mouse Model of Alzheimer's Disease

J. Cirrito, S. Lesné, J. Jankowsky, 2014, The Journal of Neuroscience.

Cytokine and Growth Factor Involvement in Long-Term Potentiation

P. Patterson, J. Jankowsky, 1999, Molecular and Cellular Neuroscience.

Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

Michael J. Yetman, D. Brat, K. Loeb, 2015, Nature.

Environmental Enrichment Exacerbates Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease

D. Borchelt, V. Gonzales, J. Jankowsky, 2003, Journal of neuropathology and experimental neurology.

Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease.

Stacy D. Grunke, H. Zoghbi, J. Botas, 2019, Human molecular genetics.

Alzheimer's-Type Amyloidosis in Transgenic Mice Impairs Survival of Newborn Neurons Derived from Adult Hippocampal Neurogenesis

C. Rampon, D. Borchelt, J. Jankowsky, 2007, The Journal of Neuroscience.

Temporal and spatially controlled APP transgene expression using Cre-dependent alleles

J. Jankowsky, Jonathan C. Bean, Kyung-Won Park, 2022, Disease models & mechanisms.

Transgenic mouse models of neurodegenerative disease: Opportunities for therapeutic development

Alena Savonenko, D. Borchelt, A. Savonenko, 2002, Current neurology and neuroscience reports.

Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration.

K. Zahs, K. Ashe, J. Cleary, 2015, Cell reports.

Wild-Type Neural Progenitors Divide and Differentiate Normally in an Amyloid-Rich Environment

Michael J. Yetman, J. Jankowsky, 2013, The Journal of Neuroscience.

Robust Amyloid Clearance in a Mouse Model of Alzheimer's Disease Provides Novel Insights into the Mechanism of Amyloid-β Immunotherapy

T. Golde, R. Switzer, J. Jankowsky, 2011, The Journal of Neuroscience.

Impairments in experience‐dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease

D. Ji, J. Jankowsky, Angie C A Chiang, 2014, Hippocampus.

Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice

S. Hilsenbeck, J. Cirrito, J. Jankowsky, 2018, The Journal of experimental medicine.

Amyloid-β plaques disrupt axon initial segments

J. Jankowsky, M. A. Marin, M. Rasband, 2016, Experimental Neurology.

Cytokine responses to LTP induction in the rat hippocampus: a comparison of in vitro and in vivo techniques.

B. Derrick, P. Patterson, J. Jankowsky, 2000, Learning & memory.

Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis.

J. Troncoso, S. Lesné, J. Jankowsky, 2017, The American journal of pathology.

Quaternary Structure Defi nes a Large Class of Amyloid-b Oligomers Neutralized by Sequestration Graphical

K. Zahs, K. Ashe, J. Cleary, 2015 .

Remote sites of structural atrophy predict later amyloid formation in a mouse model of Alzheimer's disease

G. Allan Johnson, Alexandra Badea, Joanna L. Jankowsky, 2010, NeuroImage.

Specificity and efficiency of reporter expression in adult neural progenitors vary substantially among nestin‐CreERT2 lines

Michael J. Yetman, Yuqing Chen, J. Jankowsky, 2014, The Journal of comparative neurology.

TMEM106B regulates microglial proliferation and survival in response to demyelination

W. Seeley, Tuancheng Feng, Fenghua Hu, 2023, Science advances.

Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice*

H. Lester, D. Borchelt, S. Younkin, 2007, Journal of Biological Chemistry.

Acute silencing uncovers multiple forms of activity-dependent neuronal survival in the mature entorhinal cortex

Stacy D. Grunke, A. Singh, J. Jankowsky, 2021, bioRxiv.

Brain-wide distribution of reporter expression in five transgenic tetracycline-transactivator mouse lines

Trygve B. Leergaard, Jan G. Bjaalie, Maja A. Puchades, 2019, Scientific data.

Brain-wide distribution of reporter expression in five transgenic tetracycline-transactivator mouse lines

Maja A. Puchades, Michael J. Yetman, Martyna M. Checinska, 2019, Scientific Data.

GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET

H. Lester, P. Imoukhuede, M. Quick, 2009, The Journal of general physiology.

Alpha 4-containing neuronal nicotinic receptors modulate appetitive learning

Lori, Steven A. Spronk, E. Slimko, 2004 .

Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex

Michael J. Yetman, T. Leergaard, J. Bjaalie, 2016, Brain Structure and Function.

Robust amyloid clearance in a mouse model of AD provides novel insights into the mechanism of A β immunotherapy

T. Golde, R. Switzer, J. Jankowsky, 2011 .

TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy

I. Al-Ramahi, J. Jankowsky, G. Edwards, 2023, bioRxiv.

Cerebral Vascular Leak in a Mouse Model of Amyloid Neuropathology

A. Annapragada, J. Jankowsky, S. Fowler, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Practical considerations for choosing a mouse model of Alzheimer’s disease

Hui Zheng, J. Jankowsky, 2017, Molecular Neurodegeneration.

Brain-wide distribution of reporter expression in five transgenic tetracycline-transactivator mouse lines

Maja A. Puchades, Michael J. Yetman, Martyna M. Checinska, 2019, Scientific Data.

Combination of Aβ Suppression and Innate Immune Activation in the Brain Significantly Attenuates Amyloid Plaque Deposition.

Paramita Chakrabarty, J. Jankowsky, Christophe Verbeeck, 2017, The American journal of pathology.

Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration.

K. Zahs, K. Ashe, J. Cleary, 2015, Cell reports.

Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of AD

J. Cirrito, S. Lesné, J. Jankowsky, 2013, Molecular Neurodegeneration.

Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of AD

J. Cirrito, S. Lesné, J. Jankowsky, 2013, Molecular Neurodegeneration.