I. Tickle

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Structure of pentameric human serum amyloid P component

T. Blundell, N. Srinivasan, J. Emsley, 1994, Nature.

The crystal structures of [Met5]enkephalin and a third form of [Leu5]enkephalin: observations of a novel pleated beta-sheet.

T. Blundell, D. Langs, G. D. Smith, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Statistical quality indicators for electron-density maps

Ian J. Tickle, I. Tickle, 2012, Acta crystallographica. Section D, Biological crystallography.

The relation of polypeptide hormone structure and flexibility to receptor binding: The relevance of X-ray studies on insulins, glucagon and human placental lactogen

T. L. Blundell, I. J. Tickle, T. Blundell, 1975, Molecular and Cellular Biochemistry.

Detection of secondary binding sites in proteins using fragment screening

Marcel L Verdonk, M. Verdonk, H. Jhoti, 2015, Proceedings of the National Academy of Sciences.

An improved method for intensity data collection with a computer‐controlled diffractometer

I. Tickle, 1975 .

Fragment screening using X-ray crystallography.

T. Davies, I. Tickle, Thomas G Davies, 2012, Topics in current chemistry.

X-ray analyses of aspartic proteinases. II. Three-dimensional structure of the hexagonal crystal form of porcine pepsin at 2.3 A resolution.

T. Blundell, J. Cooper, G. Taylor, 1990, Journal of molecular biology.

XModeScore: a novel method for accurate protonation/tautomer-state determination using quantum-mechanically driven macromolecular X-ray crystallographic refinement

Lance M. Westerhoff, I. Tickle, O. Borbulevych, 2016, Acta crystallographica. Section D, Structural biology.

Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding.

T. Blundell, V. Hruby, J. Pitts, 1988, Science.

The structures of crystalline complexes of human serum amyloid P component with its carbohydrate ligand, the cyclic pyruvate acetal of galactose.

S. Wood, M. Pepys, I. Tickle, 2002, Journal of molecular biology.

The relation of structure to storage and receptor binding of glucagon.

S. Wood, I. Tickle, T. Blundell, 1976, Metabolism: clinical and experimental.

Insulin polymorphism: some physical and biological properties of rat insulins.

T. Blundell, D. Steiner, S. Wood, 1978, Archives of biochemistry and biophysics.

Polypeptide hormone-receptor interactions: the structure and receptor binding of insulin and glucagon.

S. Wood, I. Tickle, S. Bedarkar, 1977, Ciba Foundation symposium.

Purification, crystallisation and preliminary X-ray studies on avian pancreatic polypeptide.

T. Blundell, J. Jenkins, J. Pitts, 1977, European journal of biochemistry.

Colour stereo space-filling representations of Ribonuclease- mononucleotide interactions

N. Borkakoti, D. Moss, I. Tickle, 1983 .

Crystallisation and preliminary crystallographic data of a porcine neurophysin I—Tyr‐Phe‐NH2 complex

T. Blundell, T. Blundell, J. Pitts, 1980, FEBS letters.

Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone

Jose Cosme, Clemens Vonrhein, C. Vonrhein, 2004, Science.

The crystal structures of three non-pancreatic human insulins

T. Blundell, J. Pitts, E. Dodson, 1983, Diabetologia.

The molecular structure and stability of the eye lens: x-ray analysis of gamma-crystallin II.

T. Blundell, D. Moss, G. Wistow, 1981, Nature.

Error estimates of protein structure coordinates and deviations from standard geometry by full-matrix refinement of gammaB- and betaB2-crystallin.

D S Moss, I J Tickle, R A Laskowski, 1998, Acta crystallographica. Section D, Biological crystallography.

MAD analyses of yeast 5-aminolaevulinate dehydratase: their use in structure determination and in defining the metal-binding sites.

J. Cooper, I. Tickle, M. Warren, 2000, Acta crystallographica. Section D, Biological crystallography.

Crystal Structure of the Marburg Virus VP35 Oligomerization Domain

G. Bricogne, E. Saphire, Sheng Li, 2016, Journal of Virology.

Crystal and molecular structure of stercuronium iodide ethanol solvate: A peripheral muscle relaxant

I. Tickle, R. Palmer, J. Husain, 1981 .

Fragment-based lead discovery using X-ray crystallography.

Christopher W Murray, Michael J Hartshorn, C. Murray, 2005, Journal of medicinal chemistry.

The conformation of deamino-oxytocin: X-ray analysis of the 'dry' and 'wet' forms.

T. Blundell, V. Hruby, J. Pitts, 1990, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

X-ray analyses of aspartic proteinases. The three-dimensional structure at 2.1 A resolution of endothiapepsin.

T. Blundell, J. Jenkins, L. Pearl, 1994, Journal of molecular biology.

Crystal structure of momordin, a type I Ribosome Inactivating Protein from the seeds of Momordica charantia

S. Wood, I. Tickle, J. Husain, 1994, FEBS letters.

Molecular complexes. Part XV. Crystal structure of the 1 : 1 molecular complex of pyrene and 1,2,4,5-tetracyanobenzene at 290 and 178 K

I. Tickle, C. Prout, J. Wright, 1973 .

Molecular complexes. Part XVI. Crystal structure of the 1 : 1 molecular complex of pyrene and 7,7,8,8-tetracyanoquinodimethane

I. Tickle, C. Prout, J. Wright, 1973 .

Molecular complexes. Part XXI. Crystal and molecular structure of pyrene–1,3,5-trinitrobenzene

I. Tickle, C. Prout, 1973 .

Molecular complexes. Part XXII. Crystal and molecular structure of the molecular complex of pyrene and chloranil

I. Tickle, K. Prout, 1973 .

I. Tickle, T. Bhardwaj, R. Palmer, 1982 .

A New Generation of Crystallographic Validation Tools for the Protein Data Bank

Randy J. Read, Paul D. Adams, Gerard J. Kleywegt, 2011, Structure.

The molecular structure and stability of the eye lens: X-ray analysis of γ-crystallin II

Graeme Wistow, Ian Tickle, Tom Blundell, 1981, Nature.

Homology among acid proteases: comparison of crystal structures at 3A resolution of acid proteases from Rhizopus chinensis and Endothia parasitica.

T. Blundell, J. Jenkins, D. Davies, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Refinement of the solution structure of the B DNA hexamer 5'd(C-G-T-A-C-G)2 on the basis of inter-proton distance data.

A. Gronenborn, G. Clore, D. Moss, 1985, Journal of molecular biology.

Crystal structure of human CDK4 in complex with a D-type cyclin

Rajiv Chopra, Jeff Yon, Christoph Lengauer, 2009, Proceedings of the National Academy of Sciences.

Conformational studies on the pancreatic polypeptide hormone family.

T. Blundell, D. Barlow, J. Pitts, 1984, European journal of biochemistry.

Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG).

S. Neidle, B. F. Li, I. Tickle, 1990, Proceedings of the National Academy of Sciences of the United States of America.

X-ray analysis of glucagon and its relationship to receptor binding

Ian J. Tickle, Tom Blundell, T. Blundell, 1975, Nature.

High-throughput protein crystallography and drug discovery.

Ian Tickle, Jeff Yon, Andrew Sharff, 2004, Chemical Society reviews.

PDB_REDO: automated re-refinement of X-ray structure models in the PDB

Vincent Breton, Gert Vriend, Christophe Combet, 2009, Journal of applied crystallography.

X-ray analysis (1. 4-A resolution) of avian pancreatic polypeptide: Small globular protein hormone.

T. Blundell, J. Pitts, C. Wu, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Receptor-binding region of insulin

T. Blundell, S. Gammeltoft, S. Wood, 1976, Nature.

Experimental determination of optimal root-mean-square deviations of macromolecular bond lengths and angles from their restrained ideal values.

I. Tickle, Ian J Tickle, 2007, Acta crystallographica. Section D, Biological crystallography.

The low resolution structure analysis of an acid proteinase from Endothia parasitica.

T. Blundell, J. Jenkins, I. Tickle, 1975, Journal of molecular biology.

Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP.

A. Sharff, H. Nar, J. Yon, 2007, Acta crystallographica. Section D, Biological crystallography.

Adaptation of plasminogen activator sequences to known protease structures

T. Blundell, J. Pitts, L. Flohé, 1983, FEBS letters.

X-Ray Analysis of Polypeptide Hormones at ≦1Å Resolution: Anisotropic Thermal Motion and Secondary Structure of Pancreatic Polypeptide and Deamino-Oxytocin

T. Blundell, J. Pitts, S. Wood, 1987 .

X-ray analyses of aspartic proteinases. IV. Structure and refinement at 2.2 A resolution of bovine chymosin.

T L Blundell, I J Tickle, T. Blundell, 1991, Journal of molecular biology.

Engineering of an intersubunit disulfide bridge in the iron-superoxide dismutase of Mycobacterium tuberculosis.

J. Cooper, K. Bunting, D. Young, 2002, Archives of biochemistry and biophysics.

X-ray analysis and circular dichroism of the acid protease from Endothia parasitica and chymosin.

T. Blundell, A. Wollmer, T. Sewell, 1977, Advances in experimental medicine and biology.

Engineering a change in metal-ion specificity of the iron-dependent superoxide dismutase from Mycobacterium tuberculosis-- X-ray structure analysis of site-directed mutants.

I J Tickle, J. Cooper, S. Wood, 1998, European journal of biochemistry.

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

J. Yon, T. Davies, P. Ward, 2014, PloS one.

X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase

J. Cooper, S. Wood, P. Thomas, 1997, Nature Structural Biology.

Two Structural Transitions in Membrane Pore Formation by Pneumolysin, the Pore-Forming Toxin of Streptococcus pneumoniae

H. Saibil, P. Andrew, J. Rossjohn, 1999, Cell.

Molecular complexes. Part XVIII. Crystal and molecular structure of acenaphthene–tetrachloro-p-benzoquinone molecular complex

I. Tickle, C. Prout, 1973 .

X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus.

T L Blundell, I J Tickle, T. Blundell, 1993, Journal of molecular biology.

Sensitivity of molecular docking to induced fit effects in influenza virus neuraminidase

Marcel L. Verdonk, Christopher W. Murray, Michael J. Hartshorn, 2002, J. Comput. Aided Mol. Des..

Advances in automated data analysis and processing within autoPROC, combined with improved characterisation, mitigation and visualisation of the anisotropy of diffraction limits using STARANISO

A. Sharff, G. Bricogne, C. Vonrhein, 2018, Acta Crystallographica Section A Foundations and Advances.

Conformational flexibility in a small globular hormone: X‐ray analysis of avian pancreatic polypeptide at 0.98‐Å resolution

T. Blundell, D. Moss, J. Pitts, 1983, Biopolymers.

Structural studies on avian pancreatic polypeptide [proceedings].

T. Blundell, J. Jenkins, J. Pitts, 1977, Biochemical Society transactions.

Molecular complexes. Part XIV. Crystal and molecular structure of the π*-electron-acceptor molecule 1,2,4,5-tetracyanobenzene

I. Tickle, C. Prout, 1973 .

Crystal structure of [Leu5]enkephalin.

T. Blundell, G. D. Smith, B. Morgan, 1979, Science.

Molecular complexes. Part XVII. Crystal and molecular structure of perylene–7,7,8,8-tetracyanoquinodimethane molecular complex

I. Tickle, C. Prout, 1973 .

Folded conformations. Part V. Crystal and molecular structure of ethyl N-methyl-N-(p-tolylsulphonylmethyl)carbamate at –160 °C

J. Engberts, I. Tickle, 1973 .

STRUCTURAL EVIDENCE FOR GENE DUPLICATION AND FUSION IN THE EVOLUTION OF PROTEINS

J. Jenkins, D. Moss, T. Sewell, 1981 .

Acetylcholine receptor site: a proposed model

I. Tickle, R. Palmer, J. Tickle, 1983 .

Fragment-Based Screening by X-ray Crystallography

Miles Stuart Congreve, I. J. Tickle, Valerio Berdini, 2007 .

Automated Protein–Ligand Crystallography for Structure‐Based Drug Design

Marcel L Verdonk, Michael J Hartshorn, Wijnand T M Mooij, 2006, ChemMedChem.

The structure of tetrazole steroid analogues. III. Structure of 4,6‐diaza‐A,B‐bishomocholest‐4a‐eno[4,3‐d][6,7‐d]bistetrazole (HS‐649), C27H42N8

I. Tickle, R. Palmer, K. Bhutani, 1983 .

The structure of tetrazole steroid analogues. II. The structure of 3,6‐diaza‐A,B‐bishomocholest‐4a‐eno[3,4‐d][6,7‐d]bistetrazole (HS‐650) monohydrate

I. Tickle, R. Palmer, K. Bhutani, 1982 .

X-ray analyses of peptide–inhibitor complexes define the structural basis of specificity for human and mouse renins

T. L. Blundell, V. Dhanaraj, H. P. C. Driessen, 1992, Nature.

Molecular replacement using known structural information.

I. Tickle, H. Driessen, 1996, Methods in molecular biology.

Structure of oligomeric beta B2-crystallin: an application of the T2 translation function to an asymmetric unit containing two dimers.

D. Moss, D. Mahadevan, I. Tickle, 1991, Acta Crystallographica Section B Structural Science.

GLUCAGON AND PANCREATIC HORMONE III: X-RAY ANALYSIS, CONFORMATION AND RECEPTOR BINDING

T. Blundell, J. Pitts, S. Wood, 1978 .

PDB_REDO: automated re-refinement of X-ray structure models in the PDB

G. Vriend, G. Deléage, H. Stockinger, 2009, Journal of applied crystallography.

STARANISO: use of a WebGL-based 3D interactive graphical display to represent and visualise data quality metrics for anisotropic macromolecular diffraction data

I. Tickle, 2019, Acta Crystallographica Section A Foundations and Advances.

Error Estimates of Protein Structure Coordinates and Deviations from Standard Geometry by Full-Matrix Refinement of γB- and βB2-Crystallin

David S. Moss, Roman A. Laskowski, Ian J. Tickle, 1998 .

Rfree and the rfree ratio. I. Derivation of expected values of cross-validation residuals used in macromolecular least-squares refinement.

D S Moss, I J Tickle, R A Laskowski, 1998, Acta crystallographica. Section D, Biological crystallography.

Structure of gallamine bromide iodide aqueous ethanol methanol solvate: simulation of an acetylcholine receptor site by computer graphics

I. Tickle, R. Palmer, J. Husain, 1985 .