Yongzhang Luo

发表

Contributions of Zn(II)‐binding to the structural stability of endostatin

Qing Han, Yan Fu, Hao Zhou, 2007, FEBS letters.

growth factor and nonmuscle myosin The angiogenesis function of nucleolin is mediated by vascular endothelial

Hubing Shi, Yongzhang Luo, Yujie Huang, 2012 .

The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin.

Hubing Shi, Haochen Zhou, Yongzhang Luo, 2006, Blood.

The Regulatory Mechanism of Extracellular Hsp90α on Matrix Metalloproteinase-2 Processing and Tumor Angiogenesis*

Hubing Shi, D. Feng, Yi Sun, 2010, The Journal of Biological Chemistry.

Overexpression of platelet-derived growth factor-BB increases tumor pericyte content via stromal-derived factor-1alpha/CXCR4 axis.

Hubing Shi, Xiaomin Song, Yan Fu, 2009, Cancer research.

The regulatory mechanism of a client kinase controlling its own release from Hsp90 chaperone machinery through phosphorylation

Yan Fu, Yongzhang Luo, Xiaofeng Wang, 2013, The Biochemical journal.

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1

Shuohua Chen, Yan Fu, Yongzhang Luo, 2019, Journal of Cell Science.

Genetically engineered endostatin-lidamycin fusion proteins effectively inhibit tumor growth and metastasis

Wenguo Jiang, S. Zhang, Y. Zhen, 2013, BMC Cancer.

The regulatory mechanism of Hsp90alpha secretion from endothelial cells and its role in angiogenesis during wound healing.

Yongzhang Luo, Xiaoming Song, 2010, Biochemical and biophysical research communications.

TP53 mutations upregulate RCP expression via Sp1/3 to drive lung cancer progression

Yan Fu, Yongzhang Luo, Caihong Wang, 2022, Oncogene.

Antigen Peptide Transporter 1 (TAP1) Promotes Resistance to MEK Inhibitors in Pancreatic Cancers

Yan Fu, Yongzhang Luo, Boya Li, 2022, International journal of molecular sciences.

Deficiency of Disulfide Bonds Facilitating Fibrillogenesis of Endostatin*

Huadong Tang, Hao Zhou, Yingbo He, 2006, Journal of Biological Chemistry.

Heat Shock Cognate 70 Regulates the Translocation and Angiogenic Function of Nucleolin

T. He, Yan Fu, Yongzhang Luo, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer1

Yan Fu, Yongzhang Luo, Yang Tian, 2019, Neoplasia.

The CXCL12–CXCR4 Chemokine Pathway: A Novel Axis Regulates Lymphangiogenesis

Yan Fu, Yongzhang Luo, Xiaoming Song, 2012, Clinical Cancer Research.

Soluble tissue factor has unique angiogenic activities that selectively promote migration and differentiation but not proliferation of endothelial cells.

Yingbo He, Yongzhang Luo, Xiaoming Song, 2008, Biochemical and biophysical research communications.

Alpha(E)C, the C-terminal extension of fibrinogen, has chaperone-like activity.

Huadong Tang, Yan Fu, Yongzhang Luo, 2009, Biochemistry.

Endostatin Prevents Dietary-Induced Obesity by Inhibiting Adipogenesis and Angiogenesis

Yan Fu, Yongzhang Luo, Xin-An Lu, 2015, Diabetes.

Thr90 phosphorylation of Hsp90α by protein kinase A regulates its chaperone machinery.

Yongzhang Luo, Xiaoming Song, Xiaofeng Wang, 2012, The Biochemical journal.

Fibrinogen facilitates the anti-tumor effect of nonnative endostatin.

F. Castellino, V. Ploplis, Huadong Tang, 2009, Biochemical and biophysical research communications.

Tumor-Associated Macrophages Promote Angiogenesis and Melanoma Growth via Adrenomedullin in a Paracrine and Autocrine Manner

Yongzhang Luo, Yujie Huang, Xiaoming Song, 2011, Clinical Cancer Research.

Tumor-associated macrophages promote angiogenesis and melanoma growth via adrenomedullin in both paracrine and autocrine manners

Yongzhang Luo, Yujie Huang, Xiaoming Song, 2011 .

Pharmacokinetics of PEGylated recombinant human endostatin in rhesus monkeys.

Yan Fu, Yongzhang Luo, Lihong Liu, 2019, Life sciences.

Quality, bioactivity study, and preclinical acute toxicity, safety pharmacology evaluation of PEGylated recombinant human endostatin (M2ES)

Yan Fu, Yongzhang Luo, Lihong Liu, 2018, Journal of biochemical and molecular toxicology.

A pre‐clinical safety study of PEGylated recombinant human endostatin (M2ES) in Sprague Dawley rats

Q. Peng, W. Qi, Yan Fu, 2018, Regulatory toxicology and pharmacology : RTP.

E-M, an Engineered Endostatin with High ATPase Activity, Inhibits the Recruitment and Alternative Activation of Macrophages in Non-small Cell Lung Cancer

Shan Wang, Yan Fu, Yongzhang Luo, 2017, Front. Pharmacol..

Endostatin sensitizes p53‐deficient non‐small‐cell lung cancer to genotoxic chemotherapy by targeting DNA‐dependent protein kinase catalytic subunit

Shan Wang, Yan Fu, Yongzhang Luo, 2017, The Journal of pathology.

Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog

Shan Wang, Yan Fu, Yongzhang Luo, 2016, Chinese journal of cancer.

Nuclear-translocated endostatin downregulates hypoxia inducible factor-1α activation through interfering with Zn(II) homeostasis.

T. He, Junzhi Wang, Yan Fu, 2015, Molecular medicine reports.

Pre-clinical toxicokinetics and safety study of M2ES, a PEGylated recombinant human endostatin, in rhesus monkeys.

Yan Fu, Yongzhang Luo, Xingchao Geng, 2014, Regulatory toxicology and pharmacology : RTP.

Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Yongzhang Luo, Xiaoming Song, W. Zhuo, 2011, Frontiers of medicine.

Sulfate stabilizes the folding intermediate more than the native structure of endostatin.

Qing Han, Yan Fu, Yingbo He, 2008, Archives of biochemistry and biophysics.

Title: Nucleolin is a Receptor that Mediates Antiangiogenic and Anti-tumor Activity of Endostatin Short title: Nucleolin is a Receptor for Endostatin

Hubing Shi, Yongzhang Luo, Yujie Huang, 2007 .

Detection and characterization of an acid-induced folding intermediate of endostatin.

Yongzhang Luo, Jing Huang, Guodong Chang, 2004, Biochemical and biophysical research communications.

Extracellular Heat Shock Protein-90 (eHsp90): Everything You Need to Know

Yongzhang Luo, Wei Li, D. Jay, 2022, Biomolecules.

Young and Undamaged rMSA Improves the Healthspan and Lifespan of Mice

Yan Fu, Yongzhang Luo, Boya Li, 2021, Biomolecules.

Arginine deiminase modulates endothelial tip cells via excessive synthesis of reactive oxygen species.

Haochen Zhou, Yongzhang Luo, Xiaoming Song, 2011, Biochemical Society transactions.

Endostatin Has ATPase Activity, Which Mediates Its Antiangiogenic and Antitumor Activities

P. Liu, Shan Wang, Yan Fu, 2015, Molecular Cancer Therapeutics.

Sequence-specific DNA Cleavage by Fe2+-mediated Fenton Reactions Has Possible Biological Implications*

S. Linn, Yongzhang Luo, P. Rai, 1999, The Journal of Biological Chemistry.

Oxidative Damage to DNA Constituents by Iron-mediated Fenton Reactions

S. Linn, Yongzhang Luo, W. Gassmann, 1996, The Journal of Biological Chemistry.

Fibrinogen has chaperone-like activity.

F. Castellino, V. Ploplis, Huadong Tang, 2009, Biochemical and biophysical research communications.

NFAT1 Mediates Placental Growth Factor-Induced Myelomonocytic Cell Recruitment via the Induction of TNF-α

Yan Fu, Yongzhang Luo, Hongchen Cai, 2010, The Journal of Immunology.

The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy

Hubing Shi, Yan Fu, Yongzhang Luo, 2009, Proceedings of the National Academy of Sciences.

PLCγ1–PKCγ Signaling‐Mediated Hsp90α Plasma Membrane Translocation Facilitates Tumor Metastasis

Yan Fu, Yongzhang Luo, Xiaoming Song, 2014, Traffic.

Biophysical and biological characterization of PEGylated recombinant human endostatin

Yan Fu, Yongzhang Luo, Lihong Liu, 2019, Clinical and experimental pharmacology & physiology.

Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E

Yan Fu, Yongzhang Luo, Boya Li, 2019, Journal of experimental & clinical cancer research : CR.

Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis.

Hubing Shi, Yongzhang Luo, Hongchen Cai, 2009, Cancer research.

Shuohua Chen, Yan Fu, Yongzhang Luo, 2021, bioRxiv.

Role of Bone Marrow-Derived Cells in Angiogenesis: Focus on Macrophages and Pericytes

Yongzhang Luo, Yanping Ding, Nan Song, 2012, Cancer Microenvironment.

Extracellular Hsp90α Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer

Shuohua Chen, Yan Fu, Yongzhang Luo, 2021, International journal of molecular sciences.

A novel pan‐cancer biomarker plasma heat shock protein 90alpha and its diagnosis determinants in clinic

Wei Liu, Hubing Shi, D. Cui, 2019, Cancer science.

High expression of small GTPase Rab3D promotes cancer progression and metastasis

Wei Liu, Yan Fu, Yongzhang Luo, 2015, Oncotarget.

Suppression of CCT3 Inhibits Tumor Progression by Impairing ATP Production and Cytoplasmic Translation in Lung Adenocarcinoma

Yan Fu, Yongzhang Luo, Boya Li, 2022, International journal of molecular sciences.

CXCR7 promotes melanoma tumorigenesis via Src kinase signaling

Yan Fu, Yongzhang Luo, Jie Liu, 2019, Cell Death & Disease.

MicroRNA‐542‐3p inhibits tumour angiogenesis by targeting Angiopoietin‐2

Yan Fu, Lifang Guo, Shan Wang, 2014, The Journal of pathology.

Endostatin inhibits tumour lymphangiogenesis and lymphatic metastasis via cell surface nucleolin on lymphangiogenic endothelial cells

C. Luo, Yan Fu, Yongzhang Luo, 2010, The Journal of pathology.

Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p.

Shan Wang, T. He, Yan Fu, 2015, Cancer letters.

The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells

T. He, Yan Fu, Yongzhang Luo, 2012, Angiogenesis.

Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice

Yan Fu, Yongzhang Luo, Boyuan Ma, 2023, Journal of Translational Medicine.

Prognostic Significance of the Combined Score of Endothelial Expression of Nucleolin and CD31 in Surgically Resected Non-Small Cell Lung Cancer

Yongzhang Luo, X. Hou, Li Zhang, 2013, PloS one.

Insight into the catalytic mechanism of arginine deiminase: Functional studies on the crucial sites

Hao Zhou, Yingbo He, Yongzhang Luo, 2006, Proteins.

The heparin binding motif of endostatin mediates its interaction with receptor nucleolin.

Hubing Shi, Yan Fu, Yongzhang Luo, 2009, Biochemistry.

Unraveling the mysteries of endostatin

Huadong Tang, Yan Fu, Yongzhang Luo, 2009, IUBMB life.

Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin.

Hubing Shi, Yan Fu, Hao Zhou, 2007, Blood.

Oxidative Damage to DNA Constituents by Iron-mediated Fenton Reactions

S. Linn, Yongzhang Luo, E. Henle, 1996, The Journal of Biological Chemistry.

Severe Delayed Postoperative Hyponatremia in a Case of TSH-secreting Pituitary Adenoma: A Case Report

Xiao-hai Liu, Yongzhang Luo, Wang, 2019 .

Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway.

Yan Fu, Yongzhang Luo, Yang Tian, 2020, Cell reports.

NAD+ supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling

Yan Fu, Yongzhang Luo, Yuanchao Gong, 2023, Oncogene.

High expression of CCR5 in melanoma enhances epithelial–mesenchymal transition and metastasis via TGFβ1

Yan Fu, Yongzhang Luo, Jie Liu, 2019, The Journal of pathology.

Lung fibroblasts promote metastatic colonization through upregulation of stearoyl-CoA desaturase 1 in tumor cells

Yan Fu, Yongzhang Luo, Lin Jia, 2018, Oncogene.

Enhancement of tumor uptake and therapeutic efficacy of EGFR‐targeted antibody cetuximab and antibody–drug conjugates by cholesterol sequestration

Yan Fu, Yongzhang Luo, Guanghua Liu, 2015, International journal of cancer.

Voltage‐dependent anion channel 1 is involved in endostatin‐induced endothelial cell apoptosis

Hubing Shi, Yan Fu, Yongzhang Luo, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Endostatin has novel ATPase activity, which its anti-angiogenic and anti-tumor activities

P. Liu, Shan Wang, Yan Fu, 2015 .

The miR-30 Family Inhibits Pulmonary Vascular Hyperpermeability in the Premetastatic Phase by Direct Targeting of Skp2

T. He, Yan Fu, Yongzhang Luo, 2015, Clinical Cancer Research.

Fibrillogenesis of apomyoglobin facilitated by aggregation sequence of yeast Sup35 in various regions

Haochen Zhou, Huadong Tang, Yingbo He, 2005, FEBS letters.

Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways.

Shan Wang, Yan Fu, Yongzhang Luo, 2011, Blood.

Plasma Heat Shock Protein 90alpha as a Biomarker for the Diagnosis of Liver Cancer: An Official, Large-scale, and Multicenter Clinical Trial

Shusen Zheng, Yan Fu, Yongzhang Luo, 2017, EBioMedicine.

Young and Undamaged rMSA Improves the Longevity of Mice

Yan Fu, Yongzhang Luo, Boya Li, 2021, bioRxiv.

Endostatin inhibits the tumorigenesis of hemangioendothelioma via downregulation of CXCL1

T. He, Yan Fu, Yongzhang Luo, 2015, Molecular carcinogenesis.

Specific chemotherapeutic agents induce metastatic behaviour through stromal‐ and tumour‐derived cytokine and angiogenic factor signalling

T. He, Yan Fu, Yongzhang Luo, 2015, The Journal of pathology.

Metformin Inhibits Tumor Metastasis through Suppressing Hsp90α Secretion in an AMPKα1-PKCγ Dependent Manner

Yan Fu, Yongzhang Luo, Caihong Wang, 2020, Cells.

Low stability of nucleocapsid protein in SARS virus.

Yan Fu, Hao Zhou, Yongzhang Luo, 2004, Biochemistry.

Genetic ablation of apolipoprotein A-IV accelerates Alzheimer's disease pathogenesis in a mouse model.

Yingbo He, Yongzhang Luo, Yujie Cui, 2011, The American journal of pathology.

Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion.

Yan Fu, Yongzhang Luo, Yang Tian, 2020, Cell reports.

Adrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cells

Shan Wang, Yan Fu, Yongzhang Luo, 2016, Oncotarget.

Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease

Yan Fu, Yongzhang Luo, Jie Liu, 2023, Signal transduction and targeted therapy.

CXCR7 promotes melanoma tumorigenesis via Src kinase signaling

Yan Fu, Yongzhang Luo, Jie Liu, 2019, Cell Death & Disease.

The N-terminal integrity is critical for the stability and biological functions of endostatin.

Yan Fu, Yongzhang Luo, 2010, Biochemistry.

Combination of MAPK inhibition with photothermal therapy synergistically augments the anti-tumor efficacy of immune checkpoint blockade.

C. Gong, Hubing Shi, Jie Xu, 2021, Journal of controlled release : official journal of the Controlled Release Society.

of endostatin in endothelium via regulating distinct endocytic pathways Cholesterol sequestration by nystatin enhances the uptake and activity

Shan Wang, Yan Fu, Yongzhang Luo, 2013 .

Phase I trial of M2ES, a novel polyethylene glycosylated recombinant human endostatin, plus gemcitabine in advanced pancreatic cancer.

Zhaoshen Li, Yan Fu, Yongzhang Luo, 2014, Molecular and clinical oncology.

Three chemically distinct types of oxidants formed by iron-mediated Fenton reactions in the presence of DNA.

S. Linn, Yongzhang Luo, Y. Luo, 1994, Proceedings of the National Academy of Sciences of the United States of America.