Chiaki Nakano

发表

Biochemical characterization of the water‐soluble squalene synthase from Methylococcus capsulatus and the functional analyses of its two DXXD(E)D motifs and the highly conserved aromatic amino acid residues

S. Sasaki, Kana Ohtake, Naoki Saito, 2014, The FEBS journal.

Identification of the SGR6065 gene product as a sesquiterpene cyclase involved in (+)-epicubenol biosynthesis in Streptomyces griseus

S. Horinouchi, Chiaki Nakano, Y. Ohnishi, 2012, The Journal of Antibiotics.

Biosynthesis of Aliphatic Polyketides by Type III Polyketide Synthase and Methyltransferase in Bacillus subtilis

S. Horinouchi, Chiaki Nakano, N. Funa, 2009, Journal of bacteriology.

The O-Methyltransferase SrsB Catalyzes the Decarboxylative Methylation of Alkylresorcylic Acid during Phenolic Lipid Biosynthesis by Streptomyces griseus

S. Horinouchi, Chiaki Nakano, N. Funa, 2012, Journal of bacteriology.

Characterization of a Novel Sesquiterpene Cyclase Involved in (+)-Caryolan-1-ol Biosynthesis in Streptomyces griseus*

S. Horinouchi, Chiaki Nakano, Y. Ohnishi, 2011, The Journal of Biological Chemistry.

Substrate specificity of Rv3378c, an enzyme from Mycobacterium tuberculosis, and the inhibitory activity of the bicyclic diterpenoids against macrophage phagocytosis.

Chiaki Nakano, T. Hoshino, Takahiro Ootsuka, 2011, Organic & biomolecular chemistry.

Strictly Conserved Residues in Euphorbia tirucalli β‐Amyrin Cyclase: Trp612 Stabilizes Transient Cation through Cation–π Interaction and CH–π Interaction of Tyr736 with Leu734 Confers Robust Local Protein Architecture

Chiaki Nakano, T. Hoshino, Takumi Watanabe, 2018, Chembiochem : a European journal of chemical biology.

Identification of Diterpene Biosynthetic Gene Clusters and Functional Analysis of Labdane-Related Diterpene Cyclases in Phomopsis amygdali

T. Toyomasu, W. Mitsuhashi, T. Dairi, 2008, Bioscience, biotechnology, and biochemistry.

Identification of a New Diterpene Biosynthetic Gene Cluster that Produces O‐Methylkolavelool in Herpetosiphon aurantiacus

Chiaki Nakano, T. Hoshino, Misaki Oshima, 2015, Chembiochem : a European journal of chemical biology.

Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis

E. Oldfield, A. H. Wang, T. Ko, 2014, Journal of the American Chemical Society.

Characterization of the Rv3378c Gene Product, a New Diterpene Synthase for Producing Tuberculosinol and (13R, S)-Isotuberculosinol (Nosyberkol), from the Mycobacterium tuberculosis H37Rv Genome

Chiaki Nakano, T. Hoshino, T. Mitsui, 2011, Bioscience, biotechnology, and biochemistry.

Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton.

T. Dairi, Chiaki Nakano, T. Hoshino, 2005, Chemical communications.

Identification of the First Bacterial Monoterpene Cyclase, a 1,8‐Cineole Synthase, that Catalyzes the Direct Conversion of Geranyl Diphosphate

Chiaki Nakano, Y. Ohnishi, Hyo-Kyoung Kim, 2011, Chembiochem : a European journal of chemical biology.

Synthesis of Isotopically Labelled Oligoprenyl Diphosphates and Their Application in Mechanistic Investigations of Terpene Cyclases

Jeroen S. Dickschat, Chiaki Nakano, T. Hoshino, 2014 .

Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum

E. Oldfield, S. Hsu, T. Ko, 2014, Scientific Reports.

Characterization of the Rv3377c Gene Product, a Type‐B Diterpene Cyclase, from the Mycobacterium tuberculosis H37 Genome

Chiaki Nakano, T. Hoshino, 2009, Chembiochem : a European journal of chemical biology.

Genome Mining Reveals Two Novel Bacterial Sesquiterpene Cyclases: (−)‐Germacradien‐4‐ol and (−)‐epi‐α‐Bisabolol Synthases from Streptomyces citricolor

T. Eguchi, Chiaki Nakano, Y. Ohnishi, 2011, Chembiochem : a European journal of chemical biology.

β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade.

Chiaki Nakano, T. Hoshino, Chika Nakada, 2014, Organic & biomolecular chemistry.

Identification of Novel Sesterterpene/Triterpene Synthase from Bacillus clausii

Y. Murata, T. Shinada, Chiaki Nakano, 2013, ChemBioChem.

Insight into the pathway for biosynthesis of sesquarterpenes in nonpathogenic Mycobacterium species: identification of heptaprenylcycli-14E,18E-diene

Chiaki Nakano, T. Hoshino, Tsutomu Sato, 2012 .

Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases.

Chiaki Nakano, T. Hoshino, Tsutomu Sato, 2011, Organic letters.

Sterol Biosynthesis by a Prokaryote: First in Vitro Identification of the Genes Encoding Squalene Epoxidase and Lanosterol Synthase from Methylococcus capsulatus

Chiaki Nakano, T. Hoshino, M. Onodera, 2007, Bioscience, biotechnology, and biochemistry.

3 4 The O-methyltransferase SrsB catalyzes the decarboxylative methylation of 5 alkylresorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus 6 7 8

S. Horinouchi, Chiaki Nakano, N. Funa, 2012 .

Further Insight into Polycyclization Cascades of Acyclic Geranylfarnesol and its Acetate by Squalene-hopene Cyclase from Alicyclobacillus Acidocaldarius

Chiaki Nakano, T. Hoshino, G. Shi, 2016, Natural product communications.

Enzymatic syntheses of novel carbocyclic scaffolds with a 6,5 + 5,5 ring system by squalene-hopene cyclase.

Chiaki Nakano, T. Hoshino, Takumi Watanabe, 2019, Organic & biomolecular chemistry.

Identification and Characterization of the Linalool/Nerolidol Synthase from Streptomyces clavuligerus

Chiaki Nakano, Y. Ohnishi, Hyo-Kyoung Kim, 2011, Chembiochem : a European journal of chemical biology.

Substrate specificity of the CYC2 enzyme from Kitasatospora griseola: production of sclarene, biformene, and novel bicyclic diterpenes by the enzymatic reactions of labdane- and halimane-type diterpene diphosphates

T. Toyomasu, T. Dairi, Chiaki Nakano, 2010 .