G. Zheng

发表

Development of an engineered thermostable amine dehydrogenase for the synthesis of structurally diverse chiral amines

Jian‐He Xu, Zhilong Wang, Zhi‐Jun Zhang, 2020, Catalysis Science & Technology.

Reductive amination of ketones with ammonium catalyzed by a newly identified Brevibacterium epidermidis strain for the synthesis of (S)-chiral amines

Jian‐He Xu, Chun-Xiu Li, Lei Liu, 2018, Chinese Journal of Catalysis.

Asymmetric Amination of Secondary Alcohols by using a Redox‐Neutral Two‐Enzyme Cascade

Jian‐He Xu, Fei-Fei Chen, G. Zheng, 2015 .

Whole-Cell Biocatalytic Processes with Ionic Liquids

M. Zong, Wenyong Lou, G. Zheng, 2016 .

Myoglobin-Catalyzed Efficient In Situ Regeneration of NAD(P)+ and Their Synthetic Biomimetic for Dehydrogenase-Mediated Oxidations

Ning Li, M. Zong, G. Zheng, 2019, ACS Catalysis.

Direct Access to Medium‐Chain α,ω‐Dicarboxylic Acids by Using a Baeyer–Villiger Monooxygenase of Abnormal Regioselectivity

Jian‐He Xu, Yunpeng Bai, Chun-Xiu Li, 2018, Chembiochem : a European journal of chemical biology.

Biocatalytic Processes for the Synthesis of Chiral Alcohols

Jian‐He Xu, G. Zheng, Y. Ni, 2016 .

Evolution of Glucose Dehydrogenase for Cofactor Regeneration in Bioredox Processes with Denaturing Agents

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2020, Chembiochem : a European journal of chemical biology.

One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia

Huilei Yu, Aitao Li, G. Zheng, 2020, Nature Communications.

Coevolution of the Activity and Thermostability of an ϵ‐Keto Ester Reductase for Better Synthesis of an (R)‐α‐Lipoic Acid Precursor

Jian‐He Xu, Zhi‐Jun Zhang, Qi Chen, 2019, Chembiochem : a European journal of chemical biology.

Asymmetric Reductive Amination of Structurally Diverse Ketones with Ammonia Using a Spectrum-Extended Amine Dehydrogenase

Jian‐He Xu, Dong-Hao Wang, Fei-Fei Chen, 2021, ACS Catalysis.

Reshaping the Active Pocket of Amine Dehydrogenases for Asymmetric Synthesis of Bulky Aliphatic Amines

Jian‐He Xu, Chun-Xiu Li, Lei Liu, 2018 .

Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1

Huilei Yu, Jian‐He Xu, Wenyong Lou, 2017 .

Bioreduction of methyl o-chlorobenzoylformate at 500gL−1 without external cofactors for efficient production of enantiopure clopidogrel intermediate

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2012 .

Stereocomplementary Synthesis of Pharmaceutically Relevant Chiral 2-Aryl-Substituted Pyrrolidines Using Imine Reductases.

Jian‐He Xu, Fei-Fei Chen, Qi Chen, 2020, Organic letters.

Immobilization of Bacillus subtilis esterase by simple cross-linking for enzymatic resolution of dl-menthyl acetate

Jiang Pan, Huilei Yu, Jian‐He Xu, 2011 .

Direct reductive amination of ketones with amines by reductive aminases

Jian‐He Xu, Jing Zhang, Fei-Fei Chen, 2021, Green Synthesis and Catalysis.

Highly efficient bioreduction of 2-hydroxyacetophenone to (S)- and (R)-1-phenyl-1,2-ethanediol by two substrate tolerance carbonyl reductases with cofactor regeneration.

G. Zheng, Wenlong Wei, Jiandong Zhang, 2017, Journal of biotechnology.

An efficient bioprocess for enzymatic production of L-menthol with high ratio of substrate to catalyst using whole cells of recombinant E. coli.

Jiang Pan, Huilei Yu, Jian‐He Xu, 2010, Journal of biotechnology.

Identification of an Imine Reductase for Asymmetric Reduction of Bulky Dihydroisoquinolines.

Jian‐He Xu, G. Zheng, Hao Li, 2017, Organic letters.

Multifunctional Biocatalysis: An Unusual Imine Reductase

Jian‐He Xu, Fei-Fei Chen, G. Zheng, 2022, Engineering Microbiology.

Cloning and Characterization of an Enantioselective l-Menthyl Benzoate Hydrolase from Acinetobacter sp. ECU2040

Jian‐He Xu, Jin Yin, G. Zheng, 2015, Applied Biochemistry and Biotechnology.

Enantioselective Synthesis of Chiral Vicinal Amino Alcohols Using Amine Dehydrogenases

Jian‐He Xu, M. Thompson, N. Turner, 2019, ACS Catalysis.

Optimization and Scale-up of a Bioreduction Process for Preparation of Ethyl (S)-4-Chloro-3-hydroxybutanoate

Jiang Pan, Jian‐He Xu, Q. Ye, 2014 .

A Novel (R)‐Imine Reductase from Paenibacillus lactis for Asymmetric Reduction of 3 H‐Indoles

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2016 .

Efficient synthesis of chiral indolines using an imine reductase from Paenibacillus lactis

Jian‐He Xu, G. Zheng, Hao Li, 2015 .

Reductive Amination of Biobased Levulinic Acid to Unnatural Chiral γ-Amino Acid Using an Engineered Amine Dehydrogenase

Jian‐He Xu, Aitao Li, Lei Liu, 2020 .

Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1.

Jian‐He Xu, X. Qian, G. Zheng, 2014, Chemical communications.

Efficient production of l-menthol in a two-phase system with SDS using an immobilized Bacillus subtilis esterase

Jiang Pan, Jian‐He Xu, Q. Ye, 2014, Bioresources and Bioprocessing.

Stereospecific Reduction of Methyl o‐Chlorobenzoylformate at 300 g⋅L−1 without Additional Cofactor using a Carbonyl Reductase Mined from Candida glabrata

Jian‐He Xu, Linlin Yang, Chun-Xiu Li, 2012 .

Stepwise and combinatorial optimization of enantioselectivity for the asymmetric hydrolysis of 1-(3’,4’-methylenedioxyphenyl)ethyl acetate under use of a cold-adapted Bacillus amyloliquefaciens esterase

T. Imanaka, Jian‐He Xu, G. Zheng, 2014, Biotechnology and Bioprocess Engineering.

Multi-substrate fingerprinting of esterolytic enzymes with a group of acetylated alcohols and statistic analysis of substrate spectrum

Jiang Pan, Huilei Yu, Jian‐He Xu, 2013 .

Efficient synthesis of a chiral precursor for angiotensin-converting enzyme (ACE) inhibitors in high space-time yield by a new reductase without external cofactors.

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2012, Organic letters.

Enantioselective production of (S)-1-phenyl-1,2-ethanediol from dicarboxyesters by recombinant Bacillus subtilis esterase

Jian‐He Xu, Zhilong Wang, Chun-Xiu Li, 2011 .

Engineered Imine Reductase for Larotrectinib Intermediate Manufacture

R. Guo, Jian‐He Xu, Fei-Fei Chen, 2022, ACS Catalysis.

Green access to chiral Vince lactam in a buffer-free aqueous system using a newly identified substrate-tolerant (−)-γ-lactamase

Jian‐He Xu, Jin Yin, G. Zheng, 2016 .

Recent progress on deep eutectic solvents in biocatalysis

Ning Li, Pei Xu, Gao-Wei Zheng, 2017, Bioresources and Bioprocessing.

Discovery of an Imine Reductase for Reductive Amination of Carbonyl Compounds with Sterically Challenging Amines.

Jian‐He Xu, Xingxing Shen, N. Turner, 2023, Journal of the American Chemical Society.

Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor

Jian‐He Xu, Zhen Qin, G. Zheng, 2018, ACS Catalysis.

Identification of a Robust Carbonyl Reductase for Diastereoselectively Building syn-3,5-Dihydroxy Hexanoate: a Bulky Side Chain of Atorvastatin

Jian‐He Xu, G. Zheng, You-Yan Liu, 2017 .

Identification of an ε‐Keto Ester Reductase for the Efficient Synthesis of an (R)‐α‐Lipoic Acid Precursor

Jian‐He Xu, G. Zheng, Wen-Xia Zhang, 2015 .

Efficient production of (R)-(−)-mandelic acid using glutaraldehyde cross-linked Escherichia coli cells expressing Alcaligenes sp. nitrilase

Jiang Pan, Huilei Yu, Jian‐He Xu, 2014, Bioprocess and Biosystems Engineering.

Enzymatic Production of l‐Menthol by a High Substrate Concentration Tolerable Esterase from Newly Isolated Bacillus subtilis ECU0554

Huilei Yu, Jian‐He Xu, G. Zheng, 2009 .

Enantioselective Hydrolysis of dl-Menthyl Benzoate by Cell-Free Extract of Newly Isolated Acinetobacter sp. ECU2040

Jiang Pan, Jian‐He Xu, Jin Yin, 2013, Applied Biochemistry and Biotechnology.

Enzymatic resolution of a chiral chlorohydrin precursor for (R)-α-lipoic acid synthesis via lipase catalyzed enantioselective transacylation with vinyl acetate

Jian‐He Xu, G. Zheng, Zhirong Zhu, 2014 .

New opportunities for biocatalysis: driving the synthesis of chiral chemicals.

Jian-He Xu, Gao-Wei Zheng, Jian‐He Xu, 2011, Current opinion in biotechnology.

Efficient production of (R)-o-chloromandelic acid by deracemization of o-chloromandelonitrile with a new nitrilase mined from Labrenzia aggregata

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2012, Applied Microbiology and Biotechnology.

Engineering of a novel carbonyl reductase with coenzyme regeneration in E. coli for efficient biosynthesis of enantiopure chiral alcohols.

M. Zong, Wenyong Lou, Hong Wu, 2016, Journal of biotechnology.

Dynamic interplay between dislocations and precipitates in creep aging of an Al-Zn-Mg-Cu alloy

Heng Li, G. Zheng, C. Lei, 2019, Advances in Manufacturing.

Target-oriented discovery of a new esterase-producing strain Enterobacter sp. ECU1107 for whole cell-catalyzed production of (2S,3R)-3-phenylglycidate as a chiral synthon of Taxol

Jiang Pan, Huilei Yu, Jian‐He Xu, 2013, Applied Microbiology and Biotechnology.

Separation of enantiopure m-substituted 1-phenylethanols in high space-time yield using Bacillus subtilis esterase

Jian‐He Xu, Zhi‐Jun Zhang, G. Zheng, 2013 .

Improved biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by adding L-glutamine plus glycine instead of NAD+ in β-cyclodextrin-water system.

Yucai He, Yun Lu, H. Rui, 2015, Bioresource Technology.

Continuous-Flow Microreactor-Enhanced Clean NAD+ Regeneration for Biosynthesis of 7-Oxo-lithocholic Acid

Jian‐He Xu, Yunpeng Bai, G. Zheng, 2021, ACS Sustainable Chemistry & Engineering.

Halogenation/Dehalogenation/Heteroatom Oxidation

J. Damborský, R. Chaloupkova, Jiang Pan, 2012 .

Bioamination of alkane with ammonium by an artificially designed multienzyme cascade.

Chao Yang, Huilei Yu, Jian‐He Xu, 2018, Metabolic engineering.

Efficient production of (R)-o-chloromandelic acid by deracemization of o-chloromandelonitrile with a new nitrilase mined from Labrenzia aggregata

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2012, Applied Microbiology and Biotechnology.

Efficient Synthesis of Methyl 3-Acetoxypropionate by a Newly Identified Baeyer-Villiger Monooxygenase

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2019, Applied and Environmental Microbiology.

One-pot enzyme cascade for controlled synthesis of furan carboxylic acids from 5-hydroxymethylfurfural via H2O2 internal recycling.

Ning Li, M. Zong, G. Zheng, 2019, ChemSusChem.

Rational Engineering of Formate Dehydrogenase Substrate/Cofactor Affinity for Better Performance in NADPH Regeneration

Jiang Pan, Jian‐He Xu, Qi Chen, 2020, Applied Biochemistry and Biotechnology.

An Ammonium-Formate-Driven Trienzymatic Cascade for ω-Transaminase-Catalysed (R)-Selective Amination.

Jian‐He Xu, Jianping Wu, Zhi‐Jun Zhang, 2019, The Journal of organic chemistry.

Regiospecific C–H amination of (−)-limonene into (−)-perillamine by multi-enzymatic cascade reactions

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2022, Bioresources and Bioprocessing.

Efficient synthesis of an ε-hydroxy ester in a space–time yield of 1580 g L−1 d−1 by a newly identified reductase RhCR

Jian‐He Xu, G. Zheng, Y. Ni, 2014 .

Engineering a norcoclaurine synthase for one-step synthesis of (S)-1-aryl-tetrahydroisoquinolines

Jian‐He Xu, Fei-Fei Chen, Qi Chen, 2023, Bioresources and Bioprocessing.

Sustainable and Robust Closed-Loop Enzymatic Platform for Continuous/Semi-continuous Synthesis of Ursodeoxycholic Acid

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2022, ACS Sustainable Chemistry & Engineering.

Direct Access to Medium‐Chain α,ω‐Dicarboxylic Acids by Using a Baeyer–Villiger Monooxygenase of Abnormal Regioselectivity

Jian‐He Xu, Yunpeng Bai, Chun-Xiu Li, 2018, Chembiochem : a European journal of chemical biology.

De Novo Multienzyme Synthetic Pathways for Lactic Acid Production

Chun-Xiu Li, Qi Chen, G. Zheng, 2024, ACS Catalysis.

Engineering of halide methyltransferases for synthesis of SAE and its application in biosynthesis of ethyl vanillin

Qi Chen, G. Zheng, Jian-He Xu, 2023, Molecular Catalysis.