H. Mimuro

发表

Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach.

G. Rieder, C. Sasakawa, S. Koyasu, 2007, Cell host & microbe.

BabA-mediated Adherence Is a Potentiator of the Helicobacter pylori Type IV Secretion System Activity*

C. Sasakawa, R. Haas, H. Mimuro, 2011, The Journal of Biological Chemistry.

Shigella are versatile mucosal pathogens that circumvent the host innate immune system.

C. Sasakawa, Taira Kobayashi, Takahito Sanada, 2011, Current opinion in immunology.

Pleurotolysin, a Novel Sphingomyelin-specific Two-component Cytolysin from the Edible Mushroom Pleurotus ostreatus, Assembles into a Transmembrane Pore Complex*

H. Mimuro, Kiyoshi Ito, T. Tomita, 2004, Journal of Biological Chemistry.

Neural Wiskott–Aldrich syndrome protein (N‐WASP) is the specific ligand for Shigella VirG among the WASP family and determines the host cell type allowing actin‐based spreading

C. Sasakawa, T. Takenawa, S. Suetsugu, 2002, Cellular microbiology.

Shigella targets epithelial tricellular junctions and uses a noncanonical clathrin-dependent endocytic pathway to spread between cells.

C. Sasakawa, S. Shimizu, K. Nakayama, 2012, Cell host & microbe.

Shigella deliver an effector protein to trigger host microtubule destabilization, which promotes Rac1 activity and efficient bacterial internalization

C. Sasakawa, E. Katayama, Sei Yoshida, 2002, The EMBO journal.

Grb2 is a key mediator of helicobacter pylori CagA protein activities.

C. Sasakawa, R. Haas, H. Mimuro, 2002, Molecular cell.

A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens.

C. Sasakawa, H. Kiyono, Taira Kobayashi, 2011, Cell host & microbe.

The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling.

J. Bertin, C. Sasakawa, D. Philpott, 2014, Cell host & microbe.

Group A Streptococcus establishes pharynx infection by degrading the deoxyribonucleic acid of neutrophil extracellular traps

Tetsuya Hayashi, M. Nangaku, Chihiro Aikawa, 2020, Scientific Reports.

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response

C. Sasakawa, T. Mizushima, J. Inoue, 2012, Nature.

CBL-C E3 ubiquitin ligase acts as a host defense to mediate ubiquitin-proteasomal degradation of enteropathogenic Escherichia coli Tir protein

C. Sasakawa, A. Abe, H. Mimuro, 2021, bioRxiv.

Cell Host & Microbe Tecpr 1 in Selective Autophagy formation in mammalian cells

C. Sasakawa, H. Kiyono, Taira Kobayashi, 2011 .

The inflammatory response in Helicobacter pylori-infected gastric tissue is mediated by cag pathogenicity island (PAI)-dependent activation of nuclear factor-κB (NF-κB). Phosphatidylinositol 3-kinase (PI3K)/Akt signaling is known to play a role in NF-κB activation, but little information is availabl

Shigeki, Chihiro, C. Ishikawa, 2019 .

BMC Microbiology BioMed Central

C. Sasakawa, C. Ishikawa, M. Senba, 2009 .

Control of epithelial cell structure and developmental fate: lessons from Helicobacter pylori.

C. Sasakawa, D. Berg, H. Mimuro, 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

Epidemiological study of gastric Helicobacter spp. in dogs with gastrointestinal disease in Japan and diversity of Helicobacter heilmannii sensu stricto.

T. Sekizaki, H. Tsujimoto, K. Uchida, 2017, Veterinary journal.

Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

C. Sasakawa, G. Núñez, Shiho Suzuki, 2014, Proceedings of the National Academy of Sciences.

Manipulation of autophagy by bacteria for their own benefit

C. Sasakawa, H. Mimuro, H. Ashida, 2011, Microbiology and immunology.

Autophagy targeting of Listeria monocytogenes and the bacterial countermeasure

C. Sasakawa, T. Chakraborty, T. Hain, 2011, Autophagy.

Attenuated CagA Oncoprotein in Helicobacter pylori from Amerindians in Peruvian Amazon*

M. Oyama, C. Sasakawa, H. Kozuka-Hata, 2011, The Journal of Biological Chemistry.

The Journal of Experimental Medicine CORRESPONDENCE

A. Abe, Sei Yoshida, S. Koyasu, 2005 .

Shigella Manipulates Host Immune Responses by Delivering Effector Proteins with Specific Roles

C. Sasakawa, H. Mimuro, H. Ashida, 2015, Front. Immunol..

GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites

M. Ishii, K. Takeda, J. Aoki, 2019, Nature.

Id2-, RORγt-, and LTβR-independent initiation of lymphoid organogenesis in ocular immunity

S. Akira, C. Sasakawa, S. Fukuyama, 2009, The Journal of experimental medicine.

Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity

K. Ishii, H. Kiyono, Shintaro Sato, 2018, Mucosal Immunology.

Shigella-induced necrosis and apoptosis of U937 cells and J774 macrophages.

A. Kuwae, T. Nonaka, S. Imajoh-ohmi, 2003, Microbiology.

Shigella infection of intestinal epithelium and circumvention of the host innate defense system.

C. Sasakawa, H. Mimuro, H. Ashida, 2009, Current topics in microbiology and immunology.

Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells

H. Madhyastha, H. Kikuchi, H. Mimuro, 2022, Fundamental Toxicological Sciences.

Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA.

J. D. Di Santo, Tamotsu Kato, H. Ohno, 2020, Immunity.

Shigella hijacks the glomulin–cIAPs–inflammasome axis to promote inflammation

C. Sasakawa, T. Mizushima, Shiho Suzuki, 2018, EMBO reports.

Shigella Invasion of Macrophage Requires the Insertion of IpaC into the Host Plasma Membrane

C. Sasakawa, K. Tamano, A. Kuwae, 2001, The Journal of Biological Chemistry.

Helicobacter pylori induces somatic mutations in TP53 via overexpression of CHAC1 in infected gastric epithelial cells

P. Tummala, Y. Eishi, K. Uchida, 2018, FEBS open bio.

[Strategy of Helicobacter pylori to enhance colonization of the stomach].

H. Mimuro, 2009, Nihon saikingaku zasshi. Japanese journal of bacteriology.

Shigella effector IpaH4.5 targets 19S regulatory particle subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation

C. Sasakawa, S. Murata, Jun Hamazaki, 2018, Cellular microbiology.

Interaction of CagA with Crk plays an important role in Helicobacter pylori–induced loss of gastric epithelial cell adhesion

C. Sasakawa, Morag Park, Tadashi Yamamoto, 2005, The Journal of experimental medicine.

Cell death and infection: A double-edged sword for host and pathogen survival

Minsoo Kim, Hiroshi Ashida, C. Sasakawa, 2011, The Journal of cell biology.

Characterization of morphological conversion of Helicobacter pylori under anaerobic conditions

H. Kiyono, S. Kaneto, Takahito Sanada, 2018, Microbiology and immunology.

Analysis of Genetic Relatedness between Gastric and Oral Helicobacter pylori in Patients with Early Gastric Cancer Using Multilocus Sequence Typing

S. Terai, S. Takenaka, J. Yokoyama, 2023, International journal of molecular sciences.

Listeria monocytogenes ActA-mediated escape from autophagic recognition

C. Sasakawa, I. Nakagawa, A. Kakizuka, 2009, Nature Cell Biology.

GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites

M. Ishii, K. Takeda, J. Aoki, 2019, Nature.

Bacteria and host interactions in the gut epithelial barrier.

Minsoo Kim, Hiroshi Ashida, C. Sasakawa, 2011, Nature chemical biology.

Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity

T. Kaisho, H. Kiyono, J. Kunisawa, 2020, Mucosal Immunology.

Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages

C. Sasakawa, G. Núñez, N. Inohara, 2007, PLoS pathogens.

Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo.

C. Sasakawa, R. Peek, A. Franco, 2009, Cancer research.

Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis

C. Sasakawa, H. Kiyono, S. Koyasu, 2007, Proceedings of the National Academy of Sciences.

Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity

T. Kaisho, H. Kiyono, J. Kunisawa, 2020, Mucosal Immunology.

Bacterial interactions with the host epithelium.

Minsoo Kim, Hiroshi Ashida, C. Sasakawa, 2010, Cell host & microbe.

Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin

K. Tsumoto, Makoto Nakakido, S. Nagatoishi, 2018, Communications Biology.

Shigella Type III Secretion Protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation Independently of Pkcδ

C. Sasakawa, G. Núñez, Shiho Suzuki, 2014, PLoS pathogens.

Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells.

H. Nishitoh, S. Imajoh-ohmi, H. Kikuchi, 2015, Biochemical and biophysical research communications.

Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation.

C. Sasakawa, D. Berg, S. Koyasu, 2009, Cell host & microbe.

Histone acetyltransferase p300/CBP‐associated factor is an effective suppressor of secretory immunoglobulin synthesis in immature B cells

H. Nishitoh, S. Imajoh-ohmi, H. Kikuchi, 2015, Microbiology and immunology.

Transmission of Helicobacter pylori between a human and two dogs: A case report

H. Tsujimoto, N. Kato, K. Uchida, 2021, Helicobacter.

Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression.

H. Nishitoh, S. Imajoh-ohmi, H. Kikuchi, 2015, Biochemical and biophysical research communications.

Shigella deploy multiple countermeasures against host innate immune responses.

C. Sasakawa, C. Punginelli, Shiho Suzuki, 2011, Current opinion in microbiology.

A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment

Tetsuya Hayashi, K. Nakai, Y. Yamaoka, 2021, Nature Communications.

The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection.

C. Sasakawa, T. Mizushima, Taira Kobayashi, 2013, Cell host & microbe.

Helicobacter pylori-Induced Interleukin-12 p40 Expression

C. Sasakawa, T. Hirayama, C. Ishikawa, 2009, Infection and Immunity.

Epidemiological study on feline gastric Helicobacter spp. in Japan

T. Sekizaki, H. Tsujimoto, K. Uchida, 2017, The Journal of veterinary medical science.

A Novel Multiplex PCR Discriminates Bacillus anthracis and Its Genetically Related Strains from Other Bacillus cereus Group Species

T. Ezaki, H. Ogawa, Naomi Ohnishi, 2015, PloS one.

A Rice-Based Oral Cholera Vaccine Induces Macaque-Specific Systemic Neutralizing Antibodies but Does Not Influence Pre-Existing Intestinal Immunity1

C. Sasakawa, H. Kiyono, F. Ono, 2009, The Journal of Immunology.

Disease Severity Is Associated with Differential Gene Expression at the Early and Late Phases of Infection in Nonhuman Primates Infected with Different H5N1 Highly Pathogenic Avian Influenza Viruses

H. Kitano, C. Sasakawa, Eiryo Kawakami, 2014, Journal of Virology.

Rho Family Gtpase Cdc42 Is Essential for the Actin-Based Motility of Shigella in Mammalian Cells

C. Sasakawa, T. Takenawa, Y. Takai, 2000, The Journal of experimental medicine.

Profilin Is Required for Sustaining Efficient Intra- and Intercellular Spreading of Shigella flexneri *

C. Sasakawa, T. Takenawa, S. Suetsugu, 2000, The Journal of Biological Chemistry.

Mutational diversity in mutY deficient Helicobacter pylori and its effect on adaptation to the gastric environment.

Tetsuya Hayashi, K. Nakai, Y. Ogura, 2020, Biochemical and biophysical research communications.

Helicobacter small RNA regulates host adaptation and carcinogenesis

Tetsuya Hayashi, K. Nakai, Y. Yamaoka, 2020, bioRxiv.

Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection

C. Sasakawa, M. Fukayama, Taira Kobayashi, 2014, Nature Communications.

A BACTERIAL EFFECTOR TARGETS MAD 2 L 2 , AN APC INHIBITOR , TO MODULATE HOST CELL

G. Rieder, C. Sasakawa, S. Kotani, 2009 .

Helicobacter pylori-Induced Interleukin-12 p40 Expression

C. Sasakawa, T. Hirayama, C. Ishikawa, 2009, Infection and Immunity.

Structural definition on the surface of Helicobacter pylori type IV secretion apparatus

C. Sasakawa, H. Mimuro, Toshihiko Suzuki, 2003, Cellular microbiology.

Chalcone skeleton promotes transcription of gp91‐phox gene but inhibits expression of gp91‐phox protein, and hydroxyl groups in hydroxychalcones participate in the stable expression of gp91‐phox protein

H. Madhyastha, H. Kikuchi, H. Mimuro, 2019, Microbiology and immunology.

Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells.

H. Kikuchi, H. Mimuro, F. Kuribayashi, 2018, Biochemical and biophysical research communications.

Virulence factors of Helicobacter pylori.

R. Peek, S. Backert, H. Mimuro, 2010 .

Complete Genome Sequence of Helicobacter pylori Strain ATCC 43504, a Type Strain That Can Infect Gerbils

Tetsuya Hayashi, I. Nakagawa, F. Maruyama, 2020, Microbiology Resource Announcements.

Thiamin transport in Helicobacter pylori lacking the de novo synthesis of thiamin.

H. Mimuro, H. Konno, R. Uchiyama, 2019, Microbiology.

Reinforcement of epithelial cell adhesion to basement membrane by a bacterial pathogen as a new infectious stratagem

C. Sasakawa, H. Mimuro, Minsoo Kim, 2010, Virulence.

Interaction of CagA with Crk plays an important role in Helicobacter pylori–induced loss of gastric epithelial cell adhesion

C. Sasakawa, Morag Park, H. Mimuro, 2005, The Journal of experimental medicine.

The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin1.

A. Miyawaki, C. Sasakawa, C. Punginelli, 2010, Biochemical and biophysical research communications.

GCN5-deficiency remarkably enhances the sensitivity of B cells in response to 4-nitroquinoline 1-oxide

H. Kikuchi, H. Mimuro, F. Kuribayashi, 2016 .

GCN 5-de fi ciency remarkably enhances the sensitivity of B cells in response to 4-nitroquinoline 1-oxide

H. Kikuchi, H. Mimuro, F. Kuribayashi, 2016 .

Monotherapy with a novel intervenolin derivative, AS‐1934, is an effective treatment for Helicobacter pylori infection

M. Kawada, M. Shibasaki, Takumi Watanabe, 2018, Helicobacter.

Bacteria and host interactions in the gut epithelial barrier.

C. Sasakawa, H. Mimuro, Minsoo Kim, 2011, Nature chemical biology.

Disease Severity Is Associated with Differential Gene Expression at the Early and Late Phases of Infection in Nonhuman Primates Infected with Different H5N1 Highly Pathogenic Avian Influenza Viruses

H. Kitano, C. Sasakawa, Eiryo Kawakami, 2014, Journal of Virology.

Helicobacter pylori-Induced Interleukin-12 p40 Expression

C. Sasakawa, T. Hirayama, C. Ishikawa, 2011, Infection and Immunity.

Bacterial interactions with the host epithelium.

C. Sasakawa, H. Mimuro, Minsoo Kim, 2010, Cell host & microbe.

Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin

K. Tsumoto, Makoto Nakakido, S. Nagatoishi, 2018, Communications Biology.

Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN

A. Abe, Sei Yoshida, S. Koyasu, 2009, The Journal of experimental medicine.