A. Leber

发表

Modeling the Mechanisms by Which HIV-Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa

Stanca M. Ciupe, J. Bassaganya-Riera, R. Hontecillas, 2017, PloS one.

Ordinary Differential Equations (ODEs) Based Modeling

Raquel Hontecillas, Josep Bassaganya-Riera, Vida Abedi, 2016 .

Preclinical Studies: Efficacy and Safety

J. Bassaganya-Riera, R. Hontecillas, M. Ehrich, 2018 .

Modulation of Immune Signaling and Metabolism Highlights Host and Fungal Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis

Shiv D. Kale, J. Bassaganya-Riera, R. Hontecillas, 2017, Scientific Reports.

Use of Computational Modeling in Immunological Research

K. Wendelsdorf, J. Bassaganya-Riera, R. Hontecillas, 2016 .

Activation of NLRX1 by NX-13 Alleviates Inflammatory Bowel Disease through Immunometabolic Mechanisms in CD4+ T Cells

J. Bassaganya-Riera, R. Hontecillas, V. Zoccoli-Rodriguez, 2019, The Journal of Immunology.

Abscisic Acid Standardized Fig (Ficus carica) Extracts Ameliorate Postprandial Glycemic and Insulinemic Responses in Healthy Adults

J. Bassaganya-Riera, R. Hontecillas, F. Atkinson, 2019, Nutrients.

Activation of LANCL2 by BT-11 Ameliorates IBD by Supporting Regulatory T Cell Stability Through Immunometabolic Mechanisms.

J. Bassaganya-Riera, R. Hontecillas, V. Zoccoli-Rodriguez, 2018, Inflammatory bowel diseases.

High-resolution computational modeling of immune responses in the gut

J. Bassaganya-Riera, R. Hontecillas, S. Hoops, 2019, GigaScience.

Latent-Based Imputation of Laboratory Measures from Electronic Health Records: Case for Complex Diseases

J. Bassaganya-Riera, R. Hontecillas, V. Abedi, 2018, bioRxiv.

Abscisic Acid: A Novel Nutraceutical for Glycemic Control

J. Bassaganya-Riera, R. Hontecillas, A. Carbo, 2017, Front. Nutr..

Modeling the Dynamics of T Helper 17 Induction and Differentiation

J. Bassaganya-Riera, R. Hontecillas, S. Hoops, 2015 .

Nlrx1-Regulated Defense and Metabolic Responses to Aspergillus fumigatus Are Morphotype and Cell Type Specific

Shiv D. Kale, J. Bassaganya-Riera, R. Hontecillas, 2021, Frontiers in Immunology.

From Nutritional Immunology to Drug Development

J. Bassaganya-Riera, R. Hontecillas, V. Abedi, 2018 .

The Safety, Tolerability, and Pharmacokinetics Profile of BT-11, an Oral, Gut-Restricted Lanthionine Synthetase C-Like 2 Agonist Investigational New Drug for Inflammatory Bowel Disease: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial.

J. Bassaganya-Riera, R. Hontecillas, M. Ehrich, 2019, Inflammatory bowel diseases.

Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1

J. Bassaganya-Riera, R. Hontecillas, M. Ehrich, 2019, Drug and chemical toxicology.

First-in-class topical therapeutic omilancor ameliorates disease severity and inflammation through activation of LANCL2 pathway in psoriasis

J. Bassaganya-Riera, R. Hontecillas, Nuria Tubau-Juni, 2021, Scientific Reports.

Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle

J. Bassaganya-Riera, R. Hontecillas, B. Goodpaster, 2020, Scientific Reports.

Multi-Resolution Sensitivity Analysis of Model of Immune Response to Helicobacter pylori Infection via Spatio-Temporal Metamodeling

Wenjing Wang, Xi Chen, Guangrui Xie, 2019, Front. Appl. Math. Stat..

Modeling-Enabled Systems Nutritional Immunology

Raquel Hontecillas, Josep Bassaganya-Riera, Vida Abedi, 2016, Front. Nutr..

Nonclinical Toxicology and Toxicokinetic Profile of an Oral Lanthionine Synthetase C-Like 2 (LANCL2) Agonist, BT-11

Jennifer L Davis, J. Bassaganya-Riera, R. Hontecillas, 2019, International journal of toxicology.

Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients.

B. Leber, A. Neri, M. Ferrarini, 2021, Cell reports.

Oral Treatment with BT-11 Ameliorates Inflammatory Bowel Disease by Enhancing Regulatory T Cell Responses in the Gut

J. Bassaganya-Riera, R. Hontecillas, A. Leber, 2019, The Journal of Immunology.

Development of Synthetic Patient Populations and In Silico Clinical Trials

Raquel Hontecillas, Josep Bassaganya-Riera, Vida Abedi, 2018 .

Identification of new regulatory genes through expression pattern analysis of a global RNA-seq dataset from a Helicobacter pylori co-culture system

J. Bassaganya-Riera, R. Hontecillas, C. Philipson, 2020, Scientific Reports.

Computer-Aided Drug Discovery

Raquel Hontecillas, Josep Bassaganya-Riera, Pinyi Lu, 2018 .

Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia

B. Leber, M. Bhatia, R. Foley, 2023, Cell reports. Medicine.

Phase III Placebo-Controlled, Randomized Clinical Trial With Synthetic Crohn's Disease Patients to Evaluate Treatment Response

Raquel Hontecillas, Josep Bassaganya-Riera, Vida Abedi, 2016 .

S1076 Efficacy and Safety of Omilancor in a Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Crohn’s Disease

J. Bassaganya-Riera, R. Hontecillas, A. Leber, 2023, American Journal of Gastroenterology.

S1078 Transcriptional Analysis of Colonic Biopsies From Patients With Ulcerative Colitis Treated With Omilancor

J. Bassaganya-Riera, R. Hontecillas, A. Leber, 2023, American Journal of Gastroenterology.

Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle

J. Bassaganya-Riera, R. Hontecillas, B. Goodpaster, 2020, Scientific Reports.

Validation of lanthionine synthetase C-like 2 (LANCL2) as a therapeutic target for systemic lupus erythematosus

J. Bassaganya-Riera, R. Hontecillas, A. Leber, 2019, Journal of Immunology.