Fangfang Zhou

H. van Dam, Min Zheng, Bing Yang, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bisindoylmaleimide I enhances osteogenic differentiation

Fangfang Zhou, Long Zhang, Huizhe Huang, 2012, Protein & Cell.

LRP8 mediates Wnt/β‐catenin signaling and controls osteoblast differentiation

P. ten Dijke, Fangfang Zhou, Long Zhang, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation

H. van Dam, T. van Laar, P. ten Dijke, 2011, Molecular biology of the cell.

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling

T. Sixma, P. ten Dijke, Fangfang Zhou, 2017, The EMBO journal.

Umbilical cord-derived mesenchymal stem cells promote proliferation and migration in MCF-7 and MDA-MB-231 breast cancer cells through activation of the ERK pathway.

Kui Liu, Wenkai Qi, W. Zhai, 2015, Oncology reports.

Protein N-myristoylation: functions and mechanisms in control of innate immunity

Jiang Ren, Fangfang Zhou, Long Zhang, 2021, Cellular & Molecular Immunology.

SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death

P. Dijke, Fangfang Zhou, Feng Xie, 2017, Cell Death and Differentiation.

Wnt/β-catenin signal pathway stabilizes APP intracellular domain (AICD) and promotes its transcriptional activity.

T. van Laar, Fangfang Zhou, Long Zhang, 2011, Biochemical and biophysical research communications.

SARS-CoV-2 Omicron variant: recent progress and future perspectives

Shu Wan, Xiang Li, Fangfang Zhou, 2022, Signal Transduction and Targeted Therapy.

Serum miR-1301-3p, miR-335-5p, miR-28-5p, and their target B7-H3 may serve as novel biomarkers for colorectal cancer.

Fangfang Zhou, Lei Wang, Minyi Xu, 2019, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

Cistanche tubulosa Phenylethanoid Glycosides Induce Apoptosis of Hepatocellular Carcinoma Cells by Mitochondria-Dependent and MAPK Pathways and Enhance Antitumor Effect through Combination with Cisplatin

Jinyao Li, Weilan Wang, L. Xia, 2021, Integrative cancer therapies.

Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression.

P. ten Dijke, Fangfang Zhou, Long Zhang, 2012, Biochemical and biophysical research communications.

Cytotoxic effects of 4-methylimidazole on bone marrow mesenchymal stem cells in vitro.

Wenkai Qi, Tao Li, Yanling Ding, 2015, American journal of translational research.

The Association of GSK3β with E2F1 Facilitates Nerve Growth Factor-induced Neural Cell Differentiation*

Fangfang Zhou, Long Zhang, Y. Gong, 2008, Journal of Biological Chemistry.

APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells

Theo van Laar, Fangfang Zhou, Long Zhang, 2011, Protein & Cell.

STING, a critical contributor to SARS-CoV-2 immunopathology

Fangfang Zhou, Long Zhang, Heyu Li, 2022, Signal Transduction and Targeted Therapy.

Liver microRNA-29b-3p positively correlates with relative enhancement values of magnetic resonance imaging and represses liver fibrosis.

Fangfang Zhou, Xijun Gong, Xiaolin Wang, 2020, Journal of biochemistry.

ADP-riboxanation: a new pyroptosis evasion strategy

Fangfang Zhou, Long Zhang, Heyu Li, 2021, Journal of molecular cell biology.

A systematic review of SARS-CoV-2 vaccine candidates

Min Zheng, Fangfang Zhou, Long Zhang, 2020, Signal Transduction and Targeted Therapy.

Chemical composition, antioxidant and antitumor activities of sub-fractions of wild and cultivated Pleurotus ferulae ethanol extracts

Jinyao Li, Fangfang Zhou, Jinyu Li, 2018, PeerJ.

Capparis spinosa Fruit Ethanol Extracts Exert Different Effects on the Maturation of Dendritic Cells

Jianhua Yang, Jinyao Li, Ji Ma, 2017, Molecules.

The Breast Cancer Stem Cells Traits and Drug Resistance

Fangfang Zhou, Long Zhang, Xuli Meng, 2021, Frontiers in Pharmacology.

Coronavirus in Continuous Flux: From SARS‐CoV to SARS‐CoV‐2

Fangfang Zhou, Long Zhang, Tong Dai, 2020, Advanced science.

Targeted Anti‐Tumor Immunotherapy Using Tumor Infiltrating Cells

Fangfang Zhou, Xiaoxue Zhou, Feng Xie, 2021, Advanced science.

Chemoresistance and Metastasis in Breast Cancer Molecular Mechanisms and Novel Clinical Strategies

Fangfang Zhou, Long Zhang, Meiyu Fang, 2021, Frontiers in Oncology.

A Dual Role of Type I Interferons in Antitumor Immunity

Aijun Wang, Fangfang Zhou, Suping Zhang, 2020, Advanced biosystems.

Involvement of inflammation and its related microRNAs in hepatocellular carcinoma

Tong Li, Fangfang Zhou, Long Zhang, 2016, Oncotarget.

Let-7 a inhibits growth and migration of breast cancer cells by targeting HMGA 1

Kui Liu, Wenkai Qi, Chun-liu Zhang, 2022 .

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

Jeff Porter, C. Mickanin, B. Snaar-Jagalska, 2012, Nature Cell Biology.

Methods and Technologies for Exosome Isolation and Characterization

Mengdi Zhang, Zhengkui Zhang, Fangfang Zhou, 2018, Small Methods.

Cuproptosis: a new form of programmed cell death

Yongqiang Wang, Fangfang Zhou, Long Zhang, 2022, Cellular & Molecular Immunology.

The intersection of COVID-19 and cancer: signaling pathways and treatment implications

Jiang Ren, Fangfang Zhou, Long Zhang, 2021, Molecular cancer.

Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer.

P. ten Dijke, Fangfang Zhou, Long Zhang, 2013, Trends in biochemical sciences.

GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb

Hans van Dam, H. van Dam, T. van Laar, 2011, Molecular biology of the cell.

The regulation of TGF-β/SMAD signaling by protein deubiquitination

H. van Dam, Fangfang Zhou, Feng Xie, 2014, Protein & Cell.

Liquid–liquid phase separation in human health and diseases

Fangfang Zhou, Long Zhang, Tong Dai, 2021, Signal Transduction and Targeted Therapy.

Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity.

Fangfang Zhou, Shixian Lin, Jingxian Li, 2020, Molecular cell.

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis

S. Dooley, H. van Dam, P. ten Dijke, 2017, Nature Communications.

USP4 is regulated by Akt phosphorylation and deubiquitylates TGF-beta type I receptor

C. Mickanin, P. Dijke, K. Sheppard, 2012 .

Fusobacterium nucleatum prevents apoptosis in colorectal cancer cells via the ANO1 pathway

Fangfang Zhou, Lei Wang, Minyi Xu, 2019, Cancer management and research.

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

Craig Mickanin, Yihao Li, A. Bauer, 2013, Molecular cell.

Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID‐19 Therapy

Aijun Wang, T. Pan, Fangfang Zhou, 2021, Advanced materials.

Exosomes in head and neck cancer: Roles, mechanisms and applications.

Fangfang Zhou, Xiaoxue Zhou, Feng Xie, 2020, Cancer letters.

The function and clinical application of extracellular vesicles in innate immune regulation

Fangfang Zhou, Xiaoxue Zhou, Feng Xie, 2020, Cellular & Molecular Immunology.

Fas-associated Factor 1 Is a Scaffold Protein That Promotes β-Transducin Repeat-containing Protein (β-TrCP)-mediated β-Catenin Ubiquitination and Degradation*

H. van Dam, P. ten Dijke, Fangfang Zhou, 2012, The Journal of Biological Chemistry.

Molecular insights into tumour metastasis: tracing the dominant events

H. van Dam, Fangfang Zhou, Long Zhang, 2017, The Journal of pathology.

TGF-&bgr; signaling in cancer metastasis

H. van Dam, Fangfang Zhou, Feng Xie, 2018, Acta biochimica et biophysica Sinica.

Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling

M. Goumans, R. Tollenaar, P. Devilee, 2014, Nature Communications.

RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation.

Jeff Porter, C. Mickanin, H. van Dam, 2012, Molecular cell.

Myostatin Gene Mutated Mice Induced with TALE Nucleases

Hongyan Chen, D. Lu, Fangfang Zhou, 2015, Animal biotechnology.

The regulation of TGF-β/SMAD signaling by protein deubiquitination

H. van Dam, Fangfang Zhou, Feng Xie, 2014, Protein & Cell.

Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.

Fangfang Zhou, Bing-lin Chen, E. Sun, 2019, Oncology letters.

Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis.

Tong Liu, Yihai Cao, Fangfang Zhou, 2020, Cell reports.

Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity

T. Pan, Fangfang Zhou, Long Zhang, 2021, Nature Cell Biology.

The way of SARS-CoV-2 vaccine development: success and challenges

Fangfang Zhou, Long Zhang, Tong Dai, 2021, Signal Transduction and Targeted Therapy.

AMBRA1 Promotes TGFβ Signaling via Nonproteolytic Polyubiquitylation of Smad4

M. Hung, Xin-Hua Feng, Jianping Jin, 2021, Cancer Research.

Ubiquitin-specific Protease 4 Mitigates Toll-like/Interleukin-1 Receptor Signaling and Regulates Innate Immune Activation*

H. van Dam, P. ten Dijke, Fangfang Zhou, 2012, The Journal of Biological Chemistry.

The Crosstalk Between Hippo-YAP Pathway and Innate Immunity

Fangfang Zhou, Suping Zhang, Shuai Wang, 2020, Frontiers in Immunology.

Tumor-derived exosomes antagonize innate antiviral immunity

H. van Dam, Fangfang Zhou, Feng Xie, 2018, Nature Immunology.

Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7

Chen Ding, H. van Dam, Min Zheng, 2017, Nature Communications.

An effective platform for cancer immunotherapy: pooled knockin targeting for genome engineering

Fangfang Zhou, Long Zhang, Ke Jin, 2020, Signal Transduction and Targeted Therapy.

Determining TGF-β Receptor Levels in the Cell Membrane.

P. ten Dijke, Fangfang Zhou, Long Zhang, 2016, Methods in molecular biology.

Extracellular Vesicles in Cancer Immune Microenvironment and Cancer Immunotherapy

Fangfang Zhou, Xiaoxue Zhou, Feng Xie, 2019, Advanced science.

Cancer Environment Immunotherapy: targeting TGF-β finds its way towards tissue healing and vasculature remodeling

Fangfang Zhou, Long Zhang, Ke Jin, 2021, Signal Transduction and Targeted Therapy.

cGAS-like receptors: new RNA sensors in Drosophila

Fangfang Zhou, Long Zhang, Yao-min Fan, 2021, Signal Transduction and Targeted Therapy.

TRAF 4 Promotes TGF-b Receptor Signaling and Drives Breast Cancer Metastasis

Craig Mickanin, Yihao Li, Peter J. K. Kuppen, 2013 .

TRAF4 mediates activation of TGF-β signaling and is a biomarker for oncogenesis in breast cancer

Fangfang Zhou, Feng Xie, Long Zhang, 2014, Science China Life Sciences.

Biological functions and clinical applications of exosomal long non‐coding RNAs in cancer

Fangfang Zhou, Yali Wang, Mengdi Zhang, 2020, Journal of cellular and molecular medicine.

The Functional Deubiquitinating Enzymes in Control of Innate Antiviral Immunity

Fangfang Zhou, Long Zhang, Zhengkui Zhang, 2020, Advanced science.

Non-coding RNA in thyroid cancer - Functions and mechanisms.

Fangfang Zhou, Long Zhang, Meiyu Fang, 2020, Cancer letters.

Promising Immunotherapies against COVID‐19

Fangfang Zhou, Lili Zhou, Zhenyu Ma, 2021, Advanced therapeutics.

NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell

Guanghui Wang, Ying Su, A. Cheltsov, 2015, Protein & Cell.

The bacteriostatic effect and mechanism of berberine on Methicillin resistant Staphylococcus aureus in vitro

Fangfang Zhou, Lei Wang, Minyi Xu, 2019 .

Suppression of GSK3β by ERK mediates lipopolysaccharide induced cell migration in macrophage through β-catenin signaling

Fangfang Zhou, Long Zhang, Y. Gong, 2012, Protein & Cell.

Bisindoylmaleimide I enhances osteogenic differentiation

Fangfang Zhou, Long Zhang, Huizhe Huang, 2012, Protein & Cell.

LEF-1 activates the transcription of E2F1.

Fangfang Zhou, Long Zhang, Y. Gong, 2008, Biochemical and biophysical research communications.

LEF-1 activates the transcription of E 2 F 1

Fangfang Zhou, Long Zhang, Y. Gong, 2007 .

Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation.

P. Dijke, T. Laar, Fangfang Zhou, 2011 .

Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer.

P. ten Dijke, Fangfang Zhou, Long Zhang, 2013, Trends in biochemical sciences.

Genetic variants in SLC7A7 are associated with risk of glioma in a Chinese population

Q. Lan, Y. Mao, Hongyan Chen, 2013, Experimental biology and medicine.