S. P. Fletcher

发表

Conversion of light into macroscopic helical motion.

J. Cornelissen, N. Katsonis, Supitchaya Iamsaard, 2014, Nature chemistry.

Novel applications of physical autocatalysis

S. P. Fletcher, Andrew J Bissette, 2015, Origins of Life and Evolution of Biospheres.

Formal radical cyclization onto benzene rings: a general method and its use in the synthesis of ent-nocardione A.

S. P. Fletcher, D. Clive, Dazhan Liu, 2004, The Journal of organic chemistry.

Formation of quaternary centres by copper catalysed asymmetric conjugate addition to β-substituted cyclopentenones with the aid of a quantitative structure–selectivity relationship† †Electronic supplementary information (ESI) available. CCDC 1811310–1811312, 1818574 and 1818575. For ESI and crystall

R. Paton, S. P. Fletcher, R. Ardkhean, 2018, Chemical science.

Copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents to cyclic enones to form quaternary centers

S. P. Fletcher, P. Roth, Mireia Sidera, 2013, Nature Protocols.

Oxidation of p-aminophenols and formal radical cyclization onto benzene rings: formation of benzo-fused nitrogen heterocycles.

Jianbiao Peng, S. P. Fletcher, D. Clive, 2005, Organic letters.

Enantioselective Conjugate Addition Catalyzed by a Copper Phosphoramidite Complex: Computational and Experimental Exploration of Asymmetric Induction

Q. Peng, R. Paton, S. P. Fletcher, 2017 .

Simple Azo Dyes Provide Access to Versatile Chiroptical Switches

S. P. Fletcher, E. Anger, 2015 .

Coupled Metabolic Cycles Allow Out‐of‐Equilibrium Autopoietic Vesicle Replication

P. Kukura, S. P. Fletcher, M. Lebedeva, 2020, Angewandte Chemie.

Diverse Cyclopentenes via Enantioselective Cu-Catalyzed Desymmetrization

S. P. Fletcher, Reece Jacques, Robert D. C. Pullin, 2018 .

Novel Disulfides with Antitumour Efficacy and Specificity

L. Penn, Rebecca Griffiths, W. Wong, 2005 .

Barrierless Photoisomerization of 11-cis Retinal Protonated Schiff Base in Solution.

Jong Min Lim, P. Kukura, T. Claridge, 2015, Journal of the American Chemical Society.

Oligomerization Driven by Phase Separation

Ignacio Colomer, S. P. Fletcher, I. Myrgorodska, 2020, ChemSystemsChem.

Catalytic enantioselective synthesis of naturally occurring butenolides via hetero-allylic alkylation and ring closing metathesis.

B. Feringa, A. Minnaard, S. P. Fletcher, 2011, Organic letters.

Fluorinated Azobenzenes for Shape-Persistent Liquid Crystal Polymer Networks.

N. Katsonis, Supitchaya Iamsaard, S. Aßhoff, 2016, Angewandte Chemie.

Building blocks of life: Growing the seeds of homochirality.

S. P. Fletcher, S. Fletcher, 2009, Nature chemistry.

Hydrometallation-asymmetric conjugate addition: application to complex molecule synthesis.

S. P. Fletcher, P. Roth, Rebecca M. Maksymowicz, 2013, Chemical communications.

Controlling axial conformation in 2-arylpyridines and 1-arylisoquinolines: application to the asymmetric synthesis of QUINAP by dynamic thermodynamic resolution.

S. P. Fletcher, J. Clayden, J. McDouall, 2009, Journal of the American Chemical Society.

Highly enantioselective rhodium-catalyzed cross-coupling of boronic acids and racemic allyl halides

S. P. Fletcher, F. W. Goetzke, Jesús González, 2019, Nature Protocols.

Diverse Cyclopentenes via Enantioselective Cu-Catalyzed Desymmetrization

S. P. Fletcher, Reece Jacques, Robert D. C. Pullin, 2018 .

Retooling Asymmetric Conjugate Additions for Sterically Demanding Substrates with an Iterative Data-Driven Approach

R. Paton, S. P. Fletcher, Alexandre V. Brethomé, 2019, ACS catalysis.

Catalytic Asymmetric S uzuki– M iyaura Couplings

S. P. Fletcher, F. W. Goetzke, L. V. Dijk, 2019 .

Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates

S. P. Fletcher, Mireia Sidera, Philipp Schäfer, 2017, Nature Communications.

An autonomously oscillating supramolecular self-replicator

S. P. Fletcher, A. Engwerda, R. Scanes, 2022, Nature Chemistry.

Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides

S. P. Fletcher, Philipp Schäfer, Jesús González, 2018, Organometallics.

8.26 Reduction of Saturated Alkyl Halides to Alkanes

S. P. Fletcher, V. Ziffle, 2014 .

A molecular assembler that produces polymers

S. P. Fletcher, A. Engwerda, S. Fletcher, 2020, Nature Communications.

Acceleration of lipid reproduction by emergence of microscopic motion

N. Katsonis, T. Kudernac, S. P. Fletcher, 2020, Nature Communications.

Dissipative self-assembly, competition and inhibition in a self-reproducing protocell model†

S. P. Fletcher, Elias A J Post, S. Fletcher, 2020, Chemical science.

Potential for minimal self-replicating systems in a dynamic combinatorial library of equilibrating imines

S. P. Fletcher, S. Morrow, Andrew J. Bissette, 2017 .

β-Chloroaldehydes from Trapping Zirconium Enolates Produced in Asymmetric 1,4-Additions.

S. P. Fletcher, Thomas Palacin, J. Wang, 2018, Organic letters.

Dioxomolybdenum(VI) complexes containing 1-alkyl-2-ethyl-3-hydroxy-4-pyridin-4(1H)-ones

S. P. Fletcher, S. Westcott, A. Decken, 2003 .

Rhodium-catalysed asymmetric allylic arylation of racemic halides with arylboronic acids

S. P. Fletcher, Mireia Sidera, S. Fletcher, 2015, Nature Chemistry.

8.32 Hydrogenolysis of Allyl and Benzyl Halides and Related Compounds

S. P. Fletcher, Andrew J. Bissette, S. Fletcher, 2014 .

Mechanisms of autocatalysis.

S. P. Fletcher, Andrew J Bissette, Stephen P Fletcher, 2013, Angewandte Chemie.

Visualization of the spontaneous emergence of a complex, and system

J. Ortega-Arroyo, P. Kukura, S. P. Fletcher, 2017 .

Mechanism of Autocatalysis

S. P. Fletcher, Andrew J. Bissette, S. Fletcher, 2014 .

Asymmetric remote C-H functionalization: Use of internal olefins in tandem hydrometallation – isomerization – asymmetric conjugate addition sequences

S. P. Fletcher, Mireia Sidera, Laura Mola, 2015 .

Systems chemistry: Selecting complex behaviour.

S. P. Fletcher, Andrew J. Bissette, 2015, Nature chemistry.

Enantiomerically enriched tetrahydropyridine allyl chlorides

R. Paton, S. P. Fletcher, Alexandre V. Brethomé, 2019, Chemical Science.

An Asymmetric Suzuki-Miyaura Approach to Prostaglandins: Synthesis of Tafluprost.

S. P. Fletcher, F. W. Goetzke, Roman Kučera, 2020, Organic letters.

Catalytic asymmetric synthesis of carbocyclic C-nucleosides

S. P. Fletcher, Sourabh Mishra, F. Modicom, 2022, Communications Chemistry.

Acyclic quaternary centers from asymmetric conjugate addition of alkylzirconium reagents to linear trisubstituted enones† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc02811j Click here for additional data file.

S. P. Fletcher, Zhenbo Gao, 2016, Chemical science.

Formation of quaternary centers by copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents.

S. P. Fletcher, P. Roth, Mireia Sidera, 2013, Angewandte Chemie.

Synthesis of (+)-nocardione A--use of formal radical cyclization onto a benzene ring.

S. P. Fletcher, D. Clive, 2003, Chemical communications.

Copper-catalyzed asymmetric allylic substitution reactions with organozinc and Grignard reagents

B. Feringa, A. Minnaard, S. P. Fletcher, 2008 .

Preparation of biomimetic photoresponsive polymer springs

Nathalie Katsonis, Federico Lancia, N. Katsonis, 2016, Nature Protocols.

Formal radical cyclization onto benzene rings--a general method proceeding via cross-conjugated dienones.

Mingzhao Zhu, S. P. Fletcher, D. Clive, 2003, Chemical communications.

Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes

S. P. Fletcher, Mireia Sidera, F. W. Goetzke, 2021, Chemical science.

Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles

S. P. Fletcher, Reece Jacques, Robert D. C. Pullin, 2019, Nature Communications.

Construction of β to carbonyl stereogenic centres by asymmetric 1,4-addition of alkylzirconocenes to dienones and ynenones.

S. P. Fletcher, Zhenbo Gao, 2018, Chemical communications.

Asymmetric cross-coupling of alkyl, alkenyl and (hetero)aryl nucleophiles with racemic allyl halides.

S. P. Fletcher, Mireia Sidera, Philipp Schäfer, 2017, Chemical communications.

Asymmetric conjugate addition of alkylzirconium reagents to α,β-unsaturated thioesters: access to fragrances and acyclic stereochemical arrays.

S. P. Fletcher, Zhenbo Gao, 2017, Chemical communications.

Mechanistic Studies on a Cu-Catalyzed Asymmetric Allylic Alkylation with Cyclic Racemic Starting Materials.

E. Rideau, T. Claridge, S. P. Fletcher, 2017, Journal of the American Chemical Society.

Cp2ZrMeCl: A Reagent for Asymmetric Methyl Addition.

S. P. Fletcher, Kilian Garrec, 2016, Organic letters.

Copper-catalysed asymmetric allylic alkylation of alkylzirconocenes to racemic 3,6-dihydro-2H-pyrans

E. Rideau, S. P. Fletcher, 2015, Beilstein journal of organic chemistry.

Asymmetric conjugate additions and allylic alkylations using nucleophiles generated by hydro- or carbometallation.

S. P. Fletcher, Rebecca M. Maksymowicz, Andrew J. Bissette, 2015, Chemistry.

Enantioselective copper(I)-phosphoramidite catalyzed addition of alkylzirconium species to acyclic enones.

S. P. Fletcher, P. Roth, 2015, Organic letters.

Non-stabilized nucleophiles in Cu-catalysed dynamic kinetic asymmetric allylic alkylation

E. Rideau, S. P. Fletcher, Hengzhi You, 2015, Nature.

Asymmetric conjugate addition of alkylzirconium reagents to α,β-unsaturated lactones.

S. P. Fletcher, P. Roth, Rebecca M. Maksymowicz, 2014, Organic letters.

Catalytic asymmetric carbon–carbon bond formation using alkenes as alkylmetal equivalents

S. P. Fletcher, P. Roth, Rebecca M. Maksymowicz, 2012, Nature Chemistry.

Current methods for asymmetric halogenation of olefins.

S. P. Fletcher, Alejandro Castellanos, S. Fletcher, 2011, Chemistry.

Catalytic asymmetric synthesis of acyclic arrays by tandem 1,4-addition-aldol reactions.

B. Feringa, S. P. Fletcher, Bjorn ter Horst, 2006, Journal of the American Chemical Society.

Cu-catalyzed asymmetric addition of sp²-hybridized zirconium nucleophiles to racemic allyl bromides.

S. P. Fletcher, Mireia Sidera, S. Fletcher, 2015, Chemical communications.

Synthesis of diverse 2,3-dihydroindoles, 1,2,3,4-tetrahydroquinolines, and benzo-fused azepines by formal radical cyclization onto aromatic rings.

Jianbiao Peng, S. P. Fletcher, D. Clive, 2008, The Journal of organic chemistry.

Catalytic asymmetric synthesis of geminal-dicarboxylates† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01786g

S. P. Fletcher, N. Mistry, S. Fletcher, 2018, Chemical science.

A catalytic asymmetric cross-coupling approach to the synthesis of cyclobutanes

S. P. Fletcher, F. W. Goetzke, Lucy van Dijk, 2021, Nature Chemistry.

A General Catalyst Controlled Route to Prostaglandin F2α

S. P. Fletcher, Sourabh Mishra, Laura Cunningham, 2022, Organic letters.

Copper catalyzed asymmetric synthesis of chiral allylic esters.

B. Feringa, S. P. Fletcher, Koen Geurts, 2006, Journal of the American Chemical Society.

Synthesis of (+)-Nocardione A — Use of Formal Radical Cyclization onto a Benzene Ring.

S. P. Fletcher, D. Clive, 2004 .

Copper‐Catalyzed Asymmetric Allylic Substitution Reactions with Organozinc and Grignard Reagents

B. Feringa, A. Minnaard, S. P. Fletcher, 2008 .

Hindered diarylether and diarylsulfone bisphosphine ligands: Atropisomerism and palladium complexes

S. P. Fletcher, J. Clayden, J. Senior, 2010 .

Synthesis of the bicyclic dienone core of the antitumor agent ottelione B.

S. P. Fletcher, D. Clive, S. Fletcher, 2002, Chemical communications.

Ligand Design for Asymmetric Catalysis: Combining Mechanistic and Chemoinformatics Approaches

Robert S. Paton, Ruchuta Ardkhean, Stephen P. Fletcher, 2020 .

Mechanistic investigation of Rh(I)-catalyzed asymmetric Suzuki-Miyaura coupling with racemic allyl halides

R. Paton, T. Claridge, S. P. Fletcher, 2019 .

Synthesis of enantiomerically enriched (R)-13C-labelled 2-aminoisobutyric acid (Aib) by conformational memory in the alkylation of a derivative of L-alanine

S. P. Fletcher, Jordi Solà, J. Clayden, 2011, Beilstein journal of organic chemistry.

Molecular machines for catalysis

Stephen P. Fletcher, Lucy van Dijk, Michael J. Tilby, 2018 .

Desymmetrization of meso-bisphosphates via rhodium catalyzed asymmetric allylic arylation

S. P. Fletcher, Reece Jacques, Robert D. C. Pullin, 2019, Tetrahedron.

Nanometer-range communication of stereochemical information by reversible switching of molecular helicity.

S. P. Fletcher, Jordi Solà, J. Clayden, 2010, Angewandte Chemie.

An astrophysically-relevant mechanism for amino acid enantiomer enrichment.

B. Feringa, S. P. Fletcher, R. Jagt, 2007, Chemical communications.

Transmission of chirality through space and across length scales.

S. P. Fletcher, Sarah M. Morrow, Andrew J. Bissette, 2017, Nature nanotechnology.

A Reversible, Unidirectional Molecular Rotary Motor Driven by Chemical Energy

Michael M. Pollard, Frédéric Dumur, Ben L Feringa, 2005, Science.

A transient self-assembling self-replicator

Ignacio Colomer, S. P. Fletcher, S. Morrow, 2018, Nature Communications.

High‐Power Actuation from Molecular Photoswitches in Enantiomerically Paired Soft Springs

Benjamin Matt, Nathalie Katsonis, Tibor Kudernac, 2017, Angewandte Chemie.

Scale-Up of a Rh-Catalyzed Asymmetric sp3–sp2 Suzuki–Miyaura-Type Reaction

Mireia Sidera Portela, S. P. Fletcher, Laura Cunningham, 2022, Organic process research & development.

Living and immortal polymerization of seven and six membered lactones to high molecular weights with aluminum salen and salan catalysts

S. P. Fletcher, J. P. Macdonald, Mireia Sidera, 2016 .

Synthetic control of retinal photochemistry and photophysics in solution.

P. Kukura, T. Claridge, S. P. Fletcher, 2014, Journal of the American Chemical Society.

Synthesis of the Taxol Core via Catalytic Asymmetric 1,4-Addition of an Alkylzirconium Nucleophile.

S. P. Fletcher, J. Wang, S. Fletcher, 2020, Organic letters.

A Convenient Catalytic Asymmetric Conjugate Addition Reaction to Enones Using Alkylzirconium Reagents.

S. P. Fletcher, P. Roth, Mireia Sidera, 2014 .

An alternative synthesis of the breast cancer drug fulvestrant (Faslodex®): catalyst control over C-C bond formation.

S. P. Fletcher, Diego Caprioglio, S. Fletcher, 2015, Chemical communications.

A convenient catalytic asymmetric conjugate addition reaction to enones using alkylzirconium reagents

S. P. Fletcher, P. Roth, Mireia Sidera, 2013 .

Backbone modification of retinal induces protein-like excited state dynamics in solution.

P. Kukura, S. P. Fletcher, M. Liebel, 2012, Journal of the American Chemical Society.

Conformational Effects on Physical-Organic Descriptors: The Case of Sterimol Steric Parameters

R. Paton, S. P. Fletcher, Alexandre V. Brethomé, 2018, ACS Catalysis.

Structure‐function studies for in vitro chemical inhibition of Fcγ receptor–mediated phagocytosis

R. Langler, S. P. Fletcher, D. Branch, 2007, Transfusion.

Emergence and Rearrangement of Dynamic Supramolecular Aggregates Visualized by Interferometric Scattering Microscopy

P. Kukura, S. P. Fletcher, M. Lebedeva, 2020, ACS nano.

The S2 Oxygen Atoms Are Essential for the Pronounced Fungitoxicity of the Sulfur-Rich Natural Product, Dysoxysulfone

E. O'brien, S. Bewick, R. Langler, 2005 .

Selection between Competing Self-Reproducing Lipids: Succession and Dynamic Activation

S. P. Fletcher, R. Scanes, Michael G. Howlett, 2021, JACS Au.

Physical autocatalysis driven by a bond-forming thiol–ene reaction

S. P. Fletcher, B. Odell, Andrew J. Bissette, 2014, Nature Communications.

A chemically fuelled self-replicator

Ignacio Colomer, S. P. Fletcher, S. Morrow, 2019, Nature Communications.

Self-reproducing micelles coupled to a secondary catalyst.

S. P. Fletcher, Elias A J Post, Andrew J. Bissette, 2018, Chemical communications.

Visualization of the spontaneous emergence of a complex, dynamic, and autocatalytic system

J. Ortega-Arroyo, P. Kukura, S. P. Fletcher, 2016, Proceedings of the National Academy of Sciences.

Formal Radical Cyclization onto Benzene Rings: A General Method and Its Use in the Synthesis of ent‐Nocardione A.

S. P. Fletcher, D. Clive, Dazhan Liu, 2004 .