U. Schindler

发表

RNP-T, a ribonucleoprotein from Arabidopsis thaliana, contains two RNP-80 motifs and a novel acidic repeat arranged in an α-helix conformation

D. Bar-Zvi, A. Cashmore, T. Shagan, 1992, Plant Molecular Biology.

DNA Binding Specificity of Different STAT Proteins

P. Bucher, C. Horvath, U. Schindler, 2001, The Journal of Biological Chemistry.

Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression

V. Baichwal, U. Schindler, 1994, Molecular and cellular biology.

DNA Binding Site Selection of Dimeric and Tetrameric Stat5 Proteins Reveals a Large Repertoire of Divergent Tetrameric Stat5a Binding Sites

S. Moro, W. Leonard, S. John, 2000, Molecular and Cellular Biology.

Heterodimerization between light‐regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins.

J R Ecker, J. Ecker, A. Cashmore, 1992, The EMBO journal.

DNA binding site preferences and transcriptional activation properties of the Arabidopsis transcription factor GBF1.

W. Terzaghi, T. Kadesch, A. Cashmore, 1992, The EMBO journal.

Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M.

L. Naeger, M. Kaplan, T. Hoey, 2002, Immunity.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

DNA binding activity of the Arabidopsis G-box binding factor GBF1 is stimulated by phosphorylation by casein kinase II from broccoli.

L. Klimczak, A. Cashmore, U. Schindler, 1992, The Plant cell.

Discovery of Potent and Selective PI3Kγ Inhibitors.

N. Walker, U. Schindler, J. Powers, 2020, Journal of medicinal chemistry.

HAT3.1, a novel Arabidopsis homeodomain protein containing a conserved cysteine-rich region.

A. Cashmore, U. Schindler, H. Beckmann, 1993, The Plant journal : for cell and molecular biology.

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

M. Kaplan, U. Schindler, M. Grusby, 1996, Immunity.

Stat6 inhibits human interleukin-4 promoter activity in T cells.

V. Casolaro, S. Georas, J. Cumberland, 1998, Blood.

IL‐4 Signaling Mechanisms in Inflammatory Bowel Disease Mononuclear Phagocytes

S. Nikolaus, U. Schindler, T. Heinig, 1996, Inflammatory bowel diseases.

Cutting Edge: Chandra, a Novel Four-Transmembrane Domain Protein Differentially Expressed in Helper Type 1 Lymphocytes

G. Schaefer, U. Schindler, C. Venkataraman, 2000, The Journal of Immunology.

Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism.

V. Casolaro, S. Georas, R. Schleimer, 2001, American journal of respiratory cell and molecular biology.

Molecular Mechanisms of Repression of Eotaxin Expression with Fluticasone Propionate in Airway Epithelial Cells

M. Kawaguchi, M. Adachi, Shintaro Suzuki, 2004, International Archives of Allergy and Immunology.

Distinct Effects in T and B Cells Vivo Alters Lymphocyte Homeostasis with Expression of a Constitutively Active Stat6 In

M. Kaplan, U. Schindler, Heather A. Bruns, 2003 .

Repression of IL-4-induced gene expression by IFN-gamma requires Stat1 activation.

H. Mano, U. Schindler, C. Venkataraman, 1999, Journal of immunology.

Promoter Mediated by Stat6 and C/EBP e Synergistic Activation of the Germline

U. Schindler, M. Kurama, T. Mikita, 1998 .

Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ).

N. Walker, U. Schindler, J. Powers, 2021, Journal of medicinal chemistry.

Synergistic activation of the germline epsilon promoter mediated by Stat6 and C/EBP beta.

U. Schindler, M. Kurama, T. Mikita, 1998, Journal of immunology.

TGA1 and G-box binding factors: two distinct classes of Arabidopsis leucine zipper proteins compete for the G-box-like element TGACGTGG.

A. Cashmore, U. Schindler, H. Beckmann, 1992, The Plant cell.

The G-box: a ubiquitous regulatory DNA element in plants bound by the GBF family of bZIP proteins.

A. Cashmore, U. Schindler, A. Menkens, 1995, Trends in biochemical sciences.

Stat Proteins Control Lymphocyte Proliferation by Regulating p27Kip1 Expression

M. Kaplan, C. Daniel, U. Schindler, 1998, Molecular and Cellular Biology.

Differential Roles of C-terminal Activation Motifs in the Establishment of Stat6 Transcriptional Specificity*

M. Boothby, S. Goenka, U. Schindler, 2003, Journal of Biological Chemistry.

Paired Stat6 C-terminal transcription activation domains required both for inhibition of an IFN-responsive promoter and trans-activation.

M. Boothby, J. Youn, L. Yu-Lee, 1999, Journal of immunology.

Mutational Analysis of the STAT6 SH2 Domain*

C. Daniel, U. Schindler, T. Mikita, 1998, The Journal of Biological Chemistry.

Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors.

N. Walker, U. Schindler, J. Powers, 2020, ACS medicinal chemistry letters.

Identification and purification of human Stat proteins activated in response to interleukin-2.

S. McKnight, W. Henzel, S. Wong, 1995, Immunity.

A Gain-of-function Mutation in STAT6*

U. Schindler, A. Salvekar, Carla Daniel, 2000, The Journal of Biological Chemistry.

An interleukin-4-induced transcription factor: IL-4 Stat.

S. McKnight, W. Henzel, U. Schindler, 1994, Science.

Components of a Stat recognition code: evidence for two layers of molecular selectivity.

S. McKnight, M. Rothe, U. Schindler, 1995, Immunity.

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.

B. Groner, Y. Minami, F. Gouilleux, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Expression of a Constitutively Active Stat6 In Vivo Alters Lymphocyte Homeostasis with Distinct Effects in T and B Cells1

M. Kaplan, U. Schindler, Heather A. Bruns, 2003, The Journal of Immunology.

Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression.

U. Schindler, H. Dickensheets, R. Donnelly, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Stat6 inhibits human interleukin-4 promoter activity in T cells

V. Casolaro, S. Georas, J. Cumberland, 1998 .

Differentiation of T‐helper lymphocytes: selective regulation by members of the STAT family of transcription factors

S. McKnight, T. Hoey, U. Schindler, 1996, Genes to cells : devoted to molecular & cellular mechanisms.

Cutting Edge: FISP (IL-4-Induced Secreted Protein), a Novel Cytokine-Like Molecule Secreted by Th2 Cells1

U. Schindler, C. Venkataraman, G. Schaefer, 2001, The Journal of Immunology.

Impact of the selective A2AR and A2BR dual antagonist AB928/etrumadenant on CAR T cell function

S. Endres, U. Schindler, S. Kobold, 2022, British Journal of Cancer.

Requirements for interleukin-4-induced gene expression and functional characterization of Stat6

U. Schindler, D. Campbell, K. Williamson, 1996, Molecular and cellular biology.

Interaction of STAT5 Dimers on Two Low Affinity Binding Sites Mediates Interleukin 2 (IL-2) Stimulation of IL-2 Receptor α Gene Transcription*

U. Schindler, P. Reichenbach, M. Nabholz, 1997, The Journal of Biological Chemistry.

Repression of IL-4-Induced Gene Expression by IFN-γ Requires Stat1 Activation

H. Mano, U. Schindler, S. Leung, 1999, The Journal of Immunology.

Activation Trans-and Inhibition of an IFN-Responsive Promoter Activation Domains Required Both for Paired Stat 6 C-Terminal Transcription

M. Boothby, L. Yu-Lee, S. Goenka, 1999 .

STAT structure and function in signaling.

T. Hoey, U. Schindler, Timothy Hoey, 1998, Current opinion in genetics & development.

Photoregulated gene expression may involve ubiquitous DNA binding proteins.

A. Cashmore, U. Schindler, U Schindler, 1990, The EMBO journal.

Synergistic Activation of the Germline ε Promoter Mediated by Stat6 and C/EBPβ

U. Schindler, Thomas Mikita, Masae Kurama, 1998, The Journal of Immunology.

A high-throughput STAT binding assay using fluorescence polarization.

U. Schindler, M. Brasseur, P. Wu, 1997, Analytical biochemistry.

Abstracts from the 4th ImmunoTherapy of Cancer Conference

R. Rees, F. Regnier, A. Trautmann, 2017, Journal of Immunotherapy for Cancer.

Nuclear factors binding to the extensin promoter exhibit differential activity in carrot protoplasts and cells

J. Peretó, A. Granell, A. Cashmore, 1992, Plant Molecular Biology.

Abstract A162: AB928, a dual antagonist of the A2aR and A2bR adenosine receptors, relieves adenosine-mediated immune suppression

F. Soriano, U. Schindler, J. Powers, 2019, Maintenance of Immune Balance: Effects of Targeted and Immune Therapies.

Abstract 5556: Combining adenosine receptor inhibition with AB928 and chemotherapy results in greater immune activation and tumor control

F. Soriano, U. Schindler, J. Powers, 2018, Clinical Research (Excluding Clinical Trials).

The plant G box promoter sequence activates transcription in Saccharomyces cerevisiae and is bound in vitro by a yeast activity similar to GBF, the plant G box binding factor.

U. Schindler, A. Batschauer, A. R. Cashmore, 1990, The EMBO journal.

An Arabidopsis Thaliana Leucine Zipper Protein that Binds to G-Box Promoter Sequences

J. Ecker, A. Cashmore, U. Schindler, 1991 .

Abstract 1756: Discovery and characterization of AB680, a potent and selective small-molecule CD73 inhibitor for cancer immunotherapy

U. Schindler, Lixia Jin, Ada Chen, 2018, Immunology.

Abstract 710: CD73 inhibitors (CD73i) reverse the AMP/adenosine-mediated impairment of immune effector cell activation by immune checkpoint inhibitors (ICI)

A. Becker, U. Schindler, J. Powers, 2018, Immunology.

AB680, a potent and selective CD73 small molecule inhibitor, reverses the AMP/adenosine-mediated impairment of immune effector cell activation by immune checkpoint inhibitors

A. Becker, U. Schindler, J. Powers, 2018 .

DNA Binding Site Selection of Dimeric and Tetrameric Stat5 Proteins Reveals a Large Repertoire of Divergent Tetrameric Stat5a Binding Sites

S. Moro, W. Leonard, S. John, 2000, Molecular and Cellular Biology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

Inducible Plant Proteins: GBF-1, GBF-2 and GBF-3: three Arabidopsis b-Zip proteins that interact with the light-regulated rbcS-1A promoter

A. Cashmore, J. Wray, U. Schindler, 1992 .