D. Entwistle

发表

Engineering biosynthetic enzymes for industrial natural product synthesis.

S. Galanie, D. Entwistle, J. Lalonde, 2020, Natural product reports.

Inhalation by design: dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD.

M. Bunnage, David A. Price, M. Trevethick, 2011, Bioorganic & medicinal chemistry letters.

Optimized glucuronidation of dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD

M. Bunnage, David A. Price, M. Trevethick, 2011 .

Saturated and unsaturated hydrocarbons

D. Entwistle, 1997 .

Replacing dichloroethane as a solvent for rhodium-catalysed intermolecular alkyne hydroacylation reactions: the utility of propylene carbonate

Paul M. Ylioja, M. Willis, D. Entwistle, 2011 .

Inhalation by design: novel tertiary amine muscarinic M₃ receptor antagonists with slow off-rate binding kinetics for inhaled once-daily treatment of chronic obstructive pulmonary disease.

M. Bunnage, David A. Price, A. Wood, 2011, Journal of medicinal chemistry.

Dispiroketals in synthesis (part 19)1: Dispiroketals as enantioselective and regioselective protective agents for symmetric cyclic and acyclic polyols.

S. Ley, D. Entwistle, P. Edwards, 1995 .

Dispiroketals in synthesis (Part 11): Concomitant enantioselective and regioselective protection of 2,5- dibenzoyl-myo-inositol

S. Ley, D. Entwistle, P. Edwards, 1994 .

Baeyer-Villiger Monooxygenase-Mediated Synthesis of Esomeprazole As an Alternative for Kagan Sulfoxidation.

S. Muley, D. Entwistle, Jovana Nazor, 2018, The Journal of organic chemistry.

Engineering an Amine Transaminase for the Efficient Production of a Chiral Sacubitril Precursor

C. Ching, S. Novick, N. Dellas, 2021 .

An alkyne hydroacylation route to highly substituted furans.

M. Willis, D. Entwistle, Philip Lenden, 2011, Angewandte Chemie.

Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited

John D. Hayler, Stefan G. Koenig, Peter J. Dunn, 2018 .

Development of a Scaleable Synthesis of a Geminal Dimethyl Tertiary Amine as an Inhaled Muscarinic Antagonist for the Treatment of COPD

D. Entwistle, P. Glossop, Barry. R. Dillon, 2012 .

Modern Methods of Monosaccharide Synthesis from Non-Carbohydrate Sources.

T. Hudlický, D. Entwistle, K. Pitzer, 1996, Chemical reviews.

Saturated and unsaturated hydrocarbons

D. Entwistle, 2010 .

SYNTHESIS OF PSEUDOSUGARS FROM MICROBIAL METABOLITES

T. Hudlický, D. Entwistle, 1995 .

Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium

E. Darzi, D. Entwistle, M. Giroud, 2019, Communications Chemistry.

Modern Methods of Monosaccharide Synthesis from Non-Carbohydrate Sources

T. Hudlický, D. Entwistle, K. Pitzer, 1996 .

Development of a Practical, Biocatalytic Reduction for the Manufacture of (S)-Licarbazepine Using an Evolved Ketoreductase

G. Huisman, Raquel Keledjian, D. Entwistle, 2014 .

Route Selection and Process Development of a Multikilogram Route to the Inhaled A2a Agonist UK-432,097

D. Entwistle, J. D. Smith, Christopher P. Ashcroft, 2012 .

Dispiroketals in Synthesis. Part 19. Dispiroketals as Enantioselective and Regioselective Protective Agents for Symmetric Cyclic and Acyclic Polyols.

S. Ley, D. Entwistle, P. Edwards, 1996 .

Dispiroketals in synthesis (Part 17): Regioselective protection of D-glucopyranoside D-galactopyranoside and D-mannopyranoside substrates.

S. Ley, D. Entwistle, P. Edwards, 1994 .

A Convenient Synthesis of Masked β-Ketoaldehydes by the Controlled Addition of Nucleophiles to (Trimethylsilyl)ethynyl Ketones

S. Bromidge, D. Entwistle, J. Goldstein, 1993 .

Dispiroketals in synthesis (part 8): Regioselective protection of D-glucopyranose substrates

S. Ley, D. Entwistle, G. Visentin, 1994 .

Dispiroketals in synthesis (part 4): Enantioselective desymmetrization of glycerol using a c2-symmetric disubstituted bis-dihydropyran.

S. Ley, D. Entwistle, Martin Woods, 1993 .

Toluene-Dioxygenase-Mediated cis-Dihydroxylation of Aromatics in Enantioselective Synthesis. Iterative Glycoconjugate CouplingStrategy and Combinatorial Design for the Synthesis of Oligomers of nor-Saccharides,Inositols and Pseudosugars with Interesting Molecular Properties

Tomas Hudlicky, Rakesh Maurya, T. Hudlický, 1996 .

Toluene‐Dioxygenase‐Mediated cis‐Dihydroxylation of Aromatics in Enantioselective Synthesis. Iterative Glycoconjugate Coupling Strategy and Combinatorial Design for the Synthesis of Oligomers of nor‐ Saccharides, Inositols and Pseudosugars with Interesting Molecular Properties.

Tomas Hudlicky, Rakesh Maurya, T. Hudlický, 1996 .

Total synthesis of the virginiamycin antibiotic 14,15-anhydropristinamycin IIB

J. Montgomery, D. Entwistle, G. Pattenden, 1996 .

Case Studies Illustrating a Science and Risk-Based Approach to Ensuring Drug Quality When Using Enzymes in the Manufacture of Active Pharmaceuticals Ingredients for Oral Dosage Form

Timothy J. N. Watson, A. Wells, A. Goswami, 2016 .