M. Clastre

发表

De novo production of the plant-derived alkaloid strictosidine in yeast

S. O’Connor, V. Courdavault, Stephanie Brown, 2015, Proceedings of the National Academy of Sciences.

Cloning and expression of cDNAs encoding two enzymes of the MEP pathway in Catharanthus roseus.

M. Clastre, B. Veau, M. Courtois, 2000, Biochimica et biophysica acta.

Characterization of the plastidial geraniol synthase from Madagascar periwinkle which initiates the monoterpenoid branch of the alkaloid pathway in internal phloem associated parenchyma.

J. Memelink, A. Simkin, N. Papon, 2013, Phytochemistry.

ZCT1 and ZCT2 transcription factors repress the activity of a gene promoter from the methyl erythritol phosphate pathway in Madagascar periwinkle cells.

C. Gaillard, G. Glevarec, R. Atanassova, 2014, Journal of plant physiology.

Class II Cytochrome P450 Reductase Governs the Biosynthesis of Alkaloids1

S. O’Connor, G. Glevarec, Franziska Kellner, 2016, Plant Physiology.

The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia: presence and sensitivity to fosmidomycin.

M. Clastre, F. Laurent, M. Rideau, 2007, Experimental parasitology.

Candida guilliermondii: biotechnological applications, perspectives for biological control, emerging clinical importance and recent advances in genetics

A. Simkin, N. Papon, V. Courdavault, 2013, Current Genetics.

[Yeasts from the CTG clade (Candida clade): Biology, impact in human health, and biotechnological applications].

N. Papon, V. Courdavault, M. Clastre, 2018, Journal de mycologie medicale.

Mechanical stress rapidly induces E-resveratrol and E-piceatannol biosynthesis in grape canes stored as a freshly-pruned byproduct.

S. Besseau, N. Papon, V. Courdavault, 2018, Food chemistry.

Biosynthetic origin of E-resveratrol accumulation in grape canes during postharvest storage.

G. Glevarec, A. Simkin, S. Besseau, 2015, Journal of agricultural and food chemistry.

Deciphering the Evolution, Cell Biology and Regulation of Monoterpene Indole Alkaloids

G. Glevarec, S. Besseau, N. Papon, 2013 .

Hybrid histidine kinases in pathogenic fungi

J. Latgé, A. Mondal, N. Papon, 2015, Molecular microbiology.

CHASE-Containing Histidine Kinase Receptors in Apple Tree: From a Common Receptor Structure to Divergent Cytokinin Binding Properties and Specific Functions

D. Giron, G. Glevarec, S. Besseau, 2017, Front. Plant Sci..

In planta validation of HK1 homodimerization and recruitment of preferential HPt downstream partners involved in poplar multistep phosphorelay systems

D. Morabito, G. Scippa, F. Brignolas, 2013 .

Prenylated Proteins Are Required for Methyl-Jasmonate-Induced Monoterpenoid Indole Alkaloids Biosynthesis in Catharanthus roseus

A. Simkin, V. Courdavault, M. Clastre, 2012 .

Composition and Tissue-Specific Distribution of Stilbenoids in Grape Canes Are Affected by Downy Mildew Pressure in the Vineyard.

A. Simkin, S. Besseau, N. Papon, 2015, Journal of agricultural and food chemistry.

Optimization of Tabersonine Methoxylation to Increase Vindoline Precursor Synthesis in Yeast Cell Factories

N. Kulagina, S. Besseau, N. Papon, 2021, Molecules.

The Identification of Phytohormone Receptor Homologs in Early Diverging Fungi Suggests a Role for Plant Sensing in Land Colonization by Fungi

J. Latgé, F. Martin, T. James, 2017, mBio.

A standardized toolkit for genetic engineering of CTG clade yeasts.

C. d’Enfert, C. Rosa, S. Droby, 2018, Journal of microbiological methods.

A new series of vectors for constitutive, inducible or repressible gene expression in Candida guilliermondii.

G. Glevarec, A. Simkin, N. Papon, 2014, Journal of biotechnology.

Subcellular localization of the histidine kinase receptors Sln1p, Nik1p and Chk1p in the yeast CTG clade species Candida guilliermondii.

G. Glevarec, A. Simkin, S. Besseau, 2014, Fungal genetics and biology : FG & B.

Transformation of Candida guilliermondii wild-type strains using the Staphylococcus aureus MRSA 252 ble gene as a phleomycin-resistant marker.

A. Simkin, N. Papon, V. Courdavault, 2013, FEMS yeast research.

Optimization of the URA-blaster disruption system in Candida guilliermondii: efficient gene targeting using the URA3 marker.

A. Simkin, N. Papon, V. Courdavault, 2012, Journal of microbiological methods.

A TRP5/5-fluoroanthranilic acid counter-selection system for gene disruption in Candida guilliermondii

A. Simkin, S. Besseau, N. Papon, 2012, Current Genetics.

Deus ex Candida genetics: overcoming the hurdles for the development of a molecular toolbox in the CTG clade.

A. Simkin, N. Papon, V. Courdavault, 2012, Microbiology.

Fluorescent protein fusions in Candida guilliermondii.

A. Simkin, N. Papon, V. Courdavault, 2011, Fungal genetics and biology : FG & B.

Drug-resistant cassettes for the efficient transformation of Candida guilliermondii wild-type strains.

A. Simkin, N. Papon, V. Courdavault, 2011, FEMS yeast research.

Development of a URA5 integrative cassette for gene disruption in the Candida guilliermondii ATCC 6260 strain.

A. Simkin, N. Papon, M. Clastre, 2011, Journal of microbiological methods.

Uptake of isopentenyl diphosphate by plastids isolated from Vitis vinifera L. cell suspensions

M. Clastre, G. Marigo, E. Soler, 1993, Planta.

Group X hybrid histidine kinase Chk1 is dispensable for stress adaptation, host-pathogen interactions and virulence in the opportunistic yeast Candida guilliermondii.

H. Mora-Montes, N. Papon, V. Courdavault, 2017, Research in microbiology.

Purification and Characterization of Geranyl Diphosphate Synthase from Vitis vinifera L. cv Muscat de Frontignan Cell Cultures

M. Clastre, G. Feron, E. Soler, 1993, Plant physiology.

Prenyltransferase compartmentation in cells of Vitis vinifera cultivated in vitro

M. Clastre, G. Feron, C. Ambid, 1990, FEBS letters.

Characterization and subcellular localization of geranylgeranyl diphosphate synthase from Catharanthus roseus

S. Bouzid, A. Simkin, N. Papon, 2011, Molecular Biology Reports.

Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta

S. Bouzid, A. Simkin, N. Papon, 2011, Planta.

Purification, molecular cloning, and cell-specific gene expression of the alkaloid-accumulation associated protein CrPS in Catharanthus roseus.

J. Aguirreolea, M. Clastre, V. Burlat, 2005, Journal of experimental botany.

Evidence for a geranyl-diphosphate synthase located within the plastids of Vitis vinifera L. cultivated in vitro

M. Clastre, G. Feron, E. Soler, 1992, Planta.

UPLC-HRMS Analysis Revealed the Differential Accumulation of Antioxidant and Anti-Aging Lignans and Neolignans in In Vitro Cultures of Linum usitatissimum L

Duangjai Tungmunnithum, M. Clastre, B. Abbasi, 2020, Frontiers in Plant Science.

1-Deoxy-D-xylulose 5-phosphate synthase from periwinkle: cDNA identification and induced gene expression in terpenoid indole alkaloid-producing cells.

M. Clastre, A. Oudin, J. Chénieux, 2000 .

Identifying Missing Biosynthesis Enzymes of Plant Natural Products.

S. O’Connor, N. Papon, V. Courdavault, 2020, Trends in pharmacological sciences.

Candida guilliermondii: biotechnological applications, perspectives for biological control, emerging clinical importance and recent advances in genetics

A. Simkin, N. Papon, V. Courdavault, 2013, Current Genetics.

Purification and Characterization of Cinnamoyl-Coenzyme A:NADP Oxidoreductase in Eucalyptus gunnii

A. Boudet, D. Goffner, M. Clastre, 1994, Plant physiology.

Prequels to Synthetic Biology: From Candidate Gene Identification and Validation to Enzyme Subcellular Localization in Plant and Yeast Cells.

G. Glevarec, S. Besseau, N. Papon, 2016, Methods in enzymology.

Efficient gene targeting in a Candida guilliermondii non-homologous end-joining pathway-deficient strain

A. Simkin, N. Papon, V. Courdavault, 2013, Biotechnology Letters.

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

S. O’Connor, E. Tatsis, Thu-Thuy T. Dang, 2017, Nature Communications.

A Pair of Tabersonine 16-Hydroxylases Initiates the Synthesis of Vindoline in an Organ-Dependent Manner in Catharanthus roseus1[C][W]

F. Geu-Flores, D. Werck-Reichhart, B. Schneider, 2013, Plant Physiology.

Ranking genome-wide correlation measurements improves microarray and RNA-seq based global and targeted co-expression networks

G. Glevarec, S. Besseau, V. Courdavault, 2018, Scientific Reports.

Genetic Manipulation of Meyerozyma guilliermondii

N. Papon, V. Courdavault, M. Clastre, 2015 .

Emerging and Emerged Pathogenic Candida Species: Beyond the Candida albicans Paradigm

Nicolas Papon, Vincent Courdavault, Richard J. Bennett, 2013, PLoS pathogens.

A single gene encodes isopentenyl diphosphate isomerase isoforms targeted to plastids, mitochondria and peroxisomes in Catharanthus roseus

G. Glevarec, M. Rodríguez-Concepcíon, N. Papon, 2012, Plant Molecular Biology.

Antifungal activity of resveratrol derivatives against Candida species.

S. Besseau, N. Papon, V. Courdavault, 2014, Journal of natural products.

A look inside an alkaloid multisite plant: the Catharanthus logistics.

N. Papon, V. Courdavault, M. Clastre, 2014, Current opinion in plant biology.

Field-Based Metabolomics of Vitis vinifera L. Stems Provides New Insights for Genotype Discrimination and Polyphenol Metabolism Structuring

S. Besseau, V. Courdavault, M. Clastre, 2018, Front. Plant Sci..

Enhanced bioproduction of anticancer precursor vindoline by yeast cell factories

N. Kulagina, S. Besseau, N. Papon, 2021, Microbial biotechnology.

An additional Meyerozyma guilliermondii IMH3 gene confers mycophenolic acid resistance in fungal CTG clade species.

G. Glevarec, S. Besseau, N. Papon, 2016, FEMS yeast research.

Alternative splicing creates a pseudo-strictosidine β-d-glucosidase modulating alkaloid synthesis in Catharanthus roseus.

S. O’Connor, Dinesh A Nagegowda, N. Kulagina, 2020, Plant physiology.

Folivory elicits a strong defense reaction in Catharanthus roseus: metabolomic and transcriptomic analyses reveal distinct local and systemic responses

S. Maury, E. Huguet, S. O’Connor, 2017, Scientific Reports.

Phytochemical genomics of the Madagascar periwinkle: Unravelling the last twists of the alkaloid engine.

G. Glevarec, S. Besseau, N. Papon, 2015, Phytochemistry.

The iridoid pathway in Catharanthus roseus alkaloid biosynthesis

M. Clastre, M. Courtois, A. Oudin, 2007, Phytochemistry Reviews.

Induction of a novel cytochrome P450 (CYP96 family) in periwinkle (Catharanthus roseus) cells induced for terpenoid indole alkaloid production

M. Clastre, A. Oudin, J. Chénieux, 1999 .

Synthetic Biology in the Candida (CTG) Clade

S. Besseau, N. Papon, V. Courdavault, 2022, Synthetic Biology of Yeasts.

Improved gene co-expression network quality through expression dataset down-sampling and network aggregation

Nicolas Papon, Vincent Courdavault, Franziska Liesecke, 2019, Scientific Reports.

Characterization of an autonomously replicating sequence in Candida guilliermondii.

Nicolas Papon, Vincent Courdavault, Sébastien Besseau, 2013, Microbiological research.

The electronic plant gene register

D. Blanchard, J. Christie, T. Kiyosue, 1995, Plant physiology.

Setting-up a fast and reliable cytokinin biosensor based on a plant histidine kinase receptor expressed in Saccharomyces cerevisiae.

A. Degrave, G. Glevarec, S. Besseau, 2019, Journal of biotechnology.

Diversity and Evolution of Sensor Histidine Kinases in Eukaryotes

J. Cock, P. Schaap, N. Papon, 2018, Genome biology and evolution.

Illuminating Fungal Infections with Bioluminescence

N. Papon, V. Courdavault, M. Clastre, 2014, PLoS pathogens.

Ranking genome-wide correlation measurements improves microarray and RNA-seq based global and targeted co-expression networks

G. Glevarec, S. Besseau, V. Courdavault, 2018, bioRxiv.

Disruption of Protein Mannosylation Affects Candida guilliermondii Cell Wall, Immune Sensing, and Virulence

A. Gácser, Mercedes G. López, H. Mora-Montes, 2016, Front. Microbiol..

Several of these metabolites , such as the analgesic morphine , the antitussive codeine from

N. Kulagina, S. Besseau, N. Papon, 2021 .

Characterization of a second secologanin synthase isoform producing both secologanin and secoxyloganin allows enhanced de novo assembly of a Catharanthus roseus transcriptome

S. O’Connor, G. Glevarec, S. Besseau, 2015, BMC Genomics.

Biotechnological potential of the fungal CTG clade species in the synthetic biology era.

N. Papon, V. Courdavault, M. Clastre, 2014, Trends in biotechnology.

Isolation of CrHPt1, a cDNA encoding a histidine-containing phospho-transfer domain in Catharanthus roseus

N. Papon, M. Clastre, A. Oudin, 2002 .

Inhibition of the plant cytokinin transduction pathway by bacterial histidine kinase inhibitors in Catharanthus roseus cell cultures

P. Gantet, N. Papon, M. Clastre, 2003, FEBS letters.

A BAHD acyltransferase catalyzing 19‐O‐acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids

B. Schneider, S. O’Connor, G. Glevarec, 2018, The Plant journal : for cell and molecular biology.

Purification and Characterization of Cinnamoyl-Coenzyme A:NADP Oxidoreductase in €uca/ypfus gunnii’

Malcolm, A. Boudet, M. Clastre, 2002 .

Virus-induced gene silencing of the two squalene synthase isoforms of apple tree (Malus × domestica L.) negatively impacts phytosterol biosynthesis, plastid pigmentation and leaf growth

G. Glevarec, N. Yoshikawa, S. Besseau, 2017, Planta.

Vacuole-Targeted Proteins: Ins and Outs of Subcellular Localization Studies.

S. O’Connor, G. Glevarec, S. Besseau, 2018, Methods in molecular biology.

Genome-wide identification and biochemical characterization of the UGT88F subfamily in Malus x domestica Borkh.

G. Glevarec, S. Besseau, V. Courdavault, 2019, Phytochemistry.

Design, Synthesis and Evaluation of New Marine Alkaloid-Derived Pentacyclic Structures with Anti-Tumoral Potency

M. Clastre, J. Guillard, C. Mélin, 2015, Marine drugs.

Triple subcellular targeting of isopentenyl diphosphate isomerases encoded by a single gene

G. Glevarec, N. Papon, V. Courdavault, 2012, Plant signaling & behavior.

Characterization and subcellular localization of geranylgeranyl diphosphate synthase from Catharanthus roseus

S. Bouzid, A. Simkin, N. Papon, 2011, Molecular Biology Reports.

Expression analysis in plant and cell suspensions of CrCKR1, a cDNA encoding a histidine kinase receptor homologue in Catharanthus roseus (L.) G. Don.

P. Gantet, N. Papon, M. Clastre, 2002, Journal of experimental botany.

Identification of a second 16-hydroxytabersonine-O-methyltransferase suggests an evolutionary relationship between alkaloid and flavonoid metabolisms in Catharanthus roseus

Dinesh A Nagegowda, S. Besseau, N. Papon, 2022, Protoplasma.

Megaviruses: An involvement in phytohormone receptor gene transfer in brown algae?

J. Cock, N. Papon, V. Courdavault, 2019, Gene.

Two Tabersonine 6,7-Epoxidases Initiate Lochnericine-Derived Alkaloid Biosynthesis in Catharanthus roseus1

S. O’Connor, G. Glevarec, Thu-Thuy T. Dang, 2018, Plant Physiology.

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

S. O’Connor, E. Tatsis, Thu-Thuy T. Dang, 2017, Nature Communications.

A Biolistic-Mediated Virus-Induced Gene Silencing in Apocynaceae to Map Biosynthetic Pathways of Alkaloids.

S. Besseau, N. Papon, V. Courdavault, 2020, Methods in molecular biology.

Virus-induced gene silencing in Catharanthus roseus by biolistic inoculation of tobacco rattle virus vectors.

G. Glevarec, S. Besseau, N. Papon, 2015, Plant biology.

Virus-induced gene silencing in Rauwolfia species

G. Glevarec, S. Besseau, N. Papon, 2017, Protoplasma.

A single gene encodes isopentenyl diphosphate isomerase isoforms targeted to plastids, mitochondria and peroxisomes in Catharanthus roseus

G. Glevarec, N. Papon, V. Courdavault, 2012, Plant Molecular Biology.

A synthetic construct for genetic engineering of the emerging pathogenic yeast Candida auris.

A. Chowdhary, N. Papon, V. Courdavault, 2018, Plasmid.

Stilbenoid-Enriched Grape Cane Extracts for the Biocontrol of Grapevine Diseases

S. Besseau, V. Courdavault, M. Clastre, 2020 .

Two Tabersonine 6,7-Epoxidases Initiate Lochnericine-Derived Alkaloid Biosynthesis in Catharanthus roseus1

S. O’Connor, G. Glevarec, Thu-Thuy T. Dang, 2018, Plant Physiology.

Deus ex Candida genetics: overcoming the hurdles for the development of a molecular toolbox in the CTG clade.

A. Simkin, N. Papon, V. Courdavault, 2012, Microbiology.

Cycloheximide as a tool to investigate protein import in peroxisomes: a case study of the subcellular localization of isoprenoid biosynthetic enzymes.

A. Simkin, N. Papon, V. Courdavault, 2012, Journal of plant physiology.