P. Qasba

发表

Mutational analysis of the Golgi retention signal of bovine beta-1,4-galactosyltransferase.

P. V. Balaji, A. Masibay, E. Boeggeman, 1993, The Journal of biological chemistry.

Thyroid hormone regulation of alpha-lactalbumin: differential glycosylation and messenger ribonucleic acid synthesis in mouse mammary glands.

P. Qasba, B. Vonderhaar, S. Ziska, 1988, Endocrinology.

Mutant glycosyltransferases assist in the development of a targeted drug delivery system and contrast agents for MRI

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2006, The AAPS Journal.

Site-specific antibody-drug conjugation through an engineered glycotransferase and a chemically reactive sugar

Yang Feng, Ponraj Prabakaran, Simona Colantonio, 2014, mAbs.

Structure and catalytic cycle of β-1,4-galactosyltransferase

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2004 .

The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2.

B. Ramakrishnan, G. Griffiths, E. Boeggeman, 2012, Glycobiology.

Applications of Site-Specific Labeling to Study HAMLET, a Tumoricidal Complex of α-Lactalbumin and Oleic Acid

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2011, PloS one.

Galectin-1 as a fusion partner for the production of soluble and folded human beta-1,4-galactosyltransferase-T7 in E. coli.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2010, Biochemical and biophysical research communications.

Letter to the Glyco-Forum: catalytic domains of glycosyltransferases with 'add-on' domains.

B. Ramakrishnan, P. Qasba, 2007, Glycobiology.

Direct identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic method.

B. Ramakrishnan, L. Hsieh‐Wilson, J. Simpson, 2007, Bioconjugate chemistry.

Beta-1,4-galactosyltransferase and lactose synthase: molecular mechanical devices.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2002, Biochemical and biophysical research communications.

Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2004 .

Conformational analysis of Asn-linked oligosaccharides: implications in biological processes

P. V. Balaji, P. Qasba, V. Rao, 1997 .

Molecular dynamics simulations of hybrid and complex type oligosaccharides.

P. V. Balaji, P. Qasba, V. Rao, 1996, International journal of biological macromolecules.

Letter to the Glyco-Forum Controversial iduronate ring conformation in dermatan sulphate

P. V. Balaji, P. Qasba, V. Rao, 1995 .

2.07 – X-Ray Crystal Structures of Glycosyltransferases

B. Ramakrishnan, P. Qasba, 2007 .

Involvement of sugars in protein–protein interactions

P. Qasba, 2000 .

Molecular modeling studies on binding of bFGF to heparin and its receptor FGFR1.

P. Qasba, V. Rao, K. Lam, 1998, Journal of biomolecular structure & dynamics.

The N-terminal stem region of bovine and human beta1,4-galactosyltransferase I increases the in vitro folding efficiency of their catalytic domain from inclusion bodies.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2003, Protein expression and purification.

Bioconjugation and detection of lactosamine moiety using alpha1,3-galactosyltransferase mutants that transfer C2-modified galactose with a chemical handle.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2009, Bioconjugate chemistry.

Nucleic Acids Research Partial purification of rat «-lactalbumin mRNA

P. Qasba, K. Chakrabartty, 2005 .

Investigations on β1,4-galactosyltransferase I using 6-sulfo-GlcNAc as an acceptor sugar substrate

Tyler A. Davis, B. Ramakrishnan, P. Qasba, 2013, Glycoconjugate Journal.

Use of novel mutant galactosyltransferase for the bioconjugation of terminal N-acetylglucosamine (GlcNAc) residues on live cell surface.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2013, Bioconjugate chemistry.

Molecular dynamics simulations of asialoglycoprotein receptor ligands.

P. V. Balaji, P. Qasba, V. Rao, 1993, Biochemistry.

Molecular dynamics simulations of high-mannose oligosaccharides.

P. V. Balaji, P. Qasba, V. Rao, 1994, Glycobiology.

Molecular dynamics simulations of oligosaccharides and their conformation in the crystal structure of lectin-carbohydrate complex: importance of the torsion angle psi for the orientation of alpha 1,6-arm.

P. V. Balaji, P. Qasba, V. Rao, 1994, Glycobiology.

Site specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detection.

B. Ramakrishnan, A. Puri, E. Boeggeman, 2009, Bioconjugate chemistry.

Molecular cloning and sequence of a cDNA coding for bovine lipoprotein lipase.

Y. Furuichi, P. Qasba, W. Brown, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Structure and Function of -1,4-Galactosyltransferase

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2008 .

Glycans of Antibodies as a Specific Site for Drug Conjugation Using Glycosyltransferases.

P. Qasba, 2015, Bioconjugate chemistry.

Multiple site-specific in vitro labeling of single-chain antibody.

B. Ramakrishnan, D. Dimitrov, Zhongyu Zhu, 2009, Bioconjugate chemistry.

Alkaline transfer of DNA to plastic membrane.

P. Chomczyński, P. Qasba, 1984, Biochemical and biophysical research communications.

Structure-based evolutionary relationship of glycosyltransferases: a case study of vertebrate β1,4-galactosyltransferase, invertebrate β1,4-N-acetylgalactosaminyltransferase and α-polypeptidyl-N-acetylgalactosaminyltransferase.

B. Ramakrishnan, P. Qasba, 2010, Current opinion in structural biology.

Protein-coding capacities of polyadenylated RNAs from normal and neoplastic rat mammary tissues.

P. Qasba, T. Horn, J. Sodroski, 1983, Cancer research.

Complete sequence analysis of cDNA clones encoding rat whey phosphoprotein: homology to a protease inhibitor.

E. Appella, E. Robinson, P. Qasba, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Identification and partial characterization of genes that are transactivated by different pathways in quiescent mouse cells stimulated with serum

A. Masibay, E. Boeggeman, P. Qasba, 1990, Journal of cellular physiology.

Cell-cycle-specific and serum-dependent expression of gamma-actin mRNA in Swiss mouse 3T3 cells

A. Masibay, P. Qasba, D. Sengupta, 1988, Molecular and cellular biology.

Expression of beta-1,4-galactosyltransferase gene during 3T3 cell growth.

A. Masibay, E. Boeggeman, P. Qasba, 1991, Biochimica et biophysica acta.

Active site studies of bovine alpha1-->3-galactosyltransferase and its secondary structure prediction.

P. S. Shah, R. Dukor, P. Qasba, 2000, Biochimica et biophysica acta.

Milk protein gene expression in the rat mammary gland.

H. Nakhasi, P. Qasba, E. Devinoy, 1982, Critical reviews in food science and nutrition.

Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2005, Biochemistry.

Formation of nucleoprotein complexes between polyoma empty capsides and DNA

R. E. Thayer, P. Qasba, H. Aposhian, 1975, Journal of virology.

Deletion analysis of the NH2-terminal region of β-1,4-galactosyltransferase

A. Masibay, E. Boeggeman, P. Qasba, 1992, Molecular Biology Reports.

Formation ofNucleoprotein Complexes Between Polyoma EmptyCapsids andDNA

R. E. Thayer, P. Qasba, H. Aposhian, 1975 .

Improved synthesis of UDP-2-(2-ketopropyl)galactose and a first synthesis of UDP-2-(2-ketopropyl)glucose for the site-specific linking of biomolecules via modified glycan residues using glycosyltransferases.

G. Griffiths, P. Qasba, Andrés E. Dulcey, 2011, Tetrahedron.

A chemoenzymatic approach toward the rapid and sensitive detection of O-GlcNAc posttranslational modifications.

Linda C Hsieh-Wilson, B. Ramakrishnan, Nathan Lamarre-Vincent, 2003, Journal of the American Chemical Society.

Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I.

B. Ramakrishnan, P. Qasba, P K Qasba, 2001, Journal of molecular biology.

Studies on the metal binding sites in the catalytic domain of beta1,4-galactosyltransferase.

E. Boeggeman, P. Qasba, 2002, Glycobiology.

Structural snapshots of beta-1,4-galactosyltransferase-I along the kinetic pathway.

B. Ramakrishnan, P. Qasba, V. Ramasamy, 2006, Journal of molecular biology.

Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity.

B. Ramakrishnan, P. Qasba, 2002, The Journal of biological chemistry.

Binding of N-Acetylglucosamine (GlcNAc) β1–6-branched Oligosaccharide Acceptors to β4-Galactosyltransferase I Reveals a New Ligand Binding Mode*

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2012, The Journal of Biological Chemistry.

Substrate-induced conformational changes in glycosyltransferases.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2005, Trends in biochemical sciences.

Galactosyltransferase purified from rat milk is distinct from the human and bovine enzyme.

H. Nakhasi, P. Qasba, K. Daruwalla, 1986, Journal of dairy science.

Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase.

K. Brew, H. Okayama, H. Narimatsu, 1986, Proceedings of the National Academy of Sciences of the United States of America.

alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.

B. Ramakrishnan, P. S. Shah, P. Qasba, 2001, The Journal of biological chemistry.

- Lactalbumin ( LA ) Stimulates Milk-1 , 4-Galactosyltransferase I ( 4 GalT 1 ) to Transfer Glucose from UDP-glucose to N-Acetylglucosamine CRYSTAL STRUCTURE OF 4 GalT 1 LA COMPLEX WITH UDP-Glc

B. Ramakrishnan, P. S. Shah, P. Qasba, 2001 .

UDP-Gal: BetaGlcNAc Beta 1,4-Galactosyltransferase, Polypeptide 1 (B4GALT1)

B. Ramakrishnan, P. Qasba, 2014 .

Deoxygenated Disaccharide Analogs as Specific Inhibitors of β1–4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis*

B. Ramakrishnan, J. Esko, J. Brown, 2009, Journal of Biological Chemistry.

Role of a single amino acid in the evolution of glycans of invertebrates and vertebrates.

B. Ramakrishnan, P. Qasba, 2007, Journal of molecular biology.

Oligosaccharide preferences of beta1,4-galactosyltransferase-I: crystal structures of Met340His mutant of human beta1,4-galactosyltransferase-I with a pentasaccharide and trisaccharides of the N-glycan moiety.

B. Ramakrishnan, P. Seeberger, D. Ratner, 2005, Journal of molecular biology.

Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2004, Biochemistry.

The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2003, Journal of molecular biology.

Crystal structure of beta1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding site.

B. Ramakrishnan, P. V. Balaji, P. Qasba, 2002, Journal of molecular biology.

α-Lactalbumin (LA) Stimulates Milk β-1,4-Galactosyltransferase I (β4Gal-T1) to Transfer Glucose from UDP-glucose to N-Acetylglucosamine

B. Ramakrishnan, P. S. Shah, P. Qasba, 2001, Journal of Biological Chemistry.

Molecular divergence of lysozymes and alpha-lactalbumin.

P. Qasba, S. Kumar, Soma Kumar, 1997, Critical reviews in biochemistry and molecular biology.

Functional domains of bovine β-1,4 galactosyltransferase

P. V. Balaji, E. Boeggeman, P. Qasba, 1995, Glycoconjugate Journal.

Alpha‐lactalbumin‐like Proteins in the Male Reproductive Tract a

S. Byers, I. Hewlett, M. Dym, 1984, Annals of the New York Academy of Sciences.

Expression of deletion constructs of bovine beta-1,4-galactosyltransferase in Escherichia coli: importance of Cys134 for its activity.

P. V. Balaji, A. Masibay, E. Boeggeman, 1993, Protein engineering.

The presence of the milk protein, α-lactalbumin and its mRNA in the rat epididymis

S. Byers, I. Hewlett, P. Qasba, 1983 .

Purification and properties of two forms of rat alpha-lactalbumin.

P. Qasba, P. K. Chakrabartty, 1978, The Journal of biological chemistry.

P. Qasba, S. Safaya, 1984, Nature.

Rat alpha-lactalbumin has a 17-residue-long COOH-terminal hydrophobic extension as judged by sequence analysis of the cDNA clones.

P. Qasba, A. M. Dandekar, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Crystal Structures of β-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding*

B. Ramakrishnan, Y. Tsutsui, P. Qasba, 2013, The Journal of Biological Chemistry.

Crystal Structure of the Catalytic Domain of Drosophila β1,4-Galactosyltransferase-7*

B. Ramakrishnan, P. Qasba, 2010, The Journal of Biological Chemistry.

Glycolipid antigen processing for presentation by CD1d molecules.

A. Kulkarni, M. Kronenberg, D. Elewaut, 2001, Science.

Dicyclohexylamine effects on HTC cell polyamine content and ornithine decarboxylase activity.

P. McCann, P. Qasba, J. L. Mitchell, 1985, Biochimica et biophysica acta.

Ornithine decarboxylase modification and polyamine-stimulated enzyme inactivation in HTC cells.

P. Qasba, J. L. Mitchell, M. Franzén, 1985, The Biochemical journal.

Expression of lipoprotein lipase gene in combined lipase deficiency.

R. Scow, A. Masibay, P. Qasba, 1989, Biochimica et biophysica acta.

Expression of beta-1,4-galactosyltransferase gene during 3T3 cell growth.

A. Masibay, E. Boeggeman, P. Qasba, 1991, Biochimica et biophysica acta.

Structure and function of beta -1,4-galactosyltransferase.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2008, Current drug targets.

a-Lactalbumin Contentof RatMammaryCarcinomas andthe Effect of PituitaryStimulation

P. Qasba, M. Gulllno, 1977 .

alpha-Lactalbumin content of rat mammary carcinomas and the effect of pituitary stimulation.

P. Gullino, P. Qasba, 1977, Cancer research.

Expression of human aspartyl-tRNA synthetase in COS cells

C. Escalante, David C. H. Yang, P. Qasba, 1994, Molecular and Cellular Biochemistry.

alpha-Lactalbumin mRNA in 4-day lactating rat mammary gland.

H. Nakhasi, P. Qasba, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Nature of RNA synthesized at low and high ionic strength by DNA-dependent RNA-polymerase from Escherichia coli.

W. Zillig, P. Qasba, 1969, European journal of biochemistry.

Synthesis of simian virus 40 DNA in isolated nuclei.

P. Qasba, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of the Closed Conformation of the β1,4-galactosyltransferase-1 (β4Gal-T1) in the Presence and Absence of α-lactalbumin (LA)

B. Ramakrishnan, P. Qasba, 2003 .

Iterative cluster‐NMA: A tool for generating conformational transitions in proteins

G. Chirikjian, B. Ramakrishnan, R. Jernigan, 2009, Proteins.

Kinetics of the alteration and modification of DNA-dependent RNA-polymerase in T4-infected E. coli cells.

G. Walter, M. Schachner, W. Zillig, 1969, European journal of biochemistry.

Structure and catalytic cycle of beta-1,4-galactosyltransferase.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2004, Current opinion in structural biology.

Architecture of the sugar binding sites in carbohydrate binding proteins--a computer modeling study.

P. Qasba, V S Rao, K Lam, 1998, International journal of biological macromolecules.

Three dimensional structure of the soybean agglutinin Gal/GalNAc complexes by homology modeling.

P. Qasba, V. Rao, King Lam, 1998, Journal of biomolecular structure & dynamics.

Iterative cluster-NMA ( icNMA ) : A tool for generating conformational transitions in proteins

Gregory S. Chirikjian, Adam D. Schuyler, Robert L. Jernigan, 2017 .

DNA and gene therapy: transfer of mouse DNA to human and mouse embryonic cells by polyoma pseudovirions.

P. Qasba, H. Aposhian, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Interdependence of backbone flexibility, residue conservation, and enzyme function: a case study on beta1,4-galactosyltransferase-I.

R. Nussinov, B. Ramakrishnan, B. Ma, 2003, Biochemistry.

Molecular dynamics simulation of α-lactalbumin and calcium binding c-type lysozyme

P. Qasba, Pradman K. Qasba, Lakshmanan K. Iyer, 1999 .

Applications of glycosyltransferases in the site-specific conjugation of biomolecules and the development of a targeted drug delivery system and contrast agents for MRI

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2008, Expert Opinion on Drug Delivery.

Iterative cluster‐NMA: A tool for generating conformational transitions in proteins

G. Chirikjian, A. Schuyler, P. Qasba, 2009, Proteins.

The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2.

B. Ramakrishnan, G. Griffiths, E. Boeggeman, 2012, Glycobiology.

Novel method for in vitro O-glycosylation of proteins: application for bioconjugation.

B. Ramakrishnan, E. Boeggeman, P. Qasba, 2007, Bioconjugate chemistry.

Immunocytochemical localization of alpha-lactalbumin in the male reproductive tract.

H. Paulson, S. Byers, M. Dym, 1984, Biology of reproduction.