Radhakrishnan Kanagaraj

发表

The zinc-binding motif of human RECQ5beta suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme.

X. Xi, Pengye Wang, Hua Ren, 2008, The Biochemical journal.

Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity*

Jeremy M. Stark, Shreya Paliwal, Anita Cheng, 2010, The Journal of Biological Chemistry.

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

T. Ha, Radhakrishnan Kanagaraj, P. Janscak, 2009, The EMBO journal.

RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis.

S. Di Marco, Hana Sedlackova, S. Ferrari, 2017, Molecular cell.

A deep learning workflow for quantification of Micronuclei in DNA damage studies in cultured cancer cell lines: a proof of principle investigation

John J Murphy, K. Surendranath, Radhakrishnan Kanagaraj, 2022, bioRxiv.

AU-Rich Element RNA Binding Proteins: At the Crossroads of Post-Transcriptional Regulation and Genome Integrity

John J Murphy, K. Surendranath, Radhakrishnan Kanagaraj, 2021, International journal of molecular sciences.

DNA2 Cooperates with the WRN and BLM RecQ Helicases to Mediate Long-range DNA End Resection in Human Cells*

Radhakrishnan Kanagaraj, P. Janscak, P. Cejka, 2014, The Journal of Biological Chemistry.

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing

Radhakrishnan Kanagaraj, P. Janscak, Shreya Paliwal, 2013, Nucleic acids research.

GEN1 promotes common fragile site expression.

S. West, Radhakrishnan Kanagaraj, Monica C. Rodrigo-Brenni, 2023, Cell reports.

Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2

Fengtang Yang, S. West, A. Koren, 2021, Proceedings of the National Academy of Sciences.

Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies MCM10 as a novel regulator of the replication program

S. West, A. Koren, N. Benvenisty, 2021, bioRxiv.

RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

A. Greenleaf, M. Menigatti, I. Shevelev, 2010, Nucleic acids research.

Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage

V. Bohr, U. Hübscher, P. Parasuraman, 2012, Nucleic acids research.

MRE11 complex links RECQ5 helicase to sites of DNA damage

B. Gerrits, I. Shevelev, Radhakrishnan Kanagaraj, 2009, Nucleic acids research.

Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

Radhakrishnan Kanagaraj, P. Janscak, N. Saydam, 2006, Nucleic acids research.

Excessive reactive oxygen species induce transcription-dependent replication stress

M. Lopes, H. Stoy, K. Surendranath, 2023, Nature Communications.

DDX17 helicase promotes resolution of R-loop-mediated transcription–replication conflicts in human cells

Radhakrishnan Kanagaraj, P. Janscak, Zuzana Nascakova, 2022, Nucleic acids research.

Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors

Igor Stagljar, I. Stagljar, I. Shevelev, 2007, Nucleic acids research.

Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation.

S. West, A. Koren, N. Benvenisty, 2022, Human molecular genetics.

RNA-Binding Proteins and Their Emerging Roles in Cancer: Beyond the Tip of the Iceberg

K. Surendranath, Radhakrishnan Kanagaraj, John J. Murphy, 2023, International journal of molecular sciences.

RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis.

S. Di Marco, Hana Sedlackova, S. Ferrari, 2017, Molecular cell.