M. Iwadate

发表

Community‐wide evaluation of methods for predicting the effect of mutations on protein–protein interactions

Julie C. Mitchell, Jeffrey J. Gray, Z. Weng, 2013, Proteins.

Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target

Kun-Yi Hsin, Hiroaki Kitano, Y-h. Taguchi, 2015, Scientific Reports.

HUMAN FAMSD-BASE: high quality protein structure model database for the human genome using the FAMSD homology modeling method.

Genki Terashi, Mayuko Takeda-Shitaka, M. Iwadate, 2010, Chemical & pharmaceutical bulletin.

FAMSD: A powerful protein modeling platform that combines alignment methods, homology modeling, 3D structure quality estimation and molecular dynamics.

Genki Terashi, Mitsuo Iwadate, Hideaki Umeyama, 2009, Chemical & pharmaceutical bulletin.

A prospective compound screening contest identified broader inhibitors for Sirtuin 1

Shogo D. Suzuki, Hironori K. Nakamura, Kazuki Z. Yamamoto, 2019, Scientific Reports.

In silico Spleen Tyrosine Kinase Inhibitor Screening by ChooseLD

Y-h. Taguchi, M. Iwadate, H. Umeyama, 2015, Inf. Media Technol..

Development of a novel anti-hepatitis B virus agent via Sp1

T. Honda, A. Tamori, Y. Yano, 2020, Scientific Reports.

Evaluation of homology modeling of the severe acute respiratory syndrome (SARS) coronavirus main protease for structure based drug design.

Mayuko Takeda-Shitaka, M. Iwadate, H. Umeyama, 2004, Chemical & pharmaceutical bulletin.

Bacterial Type III Secretion System Effector Proteins are Distinct between Plant Symbiotic, Plant Pathogenic and Animal Pathogenic Bacteria

Y-h. Taguchi, M. Iwadate, H. Umeyama, 2014 .

Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome.

E. Ito, T. Miyata, K. Kokame, 2003, Blood.

Method for predicting homology modeling accuracy from amino acid sequence alignment: the power function.

Genki Terashi, Mayuko Takeda-Shitaka, M. Iwadate, 2010, Chemical & pharmaceutical bulletin.

Driving forces of biomolecular organisation specific to nanometer scale: protein orientation on the surface, controlled by pH level

Y. Shirshov, B. Snopok, P. Boltovets, 2001 .

Core I97L mutation in conjunction with P79Q is associated with persistent low HBV DNA and HBs antigen clearance in patients with chronic hepatitis B.

Y. Hirooka, H. Goto, T. Honda, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

patients with Upshaw-Schulman syndrome Molecular characterization of ADAMTS13 gene mutations in Japanese

E. Ito, K. Kokame, T. Nakagaki, 2013 .

Development of novel hepatitis B virus capsid inhibitor using in silico screening.

A. Tamori, Y. Yano, N. Kawada, 2015, Biochemical and biophysical research communications.

Solid phase synthesis and biological activities of [Arg8]-vasopressin methylenedithioether.

M. Ueki, M. Williamson, T. Asakura, 1999, Bioorganic & medicinal chemistry letters.

Interaction of mastoparan with membranes studied by 1H-NMR spectroscopy in detergent micelles and by solid-state 2H-NMR and 15N-NMR spectroscopy in oriented lipid bilayers.

T. Niidome, M. Demura, T. Asakura, 2001, European journal of biochemistry.

The structure of the melittin tetramer at different temperatures--an NOE-based calculation with chemical shift refinement.

M. Williamson, T. Asakura, M. Iwadate, 1998, European journal of biochemistry.

Structure determination of [Arg8]vasopressin methylenedithioether in dimethylsulfoxide using NMR.

M. Williamson, T. Asakura, M. Iwadate, 2000, European journal of biochemistry.

An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes

Daisuke Kihara, Takashi Ishida, Masakazu Sekijima, 2017, Scientific Reports.

Cα and Cβ Carbon-13 Chemical Shifts in Proteins From an Empirical Database

Mitsuo Iwadate, Michael P. Williamson, Tetsuo Asakura, 1999 .

Molecular Dynamics Simulations to Determine the Structure and Dynamics of Hepatitis B Virus Capsid Bound to a Novel Anti-viral Drug.

M. Iwadate, H. Umeyama, Y. Murakami, 2016, Chemical & pharmaceutical bulletin.

Discovering novel direct acting antiviral agents for HBV using in silico screening.

A. Tamori, Y. Yano, N. Kawada, 2015, Biochemical and biophysical research communications.

Enlarged FAMSBASE: protein 3D structure models of genome sequences for 41 species

Akihiro Yamaguchi, Kei Yura, Mitsuo Iwadate, 2003, Nucleic Acids Res..

Genes associated with genotype-specific DNA methylation in squamous cell carcinoma as candidate drug targets

Y-h. Taguchi, Mitsuo Iwadate, Hideaki Umeyama, 2014, BMC Systems Biology.

Principal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart disease

Y-h. Taguchi, M. Iwadate, H. Umeyama, 2015, BMC Bioinformatics.

Principal component analysis based unsupervised feature extraction applied to bioinformatics analysis

Yoshiki Murakami, Y-h. Taguchi, Mitsuo Iwadate, 2017 .

SFRP1 is a possible candidate for epigenetic therapy in non-small cell lung cancer

Y-h. Taguchi, M. Iwadate, H. Umeyama, 2016, BMC Medical Genomics.

Heuristic principal component analysis-based unsupervised feature extraction and its application to gene expression analysis of amyotrophic lateral sclerosis data sets

Y-h. Taguchi, Mitsuo Iwadate, Hideaki Umeyama, 2015, 2015 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB).

TINAGL1 and B3GALNT1 are potential therapy target genes to suppress metastasis in non-small cell lung cancer

Mitsuo Iwadate, Hideaki Umeyama, Y-h. Taguchi, 2014, BMC Genomics.

Heuristic principal component analysis based unsupervised feature extraction and its application to bioinformatics

Yoshiki Murakami, Y-h. Taguchi, Akira Okamoto, 2014 .

Bioinformatic Screening of Autoimmune Disease Genes and Protein Structure Prediction with FAMS for Drug Discovery

Mitsuo Iwadate, Hideaki Umeyama, Shigeharu Ishida, 2013, Protein and peptide letters.

TINAGL1 and B3GALNT1 are potential therapy target genes to suppress metastasis in non-small cell lung cancer

Y-h. Taguchi, M. Iwadate, H. Umeyama, 2014, BMC Genomics.

Bioinformatics based Ligand-Docking and in-silico screening.

Genki Terashi, Mitsuo Iwadate, Daisuke Takaya, 2008, Chemical & pharmaceutical bulletin.

Structure Prediction with FAMS for Proteins Screened Critically to Autoimmune Diseases based upon Bioinformatics

Y-h. Taguchi, Mitsuo Iwadate, Hideaki Umeyama, 2012, BIOINFORMATICS.

Structural analysis of silk with 13C NMR chemical shift contour plots.

M. Williamson, M. Demura, T. Asakura, 1999, International Journal of Biological Macromolecules.

Supporting Information : Previous studies that reported the relationship between cancers / tumors and top most feasible drug canridate compounds selected for ALK , ELGN 3 and NUAK 1

M. Iwadate, H. Umeyama, Y-h. Taguchi, 2013 .

Pressure-dependent changes in the structure of the melittin α-helix determined by NMR

M. Williamson, T. Asakura, M. Iwadate, 2001 .

Fams‐ace: A combined method to select the best model after remodeling all server models

Genki Terashi, Mayuko Takeda-Shitaka, Kazuhiko Kanou, 2007, Proteins.

An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes

Shogo D. Suzuki, Kazuki Z. Yamamoto, D. Kihara, 2017, Scientific Reports.

C alpha and C beta carbon-13 chemical shifts in proteins from an empirical database.

M. Williamson, T. Asakura, M. Iwadate, 1999, Journal of biomolecular NMR.

FAMS and FAMSBASE for Protein Structure

Hideaki Umeyama, Mitsuo Iwadate, M. Iwadate, 2003, Current protocols in bioinformatics.

Principal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart disease

Y-h. Taguchi, Mitsuo Iwadate, Hideaki Umeyama, 2015, BMC Bioinformatics.

Core I97L mutation in conjunction with P79Q is associated with persistent low HBV DNA and HBs antigen clearance in patients with chronic hepatitis B.

Y. Hirooka, H. Goto, T. Kuzuya, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.