W. Voos

发表

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

N. Pfanner, R. Zahedi, A. Sickmann, 2009, Cell.

The Mitochondrial Protein Import Motor

N. Pfanner, J. Lim, W. Voos, 2000, Biological chemistry.

A. Merlin, N. Pfanner, W. Voos, 1999, The Journal of cell biology.

A J-protein is an essential subunit of the presequence translocase–associated protein import motor of mitochondria

N. Pfanner, A. Sickmann, Jan Dudek, 2003, The Journal of cell biology.

The Presequence Translocase-associated Protein Import Motor of Mitochondria

N. Pfanner, Jan Dudek, P. Rehling, 2004, Journal of Biological Chemistry.

Pam16 has an essential role in the mitochondrial protein import motor

N. Pfanner, A. Sickmann, Jan Dudek, 2004, Nature Structural &Molecular Biology.

Mitochondrial Import of Subunit Va of Cytochrome c Oxidase Characterized with Yeast Mutants

E. Craig, N. Pfanner, A. Querol, 1995, The Journal of Biological Chemistry.

Pink1 and its Δψ -dependent cleavage product both localize to the outer mitochondrial membrane by a unique targeting mode*

S. Przedborski, D. Becker, W. Voos, 2012 .

Pink1 Kinase and Its Membrane Potential (Δψ)-dependent Cleavage Product Both Localize to Outer Mitochondrial Membrane by Unique Targeting Mode*

S. Przedborski, D. Becker, W. Voos, 2012, The Journal of Biological Chemistry.

IMiQ: a novel protein quality control compartment protecting mitochondrial functional integrity

G. Cenini, M. Sylvester, W. Voos, 2017, Molecular biology of the cell.

IMiQC: a novel protein quality control compartment protecting mitochondrial functional integrity

G. Cenini, M. Sylvester, W. Voos, 2016, bioRxiv.

The two mitochondrial heat shock proteins 70, Ssc1 and Ssq1, compete for the cochaperone Mge1.

N. Zufall, W. Voos, A. Strub, 2001, Journal of molecular biology.

Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM–TIM–preprotein supercomplex

N. Pfanner, P. Rehling, C. Meisinger, 2003, The EMBO journal.

Mitochondrial Protein Import in Fungi and Animals

D. Becker, W. Voos, U. Seibold, 2011 .

α-Synuclein Is Localized to Mitochondria-Associated ER Membranes

E. Schon, S. Przedborski, D. Becker, 2014, The Journal of Neuroscience.

Atad3 Function Is Essential for Early Post-Implantation Development in the Mouse

E. Kremmer, W. Kolanus, W. Voos, 2013, PloS one.

Assaying protein import into mitochondria.

N. Pfanner, M. Ryan, W. Voos, 2001, Methods in cell biology.

The disaggregation activity of the mitochondrial ClpB homolog Hsp78 maintains Hsp70 function during heat stress.

W. Voos, T. Major, B. von Janowsky, 2006, Journal of molecular biology.

The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis and activity control.

K. Truscott, W. Voos, L. Ward, 2013, Sub-cellular biochemistry.

Chaperones and Proteases of Mitochondria: From Protein Folding and Degradation to Mitophagy

W. Voos, Michael Bruderek, Cornelia Rüb, 2014 .

Analysis of heat-induced protein aggregation in human mitochondria

M. Sylvester, W. Voos, Anne Wilkening, 2018, The Journal of Biological Chemistry.

The mitochondrial Hsp70‐dependent import system actively unfolds preproteins and shortens the lag phase of translocation

N. Pfanner, F. Martin, B. Guiard, 2001, The EMBO journal.

The Import Route of ADP/ATP Carrier into Mitochondria Separates from the General Import Pathway of Cleavable Preproteins at thetrans Side of the Outer Membrane*

N. Pfanner, W. Voos, J. Rassow, 1998, The Journal of Biological Chemistry.

The Functional Interaction of Mitochondrial Hsp70s with the Escort Protein Zim17 Is Critical for Fe/S Biogenesis and Substrate Interaction at the Inner Membrane Preprotein Translocase*

M. van der Laan, B. Guiard, R. Lill, 2013, The Journal of Biological Chemistry.

Chaperones and Proteases—Guardians of Protein Integrity in Eukaryotic Organelles

Claudia Leidhold, W. Voos, 2007, Annals of the New York Academy of Sciences.

Analysis of heat-induced protein aggregation in human mitochondria

M. Sylvester, W. Voos, Anne Wilkening, 2018, The Journal of Biological Chemistry.

Complex with hsp7O and Preproteins in Transit across Membranes

D. Ang, E. Craig, W. Voos, 2022 .

Role of Mitochondrial Protein Import in Age-Related Neurodegenerative and Cardiovascular Diseases

V. Gordeliy, T. Gensch, N. Dencher, 2021, Cells.

Mitochondrial quality control by the Pink1/Parkin system

W. Voos, Anne Wilkening, Cornelia Rüb, 2016, Cell and Tissue Research.

Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy

S. Przedborski, D. Becker, W. Voos, 2014, EMBO reports.

Protein quality control at the mitochondrion.

W. Voos, Michael Bruderek, Witold Jaworek, 2016, Essays in biochemistry.

The ClpB Homolog Hsp78 Is Required for the Efficient Degradation of Proteins in the Mitochondrial Matrix*

B. Guiard, N. Zufall, W. Voos, 2002, The Journal of Biological Chemistry.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

A Cooperative Action of the ATP-Dependent Import Motor Complex and the Inner Membrane Potential Drives Mitochondrial Preprotein Import

F. Martin, B. Guiard, W. Voos, 2006, Molecular and Cellular Biology.

Tom40: more than just a channel

W. Voos, 2003, Nature Structural Biology.

Tim50 Maintains the Permeability Barrier of the Mitochondrial Inner Membrane

N. Pfanner, P. Rehling, M. Meinecke, 2006, Science.

Precursor proteins in transit through mitochondrial contact sites interact with hsp70 in the matrix

W. Neupert, E. Craig, N. Pfanner, 1990, FEBS letters.

Fluorescence-mediated analysis of mitochondrial preprotein import in vitro.

B. Guiard, W. Voos, K. Paal, 2006, Analytical biochemistry.

Putative promoter elements for the ribosomal RNA genes of the thermoacidophilic archaebacterium Sulfolobus sp. strain B12.

W. Zillig, W. Voos, W. Schulz, 1987, Nucleic acids research.

Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy.

H. Neumann, E. Hattingen, P. Nürnberg, 2016, Brain : a journal of neurology.

Protein Translocation into Mitochondria

W. Voos, A. Strub, S. Schmidt, 2001, Neurosignals.

Intramitochondrial dimerization of citrate synthase characterized by blue native electrophoresis.

W. Voos, J. Rassow, S. Reif, 2001, Analytical biochemistry.

In vitro analysis of the mitochondrial preprotein import machinery using recombinant precursor polypeptides.

D. Becker, W. Voos, 2015, Methods in molecular biology.

In vitro analysis of the mitochondrial preprotein import machinery using recombinant precursor polypeptides.

D. Becker, W. Voos, Martin Krayl, 2008, Methods in molecular biology.

Structure and function of Hsp78, the mitochondrial ClpB homolog.

D. Becker, Claudia Leidhold, W. Voos, 2006, Journal of structural biology.

γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice

M. Memo, G. Cenini, D. Uberti, 2019, Nutrients.

Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration

R. Nussbaum, A. Reichert, A. Kurz, 2009, PloS one.

Chaperone-protease networks in mitochondrial protein homeostasis.

W. Voos, 2013, Biochimica et biophysica acta.

Mitochondrial protein homeostasis: the cooperative roles of chaperones and proteases.

W. Voos, 2009, Research in microbiology.

The Protein Import Motor of Mitochondria Unfolding and Trapping of Preproteins Are Distinct and Separable Functions of Matrix Hsp70

Wolfgang Voos, E. Craig, N. Pfanner, 1999, Cell.

A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins

T. Langer, E. Craig, N. Pfanner, 1993, The Journal of cell biology.

The putative helical lid of the Hsp70 peptide-binding domain is required for efficient preprotein translocation into mitochondria.

N. Zufall, W. Voos, A. Strub, 2003, Journal of molecular biology.

Mitochondrial Import Driving Forces: Enhanced Trapping by Matrix Hsp70 Stimulates Translocation and Reduces the Membrane Potential Dependence of Loosely Folded Preproteins

Wolfgang Voos, N. Pfanner, W. Voos, 2001, Molecular and Cellular Biology.

Molecular chaperones as essential mediators of mitochondrial biogenesis.

W. Voos, K. Röttgers, 2002, Biochimica et biophysica acta.

Mitochondrial GrpE modulates the function of matrix Hsp70 in translocation and maturation of preproteins

E. Craig, N. Pfanner, P. Dekker, 1995, Molecular and cellular biology.

Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update

G. Cenini, W. Voos, 2019, Front. Pharmacol..

Proteomic analysis demonstrates the role of the quality control protease LONP1 in mitochondrial protein aggregation

M. Sylvester, W. Voos, Karen Pollecker, 2021, The Journal of biological chemistry.

The role of protein quality control in mitochondrial protein homeostasis under oxidative stress

S. Franken, Claudia Leidhold, W. Voos, 2010, Proteomics.

Proteomic Analysis of Mitochondrial Protein Turnover: Identification of Novel Substrate Proteins of the Matrix Protease Pim1

A. Mogk, W. Voos, T. Ruppert, 2006, Molecular and Cellular Biology.

Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process

G. Cenini, W. Voos, Michael Bruderek, 2016, bioRxiv.

Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease

S. Franken, W. Voos, Catherina Baitzel, 2011, Molecular biology of the cell.

The mitochondrial ClpB homolog Hsp78 cooperates with matrix Hsp70 in maintenance of mitochondrial function.

B. Schönfisch, N. Pfanner, W. Voos, 1995, Journal of molecular biology.

A new connection: chaperones meet a mitochondrial receptor.

W. Voos, 2003, Molecules and Cells.

Mechanisms of protein translocation into mitochondria.

N. Pfanner, W. Voos, T. Krimmer, 1999, Biochimica et biophysica acta.

Partner proteins determine multiple functions of Hsp70.

N. Pfanner, W. Voos, N Pfanner, 1995, Trends in cell biology.

Impaired Interdomain Communication in Mitochondrial Hsp70 Results in the Loss of Inward-directed Translocation Force*

M. Mayer, D. Becker, W. Voos, 2009, Journal of Biological Chemistry.

The Hsp70 peptide‐binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria

W. Voos, A. Strub, K. Röttgers, 2002, The EMBO journal.

Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress

G. Cenini, M. Sylvester, W. Voos, 2022, The Journal of biological chemistry.

Hsp78-interaction proteome highlights chaperone role during protein aggregation in mitochondria under heat stress

G. Cenini, M. Sylvester, W. Voos, 2022, bioRxiv.

Proteomic analysis of the role of the quality control protease LONP1 in mitochondrial protein aggregation

M. Sylvester, W. Voos, Karen Pollecker, 2021, bioRxiv.

Mitochondrial Protein Import Motor: the ATPase Domain of Matrix Hsp70 Is Crucial for Binding to Tim44, while the Peptide Binding Domain and the Carboxy-Terminal Segment Play a Stimulatory Role

N. Pfanner, W. Voos, T. Krimmer, 2000, Molecular and Cellular Biology.

One Single In-frame AUG Codon Is Responsible for a Diversity of Subcellular Localizations of Glutaredoxin 2 in Saccharomyces cerevisiae*

P. Porras, J. Bárcena, W. Voos, 2006, Journal of Biological Chemistry.

Retrieval of Resident Late-Golgi Membrane Proteins from the Prevacuolar Compartment of Saccharomyces cerevisiae Is Dependent on the Function of Grd19p

T. Stevens, W. Voos, 1998, The Journal of cell biology.

Protein unfolding by mitochondria

N. Pfanner, A. Matouschek, W. Voos, 2000, EMBO reports.

The Hsp70 import motor

N. Pfanner, A. Matouschek, W. Voos, 2000 .

Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix

E. Craig, N. Pfanner, B. Guiard, 1993, The Journal of cell biology.

Accessing Mitochondrial Protein Import in Living Cells by Protein Microinjection

V. Gordeliy, A. Schulga, T. Gensch, 2020, bioRxiv.

Transport of proteins into mitochondria.

N. Pfanner, K. Truscott, W. Voos, 2001, Reviews of physiology, biochemistry and pharmacology.

The essential yeast protein MIM44 (encoded by MPI1) is involved in an early step of preprotein translocation across the mitochondrial inner membrane

L. Grivell, N. Pfanner, P. Dekker, 1993, Molecular and cellular biology.

Targeting and translocation of the phosphate carrier/p32 to the inner membrane of yeast mitochondria.

J. Schlossmann, K. Dietmeier, N. Pfanner, 1993, The Journal of biological chemistry.

Differential requirement for the mitochondrial Hsp70‐Tim44 complex in unfolding and translocation of preproteins.

N. Pfanner, B. Guiard, H. Müller, 1996, The EMBO journal.

The role of molecular chaperones in transport of proteins across membranes

E. Craig, N. Pfanner, W. Voos, 1995 .

The Mitochondrial Lon Protease: Novel Functions off the Beaten Track?

W. Voos, Karen Pollecker, 2020, Biomolecules.

Structural properties of substrate proteins determine their proteolysis by the mitochondrial AAA+ protease Pim1

B. Guiard, W. Voos, T. Major, 2005, Biological chemistry.

Biochemical properties of the kinase PINK1 as sensor protein for mitochondrial damage signalling.

N. Schröder, W. Voos, Cornelia Rüb, 2015, Biochemical Society transactions.

Mitochondrial GrpE is present in a complex with hsp70 and preproteins in transit across membranes.

D. Ang, E. Craig, N. Pfanner, 1994, Molecular and cellular biology.

Mitochondrial protein biogenesis: The essential functions of chaperones and their cofactors during preprotein translocation

W. Voos, 2005 .

Role of Mitochondrial Protein Quality Control in Oxidative Stress-induced Neurodegenerative Diseases.

G. Cenini, W. Voos, 2016, Current Alzheimer research.

Amyloid β-peptides interfere with mitochondrial preprotein import competence by a co-aggregation process

G. Cenini, W. Voos, Michael Bruderek, 2016, bioRxiv.

High aggregation sensitivity of mammalian mitochondrial elongation factor Tu (Tufm) as a sensor for organellar stress

M. Sylvester, W. Voos, Anne Wilkening, 2018 .

Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy

S. Przedborski, D. Becker, W. Voos, 2014, EMBO reports.

Mitochondrial GrpEIsPresent ina Complex withhsp7Oand Preproteins inTransit acrossMembranes

D. Ang, W. Voos, S. Laloraya, 1994 .

A J-protein is an essential subunit of the presequence translocase–associated protein import motor of mitochondria

N. Pfanner, A. Sickmann, Jan Dudek, 2003, The Journal of cell biology.