V. Chaudhary

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Recombinant toxins as novel therapeutic agents.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1992, Annual review of biochemistry.

Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL.

I. Pastan, D. Fitzgerald, S. Seetharam, 1991, The Journal of biological chemistry.

Allergens of Curvularia lunata during cultivation in different media.

N. Arora, B. Singh, V. Chaudhary, 1999, The Journal of allergy and clinical immunology.

Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv)

I. Pastan, D. Fitzgerald, V. Chaudhary, 1991, Molecular and cellular biology.

Expression, purification, and characterization of an anti-RBCFab-p24 fusion protein for hemagglutination-based rapid detection of antibodies to HIV in whole blood.

V. Chaudhary, Amita Gupta, 2002, Protein expression and purification.

SMALL SCALE EXPRESSION, SOLUBILIZATION AND CHARACTERIZATION OF CHIKUNGUNYA VIRUS STRUCTURAL PROTEINS

Sanjay Gupta, V. Chaudhary, Amita Gupta, 2014 .

Expression and purification of recombinant antigens of Mycobacterium tuberculosis for application in serodiagnosis.

A. Tyagi, S. Sharma, V. Chaudhary, 2005, Protein expression and purification.

Host interactions of Chandipura virus matrix protein.

Sanjay Gupta, V. Chaudhary, Amita Gupta, 2015, Acta tropica.

Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.

I. Pastan, M. Willingham, D. Fitzgerald, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors

R. Becker, R. Kini, C. Koh, 2021, Nature Communications.

Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1994, Blood.

Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma

I. Pastan, D. Fitzgerald, V. Chaudhary, 1994 .

Insertion of constant region domains of human IgG1 into CD4-PE40 increases its plasma half-life.

I. Pastan, S. Kasturi, V. Chaudhary, 1993, Molecular immunology.

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1990, The Journal of biological chemistry.

TGFα-anti-Tac(Fv)-PE40: A bifunctional toxin cytotoxic for cells with EGF or IL2 receptors

I. Pastan, V. Chaudhary, J. Batra, 1990 .

Anti-Tac(Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells.

I. Pastan, D. Fitzgerald, M. Gately, 1990, The Journal of biological chemistry.

A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin

T. Waldmann, I. Pastan, V. Chaudhary, 1989, Nature.

Cytotoxic activities of a fusion protein comprised of TGFα and Pseudomonas exotoxin

I. Pastan, S. Adhya, D. Fitzgerald, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cytotoxic activity of an interleukin 2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli.

I. Pastan, S. Adhya, D. Fitzgerald, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Network mapping among the functional domains of Chikungunya virus nonstructural proteins

S. Gulati, Sanjay Gupta, V. Chaudhary, 2014, Proteins.

Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain.

I. Pastan, S. Adhya, D. Fitzgerald, 1988, The Journal of biological chemistry.

A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin.

I. Pastan, V. Chaudhary, M. Gallo, 1990, Proceedings of the National Academy of Sciences of the United States of America.

IL2-PE664Glu, a new chimeric protein cytotoxic to human-activated T lymphocytes.

T. Waldmann, I. Pastan, R. Clark, 1990, The Journal of biological chemistry.

The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.

T. Waldmann, I. Pastan, M. Willingham, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Cytotoxic activity of a recombinant fusion protein between interleukin 4 and Pseudomonas exotoxin.

I. Pastan, V. Chaudhary, M. Ogata, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Mutagenesis of Pseudomonas exotoxin in identification of sequences responsible for the animal toxicity.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1990, The Journal of biological chemistry.

Functional analysis of domains II, Ib, and III of Pseudomonas exotoxin.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1989, The Journal of biological chemistry.

Activity of a recombinant fusion protein between transforming growth factor type alpha and Pseudomonas toxin.

I. Pastan, S. Adhya, D. Fitzgerald, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Recombinant CD4-Pseudomonas exotoxin hybrid protein displays HIV-specific cytotoxicity without affecting MHC class II-dependent functions.

I. Pastan, B. Moss, D. Fitzgerald, 1990, AIDS research and human retroviruses.

Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein

I. Pastan, B. Moss, T. Fuerst, 1988, Nature.

Identification of potential molecular associations between chikungunya virus non-structural protein 2 and human host proteins.

S. Gupta, S. Gulati, V. Chaudhary, 2017, Acta virologica.

Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds.

I. Pastan, D. Fitzgerald, S. Seetharam, 1993, Bioconjugate chemistry.

A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo.

Yogendra Pratap Singh, S. Leppla, Y. Singh, 1989, The Journal of biological chemistry.

A proper amino terminus of diphtheria toxin is important for cytotoxicity.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1991, Biochemical and biophysical research communications.

Domain II mutants of Pseudomonas exotoxin deficient in translocation.

I. Pastan, M. Willingham, S. Adhya, 1989, The Journal of biological chemistry.

from patients with chronic lymphocytic leukemia monoclonal antibody to the interleukin-2 receptor kill malignant cells Recombinant toxins containing the variable domains of the anti-Tac

I. Pastan, D. Fitzgerald, V. Chaudhary, 2011 .

Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1992, Blood.

Bifunctional recombinant fusion proteins for rapid detection of antibodies to both HIV-1 and HIV-2 in whole blood

V. Chaudhary, Amita Gupta, 2006, BMC biotechnology.

Recombinant fusion proteins for haemagglutination-based rapid detection of antibodies to HIV in whole blood.

S. Gupta, V. Chaudhary, A. Gupta, 2001, Journal of immunological methods.

A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunotoxins.

I. Pastan, M. Willingham, D. Fitzgerald, 1990, Proceedings of the National Academy of Sciences of the United States of America.

A Novel Helper Phage Enabling Construction of Genome-Scale ORF-Enriched Phage Display Libraries

Charanpreet Kaur, V. Chaudhary, Amita Gupta, 2013, PloS one.

Phage Display: a Molecular Fashion Show

A. Oppenheim, V. Chaudhary, Amita Gupta, 2005 .

Serogroup-reactive and type-specific detection of bluetongue virus antibodies using chicken scFvs in inhibition ELISAs.

V. Chaudhary, D. D. du Plessis, W. van Wyngaardt, 2005, Journal of virological methods.

Host–pathogen interactome analysis of Chikungunya virus envelope proteins E1 and E2

Sanjay Gupta, V. Chaudhary, Amita Gupta, 2015, Virus Genes.

Cytotoxic activity of an interleukin 6-Pseudomonas exotoxin fusion protein on human myeloma cells.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Cloning and expression of the recombinant FAb fragment of monoclonal antibody K1 that reacts with mesothelin present on mesotheliomas and ovarian cancers

I. Pastan, U. Brinkmann, P. Chowdhury, 1997, International journal of cancer.

In silico study of chikungunya polymerase, a potential target for inhibitors

Sanjay Gupta, Vandana Gupta, V. Chaudhary, 2019, VirusDisease.

Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia.

T. Waldmann, I. Pastan, V. Chaudhary, 1993, Leukemia.

Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors.

J. Weinstein, I. Pastan, B. Moss, 1990, Proceedings of the National Academy of Sciences of the United States of America.

CD4-Pseudomonas exotoxin hybrid protein blocks the spread of human immunodeficiency virus infection in vitro and is active against cells expressing the envelope glycoproteins from diverse primate immunodeficiency retroviruses.

I. Pastan, B. Moss, S. Chakrabarti, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Mutational analysis of domain I of Pseudomonas exotoxin. Mutations in domain I of Pseudomonas exotoxin which reduce cell binding and animal toxicity.

I. Pastan, S. Adhya, D. Fitzgerald, 1988, The Journal of biological chemistry.

Expression and purification of anthrax toxin protective antigen from Escherichia coli.

P. Swain, Y. Singh, V. Chaudhary, 1996, Protein expression and purification.

Phytochemicals as Antiviral Agents: Recent Updates

Vandana Gupta, V. Chaudhary, R. Gabrani, 2020, Plant-derived Bioactives.

Identification of Cross-Reactive Proteins amongst Different Curvularia Species

N. Arora, Bhanu Pratap Singh, V. Chaudhary, 2002, International Archives of Allergy and Immunology.

Host–pathogen interactome analysis of Chikungunya virus envelope proteins E1 and E2

Sanjay Gupta, V. Chaudhary, Amita Gupta, 2015, Virus Genes.

Whole-Blood Agglutination Assay for On-Site Detection of Human Immunodeficiency Virus Infection

V. Chaudhary, Amita Gupta, Amita Gupta, 2003, Journal of Clinical Microbiology.

Gag-derived proteins of HIV-1 isolates from Indian patients: cloning, expression, and purification of p17 of B- and C-subtypes.

V. Chaudhary, A. Gupta, S. Gupta, 2001, Protein expression and purification.

Pseudomonas exotoxin fusion proteins are potent immunogens for raising antibodies against P-glycoprotein.

I. Pastan, M. Gottesman, V. Chaudhary, 1991, BioTechniques.

High-density functional display of proteins on bacteriophage lambda.

I. Pastan, S. Adhya, V. Chaudhary, 2003, Journal of molecular biology.

Elucidating the Interacting Domains of Chandipura Virus Nucleocapsid Protein

Chakresh Kumar Jain, S. Gulati, Sanjay Gupta, 2013, Advances in virology.

Intraviral protein interactions of Chandipura virus

R. Sreejith, Sanjay Gupta, S. Sharma, 2012, Archives of Virology.

Expression and Characterization of Chandipura Virus Proteins

Sanjay Gupta, V. Chaudhary, Amita Gupta, 2011 .

Regular Article Expression and Characterization of Chandipura Virus Proteins

Sanjay Gupta, V. Chaudhary, Amita Gupta, 2011 .

Biotin-tagged proteins: Reagents for efficient ELISA-based serodiagnosis and phage display-based affinity selection

Charanpreet Kaur, V. Chaudhary, Amita Gupta, 2018, PloS one.

An efficient ORF selection system for DNA fragment libraries based on split beta-lactamase complementation

V. Chaudhary, G. Joshi, Amita Gupta, 2020, PloS one.

Interdomain hydrolysis of a truncated Pseudomonas exotoxin by the human immunodeficiency virus-1 protease.

I. Pastan, A. Tomasselli, R. Heinrikson, 1990, The Journal of biological chemistry.

Properties of chimeric toxins with two recognition domains: interleukin 6 and transforming growth factor alpha at different locations in Pseudomonas exotoxin.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1992, Bioconjugate chemistry.

Expression and purification of recombinant 38-kDa and Mtb81 antigens of Mycobacterium tuberculosis for application in serodiagnosis.

A. Tyagi, V. Chaudhary, Amita Gupta, 2005, Protein expression and purification.

Molecular cloning and characterization of chikungunya virus genes from indian isolate of 2006 Outbreak

S. Gupta, S. Sharma, V. Chaudhary, 2012 .

Gag-derived proteins of HIV-1 isolates from Indian patients: cloning, expression, and purification of p24 of B- and C-subtypes.

V. Chaudhary, A. Gupta, S. Gupta, 2000, Protein expression and purification.

Mapping interactions of Chikungunya virus nonstructural proteins.

R. Sreejith, Sanjay Gupta, S. Sharma, 2012, Virus research.

Rational design of a chimeric toxin: an intramolecular location for the insertion of transforming growth factor alpha within Pseudomonas exotoxin as a targeting ligand.

I. Pastan, D. Fitzgerald, V. Chaudhary, 1992, Bioconjugate chemistry.

Proteases from human immunodeficiency virus and avian myeloblastosis virus show distinct specificities in hydrolysis of multidomain protein substrates

I. Pastan, A. Tomasselli, I. Reardon, 1990, Journal of virology.

Challenges in Tuberculosis Diagnosis and Management: Recommendations of the Expert Panel

Sarman Singh, P. Sharma, V. Katoch, 2015, Journal of Laboratory Physicians.

Directed evolution of an anti-human red blood cell antibody

R. Bhat, V. Chaudhary, Amita Gupta, 2009, mAbs.

MAPPING OF HIV-1 GAG EPITOPES RECOGNIZED BY POLYCLONAL ANTIBODIES USING GENE-FRAGMENT PHAGE DISPLAY SYSTEM

V. Chaudhary, Amita Gupta, K. Arora, 2001, Preparative biochemistry & biotechnology.

Emulsion PCR made easy.

V. Chaudhary, Amita Gupta, Vaishali Verma, 2020, BioTechniques.

Role of domain II of Pseudomonas exotoxin in the secretion of proteins into the periplasm and medium by Escherichia coli.

Y H Xu, I. Pastan, S. Adhya, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity.

K. Klimpel, S. Leppla, Y. Singh, 1991, The Journal of biological chemistry.

Characterization of a cellular protease that cleaves Pseudomonas exotoxin

V. Chaudhary, C. Fryling, M. Ogata, 1992, Infection and immunity.

Anti-Tac(Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells.

I. Pastan, M. Gately, V. Chaudhary, 1990, The Journal of biological chemistry.