D. Frendewey

发表

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses

G. Yancopoulos, N. Gale, S. Stevens, 2007, Nature Biotechnology.

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

Michael Morse, J. Rinn, Manolis Kellis, 2013, eLife.

The mammalian gene function resource: the international knockout mouse consortium

Steve D. M. Brown, Hamsa D. Tadepally, Mark W. Moore, 2012, Mammalian Genome.

Modeling the Initiation and Progression of Human Acute Leukemia in Mice

Nikolaus Rajewsky, David Frendewey, Klaus Rajewsky, 2022 .

Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants.

J. Potashkin, D. Frendewey, 1989, Nucleic acids research.

Schizosaccharomyces U6 genes have a sequence within their introns that matches the B box consensus of tRNA internal promoters.

M. Gillespie, J. Potashkin, D. Frendewey, 1990, Nucleic acids research.

Long form of latent TGF-β binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling

A. Murphy, G. Yancopoulos, D. Rifkin, 2007 .

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

A. F. Stewart, L. Macdonald, A. Murphy, 2003, Nature Biotechnology.

The loss-of-allele assay for ES cell screening and mouse genotyping.

A. Murphy, G. Yancopoulos, D. Frendewey, 2010, Methods in enzymology.

Pac1p, an RNase III homolog, is required for formation of the 3' end of U2 snRNA in Schizosaccharomyces pombe.

D. Frendewey, D. Zhou, S. M. Lobo Ruppert, 1999, RNA.

Pac1 ribonuclease of Schizosaccharomyces pombe.

D. Frendewey, G. Rotondo, 2001, Methods in enzymology.

Conditionals by inversion provide a universal method for the generation of conditional alleles

Joseph M. Cruz, P. Lengyel, A. Murphy, 2013, Proceedings of the National Academy of Sciences.

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

F. Alt, L. Macdonald, A. Murphy, 2014, Proceedings of the National Academy of Sciences.

Loss of tRNA 5-methyluridine methyltransferase and pseudouridine synthetase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli.

I. I. Kaiser, D. Frendewey, V. Moore, 1982, Biochimica et biophysica acta.

Specific incorporation of 5-fluorocytidine into Escherichia coli RNA.

I. I. Kaiser, D. Frendewey, D. M. Kladianos, 1985, Biochimica et biophysica acta.

Effects of 5-fluorouracil on base modification in Escherichia coli tRNA.

I. I. Kaiser, D. Frendewey, 1979, Biochemistry.

Ribonuclease activity and RNA binding of recombinant human Dicer

B. Samuelsson, O. Rådmark, P. Provost, 2002, The EMBO journal.

Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs

J. Rinn, G. Yancopoulos, G. Droguett, 2015, PloS one.

The long non-coding RNAs : a new ( p ) layer in the “ dark matter ”

Michael Morse, J. Rinn, Manolis Kellis, 2014 .

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

A. F. Stewart, L. Macdonald, A. Murphy, 2003, Nature Biotechnology.

Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice

Yurong Xin, E. Chiao, B. Zambrowicz, 2021, Nature Communications.

Regulation of the Germinal Center Response by MicroRNA-155

N. Rajewsky, J. Kutok, K. Rajewsky, 2007, Science.

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Pingfang Liu, David Frendewey, Caitlin Kennedy, 2006, Cell.

Functions of the Abundant U-snRNPs

J. Steitz, D. Black, A. Krämer, 1988 .

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

David Frendewey, W. Keller, D. Frendewey, 1985, Cell.

Accurate in vitro splicing of two pre‐mRNA plant introns in a HeLa cell nuclear extract.

J. Brown, D. Frendewey, G. Feix, 1986, The EMBO journal.

A mutation in a single gene of Schizosaccharomyces pombe affects the expression of several snRNAs and causes defects in RNA processing.

J. Potashkin, D. Frendewey, 1990, The EMBO journal.

Pre‐mRNA splicing mutants of Schizosaccharomyces pombe.

J. Potashkin, D. Frendewey, R. Li, 1989, The EMBO journal.

Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe.

D. Frendewey, G Rotondo, D Frendewey, 1996, Nucleic acids research.

Producing fully ES cell-derived mice from eight-cell stage embryo injections.

G. Yancopoulos, W. Poueymirou, W. Auerbach, 2010, Methods in enzymology.

VelociMouse: fully ES cell-derived F0-generation mice obtained from the injection of ES cells into eight-cell-stage embryos.

G. Yancopoulos, W. Poueymirou, W. Auerbach, 2009, Methods in molecular biology.

K. Gould, W. McDonald, R. Ohi, 1999, Molecular and Cellular Biology.

Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast

T. Tani, D. Frendewey, Noriko Sasaki-Haraguchi, 2015, PloS one.

Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants

J. Potashkin, T. Humphrey, D. Frendewey, 1998, Current Genetics.

Mutations in the SF1-U2AF59-U2AF23 Complex Cause Exon Skipping in Schizosaccharomyces pombe*

T. Tani, D. Frendewey, T. Andoh, 2007, Journal of Biological Chemistry.

Poueymirou, W.T. et al. F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses. Nat. Biotechnol. 25, 91-99

G. Yancopoulos, N. Gale, S. Stevens, 2007 .

Generation of fertile and fecund F0 XY female mice from XY ES cells

C. Siao, G. Yancopoulos, J. Kuno, 2015, Transgenic Research.

Ltbp1Lis focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution

G. Droguett, D. Frendewey, P. Cowin, 2013, Breast Cancer Research.

Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease

Marc Gillespie, David Frendewey, M. Gillespie, 1995, Molecular and General Genetics MGG.

A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicase.

Y. Ohshima, T. Tani, S. Urushiyama, 1996, Molecular biology of the cell.

The Schizosaccharomyces pombe sup3‐i suppressor recognizes ochre, but not amber codons in vitro and in vivo.

D. Söll, H. Hottinger, J. Kohli, 1984, The EMBO journal.

Two RNA species co‐purify with RNase P from the fission yeast Schizosaccharomyces pombe.

B. Cherayil, D. Söll, S. Nishikawa, 1986, The EMBO journal.

Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution

G. Droguett, D. Frendewey, P. Cowin, 2013, Breast Cancer Research.

A single base change in the intron of a serine tRNA affects the rate of RNase P cleavage in vitro and suppressor activity in vivo in Saccharomyces cerevisiae.

D. Söll, M. Nichols, J. Schaack, 1986, The Journal of biological chemistry.

Substrate structure requirements of the Pac1 ribonuclease from Schizosaccharmyces pombe.

D. Frendewey, G Rotondo, J Y Huang, 1997, RNA.

The mammalian gene function resource: the international knockout mouse consortium

Hamsa D. Tadepally, C. Bult, J. Eppig, 2012, Mammalian Genome.

VelociMouse: fully ES cell-derived F0-generation mice obtained from the injection of ES cells into eight-cell-stage embryos.

G. Yancopoulos, W. Poueymirou, W. Auerbach, 2009, Methods in molecular biology.