J. Lyon

发表

Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites.

W. Ballou, W. Leitner, M. Seguin, 1997, Journal of immunology.

Assignment of the carbon-13 nuclear magnetic resonance spectrum of folic acid.

J. Lyon, P. D. Ellis, R. B. Dunlap, 1973, Biochemistry.

Merozoite surface protein-1 epitopes recognized by antibodies that inhibit Plasmodium falciparum merozoite dispersal.

A. Thomas, J. Lyon, J. Chulay, 1997, Molecular and biochemical parasitology.

New World monkey efficacy trials for malaria vaccine development: critical path or detour?

C. Ockenhouse, K. Kester, J. Lyon, 2001, Trends in parasitology.

Phase 1 randomized double-blind safety and immunogenicity trial of Plasmodium falciparum malaria merozoite surface protein FMP1 vaccine, adjuvanted with AS02A, in adults in western Kenya.

V. A. Stewart, Janet Wittes, J. Wittes, 2007, Vaccine.

Phase I safety and immunogenicity trial of FMP1/AS02A, a Plasmodium falciparum MSP-1 asexual blood stage vaccine.

Joe D. Cohen, O. Ofori-Anyinam, C. Ockenhouse, 2006, Vaccine.

Monoclonal antibody characterization of the 195-kilodalton major surface glycoprotein of Plasmodium falciparum malaria schizonts and merozoites: identification of additional processed products and a serotype-restricted repetitive epitope.

J. Haynes, C. Haidaris, J. Lyon, 1987, Journal of immunology.

Development and pre-clinical analysis of a Plasmodium falciparum Merozoite Surface Protein-1(42) malaria vaccine.

J. Haynes, Joe D. Cohen, C. Ockenhouse, 2003, Molecular and biochemical parasitology.

Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP1(42) formulated with novel adjuvants or with alum.

Joe D. Cohen, E. Angov, S. Pichyangkul, 2004, Vaccine.

The Clinical-Grade 42-Kilodalton Fragment of Merozoite Surface Protein 1 of Plasmodium falciparum Strain FVO Expressed in Escherichia coli Protects Aotus nancymai against Challenge with Homologous Erythrocytic-Stage Parasites

J. Barnwell, A. Holder, E. Bergmann-Leitner, 2005, Infection and Immunity.

Heterologous prime-boost immunization in rhesus macaques by two, optimally spaced particle-mediated epidermal deliveries of Plasmodium falciparum circumsporozoite protein-encoding DNA, followed by intramuscular RTS,S/AS02A.

V. A. Stewart, Joe D. Cohen, S. Pichyangkul, 2006, Vaccine.

C3d binding to the circumsporozoite protein carboxy-terminus deviates immunity against malaria.

E. Bergmann-Leitner, E. Angov, G. Tsokos, 2005, International immunology.

Gel electrophoresis as a means of detecting ternary complex formation of thymidylate synthetase

J. Lyon, R. B. Dunlap, J. Aull, 1974 .

Separation, identification, and stoichiometry of the ternary complexes of thymidylate synthetase.

J. Lyon, R. B. Dunlap, J. Aull, 1974, Archives of biochemistry and biophysics.

Inhibitory and blocking monoclonal antibody epitopes on merozoite surface protein 1 of the malaria parasite Plasmodium falciparum.

A. Holder, J. Feeney, C. Ockenhouse, 2001, Journal of molecular biology.

Genetic Vaccination against Malaria Infection by Intradermal and Epidermal Injections of a Plasmid Containing the Gene Encoding thePlasmodium berghei Circumsporozoite Protein

W. Leitner, J. Lyon, S. Scheiblhofer, 2000, Infection and Immunity.

Process Analysis of Liver-Stage Antigen 1, a Preerythrocyte-Stage Protein-Based Vaccine for Plasmodium falciparum

E. Angov, J. Lyon, D. Lanar, 2005 .

Protection Induced by Plasmodium falciparum MSP142 Is Strain-Specific, Antigen and Adjuvant Dependent, and Correlates with Antibody Responses

M. Fay, J. Barnwell, E. Bergmann-Leitner, 2008, PloS one.

Allelic forms of gp195, a major blood-stage antigen of Plasmodium falciparum, are expressed in liver stages

A. Szarfman, R. Carter, J. Lyon, 1988, The Journal of experimental medicine.

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

V. A. Stewart, J. Wittes, M. Thera, 2005, Vaccine.

Transport of an Mr 300,000 Plasmodium falciparum Protein (Pf EMP 2) from the Intraerythrocytic Asexual Parasite to the Cytoplasmic Face of the Host Cell Membrane

A. Saul, J. Lyon, S. Aley, 2003 .

Use of fluorodinitrobenzene to identify monoclonal antibodies which are suitable for conjugation to periodate-oxidized horseradish peroxidase.

T. Burkot, R. Wirtz, J. Lyon, 1985, Journal of immunological methods.

Specificities of antibodies that inhibit merozoite dispersal from malaria-infected erythrocytes.

A. Thomas, J. Lyon, J. Chulay, 1989, Molecular and biochemical parasitology.

Inhibition of nitric oxide induction from avian macrophage cell lines by influenza virus.

V. Hinshaw, J. Lyon, 1993, Avian diseases.

Blood Stage Malaria Vaccine Eliciting High Antigen-Specific Antibody Concentrations Confers No Protection to Young Children in Western Kenya

V. A. Stewart, W. Ripley Ballou, Janet Wittes, 2009, PloS one.

Formation of ternary complexes of thymidylate synthetase as followed by absorbance, fluorescence, and circular dichroic spectra and gel electrophoresis.

J. Lyon, R. B. Dunlap, J. Aull, 1976, The Journal of biological chemistry.

Membrane lipid composition modulates the binding specificity of a monoclonal antibody against liposomes.

C. Alving, J. Lyon, B. Banerji, 1982, Biochimica et biophysica acta.

Use of monoclonal antibody to immunochemically characterize variant-specific surface coat glycoprotein from Trypanosoma rhodesiense.

J. M. Pratt, B. P. Doctor, J. Lyon, 1981, Journal of immunology.

Assignment of the carbon-13 nuclear magnetic resonance spectra of selected folates

J. Lyon, P. D. Ellis, R. B. Dunlap, 1975 .

Removal of the circumsporozoite protein (CSP) glycosylphosphatidylinositol signal sequence from a CSP DNA vaccine enhances induction of CSP‐specific Th2 type immune responses and improvesprotection against malaria infection

W. Leitner, J. Lyon, S. Scheiblhofer, 2001, European journal of immunology.

Two approximately 300 kilodalton Plasmodium falciparum proteins at the surface membrane of infected erythrocytes.

E. Rock, J. Barnwell, W. Maloy, 1988, Molecular and biochemical parasitology.

Localization of the major Plasmodium falciparum glycoprotein on the surface of mature intraerythrocytic trophozoites and schizonts.

J. Barnwell, J. Haynes, L. Miller, 1984, Molecular and biochemical parasitology.

Sequence comparison of allelic forms of the Plasmodium falciparum merozoite surface antigen MSA2.

A. Thomas, J. Lyon, J. M. Carter, 1990, Molecular and biochemical parasitology.

Blood Stage Antigen Genes of Plasmodium falciparium

J. Weber, J. Lyon, D. Camus, 1987 .

Heterologous Protein Expression Is Enhanced by Harmonizing the Codon Usage Frequencies of the Target Gene with those of the Expression Host

Randall L. Kincaid, R. Kincaid, E. Angov, 2008, PloS one.

Phosphate-binding specificities of monoclonal antibodies against phosphoinositides in liposomes.

C. Alving, F. Roerdink, J. Lyon, 1984, Molecular immunology.

Identification of a subpopulation of immune Nigerian adult volunteers by antibodies to the circumsporozoite protein of Plasmodium falciparum.

R. Wirtz, J. Lyon, O. Sodeinde, 1998, The American journal of tropical medicine and hygiene.

Primary structure of a Plasmodium falciparum malaria antigen located at the merozoite surface and within the parasitophorous vacuole.

J. Weber, J. Lyon, J. Chulay, 1988, The Journal of biological chemistry.

Plasmodium berghei: cloning of the circumsporozoite protein gene.

J. Weber, R. Wirtz, W. Maloy, 1987, Experimental parasitology.

Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca2+ entry channel.

R. Stevenson, C. Schwartz, K. Sossey-Alaoui, 1999, Genomics.

Critical evaluation of different methods for measuring the functional activity of antibodies against malaria blood stage antigens.

E. Bergmann-Leitner, E. Angov, C. Long, 2006, The American journal of tropical medicine and hygiene.

Epitope map and processing scheme for the 195,000-dalton surface glycoprotein of Plasmodium falciparum merozoites deduced from cloned overlapping segments of the gene.

J. Weber, J. Haynes, J. Lyon, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Safety and Reactogenicity of an MSP-1 Malaria Vaccine Candidate: A Randomized Phase Ib Dose-Escalation Trial in Kenyan Children

V. A. Stewart, J. Wittes, B. Ogutu, 2006, PLoS clinical trials.

Variation in the gene encoding a major merozoite surface antigen of the human malaria parasite Plasmodium falciparum.

J. Weber, J. Lyon, W. M. Leininger, 1986, Nucleic acids research.

Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface when schizonts mature in the presence of protease inhibitors.

J. Haynes, J. Lyon, 1986, Journal of immunology.

Monoclonal antibody characterization of Plasmodium falciparum antigens in immune complexes formed when schizonts rupture in the presence of immune serum.

C. Atkinson, J. Haynes, J. Lyon, 1987, Journal of immunology.

Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface by antibodies when schizonts mature in the presence of growth inhibitory immune serum.

J. Haynes, J. Lyon, J. Chulay, 1986, Journal of immunology.

T lymphocytes from volunteers immunized with irradiated Plasmodium falciparum sporozoites recognize liver and blood stage malaria antigens.

I. Schneider, W. Ballou, J. Lyon, 1995, Journal of immunology.

Use of synthetic and recombinant peptides in the study of host-parasite interactions in the malarias.

S. Hoffman, R. Howard, W. Ballou, 1987, The American journal of tropical medicine and hygiene.

Transport of an Mr approximately 300,000 Plasmodium falciparum protein (Pf EMP 2) from the intraerythrocytic asexual parasite to the cytoplasmic face of the host cell membrane

E. Rock, K. Marsh, A. Saul, 1987, The Journal of cell biology.

Export of PlasmodiumFalciparum Proteins to the Host Erythrocyte Membrane: Special Problems of Protein Trafficking and Topogenesis

J. Lyon, R. J. Howard, M. Aikawa, 1987 .

Passive transfer of growth-inhibitory antibodies raised against yeast-expressed recombinant Plasmodium falciparum merozoite surface protein-1(19).

J. K. Moch, J. Haynes, D. Kaslow, 1998, The American journal of tropical medicine and hygiene.

Process Development and Analysis of Liver-Stage Antigen 1, a Preerythrocyte-Stage Protein-Based Vaccine for Plasmodium falciparum

E. Angov, J. Lyon, D. Lanar, 2005, Infection and Immunity.

Characterization of gp195 processed products purified from Plasmodium falciparum culture supernates.

J. Haynes, J. Lyon, C. Diggs, 1987, Molecular and biochemical parasitology.

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

V. A. Stewart, J. Wittes, M. Thera, 2005, Vaccine.