I. Clarke

发表

Identification of human brain tumour initiating cells

R. Henkelman, C. Hawkins, J. Squire, 2004, Nature.

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

Gary D Bader, Trevor J Pugh, S. Scherer, 2014, Nature.

A human brain tumor-derived PDGFR-α deletion mutant is transforming

P. Dirks, I. Clarke, P B Dirks, 2003, Oncogene.

Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity

Gary D Bader, S. Scherer, A. C. Lionel, 2015, Proceedings of the National Academy of Sciences.

SINGLE CELL DERIVED CLONAL ANALYSIS OF HUMAN GLIOBLASTOMA LINKS FUNCTIONAL AND GENOMIC HETEROGENEITY

Gary D Bader, S. Scherer, A. C. Lionel, 2014, Neuro-Oncology.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Gary D Bader, M. Bernstein, M. Lupien, 2017, Cell stem cell.

Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors.

V. P. Collins, S. Scherer, P. Boutros, 2009, Cancer cell.

IQGAP1 protein specifies amplifying cancer cells in glioblastoma multiforme.

F. Ducray, J. Honnorat, A. Jouvet, 2006, Cancer research.

Can be Safely Targeted for Telomerase Inhibition Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance

C. Harley, D. Kaplan, P. Dirks, 2010 .

MECP2 Isoform-Specific Vectors with Regulated Expression for Rett Syndrome Gene Therapy

P. Dirks, P. Pasceri, J. Ellis, 2009, PloS one.

Murine xenogeneic immune responses to the human testis: a presumed immune-privileged tissue.

P. Merguerian, I. Clarke, M. Kushida, 2000, Transplantation.

Identification of a cancer stem cell in human brain tumors.

Cynthia Hawkins, C. Hawkins, J. Squire, 2003, Cancer research.

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.

Mark Bernstein, Roslin Russell, Davide Danovi, 2009, Cell stem cell.

Chemical genetics reveals a complex functional ground state of neural stem cells.

Mike Tyers, Phedias Diamandis, Jan Wildenhain, 2007, Nature chemical biology.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Gary D Bader, M. Bernstein, M. Lupien, 2017, Cell stem cell.

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.

J. Dick, M. Bernstein, S. Pfister, 2015, Cancer cell.

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.

Gary D Bader, M. Tyers, M. Bernstein, 2016, Cancer cell.

Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma.

K. Graham, C. Hui, P. Dirks, 2009, Cancer research.

ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.

Aaron S. Gajadhar, J. Rutka, C. Hawkins, 2014, Cancer discovery.

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

N. Batada, M. Bernstein, S. Angers, 2019, Genes & development.

Cancer stem cells in nervous system tumors

P. Dirks, Sheila K Singh, I. Clarke, 2004, Oncogene.

A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas

Aaron S. Gajadhar, K. Aldape, G. Fuller, 2011, The Journal of experimental medicine.

Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma.

Steven J. M. Jones, Gary D Bader, Richard A. Moore, 2014, Cancer cell.

Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance and Can be Safely Targeted for Telomerase Inhibition

C. Harley, D. Kaplan, P. Dirks, 2010, Clinical Cancer Research.

A tumorigenic MLL-homeobox network in human glioblastoma stem cells.

J. Ho, M. Gallo, P. Dirks, 2013, Cancer research.

Tumor and Stem Cell Biology A Tumorigenic MLL-Homeobox Network in Human Glioblastoma Stem Cells

J. Ho, M. Gallo, P. Dirks, 2012 .

T cells are necessary and critical for xenograft rejection in new concordant cardiac xenotransplant model.

I. Clarke, M. Kushida, M. Obatake, 1999, Transplantation.

Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function

B. Ciruna, F. Sicheri, P. Dirks, 2011, The EMBO journal.

A human brain tumor-derived PDGFR-alpha deletion mutant is transforming.

P. Dirks, I. Clarke, P B Dirks, 2003, Oncogene.

Brain Cancer Stem Cells: A Level Playing Field

Austin G Smith, P. Dirks, S. Pollard, 2009 .

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.

R. Russell, M. Bernstein, S. Stricker, 2009, Cell stem cell.

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.

J. Dick, M. Bernstein, S. Pfister, 2015, Cancer Cell.

ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.

Aaron S. Gajadhar, J. Rutka, C. Hawkins, 2014, Cancer Discovery.

Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function

B. Ciruna, F. Sicheri, P. Dirks, 2011, EMBO Journal.