K. Hsiao

发表

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

S. Younkin, G. Cole, K. Hsiao, 1996, Science.

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

J. Hardy, S. Younkin, C. Eckman, 1998, Nature Medicine.

Scrapie prion protein contains a phosphatidylinositol glycolipid

Stanley B. Prusiner, S. Prusiner, D. Borchelt, 1987, Cell.

Caveolin-3 Upregulation Activates β-Secretase–Mediated Cleavage of the Amyloid Precursor Protein in Alzheimer’s Disease

I. Kanazawa, T. Iwatsubo, B. Trapp, 1999, The Journal of Neuroscience.

Human Slow Infections Caused by Prions

S. Prusiner, D. Kingsbury, D. Bredesen, 1989 .

Strain dependent and invariant features of transgenic mice expressing Alzheimer amyloid precursor proteins.

K. Hsiao, Karen Hsiao, 1998, Progress in brain research.

Transgenic mice expressing Alzheimer amyloid precursor proteins

K. Hsiao, 1998, Experimental Gerontology.

The Genetics and Transgenetics of Human Prion Disease

K. Hsiao, 1994, Annals of the New York Academy of Sciences.

Human prion diseases

S. Prusiner, K. Hsiao, 1994, Annals of neurology.

Genetics of prion infections.

S. Prusiner, D. Westaway, G. Carlson, 1991, Trends in genetics : TIG.

Spontaneous Neurodegeneration in Transgenic Mice with Prion Protein Codon 101 Proline → Leucine Substitution a

S. Prusiner, S. DeArmond, D. Foster, 1991, Annals of the New York Academy of Sciences.

Inherited human prion diseases

S. Prusiner, K. Hsiao, 1990, Neurology.

Prion protein gene expression in cultured cells.

S. Prusiner, D. Bredesen, M. Scott, 1988, Protein engineering.

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice

T. Bliss, B. Hyman, P. Chapman, 1999, Nature Neuroscience.

INSERTION IN PRION PROTEIN GENE IN FAMILIAL CREUTZFELDT-IAKOB DISEASE

T. Crow, S. Prusiner, J. Collinge, 1989, The Lancet.

Induction of NADPH cytochrome P450 reductase by the Alzheimer β‐protein. Amyloid as a ‘foreign body’

Mark A. Smith, J. Ghiso, K. Hsiao, 2001, Journal of neurochemistry.

Microglial response to amyloid plaques in APPsw transgenic mice.

B. Hyman, G. Cole, S. Frautschy, 1998, The American journal of pathology.

Regulation and genetic control of brain amyloid

S. Prusiner, D. Price, C. Masters, 1991, Brain Research Reviews.

D. Borchelt, D. Price, C. Iadecola, 1995, Neuron.

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

D. Borchelt, C. Iadecola, S. Younkin, 1999, Nature Neuroscience.

APPSW Transgenic Mice Develop Age‐related Aβ Deposits and Neuropil Abnormalities, but no Neuronal Loss in CA1

B. Hyman, M. Irizarry, K. Hsiao, 1997, Journal of neuropathology and experimental neurology.

Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome

Jurg Ott, Mark Poulter, Harry F. Baker, 1989, Nature.

Amyloid‐β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

M. Tabaton, Mark A. Smith, K. Hirai, 1998, Journal of neurochemistry.

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

S. Prusiner, D. Borchelt, D. Kingsbury, 1988, Journal of virology.

Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene

S. Prusiner, B. Ghetti, T. Foroud, 1992, Nature Genetics.

A prion protein variant in a family with the telencephalic form of Gerstmann‐Sträussler‐Scheinker syndrome

G. Schellenberg, S. Prusiner, T. Bird, 1991, Neurology.

Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.

S. Prusiner, J. Collinge, S. DeArmond, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles

S. Prusiner, B. Ghetti, M. Farlow, 1992, Nature Genetics.

Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease.

S. Prusiner, Z. Meiner, R. Gabizon, 1991, The New England journal of medicine.

Prions Causing Transmissible Neurodegenerative Diseases

S. Prusiner, K. Hsiao, 1990 .

Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.

S. Prusiner, S. DeArmond, M. Scott, 1994, Proceedings of the National Academy of Sciences of the United States of America.

From prion diseases to Alzheimer's disease.

K. Hsiao, 1997, Journal of neural transmission. Supplementum.

Behavioral Changes in Transgenic Mice Expressing Both Amyloid Precursor Protein and Presenilin-1 Mutations: Lack of Association with Amyloid Deposits

K. Duff, D. Morgan, K. Hsiao, 1999, Behavior genetics.

Increased Susceptibility to Ischemic Brain Damage in Transgenic Mice Overexpressing the Amyloid Precursor Protein

C. Iadecola, S. Younkin, C. Eckman, 1997, The Journal of Neuroscience.

Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.

D. Borchelt, S. Younkin, S. Turner, 1997, Human molecular genetics.

Understanding the Biology and Molecular Pathogenesis of Alzheimer’s Disease in Transgenic Mice Expressing Amyloid Precursor Proteins

K. Hsiao, 1997 .

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.

M. Smith, K. Hsiao, M. Pappolla, 1998, The American journal of pathology.

Neurotoxicity of the prion protein

K. Hsiao, J. Diedrich, 1994, Neurobiology of Aging.

Understanding the biology of β-amyloid precursor proteins in transgenic mice

K. Hsiao, 1995, Neurobiology of Aging.

Spontaneous neurodegeneration in transgenic mice with mutant prion protein

S. Prusiner, S. DeArmond, M. Scott, 1990, Science.

Human prion diseases

S. Prusiner, K. Hsiao, 1994, Annals of neurology.