D. Brenneman

发表

A Glia-Derived Signal Regulating Neuronal Differentiation

Shiaoping C. Zhu, I. Gozes, O. Blondel, 2000, The Journal of Neuroscience.

Small-Molecule Anticonvulsant Agents with Potent In Vitro Neuroprotection and Favorable Drug-Like Properties

D. Brenneman, A. Reitz, Garry R. Smith, 2014, Journal of Molecular Neuroscience.

Pharmaceutical VIP: prospects and problems.

I. Gozes, D. Brenneman, J. M. Hill, 1999, Current medicinal chemistry.

Levels of mRNA coding for α-, β- and γ-synuclein in the brains of newborn, juvenile, and adult rats

S. Ilyin, A. Pinhasov, D. Brenneman, 2007, Journal of Molecular Neuroscience.

Vasoactive Intestinal Peptide Regulates Embryonic Growth Through the Action of Activity‐dependent Neurotrophic Factor

P. Gressens, G. Glazner, I. Gozes, 1999, Annals of the New York Academy of Sciences.

IGF-I as a mediator of VIP/activity-dependent neurotrophic factor-stimulated embryonic growth.

I. Gozes, D. Brenneman, J. M. Hill, 2001, Endocrinology.

Alteration of catecholamine uptake in cerebral cortex from rats fed a saturated fat diet

D. Brenneman, C. Rutledge, 1979, Brain Research.

Neuropeptides as growth and differentiation factors in general and VIP in particular

I. Gozes, D. Brenneman, 2007, Journal of Molecular Neuroscience.

Activity-dependent neurotrophic factor (ADNF)

I. Gozes, D. Brenneman, 2007, Journal of Molecular Neuroscience.

Vasoactive Intestinal Peptide: From Molecular Genetics to Neurotropism

I. Gozes, D. Brenneman, 1993 .

Spontaneous electrical activity regulates vasoactive intestinal peptide expression in dissociated spinal cord cell cultures.

D. Agoston, I. Gozes, L. Eiden, 1991, Brain research. Molecular brain research.

Vasoactive intestinal peptide in the brain of a mouse model for Down syndrome

D. Brenneman, A. Ades, L. Crnic, 2003, Experimental Neurology.

NAP, a Femtomolar-Acting Peptide, Protects the Brain Against Ischemic Injury by Reducing Apoptotic Death

I. Gozes, H. Ovadia, D. Brenneman, 2002, Stroke.

A femtomolar-acting neuroprotective peptide.

I. Gozes, D. Brenneman, 1996, The Journal of clinical investigation.

Activity‐Dependent Neurotrophic Factor Peptide (ADNF9) Protects Neurons Against Oxidative Stress‐Induced Death

M. Mattson, A. Dresse, G. Glazner, 1999, Journal of neurochemistry.

Severe microcephaly induced by blockade of vasoactive intestinal peptide function in the primitive neuroepithelium of the mouse.

P. Gressens, I. Gozes, D. Brenneman, 1994, The Journal of clinical investigation.

A new concept in the pharmacology of neuroprotection

I. Gozes, D. Brenneman, 2000, Journal of Molecular Neuroscience.

Pharmacological Effects on Ceroid Lipofuscin and Neuronal Structure in Cln3∆ex7/8 Mouse Brain Cultures

D. Brenneman, D. Pearce, A. Kovács, 2017, Journal of Molecular Neuroscience.

(N-stearyl, norleucine17) VIP hybrid inhibits the growth of pancreatic cancer cell lines.

T. Moody, I. Gozes, D. Brenneman, 1999, Life sciences.

Vasoactive intestinal peptide shortens both G1 and S phases of neural cell cycle in whole postimplantation cultured mouse embryos

P. Gressens, P. Evrard, D. Brenneman, 1998, The European journal of neuroscience.

Different levels of γ‐synuclein mRNA in the cerebral cortex of dominant, neutral and submissive rats selected in the competition test

S. Ilyin, D. Brenneman, E. Malatyńska, 2004, Genes, brain, and behavior.

Cathepsins B and L Differentially Regulate Amyloid Precursor Protein Processing

D. Brenneman, Donna M Klein, K. Felsenstein, 2009, Journal of Pharmacology and Experimental Therapeutics.

Activity-dependent neuroprotective protein: a novel gene essential for brain formation.

A. Goldsweig, I. Gozes, A. Pinhasov, 2003, Brain research. Developmental brain research.

Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity

K. Sulik, D. Brenneman, M. E. Charness, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the hyperlipidemia in mice bearing the Ehrlich ascites tumor.

S. Mathur, A. A. Spector, D. Brenneman, 1975, European journal of cancer.

The increased proliferation of cultured neuroblastoma cells treated with vasoactive intestinal peptide is enhanced by simultaneous inhibition of neutral endopeptidase

I. Gozes, D. Brenneman, A. Iaina, 2002, Regulatory Peptides.

Neuroprotection: A comparative view of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide

D. Brenneman, 2007, Peptides.

Neuropeptide Regulation of Mitosis

T. Moody, I. Gozes, G. Lilling, 1994, Annals of the New York Academy of Sciences.

Inhibition of murine embryonic growth by human immunodeficiency virus envelope protein and its prevention by vasoactive intestinal peptide and activity-dependent neurotrophic factor.

G. Glazner, I. Gozes, D. Brenneman, 1997, The Journal of clinical investigation.

Maternal vasoactive intestinal peptide and the regulation of embryonic growth in the rodent.

G. Glazner, S. Stanziale, D. Brenneman, 1996, The Journal of clinical investigation.

VIP Regulation of Embryonic Growth

G. Glazner, D. Brenneman, Joannam . Hill, 1996, Annals of the New York Academy of Sciences.

Activity-dependent neurotrophic factor: a potent regulator of embryonic growth and development

P. Gressens, G. Glazner, I. Gozes, 1999, Anatomy and Embryology.

Growth factor function of vasoactive intestinal peptide in whole cultured mouse embryos

P. Gressens, I. Gozes, D. Brenneman, 1993, Nature.

Effect of dietary fat saturation on acylcoenzyme A:-cholesterol acyltransferase activity of Ehrlich cell microsomes.

A. A. Spector, D. Brenneman, T. Kaduce, 1977, Journal of lipid research.

Activity-dependent neurotrophic factor: structure-activity relationships of femtomolar-acting peptides.

I. Gozes, D. Brenneman, M. Fridkin, 1998, The Journal of pharmacology and experimental therapeutics.

[3H]-tetrodotoxin binding in neuronal and non-neuronal spinal cord cultures.

M. Lazdunski, D. Brenneman, A. Lombet, 1986, Biochemical and biophysical research communications.

[H3]-nitrendipine binding in non-neuronal cell cultures.

G. Foster, D. Brenneman, M. Litzinger, 1986, Biochemical and biophysical research communications.

Subcellular localization and secretion of activity-dependent neuroprotective protein in astrocytes.

I. Gozes, D. Brenneman, S. Mandel, 2004, Neuron glia biology.

TTX displacement of [H3]-nitrendipine binding in developing spinal cord neurons.

D. Brenneman, M. Litzinger, 1984, Biochemical and biophysical research communications.

Vasoactive intestinal peptide inhibits cytokine production in T lymphocytes through cAMP-dependent and cAMP-independent mechanisms

I. Gozes, D. Ganea, D. Brenneman, 1999, Regulatory Peptides.

Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures: relevance to neuroprotection in Parkinson's disease 1 This manuscript is based on a poster presented at the Brain Research Interactive Symposium on “Neuropeptides at the Millennium”, Miami, October 1999. 1

E. Melamed, D. Offen, I. Gozes, 2000, Brain Research.

Regulation of fatty acid biosynthesis in Ehrlich cells by ascites tumor plasma lipoproteins

A. A. Spector, D. Brenneman, R. Mcgee, 2006, Lipids.

Preventive Treatment of Alzheimer’s Disease

I. Gozes, A. Bardea, D. Brenneman, 1998 .

Antiserum to activity-dependent neurotrophic factor produces neuronal cell death in CNS cultures: immunological and biological specificity.

I. Gozes, D. Brenneman, Y. Gozes, 1997, Brain research. Developmental brain research.

Prevention of activity-dependent neuronal death: vasoactive intestinal polypeptide stimulates astrocytes to secrete the thrombin-inhibiting neurotrophic serpin, protease nexin I.

P. Nelson, D. Brenneman, B. Festoff, 1996, Journal of neurobiology.

Interleukin-1 alpha and vasoactive interstinal peptide: Enigmatic regulation of neuronal survival

G. Glazner, I. Gozes, D. Brenneman, 1995, International Journal of Developmental Neuroscience.

Induction of Cholinergic Expression in Developing Spinal Cord Cultures

D. Brenneman, D. Warren, 1983, Journal of neurochemistry.

Vasoactive intestinal peptide: A neurotrophic releasing agent and an astroglial mitogen

D. Brenneman, T. Nicol, D. Warren, 1990, Journal of neuroscience research.

Identity of Neurotrophic Molecules Released from Astroglia by Vasoactive Intestinal Peptide a

I. Gozes, T. Phillips, D. Brenneman, 1997, Annals of the New York Academy of Sciences.

Ontogeny of enkephalin- and VIP-containing neurons in dissociated cultures of embryonic mouse spinal cord and dorsal root ganglia.

P. Giraud, R. Siegel, L. Eiden, 1988, Brain research. Developmental brain research.

Peptide t sequences prevent neuronal cell death produced by the envelope protein (gp 120) of the human immunodeficiency virus

C. Pert, D. Brenneman, M. Ruff, 1988 .

Vasoactive intestinal peptide regulation of nerve growth factor in the embryonic mouse

D. Brenneman, Joannam . Hill, S. McCune, 2002, Peptides.

The identification of secreted heat shock 60 -like protein from rat glial cells and a human neuroblastoma cell line

I. Gozes, R. Zamostiano, D. Brenneman, 1998, Neuroscience Letters.

Identification of VIP/PACAP receptors on rat astrocytes using antisense oligodeoxynucleotides

O. Ashur-Fabian, I. Gozes, D. Brenneman, 1997, Journal of Molecular Neuroscience.

Complex array of cytokines released by vasoactive intestinal peptide

I. Gozes, C. Spong, T. Phillips, 2003, Neuropeptides.

Chemokine release is associated with the protective action of PACAP-38 against HIV envelope protein neurotoxicity

C. Spong, T. Phillips, D. Brenneman, 2002, Neuropeptides.

Chemokines Released from Astroglia by Vasoactive Intestinal Peptide: Mechanism of Neuroprotection from HIV Envelope Protein Toxicity

C. Spong, T. Phillips, D. Brenneman, 2000, Annals of the New York Academy of Sciences.

Vasoactive Intestinal Peptide Releases Interleukin‐1 from Astrocytes

I. Gozes, T. Phillips, D. Brenneman, 1996, Annals of the New York Academy of Sciences.

Optimization of cytokine stability in stored amniotic fluid.

C. Spong, A. Ghidini, D. Brenneman, 2001, American journal of obstetrics and gynecology.

NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis.

O. Ashur-Fabian, I. Gozes, J. Busciglio, 2007, Current pharmaceutical design.

Behavioural and pharmacological effects of cannabidiol (CBD) and the cannabidiol analogue KLS‐13019 in mouse models of pain and reinforcement

D. Brenneman, W. Kinney, S. Ward, 2021, British journal of pharmacology.

Inhibition of human neuroblastoma growth by a specific VIP antagonist

I. Gozes, G. Lilling, D. Brenneman, 2007, Journal of Molecular Neuroscience.

Utilization of ascites plasma very low density lipoprotein triglycerides by Ehrlich cells.

A. A. Spector, D. Brenneman, A. Spector, 1974, Journal of lipid research.

A Novel VIP Responsive Gene: Activity Dependent Neuroprotective Protein

I. Gozes, A. Pinhasov, R. Zamostiano, 2000, Annals of the New York Academy of Sciences.

Knockdown siRNA Targeting the Mitochondrial Sodium-Calcium Exchanger-1 Inhibits the Protective Effects of Two Cannabinoids Against Acute Paclitaxel Toxicity

D. Brenneman, W. Kinney, S. Ward, 2019, Journal of Molecular Neuroscience.

VIP and peptides related to activity-dependent neurotrophic factor protect PC12 cells against oxidative stress

B. Solomon, I. Gozes, D. Brenneman, 2000, Journal of Molecular Neuroscience.

A femtomolar-acting neuroprotective peptide induces increased levels of heat shock protein 60 in rat cortical neurons: a potential neuroprotective mechanism

I. Gozes, A. Pinhasov, R. Zamostiano, 1999, Neuroscience Letters.

α1‐Adrenergic Receptor Mediates Arachidonic Acid Release in Spinal Cord Neurons Independent of Inositol Phospholipid Turnover

J. Axelrod, C. Felder, A. L. Ma, 1990, Journal of neurochemistry.

Effect of free fatty acid structure on binding to rat liver mitochondria.

A. A. Spector, D. Brenneman, A. Spector, 1972, Biochimica et biophysica acta.

Vasoactive Intestinal Peptide: Link between Electrical Activity and Glia‐mediated Neurotrophism

I. Gozes, T. Phillips, D. Brenneman, 1999, Annals of the New York Academy of Sciences.

Pharmacologically distinct vasoactive intestinal peptide binding sites: CNS localization and role in embryonic growth

I. Gozes, D. Brenneman, M. Fridkin, 1999, Neuroscience.

Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase Activating Peptide Receptors

D. Brenneman, I. Goze, J. Hill, 2009 .

Interaction between trophic action and electrical activity in spinal cord cultures.

P. Nelson, D. Brenneman, S. Fitzgerald, 1984, Brain research.

From vasoactive intestinal peptide (VIP) through activity-dependent neuroprotective protein (ADNP) to NAP

Inbar Pilzer, I. Gozes, A. D. Spier, 2007, Journal of Molecular Neuroscience.

A decomposition product of a contaminant implicated in L-tryptophan eosinophilia myalgia syndrome affects spinal cord neuronal cell death and survival through stereospecific, maturation and partly interleukin-1-dependent mechanisms.

E. Sternberg, M. Schultzberg, D. Brenneman, 1993, The Journal of pharmacology and experimental therapeutics.

Maternal regulation of embryonic growth: the role of vasoactive intestinal peptide.

C. Spong, D. Brenneman, G. Gibney, 1999, Endocrinology.

Cerebrospinal fluid from cognitively impaired patient with acquired immunodeficiency syndrome shows gp120-like neuronal killing in vitro.

C. Pert, F. Siegal, D. Brenneman, 1989, The American journal of medicine.

The development of spontaneous electrical activity in spinal cord cultures

G. Westbrook, D. Brenneman, 1985, International Journal of Developmental Neuroscience.

Vasoactive Intestinal Peptide and Astrocyte Mitogenesis: In Vitro and in Vivo Studies

D. Brenneman, Joannam . Hill, 1993 .

A selective small molecule NOP (ORL-1 receptor) partial agonist for the treatment of anxiety.

G. Bignan, P. Connolly, S. Middleton, 2015, Bioorganic & medicinal chemistry letters.

Extra-hippocampal projections of CCK neurons of the hippocampus and subiculum

T. O'donohue, G. Handelmann, D. Brenneman, 1983, Peptides.

2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.

Junya Qu, Allen B Reitz, Brett A Tounge, 2007, Journal of medicinal chemistry.

Excitatory amino acid regulation of the enkephalin phenotype in mouse embryonic spinal cord cultures.

D. Brenneman, S. Fitzgerald, D. von Agoston, 1993, Brain research. Developmental brain research.

A vasoactive intestinal peptide receptor analog alters the expression of homeobox genes.

I. Gozes, A. Pinhasov, D. Brenneman, 2002, Life sciences.

Neuroprotective strategy for Alzheimer disease: intranasal administration of a fatty neuropeptide.

I. Gozes, A. Bardea, R. Zamostiano, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain.

P. Gressens, I. Gozes, P. Evrard, 1997, The Journal of clinical investigation.

The formation of abnormal bile and cholesterol gallstones from dietary cholesterol in the prairie dog.

D. Brenneman, E. Forker, W. Connor, 1972, The Journal of clinical investigation.

A VIP hybrid antagonist: From developmental neurobiology to clinical applications

I. Gozes, D. Brenneman, M. Fridkin, 1995, Cellular and Molecular Neurobiology.

An antagonist to vasoactive intestinal peptide affects cellular functions in the central nervous system.

T. Moody, I. Gozes, D. Brenneman, 1991, The Journal of pharmacology and experimental therapeutics.

Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Polypeptide Inhibit Tumor Necrosis Factor α Transcriptional Activation by Regulating Nuclear Factor-kB and cAMP Response Element-binding Protein/c-Jun*

E. Muñoz-Elías, I. Gozes, M. Delgado, 1998, The Journal of Biological Chemistry.

Antagonism of VIP-stimulated cyclic AMP formation in chick brain

J. Zawilska, I. Gozes, D. Brenneman, 2003, Journal of Molecular Neuroscience.

Activity-dependent neurotrophic factor-9 and NAP promote neurite outgrowth in rat hippocampal and cortical cultures

C. Plata-salamán, M. D'Andrea, I. Gozes, 2007, Journal of Molecular Neuroscience.

Learning and sexual deficiencies in transgenic mice carrying a chimeric vasoactive intestinal peptide gene

I. Gozes, H. Westphal, D. Brenneman, 2007, Journal of Molecular Neuroscience.

P Agonists and 1 Tissue and ity : Effects on ration , Sexual Biologic Clock "

T. Moody, O. Ashur-Fabian, I. Gozes, 2006 .

Cloning and Characterization of the Human Activity-dependent Neuroprotective Protein*

E. Seroussi, J. Mulley, I. Gozes, 2001, The Journal of Biological Chemistry.

A Novel peptide prevents death in enriched neuronal cultures

I. Gozes, I. Zemlyak, D. Brenneman, 2000, Regulatory Peptides.

Activity-dependent neurotrophic factor: intranasal administration of femtomolar-acting peptides improve performance in a water maze.

I. Gozes, A. Bardea, A. Pinhasov, 2000, The Journal of pharmacology and experimental therapeutics.

A Novel Signaling Molecule for Neuropeptide Action: Activity‐dependent Neuroprotective Protein

G. Glazner, I. Gozes, A. Pinhasov, 1999, Annals of the New York Academy of Sciences.

VIP and d-ala-peptide T-amide release chemokines which prevent HIV-1 GP120-induced neuronal death

C. Pert, C. Spong, T. Phillips, 1999, Brain Research.

Complete Sequence of a Novel Protein Containing a Femtomolar‐Activity‐Dependent Neuroprotective Peptide

H. Bassan, G. Glazner, I. Gozes, 1999, Journal of neurochemistry.

Neurobehavioral Development of Neonatal Mice Following Blockade of VIP During the Early Embryonic Period

P. Gressens, I. Gozes, D. Brenneman, 1997, Peptides.

Growth Factor Properties of VIP during Early Brain Development

P. Gressens, P. Evrard, D. Brenneman, 1997, Annals of the New York Academy of Sciences.

Development of VIP Agonists and Antagonists with Tissue and Receptor Specificity: Effects on Behavioral Maturation, Sexual Function, and the Biologic Clock a

T. Moody, O. Ashur-Fabian, I. Gozes, 1996, Annals of the New York Academy of Sciences.

Subnanomolar concentration of VIP induces the nuclear translocation of protein kinase C in neonatal rat cortical astrocytes

D. Agoston, W. Anderson, D. Brenneman, 1994, Journal of neuroscience research.

Blockade of VIP during Neonatal Development Induces Neuronal Damage and Increases VIP and VIP Receptors in Brain

I. Gozes, D. Brenneman, R. Mervis, 1994, Annals of the New York Academy of Sciences.

HIV envelope protein-induced neuronal damage and retardation of behavioral development in rat neonates

D. Brenneman, R. Mervis, T. Moody, 1993, Brain Research.

Learning impairment following intracerebral administration of the HIV envelope protein gp120 or a VIP antagonist

L. Panlilio, I. Gozes, D. Brenneman, 1992, Brain Research.

A VIP antagonist distinguishes VIP receptors on spinal cord cells and lymphocytes

I. Gozes, D. Brenneman, M. Fridkin, 1991, Brain Research.

Vasoactive intestinal peptide potentiates sexual behavior: Inhibition by novel antagonist

I. Gozes, D. Brenneman, M. Fridkin, 1989, Regulatory Peptides.

Vasoactive intestinal peptide and electrical activity influence neuronal survival.

L. Eiden, D. Brenneman, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Peptide Modulation of Neuronal Differentiation in Culture

P. Nelson, D. Brenneman, 1987 .

Neurotrophic action of VIP on spinal cord cultures

R. Siegel, L. Eiden, D. Brenneman, 1985, Peptides.

Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide

Karen L. Elkins, Douglas E. Brenneman, David L. Ennist, 1988, Nature.

Cholesterol metabolism in the Ehrlich ascites tumor.

A. A. Spector, D. Brenneman, R. Mcgee, 1974, Cancer research.

Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).

K. Wilcox, H. White, D. Brenneman, 2013, Journal of medicinal chemistry.

I. Gozes, D. Brenneman, M. Fridkin, 2000, Journal of Molecular Neuroscience.

VIP: Molecular biology and neurobiological function

I. Gozes, D. Brenneman, 2007, Molecular Neurobiology.

Protective Peptides That Are Orally Active and Mechanistically Nonchiral

I. Gozes, C. Spong, A. Pinhasov, 2004, Journal of Pharmacology and Experimental Therapeutics.

A peptide derived from activity-dependent neuroprotective protein (ADNP) ameliorates injury response in closed head injury in mice.

Y. Cohen, Y. Assaf, O. Eizenberg, 2001, The Journal of pharmacology and experimental therapeutics.

CREB contributes to the increased neurite outgrowth of sensory neurons induced by vasoactive intestinal polypeptide and activity-dependent neurotrophic factor

I. Gozes, D. Brenneman, Suellen M. Walker, 2000, Brain Research.

Vasoactive intestinal peptide stimulation of human trabecular meshwork cell growth.

E. Higginbotham, B. Yue, D. Brenneman, 1997, Investigative ophthalmology & visual science.

A rapid method to quantify neurons in mixed cultures based on the specific binding of [3H]ouabain to neuronal Na+,K+-ATPase

S. Paul, D. Brenneman, M. Markwell, 1991, Brain Research.

High-Throughput siRNA-Based Functional Target Validation

Sergey E Ilyin, Claudia K Derian, Hong Xin, 2004, Journal of biomolecular screening.

Emerging paradigms in applied bioinformatics

Douglas E. Brenneman, Jack A. Kauffman, Frank A. Amato, 2003 .

Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads.

M. Vandermeeren, M. Mercken, C. Ho, 2010, Bioorganic & medicinal chemistry letters.

Peptide Intervention in Neuronal Death Caused by the HIV External Envelope Protein: Clinical Implications

D. Brenneman, 1990 .

Acquired immune deficiency syndrome and the developing nervous system.

I. Gozes, D. Brenneman, S. McCune, 1990, International review of neurobiology.

Effect of dietary lipid on locomotor activity and response to psychomotor stimulants

D. Brenneman, C. Rutledge, 2004, Psychopharmacology.

Cytokine Regulation of Neuronal Survival

T. Bártfai, I. Gozes, M. Schultzberg, 1992, Journal of neurochemistry.

Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome.

I. Gozes, C. Spong, D. Brenneman, 2001, The Journal of pharmacology and experimental therapeutics.

PACAP Functions as a Neurotrophic Factor a

I. Tatsuno, A. Arimura, D. Brenneman, 1994, Annals of the New York Academy of Sciences.

Anti-Inflammatory Properties of KLS-13019: a Novel GPR55 Antagonist for Dorsal Root Ganglion and Hippocampal Cultures

M. McDonnell, D. Brenneman, M. Abood, 2022, Journal of Molecular Neuroscience.

Neonatal mice of the down syndrome model, Ts65Dn, exhibit upregulated VIP measures and reduced responsiveness of cortical astrocytes to VIP stimulation

D. Brenneman, Joannam . Hill, N. Sahir, 2007, Journal of Molecular Neuroscience.

The neuroprotective peptide NAP inhibits the aggregation of the beta-amyloid peptide

O. Ashur-Fabian, I. Gozes, D. Brenneman, 2003, Peptides.

Activity-dependent neurotrophic factor (ADNF). An extracellular neuroprotective chaperonin?

I. Gozes, D. Brenneman, 1996, Journal of molecular neuroscience : MN.

Learning enhancement with neuropeptides.

C. Spong, D. Brenneman, L. Toso, 2006, American journal of obstetrics and gynecology.

A single administration of the peptide NAP induces long-term protective changes against the consequences of head injury

I. Gozes, E. Shohami, D. Brenneman, 2002, Journal of Molecular Neuroscience.

The expression of activity-dependent neuroprotective protein (ADNP) is regulated by brain damage and treatment of mice with the ADNP derived peptide, NAP, reduces the severity of traumatic head injury.

I. Gozes, E. Shohami, D. Brenneman, 2005, Current Alzheimer research.

Sexual dimorphism of activity-dependent neuroprotective protein in the mouse arcuate nucleus

I. Gozes, D. Brenneman, Joannam . Hill, 2004, Neuroscience Letters.

The role of activity-dependent neuroprotective protein in a mouse model of fetal alcohol syndrome.

C. Spong, D. Brenneman, S. Poggi, 2003, American journal of obstetrics and gynecology.

Differential expression of embryonic and maternal activity-dependent neuroprotective protein during mouse development.

I. Gozes, C. Spong, A. Pinhasov, 2002, American journal of obstetrics and gynecology.

NAP accelerates the performance of normal rats in the water maze

I. Gozes, A. Pinhasov, D. Brenneman, 2002, Journal of Molecular Neuroscience.

Vasoactive intestinal peptide and related molecules induce nitrite accumulation in the extracellular milieu of rat cerebral cortical cultures

O. Ashur-Fabian, I. Gozes, D. Brenneman, 2001, Neuroscience Letters.

Nonneuronal cells mediate neurotrophic action of vasoactive intestinal peptide

G. Westbrook, G. Foster, D. Brenneman, 1987, The Journal of cell biology.

Vasoactive intestinal peptide mRNA and immunoreactivity are decreased in fetal alcohol syndrome model

C. Spong, D. Brenneman, Joannam . Hill, 2002, Regulatory Peptides.

597 Oral prenatal treatment with peptides increases adult performance in a learning paradigm

C. Spong, D. Brenneman, I. Gozes, 2001 .

Novel peptides prevent alcohol-induced spatial learning deficits and proinflammatory cytokine release in a mouse model of fetal alcohol syndrome.

C. Spong, D. Brenneman, D. Abebe, 2005, American journal of obstetrics and gynecology.

Discovery of KLS-13019, a Cannabidiol-Derived Neuroprotective Agent, with Improved Potency, Safety, and Permeability.

Tao Qian, M. McDonnell, D. Brenneman, 2016, ACS medicinal chemistry letters.

A vasoactive intestinal peptide antagonist inhibits non-small cell lung cancer growth.

T. Moody, I. Gozes, D. Brenneman, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Vasoactive intestinal peptide antagonist retards the development of neonatal behaviors in the rat

I. Gozes, D. Brenneman, M. Fridkin, 1991, Peptides.

Morphological and biochemical differences expressed in separate dissociated cell cultures of dorsal and ventral halves of the mouse spinal cord

P. Guthrie, D. Brenneman, E. Neale, 1987, Brain Research.

Role of electrical activity and trophic factors during cholinergic development in dissociated cultures.

D. Brenneman, 1986, Canadian journal of physiology and pharmacology.

Neuronal Development in Culture

P. Nelson, D. Brenneman, 1985 .

Developmental and neurochemical specificity of neuronal deficits produced by electrical impulse blockade in dissociated spinal cord cultures.

P. Nelson, D. Brenneman, W. Habig, 1983, Brain research.

Superactive lipophilic peptides discriminate multiple vasoactive intestinal peptide receptors.

I. Gozes, G. Lilling, I. Ashkenazi, 1995, The Journal of pharmacology and experimental therapeutics.

Vasoactive intestinal peptide increases intracellular calcium in astroglia: synergism with alpha-adrenergic receptors.

A. Fatatis, J. Russell, D. Brenneman, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Potent gp120-like neurotoxic activity in the cerebrospinal fluid of HIV-infected individuals is blocked by peptide T

C. Pert, A. Salazar, D. Brenneman, 1992, Brain Research.

Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.

L. Leclercq, R. Iannucci, H. White, 2009, Journal of medicinal chemistry.

Small-Molecule Anticonvulsant Agents with Potent In Vitro Neuroprotection and Favorable Drug-Like Properties

D. Brenneman, A. Reitz, Garry R. Smith, 2014, Journal of Molecular Neuroscience.

Small Molecule Anticonvulsant Agents with Potent In Vitro Neuroprotection

Michael J. Zdilla, D. Brenneman, A. Reitz, 2012, Journal of molecular neuroscience : MN.

N-methyl-D-aspartate receptors influence neuronal survival in developing spinal cord cultures.

I. Forsythe, P. Nelson, D. Brenneman, 1990, Brain research. Developmental brain research.

Pharmacological Comparisons Between Cannabidiol and KLS-13019

D. Brenneman, W. Kinney, Dean Petkanas, 2018, Journal of Molecular Neuroscience.

Reduction of Submissive Behavior Model for antidepressant drug activity testing: study using a video-tracking system

D. Brenneman, E. Malatyńska, D. Rosenthal, 2005, Behavioural pharmacology.

Reduction of dominant or submissive behaviors as models for antimanic or antidepressant drug testing: Technical considerations

D. Brenneman, E. Malatyńska, J. Crooke, 2007, Journal of Neuroscience Methods.

Cholesteryl ester accumulation in Ehrlich cells induced by saturated fats.

D. Brenneman, R. Mcgee, A. Spector, 1975, Biochimica et biophysica acta.

Natural catalytic immunity is not restricted to autoantigenic substrates

D. Brenneman, S. Paul, G. Gololobov, 2000, Applied biochemistry and biotechnology.

Pharmacological Effects on Ceroid Lipofuscin and Neuronal Structure in Cln3∆ex7/8 Mouse Brain Cultures

D. Brenneman, D. Pearce, A. Kovács, 2017, Journal of Molecular Neuroscience.

Multi-determinate regulation of neuronal survival: Neuropeptides, excitatory amino acids and bioelectric activity

P. Nelson, D. Brenneman, Y. Chang, 1990, International Journal of Developmental Neuroscience.

Structural specificity of peptides influencing neuronal survival during development

G. Foster, D. Brenneman, 1987, Peptides.

gp120 as an etiologic agent for NeuroAIDS: neurotoxicity and model systems.

D. Brenneman, R. Mervis, S. McCune, 1994, Advances in neuroimmunology.

Knockdown siRNA Targeting the Mitochondrial Sodium-Calcium Exchanger-1 Inhibits the Protective Effects of Two Cannabinoids Against Acute Paclitaxel Toxicity

D. Brenneman, W. Kinney, S. Ward, 2019, Journal of Molecular Neuroscience.

Cholinergic stimulation increases thrombin activity and gene expression in cultured mouse muscle.

P. Nelson, G. Glazner, D. Brenneman, 1997, Brain research. Developmental brain research.

Protective peptides derived from novel glial proteins.

I. Gozes, C. Spong, D. Brenneman, 2000, Biochemical Society Transactions.

Protection against developmental and learning impairments in apolipoprotein e-deficient mice by activity-dependent femtomolar-acting peptides

I. Gozes, A. Bardea, D. Brenneman, 1997, Neuroscience Letters.

Calcium‐dependent regulation of the enkephalin phenotype by neuronal activity during early ontogeny

D. Agoston, L. Eiden, D. Brenneman, 1991, Journal of neuroscience research.

[3H]-Nitrendipine binding in developing dissociated fetal mouse spinal cord neurons.

D. Brenneman, M. Litzinger, 1985, Biochemical and Biophysical Research Communications - BBRC.

NEUROTROPHIC ACTION OF VIP : FROM CNS ONTOGENY TO THERAPEUTIC STRATEGY

P. Gressens, I. Gozes, D. Brenneman, 1998 .

Developmental changes in the inducibility of fos-like immunoreactivity in primary embryonic spinal cord cultures.

D. Brenneman, S. Fitzgerald, D. von Agoston, 1995, Brain research. Developmental brain research.

Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons

G. Yohrling, Boyu Zhao, D. Brenneman, 2009, Epilepsy Research.

A lipophilic vasoactive intestinal peptide analog enhances the antiproliferative effect of chemotherapeutic agents on cancer cell lines

T. Moody, I. Gozes, D. Brenneman, 2001, Cancer.

Differential expression of c-fos in a mouse model of fetal alcohol syndrome.

C. Spong, D. Brenneman, S. Poggi, 2003, American journal of obstetrics and gynecology.

VIP Neurotrophism in the Central Nervous System: Multiple Effectors and Identification of a Femtomolar‐Acting Neuroprotective Peptide

G. Glazner, I. Gozes, D. Brenneman, 1998, Annals of the New York Academy of Sciences.

Involvement of Pituitary Adenylate Cyclase‐Activating Polypeptide II Vasoactive Intestinal Peptide 2 Receptor in Mouse Neocortical Astrocytogenesis

P. Gressens, I. Gozes, P. Robberecht, 1998, Journal of neurochemistry.

Electrical development in spinal cord cell culture

H. Lecar, P. Nelson, M. Jackson, 1982, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Neuropeptides: brain messengers of many faces

R. Mains, A. Kastin, I. Gozes, 2001, Trends in Neurosciences.

Vasoactive intestinal peptide inhibits cytokine production in T lymphocytes through cAMP-dependent and cAMP-independent mechanisms

I. Gozes, D. Ganea, D. Brenneman, 1999, Regulatory Peptides.

Electrical activity of neurons and development of the brain

P. Nelson, D. Brenneman, 1982, Trends in Neurosciences.

Neuronal survival during electrical blockade is increased by 8-bromo cyclic adenosine 3',5' monophosphate.

D. Brenneman, S. Fitzgerald, M. Litzinger, 1985, The Journal of pharmacology and experimental therapeutics.

First, second, and third messenger control of VIP/PHI gene activity in neuroendocrine cells

D. Agoston, J. Waschek, R. Eskay, 1989, Regulatory Peptides.

Maternal regulation of embryonic growth: the role of vasoactive intestinal peptide.

C. Spong, D. Brenneman, G. Gibney, 1999, Endocrinology.

gp120 and neurotoxicity in vivo.

L. Mucke, D. Brenneman, S. Lipton, 1995, Trends in pharmacological sciences.

Regulation of Postimplantation Mouse Embryonic Growth by Maternal Vasoactive Intestinal Peptide

C. Spong, D. Brenneman, Susan J. Lee, 1999, Annals of the New York Academy of Sciences.

Vasoactive Intestinal Peptide: From Molecular Genetics to Neurotropism

I. Gozes, D. Brenneman, 1993 .

Multi-determinate regulation of neuronal survival: Neuropeptides, excitatory amino acids and bioelectric activity

P. Nelson, D. Brenneman, Y. Chang, 1990, International Journal of Developmental Neuroscience.

Activity-dependent neurotrophic factor: structure-activity relationships of femtomolar-acting peptides.

I. Gozes, D. Brenneman, M. Fridkin, 1998, The Journal of pharmacology and experimental therapeutics.

Neuropeptides and Neuronal Survival: Neuroprotective Strategy for Alzheimer's Disease a

I. Gozes, A. Bardea, R. Zamostiano, 1997, Annals of the New York Academy of Sciences.

Enkephalin Expression in Spinal Cord Neurons is Modulated by Drugs Related to Classical and Peptidergic Transmitters

G. Foster, L. Eiden, D. Brenneman, 1991, The European journal of neuroscience.

E. Muñoz-Elías, I. Gozes, M. Delgado, 1998, The Journal of Biological Chemistry.

Regulation of discrete sub-populations of transmitter-identified neurones after inhibition of electrical activity in cultures of mouse spinal cord

G. Foster, L. Eiden, D. Brenneman, 1989, Cell and Tissue Research.

Cytokines and the Brain 2. A Satellite Symposium to the Society for Neuroscience (30th) Annual Meeting Held in New Orleans, Louisiana on November 2-4, 2000

Steven F. Maier, Douglas E. Brenneman, Clark M. Blatteis, 2000 .

Growth of the Early Postimplantation Embryo

P. Gressens, D. Brenneman, Joannam . Hill, 1997, Annals of the New York Academy of Sciences.