Yuxing Li

发表

Receptor-mediated glutamate release from volume sensitive channels in astrocytes.

T. Takano, M. Nedergaard, G. Dienel, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Trazodone inhibits T-type calcium channels

J. Renger, Yuxing Li, R. Kraus, 2007, Neuropharmacology.

Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain.

D. Henze, S. Grauer, A. Palani, 2021, Journal of medicinal chemistry.

Discovery of a Potent, CNS‐Penetrant Orexin Receptor Antagonist Based on an N,N‐Disubstituted‐1,4‐diazepane Scaffold that Promotes Sleep in Rats

John D. Schreier, S. Doran, J. Renger, 2009, ChemMedChem.

Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve

D. Henze, C. Regan, Yuxing Li, 2022, Channels.

Discovery and expanded SAR of 4,4-disubstituted quinazolin-2-ones as potent T-type calcium channel antagonists.

Steven V. Fox, James C Barrow, Cuyue Tang, 2010, Bioorganic & medicinal chemistry letters.

Discovery of 4,4-Disubstituted Quinazolin-2-ones as T-Type Calcium Channel Antagonists.

Steven V. Fox, S. Doran, G. McGaughey, 2010, ACS medicinal chemistry letters.

In Vitro Characterization of T-Type Calcium Channel Antagonist TTA-A2 and In Vivo Effects on Arousal in Mice

Steven V. Fox, S. Doran, J. Renger, 2010, Journal of Pharmacology and Experimental Therapeutics.

Application of Pharmacokinetic-Pharmacodynamic Modeling to Inform Translation of In Vitro NaV1.7 Inhibition to In Vivo Pharmacological Response in Non-human Primate

D. Henze, C. Gibson, Yuxing Li, 2020, Pharmaceutical Research.

Antagonism of T-type calcium channels inhibits high-fat diet-induced weight gain in mice.

S. Doran, J. Renger, J. Barrow, 2009, The Journal of clinical investigation.

Pyridyl amides as potent inhibitors of T-type calcium channels.

Steven V. Fox, S. Doran, G. McGaughey, 2011, Bioorganic & medicinal chemistry letters.

Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice.

Edward C Sherer, John Majercak, Deping Wang, 2017, Bioorganic & medicinal chemistry letters.

Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodents.

Steven V. Fox, S. Doran, W. Zeng, 2010, ACS medicinal chemistry letters.

Nav1.7 target modulation and efficacy can be measured in nonhuman primate assays

D. Henze, Yuxing Li, R. Kraus, 2021, Science Translational Medicine.

Positive Allosteric Interaction of Structurally Diverse T-Type Calcium Channel Antagonists

Steven V. Fox, S. Doran, J. Renger, 2009, Cell Biochemistry and Biophysics.

Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model.

Michael A Rossi, D. Henze, J. Majercak, 2017, Bioorganic & medicinal chemistry letters.