T. Iba

T. Iba, K. Nagakari, M. Emmi, 2017, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

ISTH interim guidance on recognition and management of coagulopathy in COVID‐19

A. Falanga, J. Thachil, M. Levi, 2020, Journal of Thrombosis and Haemostasis.

TCRM_A_201954 791..802

H. Kamiyama, T. Iba, K. Niwa, 2019 .

Current status of venous thromboembolism development during the perioperative period for colorectal cancer, its prevention with enoxaparin, and monitoring methods

H. Kamiyama, T. Iba, K. Niwa, 2019, Therapeutics and clinical risk management.

Thrombin-Antithrombin System

T. Iba, 2020, Trauma Induced Coagulopathy.

Efficacy of antithrombin in preclinical and clinical applications for sepsis-associated disseminated intravascular coagulation

D. Saitoh, T. Iba, 2014, Journal of Intensive Care.

Newly Developed Recombinant Antithrombin Protects the Endothelial Glycocalyx in an Endotoxin-Induced Rat Model of Sepsis

I. Nagaoka, T. Iba, J. Levy, 2020, International journal of molecular sciences.

Protective effect of a newly developed fucose-deficient recombinant antithrombin against histone-induced endothelial damage

I. Nagaoka, T. Iba, Tatsuhiko Hirota, 2018, International Journal of Hematology.

Danaparoid sodium attenuates the increase in inflammatory cytokines and preserves organ function in endotoxemic rats

T. Miyasho, T. Iba, 2008, Critical care.

Platelet Activation and Thrombosis in COVID-19

T. Iba, J. Levy, Hideo Wada, 2022, Seminars in Thrombosis and Hemostasis.

Recent advances in the research and management of sepsis-associated DIC

I. Nagaoka, J. Connors, T. Iba, 2021, International Journal of Hematology.

Laboratory haemostasis monitoring in COVID‐19

A. Falanga, J. Thachil, M. Levi, 2020, Journal of Thrombosis and Haemostasis.

COVID-19 coagulopathy: is it disseminated intravascular coagulation?

M. Levi, T. Iba, 2020, Internal and Emergency Medicine.

Type and dose of heparin in Covid‐19: Reply

A. Falanga, J. Thachil, M. Levi, 2020, Journal of Thrombosis and Haemostasis.

Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID‐19

J. Douketis, W. Ageno, C. Samama, 2020, Journal of Thrombosis and Haemostasis.

Coagulation abnormalities and thrombosis in patients with COVID-19

J. Thachil, M. Levi, T. Iba, 2020, The Lancet Haematology.

Is postoperative polymyxin B hemoperfusion for abdominal septic shock really ineffective?

T. Iba, N. Hashiguchi, 2014, Critical care medicine.

Human Host Defense Cathelicidin Peptide LL-37 Enhances the Lipopolysaccharide Uptake by Liver Sinusoidal Endothelial Cells without Cell Activation

I. Nagaoka, Kaori Suzuki, H. Tamura, 2016, The Journal of Immunology.

Antithrombin

T. Iba, E. Nakarai, 1976, The Lancet.

Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils

I. Nagaoka, Yumi Kumagai, T. Iba, 2020, Innate immunity.

Alterations in circulating levels of soluble intercellular adhesion molecule-1 in sepsis.

T. Iba, A. Kidokoro, M. Fukunaga, 1997 .

Role of extracellular vesicles in the development of sepsis-induced coagulopathy

H. Ogura, T. Iba, 2018, Journal of Intensive Care.

ISTH guidelines for antithrombotic treatment in COVID‐19

C. Samama, A. Falanga, J. Thachil, 2022, Journal of Thrombosis and Haemostasis.

The roles of platelets in COVID-19-associated coagulopathy and vaccine-induced immune thrombotic thrombocytopenia

T. Iba, J. Levy, 2021, Trends in Cardiovascular Medicine.

Derangement of the endothelial glycocalyx in sepsis

T. Iba, J. Levy, 2019, Journal of thrombosis and haemostasis : JTH.

The Management of Post-surgical Acute Lung Injury—A Summary of Pharmacologic Treatment—

T. Iba, A. Mizushima, Y. Kamiyama, 2007 .

Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Takashi Ito, J. Thachil, T. Iba, 2019, Critical Care.

The authors reply

J. Thachil, M. Levi, J. Connors, 2020, Critical care medicine.

Factor Xa inhibitor attenuates leukocyte adhesion and thrombus formation in an experimental mouse model of the metabolic syndrome.

Y. Yanagawa, T. Iba, A. Ohsaka, 2013, Cardiovascular therapeutics.

Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction

I. Nagaoka, Y. Tabe, T. Iba, 2015, Intensive Care Medicine Experimental.

Antimicrobial cathelicidin peptide LL‑37 induces NET formation and suppresses the inflammatory response in a mouse septic model.

Y. Tabe, H. Tamura, H. Hosoda, 2017, Molecular medicine reports.

Nevertheless, the importance of coagulation abnormalities should be emphasized in international sepsis guidelines

O. Nishida, M. Levi, T. Iba, 2022, Journal of Intensive Care.

Hypofibrinogenemia is Associated With a High Degree of Risk in Infectious and Hematological Diseases: A Post-Hoc Analysis of Post-Marketing Surveillance of Patients With Disseminated Intravascular Coagulation Treated With Thrombomodulin Alfa

S. Madoiwa, T. Ikezoe, T. Iba, 2020 .

RE: The prothrombin time ratio is not a more effective marker for evaluating sepsis‐induced coagulopathy than fibrin‐related markers: Response to the Letter‐to‐the‐Editor by Dr Wada

T. van der Poll, J. Thachil, M. Levi, 2020, Journal of thrombosis and haemostasis : JTH.

Sepsis-induced Coagulopathy and Disseminated Intravascular Coagulation

T. Iba, J. Levy, 2020, Anesthesiology.

Recombinant human soluble thrombomodulin in patients with sepsis-associated coagulopathy (SCARLET): an updated meta-analysis

K. Yamakawa, T. Iba, J. Levy, 2019, Critical Care.

Formation of the venous thrombus after venous occlusion in the experimental mouse model of metabolic syndrome.

Y. Yanagawa, T. Iba, K. Niwa, 2012, Thrombosis research.

Recombinant thrombomodulin improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat LPS model.

Y. Yanagawa, T. Iba, M. Takemoto, 2013, Thrombosis research.

Rivaroxaban attenuates leukocyte adhesion in the microvasculature and thrombus formation in an experimental mouse model of type 2 diabetes mellitus.

Y. Tabe, T. Iba, A. Ohsaka, 2014, Thrombosis research.

Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation

M. Levi, T. Iba, J. Levy, 2019, Seminars in Thrombosis and Hemostasis.

PRETREATMENT OF SIVELESTAT SODIUM HYDRATE IMPROVES THE LUNG MICROCIRCULATION AND ALVEOLAR DAMAGE IN LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INFLAMMATION IN HAMSTERS

T. Iba, A. Kidokoro, K. Takuhiro, 2006, Shock.

COVID‐19: Thrombosis, thromboinflammation, and anticoagulation considerations

K. Ghadimi, J. Connors, T. Iba, 2021, International journal of laboratory hematology.

Vascular injury in acute infections and COVID-19: everything old is new again

J. Connors, T. Iba, J. Levy, 2020, Trends in Cardiovascular Medicine.

SSCG 2012 preview

Y. Yanagawa, T. Iba, 2012 .

Endothelial Injury in COVID-19 and Acute Infections: Putting the Pieces of the Puzzle Together.

T. Iba, J. Levy, E. Gardiner, 2021, Arteriosclerosis, thrombosis, and vascular biology.

DOACs and “newer” hemophilia therapies in COVID‐19: Reply

A. Falanga, J. Thachil, M. Levi, 2020, Journal of Thrombosis and Haemostasis.

Efficacy and Bleeding Risk of Antithrombin Supplementation in Patients With Septic Disseminated Intravascular Coagulation: A Third Survey

D. Saitoh, J. Kotani, S. Oda, 2017, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

The Comparison of the Protective Effects of α- and β-Antithrombin against Vascular Endothelial Cell Damage Induced by Histone in Vitro

I. Nagaoka, J. Thachil, T. Iba, 2017, TH Open.

Disseminated Intravascular Coagulation: The Past, Present, and Future Considerations.

J. Thachil, M. Levi, T. Iba, 2022, Seminars in thrombosis and hemostasis.

A new SOFA score calculation to improve the predictive performance for mortality in sepsis-associated disseminated intravascular coagulopathy patients.

T. Iba, J. Levy, M. Arakawa, 2020, Journal of critical care.

[Pretreatment with cilostazol protects against the vascular endothelial damage after ischemia/reperfusion].

T. Iba, 2008, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Usefulness of the APTT waveform for the diagnosis of DIC and prediction of the outcome or bleeding risk

T. Iba, M. Ikejiri, H. Wada, 2019, Thrombosis Journal.

Antimicrobial cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages and improves the survival of polybacterial septic mice.

I. Nagaoka, Kaori Suzuki, H. Tamura, 2016, International immunology.

The authors reply.

J. Thachil, M. Levi, J. Connors, 2020, Critical care medicine.

COVID-19-associated coagulopathy and thrombosis

M. Hiki, T. Iba, 2020 .

Is the neutrophil a ‘prima donna’ in the procoagulant process during sepsis?

I. Nagaoka, Y. Tabe, T. Iba, 2014, Critical Care.

Changes in Circulating Levels of Tissue Factor and Tissue Factor Pathway Inhibitor in SIRS, Septic MODS and Septic DIC

T. Iba, A. Kidokoro, K. Takuhiro, 1997 .

ENOXAPARIN ATTENUATES ENDOTHELIAL DAMAGE WITH LESS BLEEDING COMPARED WITH UNFRACTIONATED HEPARIN IN ENDOTOXEMIC RATS

T. Iba, T. Takayama, 2009, Shock.

Differences and similarities between disseminated intravascular coagulation and thrombotic microangiopathy

T. Iba, H. Wada, M. Matsumoto, 2018, Thrombosis Journal.

A re‐evaluation of the D‐dimer cut‐off value for making a diagnosis according to the ISTH overt‐DIC diagnostic criteria: communication from the SSC of the ISTH

J. Thachil, T. Iba, H. Wada, 2018, Journal of thrombosis and haemostasis : JTH.

Evaluation of Factor Xa-Specific Chromogenic Substrate Assays and the Determination of Pharmacokinetics of Fondaparinux

Y. Tabe, J. Aoki, R. Sadatsuki, 2016, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

A Proposal of the Modification of Japanese Society on Thrombosis and Hemostasis (JSTH) Disseminated Intravascular Coagulation (DIC) Diagnostic Criteria for Sepsis-Associated DIC

M. Di Nisio, J. Thachil, D. Saitoh, 2018, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

The influence of hyperglycemia on neutrophil extracellular trap formation and endothelial glycocalyx damage in a mouse model of type 2 diabetes.

T. Iba, J. Levy, Tatsuhiko Hirota, 2020, Microcirculation.

Physiological Levels of Pentraxin 3 and Albumin Attenuate Vascular Endothelial Cell Damage Induced by Histone H3 In Vitro

I. Nagaoka, J. Thachil, T. Hamakubo, 2016, Microcirculation.

Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model

T. Iba, A. Kidokoro, K. Nagakari, 2005, Critical care medicine.

A CASE REPORT OF SPINDLE CELL CARCINOMA IN BILATERAL SYNCHRONOUS BREAST CANCER

T. Iba, A. Kidokoro, H. Horiuchi, 1989 .

COMPARISON OF THE PROTECTIVE EFFECTS OF TYPE III PHOSPHODIESTERASE (PDE3) INHIBITOR (CILOSTAZOL) AND ACETYLSALICYLIC ACID ON INTESTINAL MICROCIRCULATION AFTER ISCHEMIA REPERFUSION INJURY IN MICE

T. Iba, A. Kidokoro, K. Takuhiro, 2006, Shock.

Effect of hemoperfusion using polymyxin B-immobilized fibers on non-shock rat sepsis model.

T. Miyasho, T. Iba, S. Kawasaki, 2011, Journal of Surgical Research.

The role of platelets in heat-related illness and heat-induced coagulopathy.

J. Helms, M. Levi, T. Iba, 2022, Thrombosis research.

Perioperative Anaphylaxis

T. Iba, J. Levy, C. Tacquard, 2022, Anesthesiology.

Antithrombin ameliorates endotoxin-induced organ dysfunction more efficiently when combined with danaparoid sodium than with unfractionated heparin

T. Iba, A. Kidokoro, K. Nagakari, 2005, Intensive Care Medicine.

Neutrophil extracellular traps induce IL-1β production by macrophages in combination with lipopolysaccharide.

I. Nagaoka, Y. Tabe, H. Tamura, 2017, International journal of molecular medicine.

Intracellular communication and immunothrombosis in sepsis

M. Levi, T. Iba, J. Levy, 2022, Journal of thrombosis and haemostasis : JTH.

Differential diagnoses for sepsis‐induced disseminated intravascular coagulation: communication from the SSC of the ISTH

J. Thachil, M. Levi, T. Iba, 2019, Journal of thrombosis and haemostasis : JTH.

The progression from coagulopathy to disseminated intravascular coagulation in representative underlying diseases.

J. Thachil, M. Levi, T. Iba, 2019, Thrombosis research.

Activated protein C suppresses the production of pro-inflammatory cytokines and the leukocyte-endothelial interaction in rat LPS model

T. Iba, A. Kidokoro, K. Nagakari, 2005 .

Therapeutic approach to the septic organ dysfunction by anti-coagulant therapy

T. Iba, Y. Ujike, 2008 .

Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis.

M. Hiki, I. Nagaoka, T. Iba, 2018, Thrombosis research.

High-Dose Antithrombin Therapy for Sepsis: Mechanisms of Action

T. Iba, A. Kidokoro, 2002, Shock.

Increased plasma levels of soluble thrombomodulin in patients with sepsis and organ failure

T. Iba, A. Kidokoro, T. Fukunaga, 1995, Surgery Today.

A multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: Comparing current criteria*

Yasuhiro Ohtomo, Satoshi Gando, Kohji Okamoto, 2006, Critical care medicine.

The anticoagulant therapy for sepsis-associated disseminated intravascular coagulation.

I. Nagaoka, T. Iba, Marcel Boulat, 2013, Thrombosis research.

ASSOCIATION BETWEEN THE SEVERITY OF SEPSIS AND THE CHANGES IN HEMOSTATIC MOLECULAR MARKERS AND VASCULAR ENDOTHELIAL DAMAGE MARKERS

T. Iba, A. Kidokoro, M. Fukunaga, 2005, Shock.

The usefulness of antithrombin activity monitoring during antithrombin supplementation in patients with sepsis-associated disseminated intravascular coagulation.

J. Thachil, D. Saitoh, T. Iba, 2015, Thrombosis research.

SIRS-ASSOCIATED COAGULOPATHY AND ORGAN DYSFUNCTION IN CRITICALLY ILL PATIENTS WITH THROMBOCYTOPENIA

S. Kushimoto, D. Saitoh, H. Ishikura, 2007, Shock.

Characteristics of Severe Alcoholic Ketoacidosis with a Reversible Visual Disturbance

Y. Yanagawa, T. Iba, Y. Hirano, 2012 .

Whole Body CT for a Patient with Sepsis

T. Naito, Y. Yanagawa, T. Iba, 2013 .

Selective hydrogenation of alkynes by hectorite-intercalated PD[II] complexes

T. Iba, S. Shimazu, T. Uematsu, 1989 .

New therapeutic options for patients with sepsis and disseminated intravascular coagulation.

I. Nagaoka, T. Iba, N. Hashiguchi, 2014, Polskie Archiwum Medycyny Wewnetrznej.

The Current Status of Sepsis Research in Japan in Comparison to the Status of International Research

T. Iba, S. Kawasaki, 2010 .

Therapeutic Approach for Severe Sepsis Based on the Evidence 2007

T. Iba, 2008 .

The Significance of Humoral Mediators in Gram-Positive Infection

T. Iba, A. Kidokoro, T. Fukunaga, 1993 .

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

M. Egi, S. Taito, N. Shime, 2021, Journal of Intensive Care.

Antimicrobial Cathelicidin Peptide LL-37 Inhibits the LPS/ATP-Induced Pyroptosis of Macrophages by Dual Mechanism

I. Nagaoka, Kaori Suzuki, H. Tamura, 2014, PloS one.

The efficacy of long-term oral chemotherapy with 5′-deoxy-5-fluorouridine and cyclophosphamide for recurrent breast cancer

T. Iba, A. Kidokoro, M. Fukunaga, 2004, International Journal of Clinical Oncology.

without Cell Activation Uptake by Liver Sinusoidal Endothelial Cells LL-37 Enhances the Lipopolysaccharide Human Host Defense Cathelicidin Peptide

Kaori Suzuki, T. Iba, Isao, 2016 .

Neutrophil cell death in response to infection and its relation to coagulation

Yoko Tabe, Toshiaki Iba, I. Nagaoka, 2013, Journal of Intensive Care.

Defining trauma‐induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH

E. Moore, M. Schreiber, R. Medcalf, 2020, Journal of thrombosis and haemostasis : JTH.

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)

A. Matsuda, M. Egi, N. Shime, 2018, Journal of Intensive Care.

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG 2016)

A. Matsuda, M. Egi, N. Shime, 2018, Acute medicine & surgery.

Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation

T. van der Poll, J. Thachil, M. Levi, 2019, Journal of thrombosis and haemostasis : JTH.

DIC in obstetrics: Diagnostic score, highlights in management, and international registry‐communication from the DIC and Women's Health SSCs of the International Society of Thrombosis and Haemostasis

J. Thachil, O. Erez, M. Othman, 2019, Journal of thrombosis and haemostasis : JTH.

Inflammation, coagulation, and cellular injury in heat-induced shock

J. Helms, M. Levi, T. Iba, 2023, Inflammation Research.

Proposal of the Definition for COVID-19-Associated Coagulopathy

J. Thachil, M. Levi, T. Iba, 2021, Journal of clinical medicine.

The unique characteristics of COVID-19 coagulopathy

Toshiaki Iba, J. Thachil, M. Levi, 2020, Critical Care.

Coagulopathy of Coronavirus Disease 2019

J. Thachil, M. Levi, J. Connors, 2020, Critical care medicine.

Tissue Plasminogen Activator Expression in Endothelial Cells Exposed to Cyclic Strain in Vitro

B. Sumpio, T. Iba, B E Sumpio, 1992, Cell transplantation.

Total parenteral nutrition supplemented with medium-chain triacylglycerols prevents atrophy of the intestinal mucosa in septic rats.

T. Iba, A. Kidokoro, Y. Kaneshiro, 1998, Nutrition.

Lessons from the recent sepsis trials

Y. Yanagawa, T. Iba, 2012 .

Physiological protease inhibitors

S. Kushimoto, T. Iba, 2006 .

Evaluation of surgical stress in laparoscopic-assisted colectomy for advanced colorectal cancer

T. Iba, A. Kidokoro, T. Fukunaga, 2005 .

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J‐SSCG 2020)

M. Egi, S. Taito, N. Shime, 2021, Acute medicine & surgery.

A case of paraparesis with thoracic ossification of the posterior longitudinal ligament and the ligamentum flavum induced by falling down on the abdomen

K. Kaneko, Y. Yanagawa, T. Iba, 2014, Acute medicine & surgery.

COVID‐19 coagulopathy in pregnancy: Critical review, preliminary recommendations, and ISTH registry—Communication from the ISTH SSC for Women’s Health

J. Thachil, O. Erez, M. Othman, 2020, Journal of Thrombosis and Haemostasis.

Antithrombin modulates the leukocyte-endothelial cell interaction in the staphylococcal enterotoxin B-challenged mouse.

T. Iba, A. Kidokoro, M. Fukunaga, 2003, The Journal of trauma.

Hypofibrinogenemia is associated with a high degree of risk in infectious diseases: a post-hoc analysis of post-marketing surveillance of patients with disseminated intravascular coagulation treated with thrombomodulin alfa

S. Madoiwa, T. Ikezoe, T. Iba, 2021, Thrombosis Journal.

Severe Antithrombin Deficiency May be Associated With a High Risk of Pathological Progression of DIC With Suppressed Fibrinolysis

S. Madoiwa, T. Ikezoe, T. Iba, 2020, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

ALTERATIONS IN COAGULATION AND FIBRINOLYSIS DURING SEPSIS

T. Iba, A. Kidokoro, M. Fukunaga, 1996, Shock.

Efficacy and bleeding risk of antithrombin supplementation in septic disseminated intravascular coagulation: a prospective multicenter survey.

T. Iba, H. Wada, Daizoh Saito, 2012, Thrombosis research.

Antithrombin III Effects on the Production of Vasoactive Substances in Endotoxemic Rats

T. Iba, A. Kidokoro, Y. Kaneshiro, 1999 .

The Effect of Antithrombin III on Cytokine Production in Endotoxemic Rats

T. Iba, A. Kidokoro, Y. Kaneshiro, 1999 .

Improvement in Sinusoidal Circulation with Supplement of Antithrombin III in Endotoxemic Rats

T. Iba, Nobuhiro Sato, F. Momose, 1998 .

The role of the endothelium in changes in procoagulant activity in sepsis.

T. Iba, A. Kidokoro, Y. Yagi, 1998, Journal of the American College of Surgeons.

Evaluation of haemostatic molecular markers for diagnosis of disseminated intravascular coagulation in patients with infections

T. Iba, S. Gando, H. Wada, 2006, Thrombosis and Haemostasis.

Revision of the Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC) diagnostic criteria using antithrombin activity

M. Di Nisio, J. Thachil, D. Saitoh, 2016, Critical Care.

Evaluation of a Rat Model for Disseminated Intravascular Coagulation Developed by Infusion of Lipopolysaccharide

T. Iba, A. Kidokoro, Y. Yagi, 1997 .

Combination of antithrombin and recombinant thrombomodulin attenuates leukocyte-endothelial interaction and suppresses the increase of intrinsic damage-associated molecular patterns in endotoxemic rats.

I. Nagaoka, T. Iba, N. Hashiguchi, 2014, The Journal of surgical research.

Enoxaparin and fondaparinux attenuates endothelial damage in endotoxemic rats

T. Iba, Toshihiro Tajirika, Koichiro Aihara, 2012, The journal of trauma and acute care surgery.

Factor Xa-Inhibitor (Dx-9065a) Modulates the Leukocyte-Endothelial Cell Interaction in Endotoxemic Rat

T. Iba, A. Kidokoro, S. Kunitada, 2002, Shock.

How to manage coagulopathies in critically ill patients

F. Meziani, J. Helms, M. Levi, 2023, Intensive Care Medicine.

Anticoagulant therapy for sepsis‐associated disseminated intravascular coagulation: the view from Japan

J. Thachil, T. Iba, S. Gando, 2014, Journal of thrombosis and haemostasis : JTH.

Harmonized guidance for disseminated intravascular coagulation from the International Society on Thrombosis and Haemostasis and the current status of anticoagulant therapy in Japan: a rebuttal.

T. Iba, 2013 .

Harmonized guidance for disseminated intravascular coagulation from the International Society on Thrombosis and Haemostasis and the current status of anticoagulant therapy in Japan

T. Iba, 2013, Journal of thrombosis and haemostasis : JTH.

Prevention of venous thromboembolism (VTE) in ICU: an overview of newly developed anticoagulants

T. Iba, H. Wada, 2012 .

Advance in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation

T. Iba, J. Levy, T. Warkentin, 2019, Journal of clinical medicine.

Coagulopathy in COVID‐19

J. Thachil, M. Levi, T. Iba, 2020, Journal of Thrombosis and Haemostasis.

Viral-Induced Inflammatory Coagulation Disorders: Preparing for Another Epidemic

M. Levi, T. Iba, J. Levy, 2021, Thrombosis and Haemostasis.

Sepsis-associated disseminated intravascular coagulation and its differential diagnoses

S. Kushimoto, Y. Umemura, T. Iba, 2019, Journal of Intensive Care.

Proposal of a two‐step process for the diagnosis of sepsis‐induced disseminated intravascular coagulation

J. Thachil, M. Levi, K. Yamakawa, 2019, Journal of thrombosis and haemostasis : JTH.

New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey

J. Thachil, T. Iba, J. Levy, 2017, BMJ Open.

Thrombosis and thrombocytopenia in COVID-19 and after COVID-19 vaccination

T. Iba, J. Levy, Jerrold H. Levy, 2022, Trends in Cardiovascular Medicine.

Clinical course and outcome of disseminated intravascular coagulation diagnosed by Japanese Association for Acute Medicine criteria

S. Kushimoto, D. Saitoh, H. Ishikura, 2008, Thrombosis and Haemostasis.

Thrombosis and COVID-19: Controversies and (Tentative) Conclusions.

J. Connors, R. Gandhi, T. Iba, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Evaluation of New Japanese Diagnostic Criteria for Disseminated Intravascular Coagulation in Critically Ill Patients

M. Nakagawa, A. Murata, T. Iba, 2005, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Elevated Plasma Soluble C-Type Lectin-like Receptor 2 Is Associated with the Worsening of Coronavirus Disease 2019

M. Shimaoka, K. Shiraki, T. Iba, 2022, Journal of clinical medicine.

Soluble C-Type Lectin-Like Receptor 2 Is a Biomarker for Disseminated Intravascular Coagulation

M. Shimaoka, K. Shiraki, T. Iba, 2021, Journal of clinical medicine.

Managing thrombosis and cardiovascular complications of COVID-19: answering the questions in COVID-19-associated coagulopathy

J. Thachil, M. Levi, J. Connors, 2021, Expert review of respiratory medicine.

Kinetics of Circulating Damage-Associated Molecular Patterns in Sepsis

T. Iba, T. Miki, 2015, Journal of immunology research.

Communication from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis on sepsis-induced coagulopathy in the management of sepsis.

J. Helms, J. Thachil, M. Levi, 2023, Journal of thrombosis and haemostasis : JTH.

Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?

J. Connors, T. Iba, H. Wada, 2021, International Journal of Hematology.

Glycocalyx regulates the intravascular hemostasis

T. Iba, 2016 .

Juntendo Medical Journal

T. Iba, 2014 .

Multiple biomarkers of sepsis identified by novel time-lapse proteomics of patient serum

Kei Ujimoto, Nobuhiro Hayashi, Takahiro Miki, 2019, PloS one.

Ischemic limb necrosis in septic shock: What is the role of high‐dose vasopressor therapy?

R. Hotchkiss, S. van Diepen, K. Ghadimi, 2019, Journal of thrombosis and haemostasis : JTH.

Sepsis-Associated DIC with Decreased Levels of Antithrombin and Fibrinogen is the Target for Combination Therapy with Thrombomodulin Alfa and Antithrombin

S. Madoiwa, T. Ikezoe, T. Iba, 2022, TH Open.

Efficacy and safety of recombinant human soluble thrombomodulin in patients with sepsis‐associated coagulopathy: A systematic review and meta‐analysis

J. Vincent, M. Di Nisio, E. Porreca, 2020, Journal of Thrombosis and Haemostasis.

Sepsis-Induced Coagulopathy and Japanese Association for Acute Medicine DIC in Coagulopathic Patients with Decreased Antithrombin and Treated by Antithrombin

T. Hifumi, K. Yamakawa, T. Iba, 2018, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Neutrophil extracellular traps induce IL-1β production by macrophages in combination with lipopolysaccharide

I. Nagaoka, Y. Tabe, H. Tamura, 2017, International journal of molecular medicine.

Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model

T. Iba, K. Nakajima, T. Takayama, 2009, Critical care.

THREE CASES OF HETEROTOPIC BONE FORMATION IN LAPAROTOMY SCARS

T. Iba, M. Fukunaga, Akio Kidokoroi, 1987 .

Imbalance between Coagulation and Fibrinolysis in Sepsis

T. Iba, A. Kidokoro, T. Fukunaga, 1995 .

Frequency and hemostatic abnormalities in pre-DIC patients.

S. Madoiwa, I. Maruyama, S. Kushimoto, 2010, Thrombosis research.

Changes in Plasma Levels of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Sepsis with Organ Failure

T. Iba, A. Kidokoro, T. Fukunaga, 1994 .

Natural history of disseminated intravascular coagulation diagnosed based on the newly established diagnostic criteria for critically ill patients: Results of a multicenter, prospective survey*

S. Kushimoto, D. Saitoh, H. Ishikura, 2008, Critical care medicine.

The obstacles that should be overcome to develop new anticoagulants for severe sepsis.

T. Iba, 2014, Critical care medicine.

Effects of combination therapy using antithrombin and thrombomodulin for sepsis-associated disseminated intravascular coagulation

D. Saitoh, A. Hagiwara, T. Iba, 2017, Annals of Intensive Care.

Efficacy and bleeding risk of antithrombin supplementation in septic disseminated intravascular coagulation: a secondary survey

D. Saitoh, T. Iba, H. Wada, 2014, Critical Care.

A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis

S. Kushimoto, Y. Inoue, D. Saitoh, 2013, Critical Care.

Underlying disorders of disseminated intravascular coagulation: Communication from the ISTH SSC Subcommittees on Disseminated Intravascular Coagulation and Perioperative and Critical Care Thrombosis and Hemostasis

M. Di Nisio, V. Vicente, O. Erez, 2020, Journal of thrombosis and haemostasis : JTH.

Diagnosis of sepsis‐induced disseminated intravascular coagulation and coagulopathy

S. Kushimoto, Y. Umemura, T. Iba, 2019, Acute medicine & surgery.

Protective Effects of Antithrombin III on Organ Dysfunction Induced by the Continuous Infusion of Endotoxin in Rats

T. Iba, A. Kidokoro, Y. Kaneshiro, 1998 .

Disseminated intravascular coagulation (DIC) diagnosed based on the Japanese Association for Acute Medicine criteria is a dependent continuum to overt DIC in patients with sepsis.

S. Kushimoto, D. Saitoh, H. Ishikura, 2009, Thrombosis research.

The Roles of Coagulation Disorder and Microthrombosis in Sepsis: Pathophysiology, Diagnosis, and Treatment.

Y. Umemura, T. Iba, H. Wada, 2021, Archives of medical research.

Combination of antithrombin and recombinant thrombomodulin modulates neutrophil cell-death and decreases circulating DAMPs levels in endotoxemic rats.

I. Nagaoka, Y. Tabe, T. Iba, 2014, Thrombosis research.

A Case of Lung Lesions Induced by a soccer Ball

Y. Yanagawa, T. Iba, Hiroshi Tanaka, 2013 .

Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia

T. Iba, J. Levy, T. Warkentin, 2021, Critical care medicine.

Morphological Changes in Blood Cells in a Rat Model of Heatstroke: A Pilot Study

T. Iba, J. Levy, K. Kondo, 2022, Journal of clinical medicine.

The absence of typical pneumonia symptoms in a patient with rheumatoid arthritis during tocilizumab and steroid treatment

Y. Yanagawa, H. Kato, T. Iba, 2012, BMJ Case Reports.

Effect of Hemoperfusion Using Polymyxin B-immobilized Fibers on Acute Lung Injury in a Rat Sepsis Model

I. Nagaoka, T. Iba, M. Nagayama, 2014, International journal of medical sciences.

Predicting the severity of systemic inflammatory response syndrome (SIRS)-associated coagulopathy with hemostatic molecular markers and vascular endothelial injury markers.

S. Kushimoto, D. Saitoh, A. Murata, 2007, The Journal of trauma.

Impact of Extended Duration of Polymyxin B-Immobilized Fiber Column Direct Hemoperfusion on Hemodynamics, Vasoactive Substance Requirement, and Pulmonary Oxygenation in Patients with Sepsis: An Observational Study

C. Ronco, T. Iba, C. Mitaka, 2020, Blood Purification.

THE EVALUATION OF BCA225 AS A NEW TUMORMARKER IN BREAST CARCINOMA

T. Iba, A. Kidokoro, K. Ishi, 1990 .

Addition of recommendations for the use of recombinant human thrombomodulin to the "Expert consensus for the treatment of disseminated intravascular coagulation in Japan".

S. Madoiwa, S. Kushimoto, T. Iba, 2014, Thrombosis research.

The comparison of British guidelines and Japanese guidelines for septic DIC

T. Iba, 2009 .

The current status of the therapeutic approach for severe sepsis in Japan and its comparison to the international guidelines

H. Ishikura, T. Iba, T. Mayumi, 2009 .

Polymyxin B-Immobilized Fiber Column Direct Hemoperfusion for Micro-Preemie Infants with Septic Shock. Is Extended Duration Better than Early Start? Comment to the Letter to the Editor of Nishizaki and Colleagues

C. Ronco, T. Iba, C. Mitaka, 2021, Blood Purification.

Thrombotic Mechanism Involving Platelet Activation, Hypercoagulability and Hypofibrinolysis in Coronavirus Disease 2019

M. Shimaoka, K. Shiraki, T. Iba, 2023, International journal of molecular sciences.

Does TeamSTEPPS affect psychological status?

T. Iba, Naruaki Imoto, Atsushi Yamada, 2019, International journal of health care quality assurance.

Comparison of prothrombin time tests used in the monitoring of edoxaban and their evaluation as indicators of the reversal effect

M. Hiki, Y. Tabe, T. Iba, 2016, International Journal of Hematology.

Perioperative Anaphylaxis: Reply.

T. Iba, J. Levy, C. Tacquard, 2023, Anesthesiology.

The role of neutrophil in activation of coagulation and thrombus formation

T. Iba, 2016 .

The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation

J. Helms, J. Connors, T. Iba, 2023, Journal of Intensive Care.

Communication from the SSC of the ISTH on vascular endothelium-related biomarkers in DIC

S. Susen, J. Thachil, M. Levi, 2022, Journal of Thrombosis and Haemostasis.

Newly Proposed Sepsis-Induced Coagulopathy Precedes International Society on Thrombosis and Haemostasis Overt-Disseminated Intravascular Coagulation and Predicts High Mortality

M. Di Nisio, J. Thachil, T. Iba, 2020, Journal of intensive care medicine.

Scholarly publishing cannot fit to a regular business model

T. Iba, 2013 .

The wind changed direction and the big river still flows: from EUPHRATES to TIGRIS

T. Iba, David J. Klein, 2019, Journal of Intensive Care.

[A case of gallbladder cancer with marked response to EAP treatment].

T. Iba, A. Kidokoro, T. Fukunaga, 1992, Gan to kagaku ryoho. Cancer & chemotherapy.

Antithrombin supplementation and risk of bleeding in patients with sepsis-associated disseminated intravascular coagulation.

M. Di Nisio, J. Thachil, D. Saitoh, 2016, Thrombosis research.

Diagnosis of sepsis‐induced disseminated intravascular coagulation and coagulopathy

S. Kushimoto, Y. Umemura, T. Iba, 2019, Acute medicine & surgery.

Oh, how hard it is to open the gate for sepsis trials: lessons from SCARLET

T. Iba, Hiroshi Tanaka, 2018, Acute medicine & surgery.

The effect of plasma-derived activated protein C on leukocyte cell-death and vascular endothelial damage.

T. Iba, K. Nagakari, 2015, Thrombosis Research.

The roles of platelets in COVID-19-associated coagulopathy and vaccine-induced immune thrombotic thrombocytopenia

T. Iba, J. Levy, Jerrold H. Levy, 2021, Trends in Cardiovascular Medicine.

Super Formula for Diagnosing Disseminated Intravascular Coagulation Using Soluble C-Type Lectin-like Receptor 2

M. Shimaoka, K. Shiraki, T. Iba, 2023, Diagnostics.

Usefulness of Measuring Changes in SOFA Score for the Prediction of 28-Day Mortality in Patients With Sepsis-Associated Disseminated Intravascular Coagulation

O. Nishida, T. Iba, H. Wada, 2019, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Prediction of Early Death in Patients With Sepsis-Associated Coagulation Disorder Treated With Antithrombin Supplementation

T. Iba, H. Wada, J. Levy, 2018, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

The meanings of DIC diagnostic criteria.

T. Iba, 2012, Thrombosis research.

criteria is to serve the platform to study DIC, and to perform the uni-

T. Iba, 2012 .

Is antithrombin III for sepsis-associated disseminated intravascular coagulation really ineffective?

J. Thachil, T. Iba, 2016, Intensive Care Medicine.

DOACs and ‘newer’ haemophilia therapies in COVID-19

A. Falanga, J. Thachil, N. Tang, 2020 .

What Role Does Microthrombosis Play in Long COVID?

T. Iba, Jerrold H. Levy, Jean M. Connors, 2023, Seminars in Thrombosis and Hemostasis.

A commentary on "Thromboinflammation in long COVID - the elusive key to post-infection sequelae?"

T. Iba, J. Levy, 2023, Journal of thrombosis and haemostasis : JTH.