E. Miller

发表

Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease.

E. Brilakis, J. Witztum, P. Berger, 2005, The New England journal of medicine.

Effect of the antioxidant N,N'-diphenyl 1,4-phenylenediamine (DPPD) on atherosclerosis in apoE-deficient mice.

D. Steinberg, R. Tangirala, E. Miller, 1995, Arteriosclerosis, thrombosis, and vascular biology.

High-Dose Atorvastatin Reduces Total Plasma Levels of Oxidized Phospholipids and Immune Complexes Present on Apolipoprotein B-100 in Patients With Acute Coronary Syndromes in the MIRACL Trial

W. Sasiela, J. Witztum, S. Tsimikas, 2004, Circulation.

Local Expression of Platelet-Activating Factor-Acetylhydrolase Reduces Accumulation of Oxidized Lipoproteins and Inhibits Inflammation, Shear Stress-Induced Thrombosis, and Neointima Formation in Balloon-Injured Carotid Arteries in Nonhyperlipidemic Rabbits

Y. Sasaguri, H. Ueno, J. Witztum, 2005, Circulation.

Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins.

E. Dennis, J. Berliner, N. Leitinger, 1999, The Journal of clinical investigation.

The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and beta2 glycoprotein 1 (and other proteins).

J. Witztum, D. Branch, E. Miller, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.

R. Terkeltaub, P. Reaven, J. Witztum, 1996, The Journal of clinical investigation.

Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.

J. Witztum, U. Steinbrecher, L. Curtiss, 1996, The Journal of clinical investigation.

Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis.

S. Young, R. Tangirala, E. Miller, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Immunological evidence for the presence of advanced glycosylation end products in atherosclerotic lesions of euglycemic rabbits.

T. Koschinsky, A. Cerami, H. Vlassara, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study.

Qingbo Xu, M. Mayr, S. Kiechl, 2006, Journal of the American College of Cardiology.

Low density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis.

D. Steinberg, J. Witztum, S. Parthasarathy, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Enhanced Macrophage Uptake of Low Density Lipoprotein after Self‐Aggregation

D. Steinberg, J. Khoo, E. Miller, 1988, Arteriosclerosis.

Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.

D. Steinberg, J. Khoo, E. Miller, 1990, Journal of lipid research.

Feasibility of using an oleate-rich diet to reduce the susceptibility of low-density lipoprotein to oxidative modification in humans.

D. Steinberg, P. Reaven, J. Witztum, 1991, The American journal of clinical nutrition.

Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study

C. Nievergelt, A. Schork, D. O'Connor, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Oxidized phospholipids are present on plasminogen, affect fibrinolysis, and increase following acute myocardial infarction.

M. Koschinsky, J. Witztum, H. Yin, 2012, Journal of the American College of Cardiology.

Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice.

P. Willeit, J. Witztum, M. Graham, 2011, Journal of the American College of Cardiology.

Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events.

P. Talmud, M. Sandhu, N. Wareham, 2010, Journal of the American College of Cardiology.

Relationship of Oxidized Phospholipids on Apolipoprotein B-100 Particles to Race/Ethnicity, Apolipoprotein(a) Isoform Size, and Cardiovascular Risk Factors: Results From the Dallas Heart Study

A. Khera, J. D. de Lemos, E. Brilakis, 2009, Circulation.

Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish

Soo-Ho Choi, R. Klemke, J. Witztum, 2009, Circulation research.

Increased Plasma Oxidized Phospholipid:Apolipoprotein B-100 Ratio With Concomitant Depletion of Oxidized Phospholipids From Atherosclerotic Lesions After Dietary Lipid-Lowering: A Potential Biomarker of Early Atherosclerosis Regression

P. Libby, J. Witztum, D. Heistad, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Oxidized Low-Density Lipoprotein Biomarkers in Patients with End-Stage Renal Failure: Acute Effects of Hemodialysis

S. Tsimikas, E. Miller, M. Bossola, 2007, Blood Purification.

Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin.

P. Ridker, J. Kastelein, J. Witztum, 2006, Journal of the American College of Cardiology.

Percutaneous Coronary Intervention Results in Acute Increases in Oxidized Phospholipids and Lipoprotein(a): Short-Term and Long-Term Immunologic Responses to Oxidized Low-Density Lipoprotein

B. Strauss, J. Witztum, A. Segev, 2004, Circulation.

xidized Low-Density Lipoprotein utoantibodies , Chronic Infections , and arotid Atherosclerosis in a Population-Based Study

Qingbo Xu, S. Kiechl, J. Willeit, 2006 .

Pre-eclampsia and serum antibodies to oxidised low-density lipoprotein

M. Mitchell, D. Branch, E. Miller, 1994, The Lancet.

Antioxidant Vitamins C and E Improve Endothelial Function in Children With Hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial

P. Ridker, J. Morrow, N. Rifai, 2003, Circulation.

Combined Serum Paraoxonase Knockout/Apolipoprotein E Knockout Mice Exhibit Increased Lipoprotein Oxidation and Atherosclerosis*

D. Shih, A. Lusis, L. Castellani, 2000, The Journal of Biological Chemistry.

Alterations in plasma vitamin E distribution in type 2 diabetic patients with elevated plasma phospholipid transfer protein activity.

J. Witztum, P. Gambert, L. Lagrost, 2004, Diabetes.

The transport of alpha-tocopherol and beta-carotene in human blood.

E. Miller, A. Moshell, H. Kayden, 1976, Journal of lipid research.

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study

P. Talmud, N. Wareham, K. Khaw, 2011, Journal of Lipid Research.

High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins.

S. Young, R. E. Pitas, J. Witztum, 2005, Journal of lipid research.

Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice Published, JLR Papers in Press, April 21, 2004. DOI 10.1194/jlr.M400075-JLR200

G. Getz, J. Witztum, L. Blachowicz, 2004, Journal of Lipid Research.

Macrophage Apoptosis Exerts Divergent Effects on Atherogenesis as a Function of Lesion Stage

J. Witztum, E. Miller, E. Gautier, 2008, Circulation.

Cholesterol esterification as a limiting factor in accumulation of cell cholesterol: a comparison of two J774 macrophage cell lines.

W. Rosoff, I. Tabas, J. Khoo, 1989, Biochimica et biophysica acta.

CLINICAL STUDIES Acute Coronary Syndromes Temporal Increases in Plasma Markers of Oxidized Low-Density Lipoprotein Strongly Reflect the Presence of Acute Coronary Syndromes

J. Witztum, S. Tsimikas, E. Miller, 2003 .

Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events Published, JLR Papers in Press, November 8, 2006.

E. Brilakis, J. Witztum, P. Berger, 2007, Journal of Lipid Research.

Inhibition of arterial lesion progression in CD16-deficient mice: evidence for altered immunity and the role of IL-10.

J. Witztum, S. Huber, E. Miller, 2010, Cardiovascular research.

A rapid and sensitive enzymatic-radiochemical assay for the determination of triglycerides.

J. Khoo, E. Miller, D. Goldberg, 1987, Journal of lipid research.

The transport of a-tocopherol and p-carotene in human blood

E. Miller, A. Moshell, H. Kayden, 1976 .

Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes.

E. Miller, E. Miller, W. Palinski, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.

E. Miller, W. Palinski, W Palinski, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Conventional Dendritic Cells at the Crossroads Between Immunity and Cholesterol Homeostasis in Atherosclerosis

F. Ginhoux, J. Witztum, E. Miller, 2009, Circulation.

Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet

R. Krauss, J. Witztum, S. Tsimikas, 2010, Journal of Lipid Research.

The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles.

M. Koschinsky, C. Pullinger, J. Kane, 2010, Atherosclerosis.

Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study.

F. Kronenberg, Qingbo Xu, M. Mayr, 2006, Journal of the American College of Cardiology.

Antisense Oligonucleotide Directed to Human Apolipoprotein B-100 Reduces Lipoprotein(a) Levels and Oxidized Phospholipids on Human Apolipoprotein B-100 Particles in Lipoprotein(a) Transgenic Mice

Mark J Graham, Rosanne M Crooke, R. E. Pitas, 2008, Circulation.

Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes.

Joseph Juliano, J. Witztum, S. Tsimikas, 2003, Journal of the American College of Cardiology.

Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates.

J L Witztum, F. Pio, D. Steinberg, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts.

S. Parthasarathy, J. Khoo, M. Rosenfeld, 1991, The Journal of clinical investigation.

Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects.

D. Steinberg, P. Reaven, S. Parthasarathy, 1993, The Journal of clinical investigation.

High-level lipoprotein [a] expression in transgenic mice: Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.M400467-JLR200evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins

S. Young, J. Witztum, R. Lawn, 2005, Journal of Lipid Research.