Kevin J. Bitterman

Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1*

D. Sinclair, H. Cohen, Rozalyn M. Anderson, 2002, The Journal of Biological Chemistry.

Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase

Myriam Gorospe, R. de Cabo, M. Gorospe, 2004, Science.

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Phuong Chung, Siva Lavu, Dudley Lamming, 2003, Nature.

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.

Hidde Ploegh, Siva Lavu, Benedikt M Kessler, 2004, Molecular cell.

Longevity Regulation in Saccharomyces cerevisiae: Linking Metabolism, Genome Stability, and Heterochromatin

D. Sinclair, Kevin J. Bitterman, Oliver Medvedik, 2003, Microbiology and Molecular Biology Reviews.

Metabolic Regulation of Gene Silencing and Life Span

D. Sinclair, H. Cohen, Kevin J. Bitterman, 2003 .

Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.

D. Sinclair, J. Gordon, H. Cohen, 2013, The Journal of Biological Chemistry.

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

D. Sinclair, Rozalyn M. Anderson, Kevin J. Bitterman, 2003, Nature.

Manipulation of a Nuclear NAD+ Salvage Pathway Delays Aging without Altering Steady-state NAD+ Levels*

D. Sinclair, J. Gordon, H. Cohen, 2002, The Journal of Biological Chemistry.