V. Oganesyan

发表

Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes.

Sung-Hou Kim, H. Yokota, R. Kim, 2004, Acta crystallographica. Section D, Biological crystallography.

Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates

D. Tabor, M. Esser, C. K. Stover, 2018, The Journal of infectious diseases.

Mechanisms of Neutralization of a Human Anti-α-toxin Antibody*

Herren Wu, B. Sellman, V. Oganesyan, 2014, The Journal of Biological Chemistry.

Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody

Jared S. Bee, Herren Wu, S. R. Perry, 2018, The Journal of Biological Chemistry.

A Diene-Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels-Alder Reaction with Maleimide or Proximity-Based Dimerization.

Fengying Huang, M. Marelli, Herren Wu, 2019, Angewandte Chemie.

A Diene‐Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels–Alder Reaction with Maleimide or Proximity‐Based Dimerization

M. Marelli, Herren Wu, R. Christie, 2019, Angewandte Chemie.

A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity

U. Müller-Ladner, Isharat Yusuf, T. Thisted, 2019, Science Translational Medicine.

Structural Genomics of Minimal Organisms and Protein Fold Space

Paul D. Adams, Steven E. Brenner, Stephen R. Holbrook, 2005, Journal of Structural and Functional Genomics.

Molecular basis for antagonistic activity of anifrolumab, an anti-interferon–α receptor 1 antibody

Herren Wu, V. Oganesyan, M. Damschroder, 2015, mAbs.

Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer

Hongbing Shen, D. Shen, Song Wu, 2016, PLoS genetics.

Crystal structure of the human 4-1BB/4-1BBL complex

V. Oganesyan, R. Gilbreth, Shabazz Novarra, 2018, The Journal of Biological Chemistry.

Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models

B. Sellman, P. Warrener, V. Oganesyan, 2018, Antimicrobial Agents and Chemotherapy.

Alanine scanning mutagenesis of the MEDI4839 (Suvratoxumab) epitope reduces alpha toxin lytic activity in vitro and S. aureus fitness in infection models

Yueyue Shi, B. Sellman, P. Warrener, 2018, bioRxiv.

Long-acting antibody ligand mimetics for HER4-selective agonism

Herren Wu, V. Oganesyan, M. Damschroder, 2020, Scientific Reports.

Fibronectin type III domains engineered to bind CD40L: cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of two complexes.

T. Thisted, V. Oganesyan, Stacey Drabic, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of the complex of a human anti-ephrin type-A receptor 2 antibody fragment and its cognate antigen.

Herren Wu, Susan D. Wilson, V. Oganesyan, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of the complex between a human anti-alpha toxin antibody fragment and alpha toxin.

Herren Wu, V. Oganesyan, C. Tkaczyk, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of the complex between a human anti-interferon antibody fragment and human interferon α-2A

Herren Wu, V. Oganesyan, M. Damschroder, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Investigation of inorganic pyrophosphatase from E. coli at a resolution of 5 Å

V. Oganesyan, S. Avaeva, S. Terzyan, 1991 .

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms

Herren Wu, V. Oganesyan, Changshou Gao, 2014, The Journal of Biological Chemistry.

Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab*

Herren Wu, R. Woods, V. Oganesyan, 2015, The Journal of Biological Chemistry.

Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding

Herren Wu, R. Woods, V. Oganesyan, 2015, Acta crystallographica. Section D, Biological crystallography.

In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance

N. V. Dyk, Herren Wu, V. Oganesyan, 2021, Communications Biology.

Generation and Characterization of an IgG4 Monomeric Fc Platform

Jared S. Bee, Herren Wu, V. Oganesyan, 2016, PloS one.

pH-dependent Binding Engineering Reveals an FcRn Affinity Threshold That Governs IgG Recycling

V. Oganesyan, Nurten Beyaz, W. Dall'acqua, 2014, The Journal of Biological Chemistry.

pH-dependent FcRn binding and IgG clearance 1 pH-Dependent Binding Engineering Reveals An FcRn Affinity Threshold Which Governs IgG Recycling

V. Oganesyan, Nurten Beyaz, W. Dall'acqua, 2014 .

Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody.

Herren Wu, V. Oganesyan, M. Damschroder, 2011, Journal of molecular biology.

Structural characterization of a human Fc fragment engineered for extended serum half-life.

Herren Wu, R. Woods, V. Oganesyan, 2009, Molecular immunology.

Structural characterization of a human Fc fragment engineered for lack of effector functions

Lena Shirinian, Herren Wu, Herren Wu, 2008, Acta crystallographica. Section D, Biological crystallography.

Structural characterization of a mutated, ADCC-enhanced human Fc fragment.

Herren Wu, V. Oganesyan, M. Damschroder, 2008, Molecular immunology.

Crystal Structure of the “PhoU-Like” Phosphate Uptake Regulator from Aquifex aeolicus

Sung-Hou Kim, P. Adams, H. Yokota, 2005, Journal of bacteriology.

Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus.

Sung-Hou Kim, P. Adams, R. Kim, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution.

Sung-Hou Kim, P. Adams, H. Yokota, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus.

Sung-Hou Kim, R. Kim, Shengfeng Chen, 2003, Acta crystallographica. Section D, Biological crystallography.

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force*

V. Oganesyan, Padmaja Mehta-D’souza, S. Terzyan, 2016, The Journal of Biological Chemistry.

The Crystal Structure of the Endothelial Protein C Receptor and a Bound Phospholipid*

Zbigniew Dauter, Simon Terzyan, Z. Dauter, 2002, The Journal of Biological Chemistry.

Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893

D. Tabor, T. Slidel, H. Jafri, 2016, Antimicrobial Agents and Chemotherapy.

Mechanisms of Neutralization of a Human Protein Structure and Folding

Dall ' Acqua, Herren Wu, Christine Tkaczyk, 2015 .

1 Mechanisms of Neutralization of a Human Anti-Alpha Toxin Antibody

Herren Wu, B. Sellman, V. Oganesyan, 2014 .

Improving target cell specificity using a novel monovalent bispecific IgG design

Jihong Wang, Chunning Yang, Herren Wu, 2015, mAbs.

Biological Crystallography Structural Characterization of a Human Fc Fragment Engineered for Lack of Effector Functions

Herren Wu, V. Oganesyan, Changshou Gao, 2022 .

Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-Cλ interface

V. Oganesyan, Chunning Yang, V. Aleti, 2023, mAbs.