Markus Tusche

发表

Fibril structure of amyloid-β(1–42) by cryo–electron microscopy

G. Schröder, R. Ravelli, C. López-Iglesias, 2017, Science.

Correction: Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity

C. Teunissen, D. Willbold, L. Gremer, 2016, PloS one.

Comparison of blood‐brain barrier penetration efficiencies between linear and cyclic all‐d‐enantiomeric peptides developed for the treatment of Alzheimer's disease

K. Langen, N. Shah, Nan Jiang, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer’s Disease

K. Langen, N. Shah, D. Willbold, 2018, Journal of Alzheimer's disease : JAD.

QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

Ewa A. Mirecka, A. Janssen, T. van Groen, 2015, Scientific Reports.

Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers

Pitter F. Huesgen, L. Pollegioni, S. Sacchi, 2019, Scientific Reports.

Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization

Peixiang Ma, D. Willbold, Markus Tusche, 2017, Scientific Reports.

Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity

C. Teunissen, D. Willbold, L. Gremer, 2016, PloS one.

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

T. van Groen, I. Kadish, D. Willbold, 2017, Scientific Reports.

Optimization of d-Peptides for Aβ Monomer Binding Specificity Enhances Their Potential to Eliminate Toxic Aβ Oligomers.

T. van Groen, I. Kadish, D. Willbold, 2017, ACS Chemical Neuroscience.

Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease

D. Willbold, B. Hutter-Paier, Markus Tusche, 2017, Molecules.

Increase of Positive Net Charge and Conformational Rigidity Enhances the Efficacy of d-Enantiomeric Peptides Designed to Eliminate Cytotoxic Aβ Species.

T. van Groen, I. Kadish, D. Willbold, 2016, ACS chemical neuroscience.

Oral absorption enhancement of the amyloid-β oligomer eliminating compound RD2 by conjugation with folic acid.

C. Zafiu, Markus Tusche, B. Santiago-Schübel, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

T. van Groen, I. Kadish, D. Willbold, 2017, Scientific Reports.

Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination

E. Wanker, A. Boeddrich, J. Buitenhuis, 2016, PloS one.

Aβ oligomer eliminating compounds interfere successfully with pEAβ(3–42) induced motor neurodegenerative phenotype in transgenic mice

K. Langen, H. Demuth, D. Willbold, 2017, Neuropeptides.

Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers

Pitter F. Huesgen, L. Pollegioni, S. Sacchi, 2019, Scientific Reports.

Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer’s Disease and Other Tauopathies

D. Willbold, W. Hoyer, Markus Tusche, 2023, International journal of molecular sciences.

Design of D-Amino Acids SARS-CoV-2 Main Protease Inhibitors Using the Cationic Peptide from Rattlesnake Venom as a Scaffold

M. Coronado, D. Willbold, R. Arni, 2021, bioRxiv.