G. Allaway

发表

PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing

David E. Martin, E. Freed, J. Orenstein, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Bevirimat: A Novel Maturation Inhibitor for the Treatment of HIV-1 Infection

David E. Martin, K. Salzwedel, G. Allaway, 2008, Antiviral chemistry & chemotherapy.

Susceptibility of Human Immunodeficiency Virus Type 1 to the Maturation Inhibitor Bevirimat Is Modulated by Baseline Polymorphisms in Gag Spacer Peptide 1

L. Stuyver, K. Van Baelen, Y. Verlinden, 2009, Antimicrobial Agents and Chemotherapy.

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5

William C. Olson, A. Trkola, C. Cheng‐Mayer, 1996, Nature.

Determinants of activity of the HIV-1 maturation inhibitor PA-457.

David E. Martin, E. Freed, K. Salzwedel, 2006, Virology.

Potent Activity of the HIV-1 Maturation Inhibitor Bevirimat in SCID-hu Thy/Liv Mice

David E. Martin, J. C. Bare, G. Allaway, 2007, PloS one.

Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates.

R. Koup, G. A. Beaudry, K. Hasel, 1995, AIDS research and human retroviruses.

Synergistic inhibition of HIV-1 envelope-mediated cell fusion by CD4-based molecules in combination with antibodies to gp120 or gp41.

G. A. Beaudry, G. Allaway, P. Maddon, 1993, AIDS research and human retroviruses.

A Potential for Mutual Regulation of Proopiomelanocortin Gene and Epstein‐Barr Virus Expression in Human Lymphocytes

B. Prabhakar, G. Allaway, E. Oates, 1990, Annals of the New York Academy of Sciences.

Characterization of the 70KDA component of the human Ku autoantigen expressed in insect cell nuclei using a recombinant baculovirus vector.

B. Prabhakar, A. Notkins, G. Allaway, 1990, Biochemical and biophysical research communications.

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.

Li Huang, Chin-Ho Chen, Keduo Qian, 2009, Journal of medicinal chemistry.

Human immunodeficiency virus type 1 membrane fusion mediated by a laboratory-adapted strain and a primary isolate analyzed by resonance energy transfer

C. Chang, K. Hasel, W. Olson, 1996, Journal of virology.

Human lymphocytes produce pro-opiomelanocortin gene-related transcripts. Effects of lymphotropic viruses.

B. Prabhakar, J. Kehrl, G. Allaway, 1988, The Journal of biological chemistry.

Host range and virulence of five baculoviruses from lepidopterous hosts.

G. Allaway, C. Payne, 1984 .

Design and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist

S. Biswal, H. Mansour, G. Allaway, 2020, Scientific Reports.

Anti-HIV agents. Part 55: 3'R,4'R-Di-(O)-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP), a novel anti-HIV agent.

A. Brossi, K. Lee, N. Kilgore, 2003, Bioorganic & medicinal chemistry letters.

Anti-AIDS agents. Part 47: Synthesis and anti-HIV activity of 3-substituted 3',4'-Di-O-(S)-camphanoyl-(3'R,4'R)-(+)-cis-khellactone derivatives.

K. Lee, N. Kilgore, G. Allaway, 2001, Bioorganic & medicinal chemistry letters.

The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV

David E. Martin, Chin-Ho Chen, K. Lee, 2005, Expert opinion on investigational drugs.

Phase I and II Study of the Safety, Virologic Effect, and Pharmacokinetics/Pharmacodynamics of Single-Dose 3-O-(3′,3′-Dimethylsuccinyl)Betulinic Acid (Bevirimat) against Human Immunodeficiency Virus Infection

David E. Martin, Judy Doto, Patrick F. Smith, 2007, Antimicrobial Agents and Chemotherapy.

Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry

William C. Olson, Thomas P. Sakmar, A. Trkola, 1998, Journal of Virology.

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

Virginia Litwin, Charmagne Cayanan, R. Koup, 1996, Nature.

Computational Studies and Drug Design for HIV-1 Reverse Transcriptase Inhibitors of 3′,4′-di-O-(S)-camphanoyl-(+)-cis-Khellactone (DCK) Analogs

Haifeng Chen, Ting Zhou, Chenyang Zhao, 2005, J. Comput. Aided Mol. Des..

CD4-Immunoglobulin G2 Protects Hu-PBL-SCID Mice against Challenge by Primary Human Immunodeficiency Virus Type 1 Isolates

R. Koup, Paul J Maddon, W. Olson, 1998, Journal of Virology.

Dynamics of Baculovirus Growth and Dispersal in Mamestra brassicae L. (LepidopteraNoctuidae) Larval Populations Introduced into Small Cabbage Plots

G. Allaway, H. Evans, 1983, Applied and environmental microbiology.

Infectivity of some occluded insect viruses

G. Allaway, 1982 .

A biochemical and biological comparison of three European isolates of nuclear polyhedrosis viruses from Agrotis segetum.

G. Allaway, C. Payne, 1983, Archives of virology.

Virus particle packaging in baculovirus and cytoplasmic polyhedrosis virus inclusion bodies

G. Allaway, 1983 .

Chapter 13:From Natural Product to Clinical Trials: Bevirimat, a Plant-Derived Anti-AIDS Drug

Keduo Qian, K. Lee, G. Allaway, 2009 .

Cell surface expression of the 70-kD component of Ku, a DNA-binding nuclear autoantigen.

B. Prabhakar, J. Srinivasappa, A. Notkins, 1990, The Journal of clinical investigation.

Analysis of the bond between encephalomyocarditis virus and its human erythrocyte receptor by affinity chromatography on virus-sepharose columns.

G. Allaway, A. T. Burness, A. Burness, 1987, The Journal of general virology.

Prokaryotic expression of the thyrotropin receptor and identification of an immunogenic region of the protein using synthetic peptides.

B. Prabhakar, T. Akamizu, G. S. Seetharamaiah, 1991, Biochemical and biophysical research communications.

Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG

A. Trkola, C. Barbas, B. Korber, 1995, Journal of virology.

Direct Evidence that C-Peptide Inhibitors of Human Immunodeficiency Virus Type 1 Entry Bind to the gp41 N-Helical Domain in Receptor-Activated Viral Envelope

K. Salzwedel, N. Kilgore, M. Reddick, 2003, Journal of Virology.

Effective ex vivo neutralization of human immunodeficiency virus type 1 in plasma by recombinant immunoglobulin molecules

C. Barbas, D. Burton, R. Koup, 1996, Journal of virology.

Spontaneously proliferating human B lymphocytes make autoantibodies.

B. Prabhakar, F. Miller, J. Srinivasappa, 1988, The Journal of infectious diseases.

A biochemical and biological comparison of three European isolates of nuclear polyhedrosis viruses fromAgrotis segetum

G. Allaway, C. Payne, 2005, Archives of Virology.

Aggregation of encephalomyocarditis virus induced by radio-iodination.

G. Allaway, I. Pardoe, A. T. Burness, 1986, Journal of virological methods.

Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation.

K. Salzwedel, N. Kilgore, D. Zoumplis, 2010, Virology.

Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives.

Keduo Qian, K. Lee, N. Kilgore, 2007, Bioorganic & medicinal chemistry letters.

Increase in sensitivity to soluble CD4 by primary HIV type 1 isolates after passage through C8166 cells: association with sequence differences in the first constant (C1) region of glycoprotein 120.

G. Allaway, C. Bandea, J. Mcdougal, 1995, AIDS research and human retroviruses.

Nrf2 exerts cell‐autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative

S. Biswal, W. Tourtellotte, J. Varga, 2017, Translational research : the journal of laboratory and clinical medicine.

Anti-AIDS agents. 52. Synthesis and anti-HIV activity of hydroxymethyl (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone derivatives.

K. Lee, G. Allaway, C. Wild, 2004, Journal of medicinal chemistry.

Development of Bevirimat (PA-457): first-in-class HIV maturation inhibitor

G. Allaway, 2006, Retrovirology.

Susceptibility of Diverse HIV-1 Patient Isolates to the Maturation Inhibitor, Bevirimat (MPC-4326*), is Determined by Clade- Specific Polymorphisms in Gag CA-SP1

David E. Martin, François Hamy, T. Klimkait, 2009 .

AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor

J. Moore, T. Sakmar, D. Schols, 1998, Nature Medicine.

Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy.

S. Biswal, K. Korzekwa, W. Childers, 2015, Bioorganic & medicinal chemistry.

Autoantibody Production by Human B Lymphocytes which Spontaneously Proliferate

B. Prabhakar, F. Miller, J. Srinivasappa, 1987 .

Site of attachment of encephalomyocarditis virus on human erythrocytes

G. Allaway, A. Burness, 1986, Journal of virology.