M. LaVoie

发表

Molecular Map of the Chlamydomonas reinhardtii Nuclear Genome

P. Lefebvre, C. Silflow, W. Brazelton, 2003, Eukaryotic Cell.

The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax

M. LaVoie, B. Johnson, Alison K Berger, 2012, Proceedings of the National Academy of Sciences.

The Notch Ligands, Jagged and Delta, Are Sequentially Processed by α-Secretase and Presenilin/γ-Secretase and Release Signaling Fragments*

D. Selkoe, M. LaVoie, Dennis J. Selkoe, 2003, Journal of Biological Chemistry.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis

Junying Yuan, Yasushi Ito, D. Ofengeim, 2018, Proceedings of the National Academy of Sciences.

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins.

D. Selkoe, D. Walsh, J. Fadeeva, 2003, Biochemistry.

Assembly of the γ-Secretase Complex Involves Early Formation of an Intermediate Subcomplex of Aph-1 and Nicastrin*

D. Selkoe, M. Wolfe, W. Kimberly, 2003, Journal of Biological Chemistry.

Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates.

D. Selkoe, M. Wolfe, W. Kimberly, 2003, Neurobiology of disease.

Aggregation Diseases ndProteostasis to Ameliorate Protein Misfolding a Chemical and Biological Approaches for Adapting

S. Kaushal, C. Dobson, D. A. Bosco, 2011 .

Functional γ-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and γ-secretase substrates

D. Selkoe, M. Wolfe, W. Kimberly, 2003, Neurobiology of Disease.

Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons

J. Schapansky, J. Nardozzi, Tim Bartels, 2018, Neurobiology of Disease.

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

T. Schwarz, M. LaVoie, G. Ashrafi, 2014, The Journal of cell biology.

Genetic deletion of the GATA1‐regulated protein α‐synuclein reduces oxidative stress and nitric oxide synthase levels in mature erythrocytes

David A. Williams, D. Selkoe, M. LaVoie, 2014, American journal of hematology.

Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation

T. Vogt, J. Davila-Velderrain, Fan Gao, 2020, Neuron.

Lysosome and Inflammatory Defects in GBA1‐Mutant Astrocytes Are Normalized by LRRK2 Inhibition

M. Tansey, J. Tomlinson, M. LaVoie, 2020, Movement disorders : official journal of the Movement Disorder Society.

Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity

J. P. Card, M. LaVoie, T. Hastings, 2004, Experimental Neurology.

Peroxynitrite‐ and Nitrite‐Induced Oxidation of Dopamine : Implications for Nitric Oxide in Dopaminergic Cell Loss

M. LaVoie, T. Hastings, 1999, Journal of neurochemistry.

Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin

J. Nardozzi, M. LaVoie, R. Charan, 2014, Cell Death and Disease.

JCB_201401070 1..16

T. Schwarz, M. LaVoie, G. Ashrafi, 2014 .

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK 1 and

T. Schwarz, M. LaVoie, G. Ashrafi, 2014 .

Aph-1 Associates Directly with Full-length and C-terminal Fragments of γ-Secretase Substrates

D. Selkoe, M. LaVoie, B. Ostaszewski, 2010, The Journal of Biological Chemistry.

Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex.

D. Selkoe, M. Wolfe, W. Kimberly, 2004, Biochemistry.

Complex N-linked Glycosylated Nicastrin Associates with Active γ-Secretase and Undergoes Tight Cellular Regulation*

D. Selkoe, M. Wolfe, W. Kimberly, 2002, The Journal of Biological Chemistry.

Identification of intrinsic dimer and overexpressed monomeric forms of gamma-tubulin in Sf9 cells infected with baculovirus containing the Chlamydomonas gamma-tubulin sequence.

A. Vassilev, C. Silflow, M. Kimble, 1995, Journal of cell science.

Identification of intrinsic dimer and overexpressed monomeric forms of γ-tubulin in Sf9 cells infected with baculovirus containing the Chlamydomonas

A. Vassilev, C. Silflow, M. Kimble, 1995 .

Dopamine Quinone Formation and Protein Modification Associated with the Striatal Neurotoxicity of Methamphetamine: Evidence against a Role for Extracellular Dopamine

M. LaVoie, T. Hastings, 1999, The Journal of Neuroscience.

Dopamine covalently modifies and functionally inactivates parkin

D. Selkoe, A. Weihofen, M. LaVoie, 2005, Nature Medicine.

The production of high affinity monoclonal antibodies to human chorionic gonadotropin and their application to immunoradiometric assay.

J. Côté, M. LaVoie, P. Du Ruisseau, 1986, Journal of immunoassay.

Is there a special relationship between complex I activity and nigral neuronal loss in Parkinson’s disease? A critical reappraisal

M. LaVoie, Nitya Subrahmanian, 2021, Brain Research.

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

Xinnan Wang, D. Selkoe, T. Schwarz, 2011, Cell.

Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.

G. Petsko, D. Ringe, D. A. Bosco, 2011, Cold Spring Harbor perspectives in biology.

Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release.

A. Letai, A. Weihofen, M. LaVoie, 2009, Human molecular genetics.

Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

David S. Park, R. Padmore, D. Philpott, 2011, Journal of Neural Transmission.

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease.

David S. Park, Y. Rao, R. Slack, 2009, Human molecular genetics.

Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with α‐synuclein genotype

D. Selkoe, H. Brown, P. Ivanova, 2009, Journal of neurochemistry.

The Vfl1 Protein in Chlamydomonas Localizes in a Rotationally Asymmetric Pattern at the Distal Ends of the Basal Bodies

M. Borodovsky, P. Lefebvre, C. Silflow, 2001, The Journal of cell biology.

The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson’s disease

J. Schapansky, J. Nardozzi, M. LaVoie, 2015, Neuroscience.

Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy.

J. Schapansky, J. Nardozzi, M. LaVoie, 2014, Human molecular genetics.

Gamma-tubulin in Chlamydomonas: characterization of the gene and localization of the gene product in cells.

C. Silflow, B. Liu, M. LaVoie, 1999, Cell motility and the cytoskeleton.

The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.

D. Selkoe, M. LaVoie, Dennis J Selkoe, 2003, The Journal of biological chemistry.

Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation.

Z. Berger, M. LaVoie, Kelsey A. Smith, 2010, Biochemistry.

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

Michael S. Wolfe, D. Selkoe, M. Wolfe, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The Uni2 phosphoprotein is a cell cycle regulated component of the basal body maturation pathway in Chlamydomonas reinhardtii.

P. Lefebvre, C. Silflow, L. Tam, 2008, Molecular biology of the cell.

The effects of oxidative stress on parkin and other E3 ligases

M. LaVoie, M. Schlossmacher, Giuseppe P. Cortese, 2007, Journal of neurochemistry.

Pathologic and therapeutic implications for the cell biology of parkin

M. LaVoie, Rakshita A. Charan, 2015, Molecular and Cellular Neuroscience.

Purification and characterization of the human gamma-secretase complex.

Rong Wang, Georgia Dolios, D. Selkoe, 2004, Biochemistry.

γ-Secretase Substrate Selectivity Can Be Modulated Directly via Interaction with a Nucleotide-binding Site*

D. Selkoe, M. Wolfe, M. LaVoie, 2005, Journal of Biological Chemistry.

Misfolding Disorders Protein Solubility and Protein Homeostasis : A Generic View of Protein

M. Retzlaff, T. Tatsuta, T. Knowles, 2011 .

LRRK2 Kinase Inhibition Rescues Deficits in Lysosome Function Due to Heterozygous GBA1 Expression in Human iPSC-Derived Neurons

M. LaVoie, Anwesha Sanyal, Hailey S. Novis, 2020, Frontiers in Neuroscience.

Parkinson Disease-Linked Parkin Mediates Redox Reactions That Lower Oxidative Stress In Mammalian Brain

David S. Park, N. Hattori, C. Palmberg, 2020, bioRxiv.

The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress

Kelsey P. Taylor, M. LaVoie, M. Journel, 2013, Neurobiology of Disease.

Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain

W. Xia, S. Baulac, M. LaVoie, 2004, Molecular and Cellular Neuroscience.

Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility

T. Schwarz, J. Schapansky, M. LaVoie, 2016, Proceedings of the National Academy of Sciences.

Evidence that alpha-synuclein does not inhibit phospholipase D.

D. Selkoe, S. Lindquist, A. Gitler, 2009, Biochemistry.

Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

A. Beilina, A. Mamais, A. Kaganovich, 2021, PLoS biology.

The LRRK2 kinase substrates Rab8a and Rab10 contribute complementary but distinct disease-relevant phenotypes in human neurons

A. Mamais, M. LaVoie, W. Gibbs, 2023, bioRxiv.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Parkin coregulates glutathione metabolism in adult mammalian brain

N. Hattori, C. Palmberg, B. Shutinoski, 2023, Acta Neuropathologica Communications.

Evidence that α -Synuclein Does Not Inhibit Phospholipase D †

D. Selkoe, S. Lindquist, A. Gitler, 2009 .