Steffen Jaensch

发表

Molecular mechanism of respiratory syncytial virus fusion inhibitors.

L. Kwanten, J. McLellan, D. Roymans, 2016, Nature chemical biology.

Limiting Amounts of Centrosome Material Set Centrosome Size in C. elegans Embryos

E. Myers, A. Hyman, K. O’Connell, 2011, Current Biology.

Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor

L. Kwanten, J. McLellan, P. Rigaux, 2017, Nature Communications.

Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles

A. Hyman, F. Jülicher, David Zwicker, 2014, Proceedings of the National Academy of Sciences.

Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines

Hinrich W. H. Göhlmann, Jean-Marc Neefs, Yolanda T. Chong, 2020, Scientific Reports.

Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines

Yolanda T. Chong, J. Neefs, Michael J. Cox, 2020, Scientific Reports.

Time-Resolved Quantification of Centrosomes by Automated Image Analysis Suggests Limiting Component to Set Centrosome Size in C. Elegans Embryos

Steffen Jaensch, 2010 .

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

J. Reumers, R. de Hoogt, A. Buist, 2018, Stem cell reports.

Development of a cellular high-content, immunofluorescent HBV core assay to identify novel capsid assembly modulators that induce the formation of aberrant HBV core structures.

Emmanuel Gustin, F. Pauwels, D. Peeters, 2021, Journal of virological methods.

Discovery of JNJ-63576253, a Next-Generation Androgen Receptor Antagonist Active Against Wild-Type and Clinically Relevant Ligand Binding Domain Mutations in Metastatic Castration-Resistant Prostate Cancer

Yolanda T. Chong, T. Bush, G. Bignan, 2021, Molecular Cancer Therapeutics.

Title: Discovery of JNJ-63576253, a next-generation androgen receptor antagonist active against wild- type and clinically-relevant ligand binding domain mutations in metastatic castration-resistant prostate cancer (mCRPC) Running Title: Discovery of JNJ-63576253, a next-generation AR antagonist

Yolanda T. Chong, T. Bush, G. Bignan, 2021 .

Remodeling oncogenic transcriptomes by small molecules targeting NONO

B. Cravatt, S. Blue, Hsuan-Lin Her, 2023, Nature Chemical Biology.

Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor

J. McLellan, P. Rigaux, D. Roymans, 2017, Nature Communications.

Centrosome Size Sets Mitotic Spindle Length in Caenorhabditis elegans Embryos

Anthony A. Hyman, Frank Jülicher, Clifford P. Brangwynne, 2010, Current Biology.

Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy.

Willem Talloen, Bie M. P. Verbist, Freddy Van Goethem, 2015, Chemical research in toxicology.

Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids

Michaël Barbier, Steffen Jaensch, Yolanda T. Chong, 2016, PloS one.

Identification of Z-Tyr-Ala-CHN2, a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2

Michiel Van Gool, S. Ciesek, Christophe Buyck, 2023, Microorganisms.

Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos

Eugene W. Myers, Anthony A. Hyman, Steffen Jaensch, 2010, Bioinform..

Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models

Emmanuel Gustin, J. Reumers, P. Peeters, 2023, Chemical research in toxicology.

JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations

Anne E Carpenter, Lewis H. Mervin, Patrick W. Faloon, 2023, bioRxiv.

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

J. Reumers, R. de Hoogt, A. Buist, 2019, Stem cell reports.

Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles

A. Hyman, F. Jülicher, David Zwicker, 2014, Proceedings of the National Academy of Sciences.