H. Kyle

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Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation

Rachel L. Dods, J. Éléouët, T. Edwards, 2014, Proceedings of the National Academy of Sciences.

Towards “bionic” proteins: replacement of continuous sequences from HIF-1α with proteomimetics to create functional p300 binding HIF-1α mimics† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterisation; additional biophysical data. See DOI: 10.1039/

A. Breeze, S. Warriner, A. Nelson, 2016, Chemical communications.

Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6ob00078a Click here for additional data file.

A. Breeze, S. Warriner, A. Nelson, 2016, Organic & biomolecular chemistry.

Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions

A. Nelson, Andrew J. Wilson, T. Edwards, 2017, Chemical science.

Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies.

A. Breeze, S. Warriner, A. Nelson, 2015, Molecular bioSystems.

Small-Molecule Proteomimetic Inhibitors of the HIF-1α–p300 Protein–Protein Interaction

A. Breeze, S. Warriner, A. Nelson, 2014, Chembiochem : a European journal of chemical biology.

Affimer proteins are versatile and renewable affinity reagents

Filomena Esteves, Alistair Curd, Marisa Martin-Fernandez, 2017, eLife.

Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs**

J. Clarke, Andrew J. Wilson, T. Edwards, 2020, Chembiochem : a European journal of chemical biology.

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

J. Clarke, Andrew J. Wilson, T. Edwards, 2019, bioRxiv.

Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation

Rachel L. Dods, J. Éléouët, T. Edwards, 2014, Proceedings of the National Academy of Sciences.

Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions

A. Nelson, Andrew J. Wilson, T. Edwards, 2017, Chemical science.

Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies.

A. Breeze, S. Warriner, A. Nelson, 2015, Molecular bioSystems.