I. Darby

发表

Aspirin treatment for chronic wounds: Potential beneficial and inhibitory effects

C. Weller, I. Darby, 2017, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Osteopontin expression in normal and fibrotic liver. altered liver healing in osteopontin-deficient mice.

A. Desmoulière, I. Darby, S. Rittling, 2006, Journal of hepatology.

Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.

A. Desmoulière, I. Darby, M Redard, 1995, The American journal of pathology.

Erythropoietin gene expression in fetal and adult sheep kidney

E. Wintour, P. Fu, I. Darby, 1995, British journal of haematology.

Cytoskeletal protein flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression

D. Murrell, Z. Kopecki, A. Cowin, 2015, Oncotarget.

Increased density of renal amylin binding sites in experimental hypertension.

M. Voskuil, M. Cooper, R. Komers, 1997, Hypertension.

Sox18 Is Transiently Expressed during Angiogenesis in Granulation Tissue of Skin Wounds with an Identical Expression Pattern to Flk-1 mRNA

G. Muscat, P. Koopman, I. Darby, 2001, Laboratory Investigation.

Proteomic Analysis of Differentially Expressed Proteins in Peripheral Cholangiocarcinoma

S. Lepreux, C. Balabaud, P. Bioulac-Sage, 2011, Cancer Microenvironment.

Skeletal myocytes are a source of interleukin‐6 mRNA expression and protein release during contraction: evidence of fiber type specificity

M. Febbraio, I. Darby, N. Hiscock, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cardioprotection from ischaemia-reperfusion injury by a novel flavonol that reduces activation of p38 MAPK.

C. May, O. Woodman, I. Darby, 2011, European journal of pharmacology.

In situ localization of apoptosis using TUNEL.

I. Darby, T. Hewitson, 2010, Methods in molecular biology.

In situ hybridization protocols

I. Darby, 1999 .

The Role of the Myofibroblast in Fibrosis and Cancer Progression

B. Hinz, A. Desmoulière, G. Gabbiani, 2011 .

Self-Assembled Peptide Habitats to Model Tumor Metastasis

D. Nisbet, Rasika M. Samarasinghe, D. Pouniotis, 2022, Gels.

Characterization of M1/M2 Tumour-Associated Macrophages (TAMs) and Th1/Th2 Cytokine Profiles in Patients with NSCLC

C. McDonald, D. Pouniotis, I. Darby, 2016, Cancer Microenvironment.

Human renal fibroblast contraction of collagen I lattices is an integrin-mediated process.

G. Becker, K. Nicholls, I. Darby, 2000, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Siah2‐deficient mice show impaired skin wound repair

D. Bowtell, A. Möller, P. Little, 2013, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Fibrillin-1 expression in normal and fibrotic rat liver and in cultured hepatic fibroblastic cells: modulation by mechanical stress and role in cell adhesion

A. Desmoulière, V. Sapin, D. Reinhardt, 2004, Laboratory Investigation.

Evolution of tubulointerstitial fibrosis in experimental renal infection and scarring.

G. Becker, I. Darby, C. Jones, 1998, Journal of the American Society of Nephrology : JASN.

Apoptosis is increased in a model of diabetes-impaired wound healing in genetically diabetic mice.

I. Darby, T. Hewitson, D. Maclellan, 1997, International Journal of Biochemistry and Cell Biology.

Histochemical localization of apoptosis with in situ labeling of fragmented DNA.

I. Darby, T. Hewitson, T. Bisucci, 2006, Methods in molecular biology.

Skin flap‐induced regression of granulation tissue correlates with reduced growth factor and increased metalloproteinase expression

A. Desmoulière, G. Gabbiani, I. Darby, 2002, The Journal of pathology.

In situ end-labeling of fragmented DNA and the localization of apoptosis.

I. Darby, T. Hewitson, T. Bisucci, 2000, Methods in molecular biology.

The cross-link breaker, N-phenacylthiazolium bromide prevents vascular advanced glycation end-product accumulation

M. Cooper, J. Forbes, I. Darby, 2000, Diabetologia.

Matrix protein glycation impairs agonist‐induced intracellular Ca2+ signaling in endothelial cells

M. Hill, I. Darby, T. Murphy, 2002, Journal of cellular physiology.

Examination of ‘lipotoxicity’ in skeletal muscle of high‐fat fed and ob/ob mice

A. Hevener, B. Kemp, R. Southgate, 2009, The Journal of physiology.

In Situ Hybridization

I. Darby, T. Hewitson, 1989 .

Thyroid hormone receptors and stimulation of angiotensinogen production in HepG2 cells

P. Corvol, I. Darby, E. Coezy, 2007, In Vitro Cellular & Developmental Biology - Animal.

Approaches for introducing peptides into intact and functional arteriolar smooth muscle: manipulation of protein kinase‐based signalling ‡

M. Hill, I. Darby, T. Murphy, 2003, Clinical and experimental pharmacology & physiology.

Quantitation of in situ hybridization using image analysis of radioactively labeled RNA probes.

I. Darby, T. Hewitson, T. Bisucci, 2002, Methods in molecular biology.

USE OF SYNTHETIC OLIGONUCLEOTIDE AND RECOMBINANT DNA PROBES TO STUDY RENIN GENE EXPRESSION

R. Fernley, G. Ryan, I. Darby, 1985, Clinical and experimental pharmacology & physiology.

Impaired Nitric Oxide Function in the Basilar Artery of the Obese Zucker Rat

I. Darby, M. Rand, J. Reid, 2003, Journal of cardiovascular pharmacology.

Explanting Is an ExVivo Model of Renal Epithelial-Mesenchymal Transition

G. Becker, D. Pouniotis, I. Darby, 2014 .

Explanting Is an Ex Vivo Model of Renal Epithelial-Mesenchymal Transition

G. Becker, D. Pouniotis, I. Darby, 2011, Journal of biomedicine & biotechnology.

Aspirin in venous leg ulcer study (ASPiVLU): study protocol for a randomised controlled trial

J. Madan, J. McNeil, M. Underwood, 2016, Trials.

Protection against reperfusion injury by 3',4'-dihydroxyflavonol in rat isolated hearts involves inhibition of phospholamban and JNK2.

O. Woodman, I. Darby, Dominic C. H. Ng, 2018, International journal of cardiology.

Amylin as a growth factor during fetal and postnatal development of the rat kidney.

M. Cooper, C. Tikellis, D. Casley, 1998, Kidney international.

Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat.

P. Sommer, A. Desmoulière, G. Gabbiani, 1997, Laboratory investigation; a journal of technical methods and pathology.

HYBRIDIZATION HISTOCHEMISTRY - LOCATING GENE EXPRESSION

I. Darby, J. Haralambidis, G. Tregear, 1986 .

Histology Protocols

I. Darby, T. Hewitson, J. Walker, 2010, Methods in Molecular Biology.

Temporal variation in the deposition of different types of collagen within a porous biomaterial implant.

J. Werkmeister, J. Ramshaw, I. Darby, 2014, Journal of biomedical materials research. Part A.

Scar Formation: Cellular Mechanisms

A. Desmoulière, I. Darby, 2020, Textbook on Scar Management.

Influence of Gold Nanoparticles on Radiation Dose Enhancement and Cellular Migration in Microbeam-Irradiated Cells

N. Yagi, V. Bansal, I. Darby, 2011 .

Pulmonary delivery of TH9507, a growth hormone releasing factor analogue, in the dog.

T. Abribat, I. Darby, J. Hardy, 2004, International journal of pharmaceutics.

Relaxin down-regulates renal fibroblast function and promotes matrix remodelling in vitro.

G. Becker, L. Parry, I. Darby, 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Intracellular Cyclic Nucleotide Analogues Inhibit in vitro Mitogenesis and Activation of Fibroblasts Derived from Obstructed Rat Kidneys

G. Becker, I. Darby, T. Bisucci, 2004, Nephron Experimental Nephrology.

Cellular and ultrastructural location of angiotensinogen in rat and sheep kidney.

R. Fernley, I. Darby, C. Sernia, 1994, Kidney international.

Fibroblasts and myofibroblasts in wound healing

A. Desmoulière, F. Bonte, I. Darby, 2014, Clinical, cosmetic and investigational dermatology.

Fibroblast differentiation in wound healing and fibrosis.

I. Darby, T. Hewitson, 2007, International review of cytology.

Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.

G. Gabbiani, I. Darby, O. Skalli, 1990, Laboratory investigation; a journal of technical methods and pathology.

The myofibroblast, multiple origins for major roles in normal and pathological tissue repair

B. Coulomb, A. Desmoulière, I. Darby, 2012, Fibrogenesis & tissue repair.

The myofibroblast, a key cell in normal and pathological tissue repair

A. Desmoulière, I. Darby, F. Billet, 2016, Cellular and Molecular Life Sciences.

The biology of a tumour stroma

S. Lepreux, A. Desmoulière, C. Guyot, 2007 .

Role of the phosphatidylinositol 3-kinase and mTOR pathways in the regulation of renal fibroblast function and differentiation.

G. Becker, I. Darby, C. Winbanks, 2007, The international journal of biochemistry & cell biology.

Cautionary note on the use of end‐labelling DNA fragments for detection of apoptosis

I. Darby, P. Fuller, M. Wolvekamp, 1998, Pathology.

Quantitative proteomics of bronchoalveolar lavage fluid in lung adenocarcinoma.

C. McDonald, D. Pouniotis, I. Darby, 2015, Cancer genomics & proteomics.

Renin gene expression in vessels of the ovine renal cortex.

R. Fernley, G. Ryan, I. Darby, 1985, Journal of hypertension.

Hypoxia and hypoxia signaling in tissue repair and fibrosis.

I. Darby, T. Hewitson, Z. Lokmic, 2012, International review of cell and molecular biology.

Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance.

M. Febbraio, G. Lancaster, M. Watt, 2006, American journal of physiology. Endocrinology and metabolism.

Normal and Pathologic Soft Tissue Remodeling: Role of the Myofibroblast, with Special Emphasis on Liver and Kidney Fibrosis

A. Desmoulière, G. Gabbiani, I. Darby, 2003, Laboratory Investigation.

In situ hybridization using cRNA probes: isotopic and nonisotopic detection methods.

A. Desmoulière, I. Darby, T. Hewitson, 2006, Methods in molecular biology.

Hybridization histochemistry.

E. Wintour, I. Darby, J. Haralambidis, 1987, Experientia.

Hybridization histochemistry

E. Wintour, I. Darby, J. Haralambidis, 2005, Experientia.

Inhibition of angiotensinogen production by angiotensin II analogues in human hepatoma cell line.

P. Corvol, E. Escher, I. Darby, 1989, The American journal of physiology.

Hypoxia in tissue repair and fibrosis

I. Darby, T. Hewitson, Ian A. Darby, 2016, Cell and Tissue Research.

Time course analysis of hypoxia, granulation tissue and blood vessel growth, and remodeling in healing rat cutaneous incisional primary intention wounds

Geraldine M Mitchell, Erik W Thompson, Zerina Lokmic, 2006, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

In situ hybridization and immunohistochemistry of renal angiotensinogen in neonatal and adult rat kidneys

I. Darby, C. Sernia, 1995, Cell and Tissue Research.

The myofibroblast, a key cell in normal and pathological tissue repair

A. Desmoulière, I. Darby, F. Billet, 2015, Cellular and Molecular Life Sciences.

Hypoxia in tissue repair and fibrosis

I. Darby, T. Hewitson, 2016, Cell and Tissue Research.

Calcitonin Receptor Expression in Embryonic, Foetal and Adult Tissues: Developmental and Pathophysiological Implications

A. Schwarer, A. Y. Leung, P. Wookey, 2010 .

Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer.

C. McDonald, D. Pouniotis, I. Darby, 2014, World journal of clinical oncology.

Using in situ hybridisation to localize renal gene expression in tissue sections.

A. Desmoulière, I. Darby, T. Hewitson, 2009, Methods in molecular biology.