K. Kajimoto

发表

Difference in intracellular temperature rise between matured and precursor brown adipocytes in response to uncoupler and β-adrenergic agonist stimuli

S. Uchiyama, Toshikazu Tsuji, K. Ikado, 2017, Scientific Reports.

In vivo transdermal delivery of diclofenac by ion-exchange iontophoresis with geraniol.

K. Kanamura, K. Kogure, K. Kajimoto, 2009, Biological & pharmaceutical bulletin.

Noninvasive delivery of siRNA into the epidermis by iontophoresis using an atopic dermatitis-like model rat.

K. Kanamura, K. Kogure, S. Hama, 2010, International journal of pharmaceutics.

Cell penetrating peptide-mediated systemic siRNA delivery to the liver.

J. Yamauchi, I. Khalil, H. Harashima, 2011, International journal of pharmaceutics.

New Design Strategies for Controlling the Rate of Hydrophobic Drug Release from Nanoemulsions in Blood Circulation.

H. Harashima, Saed Abbasi, Yusuke Sato, 2020, Molecular pharmaceutics.

Critical parameters dictating efficiency of membrane‐mediated drug transfer using nanoparticles

H. Harashima, Saed Abbasi, K. Kajimoto, 2018, International journal of pharmaceutics.

Efficiency of cell-free protein synthesis based on a crude cell extract from Escherichia coli, wheat germ, and rabbit reticulocytes.

Y. Baba, Takenori Yamamoto, Y. Shinohara, 2008, Journal of biotechnology.

Ribonuclease protection assay on microchip electrophoresis.

Y. Baba, Masahiro Watanabe, Y. Shinohara, 2011, The Analyst.

Determination of human blood glucose levels using microchip electrophoresis

Noritada Kaji, Manabu Tokeshi, Yasuo Shinohara, 2007, Electrophoresis.

Assessment of MEF2A mutations in myocardial infarction in Japanese patients.

H. Nonogi, N. Iwai, H. Tomoike, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Activation of neuregulin-4 in adipocytes improves metabolic health by enhancing adipose tissue angiogenesis.

K. Hirata, K. Kajimoto, N. Emoto, 2018, Biochemical and biophysical research communications.

Lipid envelope-type nanoparticle incorporating a multifunctional peptide for systemic siRNA delivery to the pulmonary endothelium.

Takahiro Nomoto, Y. Matsumoto, K. Kataoka, 2013, ACS nano.

Development of a quantitative, portable, and automated fluorescent blue-ray device-based malaria diagnostic equipment with an on-disc SiO2 nanofiber filter

J. Ohashi, N. Minakawa, S. Munga, 2020, Scientific Reports.

Field evaluation of a quantitative, and rapid malaria diagnostic system using a fluorescent Blue-ray optical device

J. Ohashi, N. Minakawa, S. Munga, 2019, bioRxiv.

An apolipoprotein E modified liposomal nanoparticle: ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells.

H. Harashima, Yusuke Sato, H. Akita, 2014, International journal of pharmaceutics.

Therapeutic assessment of cytochrome C for the prevention of obesity through endothelial cell-targeted nanoparticulate system.

H. Harashima, H. Akita, K. Kajimoto, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Leptin-derived peptide, a targeting ligand for mouse brain-derived endothelial cells via macropinocytosis.

T. Fujiwara, H. Harashima, H. Akita, 2010, Biochemical and biophysical research communications.

Instructions for use Title Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3 T 3L 1 adipocytes

H. Harashima, K. Kajimoto, Y. Minami, 2017 .

Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes

H. Harashima, K. Kajimoto, Y. Minami, 2014, FEBS open bio.

Resistin affects lipid metabolism during adipocyte maturation of 3T3‐L1 cells

K. Kogure, S. Hama, K. Kajimoto, 2013, The FEBS journal.

Resistin regulates the expression of plasminogen activator inhibitor-1 in 3T3-L1 adipocytes.

K. Kogure, S. Hama, K. Kajimoto, 2014, Biochemical and Biophysical Research Communications - BBRC.

Synchronized changes in transcript levels of genes activating cold exposure-induced thermogenesis in brown adipose tissue of experimental animals.

Y. Baba, Masahiro Watanabe, T. Tamaki, 2008, Biochimica et biophysica acta.

Essential role of citrate export from mitochondria at early differentiation stage of 3T3-L1 cells for their effective differentiation into fat cells, as revealed by studies using specific inhibitors of mitochondrial di- and tricarboxylate carriers.

Y. Shinohara, H. Terada, K. Kajimoto, 2005, Molecular genetics and metabolism.

PCR-select subtraction for characterization of messages differentially expressed in brown compared with white adipose tissue.

Y. Baba, N. Yamazaki, Y. Shinohara, 2003, Molecular genetics and metabolism.

Liver-Specific Silencing of Lipin1 Reduces Fat Mass as Well as Hepatic Triglyceride Biosynthesis in Mice.

H. Harashima, Yusuke Sato, K. Kajimoto, 2016, Biological & pharmaceutical bulletin.

Antiangiogenic nanotherapy for the control of obesity.

H. Harashima, K. Kajimoto, Md. Nazir Hossen, 2013, Nanomedicine.

"…the unexpected discovery that the targeted delivery of nanoparticles into obese adipose tissue could be passively enhanced via the enhanced permeability and retention effect may provide new opportunities to address and change the development of next-generation antiobesity drug formulations. "

K. Kajimoto, 2013 .

Vascular-targeted nanotherapy for obesity: unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery.

H. Harashima, H. Akita, K. Kajimoto, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Isolation and culture of microvascular endothelial cells from murine inguinal and epididymal adipose tissues.

H. Harashima, H. Akita, K. Kajimoto, 2010, Journal of immunological methods.

RNA interference-based silencing reveals the regulatory role of fatty acid-binding protein 4 in the production of IL-6 and vascular endothelial growth factor in 3T3-L1 adipocytes.

H. Harashima, H. Akita, K. Kajimoto, 2012, Endocrinology.

Noninvasive and persistent transfollicular drug delivery system using a combination of liposomes and iontophoresis.

K. Kanamura, K. Kogure, H. Harashima, 2011, International journal of pharmaceutics.

Cold-induced changes in gene expression in brown adipose tissue: implications for the activation of thermogenesis.

Masahiro Watanabe, C. Mori, Naoto Okada, 2008, Biological & pharmaceutical bulletin.

Identification of possible protein machinery involved in the thermogenic function of brown adipose tissue.

N. Yamazaki, Y. Shinohara, H. Terada, 2004, The journal of medical investigation : JMI.

Instructions for use Title Noninvasive and persistent transfollicular drug delivery systemusing a combination of liposomes and iontophoresis

K. Kanamura, K. Kogure, H. Harashima, 2017 .

A DNA microarray-based analysis of the host response to a nonviral gene carrier: a strategy for improving the immune response.

N. Kaji, Y. Baba, H. Harashima, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Electric Stimulus Opens Intercellular Spaces in Skin*

Y. Nagasaki, K. Kanamura, K. Kogure, 2013, The Journal of Biological Chemistry.

Expression profiles of three isoforms of inositol 1,4,5-trisphosphate receptor in brown adipose tissue of the rat.

N. Yamazaki, Y. Shinohara, H. Terada, 2003, Biochemical pharmacology.

Requirement of continuous transcription for the synthesis of sufficient amounts of protein by a cell-free rapid translation system.

Y. Baba, Y. Shinohara, H. Terada, 2002, Protein expression and purification.

Expression of NAD(+)-dependent isocitrate dehydrogenase in brown adipose tissue.

N. Yamazaki, Y. Shinohara, H. Terada, 2001, Biochemical and biophysical research communications.

Liposome Microencapsulation for the Surface Modification and Improved Entrapment of Cytochrome c for Targeted Delivery

Takashi Nakamura, H. Harashima, K. Kajimoto, 2018 .

Efficient intradermal delivery of superoxide dismutase using a combination of liposomes and iontophoresis for protection against UV-induced skin damage.

K. Kanamura, K. Kogure, H. Harashima, 2012, Biological & pharmaceutical bulletin.

Polymorphism of CYP11B2 Determines Salt Sensitivity in Japanese

N. Takashima, N. Iwai, H. Tomoike, 2007, Hypertension.

Assessment of genetic effects of polymorphisms in the MCP-1 gene on serum MCP-1 levels and myocardial infarction in Japanese.

Y. Kokubo, A. Okayama, H. Nonogi, 2006, Circulation journal : official journal of the Japanese Circulation Society.

Novel Expression of Equivocal Messages Containing Both Regions of Choline/Ethanolamine Kinase and Muscle Type Carnitine Palmitoyltransferase I*

N. Yamazaki, Y. Shinohara, H. Terada, 2000, The Journal of Biological Chemistry.

Quantitative comparison of adipocytokine gene expression during adipocyte maturation in non-obese and obese rats.

K. Kogure, S. Hama, K. Kajimoto, 2011, Biological & pharmaceutical bulletin.

Application of Micropore Device for Accurate, Easy, and Rapid Discrimination of Saccharomyces pastorianus from Dekkera spp.

M. Taniguchi, H. Abe, Kazumichi Yokota, 2021, Biosensors.

Comparative assessments of crucial factors for a functional ligand-targeted nanocarrier

H. Harashima, K. Kajimoto, M. Hyodo, 2014, Journal of drug targeting.

β-defensin 2 synthesized by a cell-free protein synthesis system and encapsulated in liposomes inhibits adhesion of Porphyromonas gingivalis to oral epithelial cells

Y. Hiroshima, M. Bando, K. Kajimoto, 2023, Odontology.

Nucleic acid purification from dried blood spot on FTA Elute Card provides template for polymerase chain reaction for highly sensitive Plasmodium detection.

M. Bando, Kazumichi Yokota, K. Kajimoto, 2019, Parasitology international.

Advances in an active and passive targeting to tumor and adipose tissues

Yu Sakurai, Hideyoshi Harashima, Hiroto Hatakeyama, 2015, Expert opinion on drug delivery.

Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy.

Takashi Nakamura, K. Kanamura, K. Kogure, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Quantitative Analysis of Serum Procollagen Type I C-Terminal Propeptide by Immunoassay on Microchip

Yasuo Shinohara, Yoshinobu Baba, Toshihiko Ooie, 2011, PloS one.

Accurate quantitation of salivary and pancreatic amylase activities in human plasma by microchip electrophoretic separation of the substrates and hydrolysates coupled with immunoinhibition

N. Kaji, M. Tokeshi, Y. Baba, 2008, Electrophoresis.

Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics.

Takashi Nakamura, H. Harashima, Yusuke Sato, 2017, Macromolecular bioscience.

MicroRNA and 3T3-L1 pre-adipocyte differentiation.

N. Iwai, K. Kajimoto, H. Naraba, 2006, RNA.

MicroRNA and 3 T 3L 1 pre-adipocyte differentiation

N. Iwai, K. Kajimoto, H. Naraba, 2006 .

Comparison between a multifunctional envelope-type nano device and lipoplex for delivery to the liver.

J. Yamauchi, H. Harashima, H. Akita, 2010, Biological & pharmaceutical bulletin.

Effect of Electrolyte Concentration on Cell Sensing by Measuring Ionic Current Waveform through Micropores

M. Taniguchi, M. Tsutsui, Kazumichi Yokota, 2021, Biosensors.

Loop-Mediated Isothermal Amplification in Microchambers on a Cell Microarray Chip for Identification of Plasmodium Species

Yusuke Ido, Kazumichi Yokota, K. Kajimoto, 2019, Journal of Parasitology.

The Monocyte Chemotactic Protein-1 Gene May Contribute to Hypertension in Dahl Salt-Sensitive Rats

N. Iwai, K. Kajimoto, T. Okuda, 2007, Hypertension Research.

Anti-angiogenic nanotherapy via active targeting systems to tumors and adipose tissue vasculature.

H. Harashima, K. Kajimoto, Y. Sakurai, 2015, Biomaterials science.

Lipocalin 2, synthesized using a cell-free protein synthesis system and encapsulated into liposomes, inhibits the adhesion of Porphyromonas gingivalis to human oral epithelial cells.

Y. Hiroshima, K. Kajimoto, M. Kataoka, 2022, Journal of periodontal research.

Development of an innovative drug delivery system targeted to adipose vessel utilizing novel nucleic acid aptamer for control of obesity

H. Harashima, K. Kajimoto, M. Hyodo, 2018 .

Instructions for use Title Hepatic Monoacylglycerol O-acyltransferase 1 as a PromisingTherapeutic Target for Steatosis , Obesity , and Type 2 Diabetes

N. Kaji, Y. Baba, H. Harashima, 2017 .

Hepatic Monoacylglycerol O-acyltransferase 1 as a Promising Therapeutic Target for Steatosis, Obesity, and Type 2 Diabetes

N. Kaji, Y. Baba, H. Harashima, 2014, Molecular therapy. Nucleic acids.

Transcytosis-Targeting Peptide: A Conductor of Liposomal Nanoparticles through the Endothelial Cell Barrier.

T. Fujiwara, Y. Tabata, H. Harashima, 2016, Small.

Instructions for use Title Application of apolipoprotein E-modified liposomal nanoparticles as a carrier for delivering DNA and nucleic acid in the brain

H. Harashima, Yusuke Sato, H. Akita, 2017 .

Differences in gene expression between noninvasive and invasive transitional cell carcinoma of the human bladder using complementary deoxyribonucleic acid microarray: preliminary results.

Y. Baba, Y. Shinohara, M. Ishikawa, 2006, Urologic oncology.

Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue.

H. Harashima, H. Akita, K. Kajimoto, 2010, Journal of controlled release : official journal of the Controlled Release Society.

DNA microarray analysis of whole blood cells and insulin-sensitive tissues reveals the usefulness of blood RNA profiling as a source of markers for predicting type 2 diabetes.

N. Kaji, Y. Baba, H. Harashima, 2010, Biological & pharmaceutical bulletin.

Gene expression profile in squamous cell carcinoma of the urinary bladder using complementary deoxyribonucleic acid microarray.

Y. Baba, Y. Shinohara, M. Ishikawa, 2007, Urologic oncology.

Extensive Genetic Analysis of 10 Candidate Genes for Hypertension in Japanese

Y. Kokubo, N. Iwai, H. Tomoike, 2006, Hypertension.

Development of a highly sensitive, quantitative, and rapid detection system for Plasmodium falciparum-infected red blood cells using a fluorescent blue-ray optical system.

N. Minakawa, Yusuke Ido, Y. Sofue, 2019, Biosensors & bioelectronics.

Comparison of gene expression profiles between white and brown adipose tissues of rat by microarray analysis.

A. Unami, Y. Baba, Y. Shinohara, 2004, Biochemical pharmacology.

Difference in intracellular temperature rise between matured and precursor brown adipocytes in response to uncoupler and β-adrenergic agonist stimuli

S. Uchiyama, Toshikazu Tsuji, H. Koizumi, 2017, Scientific Reports.

Multifunctional envelope-type nano device for controlled intracellular trafficking and selective targeting in vivo.

Takashi Nakamura, H. Harashima, Yusuke Sato, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Validation of the association between the gene encoding 5-lipoxygenase-activating protein and myocardial infarction in a Japanese population.

Y. Kokubo, H. Nonogi, N. Iwai, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Hydrophilic-treated plastic plates for wide-range analysis of Giemsa-stained red blood cells and automated Plasmodium infection rate counting

M. Bando, Yusuke Ido, K. Kajimoto, 2017, Malaria Journal.

Elimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion

H. Harashima, Saed Abbasi, K. Kajimoto, 2016, International journal of nanomedicine.

Exclusion of the Catechol-O-Methyltransferase Gene from Genes Contributing to Salt-Sensitive Hypertension in Dahl Salt-Sensitive Rats

N. Iwai, K. Kajimoto, Y. Hiura, 2007, Hypertension Research.

A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication.

Hideyoshi Harashima, Hidetaka Akita, H. Harashima, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Suppression of Lipid Accumulation in 3T3-L1 Adipocytes by α-Tocopheryl Succinate.

K. Kogure, T. Fukuta, K. Kajimoto, 2021, Biological & pharmaceutical bulletin.

Highly Sensitive and Rapid Quantitative Detection of Plasmodium falciparum Using an Image Cytometer

N. Minakawa, Kazumichi Yokota, K. Kajimoto, 2020, Microorganisms.