H. Tokuyama

发表

A Cell-Targeted Non-Cytotoxic Fluorescent Nanogel Thermometer Created with an Imidazolium-Containing Cationic Radical Initiator.

Masaru Kato, N. Inada, S. Uchiyama, 2018, Angewandte Chemie.

Fullerene–Oligonucleotide Conjugates: Photoinduced Sequence‐Specific DNA Cleavage

E. Nakamura, C. Hélène, H. Isobe, 1995 .

Photocytotoxicity of water-soluble fullerene derivatives.

H. Ohigashi, E. Nakamura, H. Tokuyama, 1996, Bioscience, biotechnology, and biochemistry.

Biological Activity of Water-Soluble Fullerenes. Structural Dependence of DNA Cleavage, Cytotoxicity, and Enzyme Inhibitory Activities Including HIV-Protease Inhibition

E. Nakamura, Y. Sugiura, H. Tokuyama, 1996 .

A Mild Copper-mediated Intramolecular Amination of Aryl Halides

H. Tokuyama, T. Fukuyama, Ken‐ichi Yamada, 2002 .

Total synthesis of (+)-yatakemycin.

K. Okano, H. Tokuyama, T. Fukuyama, 2006, Journal of the American Chemical Society.

A mild inter- and intramolecular amination of aryl halides with a combination of CuI and CsOAc

K. Okano, H. Tokuyama, T. Fukuyama, 2008 .

Synthesis of secondary arylamines through copper-mediated intermolecular aryl amination.

K. Okano, H. Tokuyama, T. Fukuyama, 2003, Organic letters.

Recent Progress on the Total Synthesis of Duocarmycins A and SA, Yatakemycin, and PDE-I and PDE-II

H. Tokuyama, Juri Sakata, 2019, Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules.

Double Functionalization of Styrenes by Cu-Mediated Assisted Tandem Catalysis

H. Tokuyama, Daichi Kawauchi, H. Ueda, 2019, European Journal of Organic Chemistry.

Total Synthesis of (+)-CC-1065 Utilizing Ring Expansion Reaction of Benzocyclobutenone Oxime Sulfonate.

K. Okano, H. Tokuyama, Juri Sakata, 2019, Organic letters.

A concise total synthesis of (−)-indolactam V

K. Okano, H. Tokuyama, Toshiharu Noji, 2015 .

Copper-mediated aromatic amination reaction and its application to the total synthesis of natural products.

K. Okano, H. Tokuyama, T. Fukuyama, 2014, Chemical communications.

Total synthesis of PDE-I and -II by copper-mediated double aryl amination

K. Okano, H. Tokuyama, Nakako Mitsuhashi, 2013 .

An Intramolecular Amination of Aryl Halides with a Combination of Copper (I) Iodide and Cesium Acetate: Preparation of 5,6‐Dimethoxyindole‐1,2‐Dicarboxylic Acid 1‐Benzyl Ester 2‐Methyl Ester

K. Okano, H. Tokuyama, T. Fukuyama, 2012 .

Total synthesis of dictyodendrins A-E.

K. Okano, H. Tokuyama, T. Fukuyama, 2011, Chemistry, an Asian journal.

Total Syntheses of Nitrogen-Containing Cyclic Natural Products Based on Aryl Amination

K. Okano, H. Tokuyama, T. Fukuyama, 2010 .

Total synthesis of PDE-II by copper-mediated double amination.

K. Okano, H. Tokuyama, Nakako Mitsuhashi, 2010, Chemical communications.

A Mild Copper-Mediated Intramolecular Amination of Aryl Halides.

H. Tokuyama, T. Fukuyama, Ken‐ichi Yamada, 2002 .

Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase

Junichi Takagi, Hirofumi Ueda, Emiko Mihara, 2016, Scientific Reports.

Acetic acid promoted metal-free aerobic carbon-carbon bond forming reactions at α-position of tertiary amines.

H. Tokuyama, H. Ueda, Kei Yoshida, 2014, Organic letters.

Synthetic studies on strictamine: unexpected oxidation of tertiary amine in Ru-catalyzed ring-closing olefin metathesis

H. Tokuyama, H. Ueda, Kei Yoshida, 2013 .

Estrogen receptor binding assay method for endocrine disruptors using fluorescence polarization.

Takeshi Fukushima, Kazuhiro Imai, Masako Maeda, 2002, Analytical chemistry.

Total syntheses of (−)-emestrin H and (−)-asteroxepin

H. Tokuyama, Juri Sakata, Kanato Umeki, 2020 .

Total synthesis of (-)-acetylaranotin.

K. Okano, H. Tokuyama, H. Fujiwara, 2012, Angewandte Chemie.

Synthetic Chemistry with Fullerenes. Photooxygenation of Olefins

E. Nakamura, H. Tokuyama, 1994 .

Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension: Novel Effects of an Old Drug.

R. Kurosawa, S. Miyata, H. Shimokawa, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Novel Potent ABCB1 Modulator, Phenethylisoquinoline Alkaloid, Reverses Multidrug Resistance in Cancer Cell.

M. Ishida, M. Unno, S. Ambudkar, 2018, Molecular pharmaceutics.

METHANO- AND PROPANOFULLERENES BY 1+2 AND 3+2 CYCLOADDITIONS OF VINYLCARBENE SPECIES

E. Nakamura, H. Isobe, H. Tokuyama, 1995 .

Synthetic and Computational Studies on Symmetry-Defined Double Cycloaddition of a New Tris-Annulating Reagent to C60

E. Nakamura, H. Isobe, H. Tokuyama, 1997 .

Total synthesis of (-)-strychnine.

H. Tokuyama, T. Fukuyama, Yosuke Kaburagi, 2004, Journal of the American Chemical Society.

Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo.

H. Nishina, J. Aoki, D. Saigusa, 2014, Journal of biochemistry.

A novel ketone synthesis by a palladium-catalyzed reaction of thiol esters and organozinc reagents

H. Tokuyama, T. Fukuyama, S. Yokoshima, 1998 .

Synthesis of oxo- and methylene-bridged C60 dimers, the first well-characterized species containing fullerene-fullerene bonds.

B. Chait, I. Haller, R. Strongin, 1995 .

Chemical derivatization of organofullerenes through oxidation, reduction, and carbon-oxygen and carbon-carbon bond-forming reactions

M. Prato, F. Wudl, E. Nakamura, 1993 .

Total Synthesis of (-)-Histrionicotoxin through a Stereoselective Radical Translocation-Cyclization Reaction.

K. Okano, H. Tokuyama, K. Takasu, 2017, Angewandte Chemie.

A Cell-Targeted Non-Cytotoxic Fluorescent Nanogel Thermometer Created with an Imidazolium-Containing Cationic Radical Initiator.

Masaru Kato, N. Inada, S. Uchiyama, 2018, Angewandte Chemie.

Cordybislactone, a stereoisomer of the 14-membered bislactone clonostachydiol, from the hopper pathogenic fungus Cordyceps sp. BCC 49294: revision of the absolute configuration of clonostachydiol

M. Isaka, H. Tokuyama, Arunrat Yangchum, 2018, The Journal of Antibiotics.

Construction of Tetrahydroquinolines with Spirocyclic Structures at the 4-Position

Takahiro Noro, H. Tokuyama, Juri Sakata, 2022, HETEROCYCLES.

Chemical Derivatization of Organofullerenes Through Oxidation, Reduction, and C‐O and C‐C Bond‐Forming Reactions.

M. Prato, F. Wudl, E. Nakamura, 1994 .

Nitrene additions to [60]fullerene do not generate [6,5] aziridines

H. Tokuyama, Amos B. Smith, 1996 .

Cyclopropenone-containing cysteine proteinase inhibitors. Synthesis and enzyme inhibitory activities.

K. Saito, E. Nakamura, M. Isaka, 1999, Bioorganic & medicinal chemistry.

Total Synthesis of (-)-Isoschizogamine.

H. Tokuyama, Kenji Sugimoto, H. Ueda, 2015, Chemistry.

Stereocontrolled total synthesis and biological evaluation of (−)- and (+)-petrosin and its derivatives

K. Okano, H. Tokuyama, K. Takasu, 2014 .

Stereocontrolled total synthesis of (−)-aspidophytine

H. Tokuyama, T. Fukuyama, Koji Matsumoto, 2003 .

SYNTHETIC STUDIES ON PASPALINE : LEWIS ACID-MEDIATED SEQUENTIAL CONSTRUCTION OF A-E RING SKELETON (Dedicated to Dr. Albert Padwa on his 75th birthday)

K. Okano, H. Tokuyama, Yu Yoshii, 2012 .

Catalytic imino Diels–Alder reaction by triflic imide and its application to one-pot synthesis from three components

H. Tokuyama, K. Takasu, M. Ihara, 2006 .

(2+2) cycloaddition reaction of alkyl enol ethers with acrylates by in situ generated silyl triflic imide catalyst.

H. Tokuyama, K. Takasu, M. Ihara, 2008, Chemical & pharmaceutical bulletin.

Total synthesis of dictyodendrin A and B.

K. Okano, H. Tokuyama, T. Fukuyama, 2010, Angewandte Chemie.

Fluorescence enhancement by hydroperoxides based on a change in the intramolecular charge transfer character of benzofurazan.

K. Nakagomi, T. Santa, K. Imai, 2005, Chemical communications.

A Concise Enantioselective Total Synthesis of (-)-Deoxoapodine.

H. Tokuyama, H. Ueda, Kosuke Okada, 2020, Angewandte Chemie.

Toward the total synthesis of (±)-andrastin C.

Rei Okamoto, H. Tokuyama, M. Ihara, 2013, The Journal of organic chemistry.

Efficient and Scalable Asymmetric Total Synthesis of (−)-Emetine with Pharmaceutical Grade Quality; First Multigram Scale Synthesis

H. Tokuyama, K. Satoh, M. Yamada, 2023, Organic Process Research & Development.

2-(2-AMINOPHENYL)-ACETALDEHYDE DIMETHYL ACETAL : A NOVEL REAGENT FOR THE PROTECTION OF CARBOXYLIC ACIDS

H. Tokuyama, T. Fukuyama, M. Linsell, 1998 .

Indole synthesis by radical cyclization of o-alkenylphenyl isocyanides and its application to the total synthesis of natural products.

H. Tokuyama, T. Fukuyama, 2002, Chemical record.

Autotandem catalysis: synthesis of pyrroles by gold-catalyzed cascade reaction.

H. Tokuyama, H. Kameya, Kenji Sugimoto, 2014, Organic letters.

Synthesis of a human urate transporter-1 inhibitor, an arginine vasopressin antagonist, and a 17β-hydroxysteroid dehydrogenase type-3 inhibitor, using ring-expansion of cyclic ketoximes with DIBALH.

K. Okano, H. Tokuyama, Hidetsura Cho, 2014, Chemical and pharmaceutical bulletin.

Radical Cyclization of 2-Alkenylthioanilides: A Novel Synthesis of 2,3-Disubstituted Indoles

H. Tokuyama, T. Fukuyama, Tohru Yamashita, 1999 .

Thermal Reactions of Substituted Cyclopropenone Acetals. Regio- and Stereochemistry of Vinylcarbene Formation and Low-Temperature (3 + 2) Cycloaddition.

E. Nakamura, M. Isaka, H. Tokuyama, 2010 .

Thermal reactions of substituted cyclopropenone acetals. Regio- and stereochemistry of vinylcarbene formation and low-temperature [3 + 2] cycloaddition

E. Nakamura, M. Isaka, H. Tokuyama, 1992 .

Synthesis of Acylsilanes by Palladium-catalyzed Cross-coupling Reaction of Thiol Esters and Silylzinc Chlorides

K. Okano, H. Tokuyama, Hiroki Azuma, 2011 .

Total synthesis of makaluvamine A/D, damirone B, batzelline C, makaluvone, and isobatzelline C featuring one-pot benzyne-mediated cyclization–functionalization

K. Okano, H. Tokuyama, T. Satoh, 2012 .

Auto-tandem catalysis in the synthesis of substituted quinolines from aldimines and electron-rich olefins: cascade Povarov-hydrogen-transfer reaction.

H. Tokuyama, K. Takasu, Y. Takemoto, 2008, The Journal of organic chemistry.

Convergent Synthesis of 2-Aryl-Substituted Quinolines by Gold-Catalyzed Cascade Reaction.

H. Tokuyama, H. Ueda, Minami Yamaguchi, 2016, Chemical & pharmaceutical bulletin.

Cascade and one-pot processes providing substituted quinolines from aldimines and allylsilanes: auto-tandem catalysis of triflic imide

H. Tokuyama, K. Takasu, Naoya Shindoh, 2007 .

Total Synthesis of Actinophyllic Acid.

H. Tokuyama, D. Y. Chen, Yu Yoshii, 2017, Angewandte Chemie.

Protecting-group-free total synthesis of (-)-rhazinilam and (-)-rhazinicine using a gold-catalyzed cascade cyclization.

Kenji Sugimoto, H. Tokuyama, H. Ueda, 2013, Angewandte Chemie.

Autotandem Catalysis: Synthesis of Pyrroles by Gold‐Catalyzed Cascade Reaction.

H. Tokuyama, H. Kameya, Kenji Sugimoto, 2015 .

Reduction of ethanethiol esters to aldehydes

H. Tokuyama, T. Fukuyama, Leping Li, 2002 .

Synthesis of Substituted Quinolizidines via a Gold-Catalyzed Double Cyclization Cascade

H. Tokuyama, Kenji Sugimoto, H. Ueda, 2016 .

Synthetic studies toward penitrem E: enantiocontrolled construction of B-E rings.

K. Okano, H. Tokuyama, K. Takasu, 2015, Chemical communications.

Facile isomerization of silyl enol ethers catalyzed by triflic imide and its application to one-pot isomerization–(2 + 2) cycloaddition

H. Tokuyama, K. Takasu, Y. Takemoto, 2012, Beilstein journal of organic chemistry.

Synthesis of Cyclopropenone-Containing Amino Acid Mimic. Addition of Cyclopropenyl Cerium Reagent to α-Amino Aldehydes

E. Nakamura, M. Isaka, H. Tokuyama, 1995 .

Stereocontrolled total synthesis of (+)-vinblastine.

T. Ueda, H. Tokuyama, T. Fukuyama, 2002, Journal of the American Chemical Society.

Facile construction of N-hydroxybenzazocine: enantioselective total synthesis of (+)-FR900482.

Masashi Suzuki, H. Tokuyama, T. Fukuyama, 2002, Angewandte Chemie.

PALLADIUM-CATALYZED COUPLING OF N-HETEROARYL SULFIDES WITH ORGANOZINC REAGENTS

T. Miyazaki, H. Tokuyama, T. Fukuyama, 2009 .

[Development of new synthetic methods and their application to synthesis of useful compounds].

H. Tokuyama, 2003, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Facile Palladium-Mediated Conversion of Ethanethiol Esters to Aldehydes and Ketones

H. Tokuyama, T. Fukuyama, S. Yokoshima, 1998 .

New Odorless Protocols for the Synthesis of Aldehydes and Ketones from Thiol Esters

T. Miyazaki, H. Tokuyama, T. Fukuyama, 2004 .

Synthetic Studies toward HaouamineB: Construction of Indenotetrahydropyridone Skeleton

K. Okano, H. Tokuyama, Kenji Sugimoto, 2011 .

Total synthesis of (-)-haouamine B pentaacetate and structural revision of haouamine B.

K. Okano, H. Tokuyama, Kenji Sugimoto, 2014, Angewandte Chemie.

Total synthesis of tryprostatins A and B

H. Tokuyama, T. Fukuyama, T. Yamakawa, 2011 .

Synthesis of substituted anilines via a gold-catalyzed three-component reaction.

H. Tokuyama, H. Ueda, Minami Yamaguchi, 2020, Organic & biomolecular chemistry.

Total syntheses of codonopsinine and 4-epi-codonopsinine via gold-mediated tandem-catalyzed pyrrole synthesis

H. Tokuyama, H. Ueda, Minami Yamaguchi, 2016, The Journal of Antibiotics.

Rapid Assembly of Protoilludane Skeleton through Tandem Catalysis: Total Synthesis of Paesslerin A and Its Structural Revision.

H. Tokuyama, K. Takasu, M. Ihara, 2019, Organic letters.

An Obtuse-angled Corner Unit for Fluctuating Carbon Nanohoops.

H. Isobe, H. Tokuyama, Sota Sato, 2017, Chemistry, an Asian journal.

Total synthesis of the duocarmycins.

H. Tokuyama, T. Fukuyama, Ken‐ichi Yamada, 2003, Journal of the American Chemical Society.

Divergent total synthesis of (−)-aspidophytine and its congeners via Fischer indole synthesis

H. Tokuyama, H. Ueda, H. Satoh, 2013 .

Total synthesis of (+)-haplophytine.

H. Tokuyama, T. Fukuyama, Kenji Sugimoto, 2009, Angewandte Chemie.

Synthetic Studies on Haplophytine: Protective-Group-Controlled Rearrangement

H. Tokuyama, T. Fukuyama, Koji Matsumoto, 2007 .

Enantioselective total synthesis of aspidophytine.

H. Tokuyama, T. Fukuyama, Koji Matsumoto, 2003, Organic letters.

Design and synthesis of thiazoline-thiazole hybrid macrocycles possessing strong binding affinity to Pb2+ and Cd2+.

H. Tokuyama, T. Fukuyama, Fu‐She Han, 2007, Chemical communications.

Stereocontrolled total synthesis of (-)-kainic acid.

H. Sakaguchi, H. Tokuyama, T. Fukuyama, 2007, Organic letters.

Synthesis and biological activities of cyclopropenone antibiotic penitricin and congeners.

E. Nakamura, M. Isaka, H. Tokuyama, 1992, The Journal of antibiotics.

Stereocontrolled total synthesis of (-)-eudistomin C.

H. Tokuyama, T. Fukuyama, Tohru Yamashita, 2005, Journal of the American Chemical Society.

Acceleration of Reaction by Microwave Irradiation

H. Tokuyama, Masaharu Nakamura, 2005 .

Total synthesis of batzelline C and isobatzelline C

K. Okano, H. Tokuyama, T. Satoh, 2012 .

Synthetic studies on discorhabdin V: Construction of the A–F hexacyclic framework

Takahiro Noro, H. Tokuyama, Juri Sakata, 2021, Tetrahedron Letters.

Stereocontrolled total synthesis of (-)-kainic acid. Regio- and stereoselective lithiation of pyrrolidine ring with the (+)-sparteine surrogate.

H. Tokuyama, T. Fukuyama, Y. Morita, 2005, Organic letters.

Synthetic studies on isoschizogamine: construction of [3.3.1] bicyclic aminal core by using oxidative skeletal rearrangement

H. Tokuyama, H. Ueda, A. Takada, 2013 .

Formation of Xanthone Oxime and Related Compounds Using a Combination of tert-Butyl Nitrite and Potassium Hexamethyldisilazide

K. Okano, Takahiro Noro, H. Tokuyama, 2014 .

Catalytic Enantioselective 5-Endo-Bromocycloetherification of Unactivated Cyclic Alkenes

H. Tokuyama, H. Ueda, Kei Yoshida, 2022, SSRN Electronic Journal.

Condensation of Carboxylic Acids with Non-Nucleophilic N-Heterocycles and Anilides Using Boc2O.

H. Tokuyama, H. Ueda, Atsushi Umehara, 2016, The Journal of organic chemistry.

A Concise Enantioselective Total Synthesis of (−)‐Deoxoapodine

H. Tokuyama, H. Ueda, Kei Yoshida, 2020, Angewandte Chemie.

Structural Determination of (-)-SCH 64874 and Hirsutellomycin by Semisynthesis.

M. Isaka, K. Okano, H. Tokuyama, 2017, The Journal of organic chemistry.

Preparation of Horner‐Wadsworth‐Emmons Reagent: Methyl 2‐Benzyloxycarbonylamino‐2‐(Dimethoxy‐ Phosphinyl)Acetate

K. Okano, H. Tokuyama, T. Fukuyama, 2012 .

A novel indole synthesis via conjugate addition of pyrrolidine to o-nitrophenylacetylenes

H. Tokuyama, T. Fukuyama, Y. Han-ya, 2007 .

A Novel Protocol for Construction of Indolylmethyl Group at Aldehydes or Ketones

H. Tokuyama, T. Fukuyama, G. Peng, 2001 .

AgNTf2-Mediated Arylation of Bromopyrroloindolines

H. Tokuyama, Daichi Kawauchi, H. Ueda, 2017 .

Total Synthesis of (+)-MPC1001B.

K. Okano, H. Tokuyama, H. Fujiwara, 2016, Angewandte Chemie.

Stereocontrolled total synthesis of (+)-vinblastine

H. Tokuyama, T. Fukuyama, S. Yokoshima, 2003 .

Total synthesis of (+)-yatakemycin.

K. Okano, H. Tokuyama, T. Fukuyama, 2008, Chemistry, an Asian journal.

Radical Cyclization of 2-Alkenylthioanilides. A Novel Synthesis of 2,3-Disubstituted Indoles.

H. Tokuyama, T. Fukuyama, Tohru Yamashita, 2010 .

Total synthesis of (+)‐vinblastine: Control of the stereochemistry at C18′

H. Tokuyama, T. Fukuyama, S. Yokoshima, 2010 .

Total synthesis of (-)-conophylline and (-)-conophyllidine.

H. Tokuyama, T. Fukuyama, Y. Han-ya, 2011, Angewandte Chemie.

Synthetic studies on lycopodine: construction of hexahydrojulolidine core by intramolecular Mannich reaction

H. Tokuyama, H. Ueda, Takanao Sato, 2014 .

Thermal and palladium-catalyzed [3 + 2] synthesis of cyclopentadienone acetals from cyclopropenone acetals and acetylenes.

Takatsugu Tanaka, E. Nakamura, H. Isobe, 2004, Organic letters.

Nitrile Synthesis by Aerobic Oxidation of Primary Amines and in situ Generated Imines from Aldehydes and Ammonium Salt with Grubbs Catalyst

H. Tokuyama, Daichi Kawauchi, H. Ueda, 2020 .

Regiospecific rearrangement of hydroxylamines to secondary amines using diisobutylaluminum hydride

K. Okano, H. Tokuyama, Kenji Sugimoto, 2010 .

Divergent Total Syntheses of Isobatzellines A/B and Batzelline A.

H. Tokuyama, Juri Sakata, Yumi Yamashita, 2020, Organic letters.

Enantioselective Total Synthesis of (+)-Gelsemine: Determination of Its Absolute Configuration

H. Tokuyama, T. Fukuyama, S. Yokoshima, 2000 .

Regiospecific synthesis of unsubstituted basic skeletons of heterocycles containing nitrogen neighboring an aromatic ring by the reductive ring expansion reaction using diisobutylaluminum hydride

E. Kwon, H. Tokuyama, Kenji Sugimoto, 2009 .

Synthesis of substituted indoline and carbazole by benzyne-mediated cyclization-functionalization.

K. Okano, H. Tokuyama, Toshiharu Noji, 2013, Organic letters.

Bioinspired Total Synthesis of the Dimeric Indole Alkaloid (+)-Haplophytine by Direct Coupling and Late-Stage Oxidative Rearrangement.

H. Tokuyama, H. Ueda, Ken-ichi Ojima, 2016, Angewandte Chemie.

Conversion of Vindoline into 11-Mesyloxytabersonine.

H. Tokuyama, T. Fukuyama, S. Yokoshima, 2016, Chemical & pharmaceutical bulletin.

Total synthesis of (−)-rhazinilam using 1,3-dipolar cycloaddition of optically active münchnone intermediate

H. Tokuyama, Kenji Sugimoto, Y. Miyakawa, 2015 .

Novel structural motifs consisting of chiral thiazolines: synthesis, molecular recognition, and anticancer activity.

H. Tokuyama, M. Cheung, T. Fukuyama, 2007, Chemistry.

Synthesis of chiral cyclic oligothiazolines: a novel structural motif for a macrocyclic molecule.

H. Tokuyama, M. Cheung, T. Fukuyama, 2006, Chemical Communications.

Photoinduced biochemical activity of fullerene carboxylic acid

Eiichi Nakamura, Yukio Sugiura, E. Nakamura, 1993 .

Regio- and diastereo-controlled double cycloaddition to [60] fullerene: one-step synthesis of Cs and C2 chiral organofullerenes with new tris-annulating reagents

E. Nakamura, H. Isobe, H. Tokuyama, 1996 .

First fluorescent photoinduced electron transfer (PET) reagent for hydroperoxides.

T. Santa, K. Imai, S. Uchiyama, 2003, Organic letters.

Construction of Indole Structure on Pyrroloindolines via AgNTf2-Mediated Amination/Cyclization Cascade: Application to Total Synthesis of (+)-Pestalazine B.

H. Tokuyama, H. Ueda, Hiroyuki Hakamata, 2019, Organic letters.

Synthesis of Lysergic Acid Methyl Ester via the Double Cyclization Strategy

H. Tokuyama, T. Fukuyama, M. Isomura, 2009 .

AgNTf2-Mediated Allylation with Allylsilanes at C3a-Position of Hexahydropyrroloindoles: Application to Total Syntheses of Amauromine Alkaloids.

H. Tokuyama, H. Ueda, Soichiro Sato, 2017, Organic letters.

Aerobic Dehydrogenation of N-Heterocycles with Grubbs Catalyst: Its Application to Assisted-Tandem Catalysis to Construct N-Containing Fused Heteroarenes.

H. Tokuyama, Daichi Kawauchi, H. Ueda, 2020, Chemistry.

Total Synthesis of (-)-Lepadiformine A via Radical Translocation-Cyclization Reaction.

H. Tokuyama, Juri Sakata, Manabu Sato, 2010, Organic letters.

Total Synthesis of (±)-LepadiformineA via Radical Translocation-Cyclization Reaction

K. Okano, H. Tokuyama, K. Takasu, 2010 .

Synthesis of 2,3-Dialkylindoles from 2-Alkenylphenylisocyanides and Imines by Silyltelluride- and Tin Hydride-Mediated Sequential Radical Reactions

H. Tokuyama, S. Yamago, T. Fukuyama, 2005 .

[1 + 2] and [3 + 2] cycloaddition reactions of vinylcarbenes with C60

E. Nakamura, H. Tokuyama, Masaharu Nakamura, 1993 .

Regioselective generation and stereoselective [1+2] cycloaddition of substituted vinylcarbenes

E. Nakamura, H. Tokuyama, Taro Yamada, 1993 .

Synthesis of 2,3-disubstituted indoles by radical cyclization with hypophosphorous acid and its application to total synthesis of (′)-catharanthine

H. Tokuyama, T. Fukuyama, Yosuke Kaburagi, 2002 .

Protection of Diols with 4‐(tert‐Butyldimethylsilyloxy)Benzylidene Acetal and its Deprotection: (4‐((4R,5R)‐4,5‐Diphenyl‐1,3‐Dioxolan‐2‐Yl)Phenoxy)(Tert‐ Butyl)Dimethylsilane

K. Okano, H. Tokuyama, T. Fukuyama, 2009 .

Transformation of primary amines to N-monoalkylhydroxylamines: N-hydroxy-(S)-1-phenylethylamine oxalate: [(Benzenemethanamine, N-hydroxy--methyl-, (S)-, ethanedioate)]

S. Denmark, H. Tokuyama, T. Fukuyama, 2003 .

A Novel Transformation of Primary Amines to N-Monoalkylhydroxylamines

H. Tokuyama, T. Fukuyama, A. Amano, 2000 .

Enantiocontrolled total synthesis of (-)-mersicarpine.

K. Okano, H. Tokuyama, Kenji Sugimoto, 2013, Chemistry.

Concise total synthesis of (-)-mersicarpine.

K. Okano, H. Tokuyama, Kenji Sugimoto, 2012, Organic letters.

Synthesis of (+)-vinblastine and its analogues.

T. Miyazaki, H. Osada, H. Tokuyama, 2007, Organic letters.

Stereocontrolled total synthesis of (+)-vincristine.

H. Tokuyama, T. Fukuyama, S. Yokoshima, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Total Syntheses of (+)‐T988 B and (+)‐T988 C through the AgNTf2‐Mediated Coupling of Bromopyrroloindoline with Indole

H. Tokuyama, H. Ueda, Soichiro Sato, 2017 .

A new class of proteinase inhibitor. Cyclopropenone-containing inhibitor of papain

E. Nakamura, M. Isaka, H. Tokuyama, 1993 .

Stereocontrolled Total Synthesis of (+)‐Vinblastine.

T. Ueda, H. Tokuyama, T. Fukuyama, 2002 .

A Practical Route to Quinolines from Anilines

T. Ueda, H. Tokuyama, T. Fukuyama, 2001 .

Total syntheses of leuconoxine, leuconodine B, and melodinine E by oxidative cyclic aminal formation and diastereoselective ring-closing metathesis.

H. Tokuyama, H. Ueda, Atsushi Umehara, 2014, Organic letters.

Ring-Expansion Reaction of Oximes with Aluminum Reductants

K. Okano, H. Tokuyama, Kenji Sugimoto, 2012, Molecules.

Regioselective synthesis of heterocycles containing nitrogen neighboring an aromatic ring by reductive ring expansion using diisobutylaluminum hydride and studies on the reaction mechanism.

H. Tokuyama, Kenji Sugimoto, Hidetsura Cho, 2010, The Journal of organic chemistry.

A New Class of Proteinase Inhibitor. Cyclopropenone‐Containing Inhibitor of Papain.

E. Nakamura, M. Isaka, H. Tokuyama, 1993 .

Intramolecular 1,3-dipolar cycloaddition strategy for enantioselective synthesis of FR-900482 analogues.

M. Suzuki, H. Tokuyama, T. Fukuyama, 2001, Organic letters.

Fluorescent Labeling Method Re-Evaluates the Intriguing Thermoresponsive Behavior of Poly(acrylamide-co-acrylonitrile)s with Upper Critical Solution Temperatures

K. Okabe, S. Uchiyama, H. Tokuyama, 2019, Macromolecules.

Stereocontrolled Total Synthesis of (-)-Aspidophytine.

H. Tokuyama, T. Fukuyama, Koji Matsumoto, 2004 .

Synthesis of 2,3-Disubstituted Indoles by Palladium-Mediated Coupling of 2-Iodoindoles

H. Tokuyama, T. Fukuyama, Xiaoqi Chen, 2000 .

New Odorless Protocols for the Synthesis of Aldehydes and Ketones from Thiol Esters.

T. Miyazaki, H. Tokuyama, T. Fukuyama, 2004 .

Palladium-Mediated Synthesis of Aldehydes and Ketones from Thiol Esters

H. Tokuyama, T. Fukuyama, 2005 .

Selective accumulation of rhodacyanine in plasmodial mitochondria is related to the growth inhibition of malaria parasites

S. Kuge, A. Naganuma, Hye-Sook Kim, 2010 .

Synthesis and biological evaluation of optically active Ki16425.

J. Aoki, A. Inoue, H. Tokuyama, 2012, Bioorganic & medicinal chemistry letters.

Mild Debenzylation of Aryl Benzyl Ether with BCl3 in the Presence of Pentamethylbenzene as a Non‐Lewis‐Basic Cation Scavenger.

K. Okano, H. Tokuyama, T. Fukuyama, 2008 .

Photoredox-catalyzed intramolecular cyclopropanation of alkenes with α-bromo-β-keto esters.

H. Tokuyama, Miyu Furuta, K. Ide, 2021, Organic & biomolecular chemistry.

ONE-POT CLAISEN REARRANGEMENT WITH N-BUTYL VINYL ETHER

T. Ueda, H. Tokuyama, T. Fukuyama, 2002 .

4-(tert-Butyldimethylsilyloxy)benzylidene acetal: a novel benzylidene-type protecting group for 1,2-diols

H. Tokuyama, T. Fukuyama, K. Shimada, 2004 .

Synthetic Studies on Plakinidines

K. Okano, H. Tokuyama, Juri Sakata, 2019, Heterocycles.

In vivo biological behavior of a water-miscible fullerene: 14C labeling, absorption, distribution, excretion and acute toxicity.

E. Nakamura, K. Kikuchi, H. Tokuyama, 1995, Chemistry & biology.

Enantioselective total synthesis of FR900482.

Masashi Suzuki, H. Tokuyama, T. Fukuyama, 2004, The Journal of organic chemistry.

Trichloroboron-promoted Deprotection of Phenolic Benzyl Ether Using Pentamethylbenzene as a Non Lewis-Basic Cation Scavenger

K. Okano, H. Tokuyama, S. Okaya, 2016 .

Synthesis of vinyloxazolidinones by palladium-catalyzed CO2-recycling reaction of 4-(benzylamino)-2-butenyl carbonates

H. Tokuyama, M. Ihara, Masahiro Yoshida, 2007 .

Mild Debenzylation of ArylBenzyl Ether with BCl3 in the Presence of Pentamethylbenzeneas a Non-Lewis-Basic Cation Scavenger

K. Okano, H. Tokuyama, T. Fukuyama, 2008 .

Synthesis of 2,3-Disubstituted Indoles by Palladium-Mediated Coupling of 2-Iodoindoles

H. Tokuyama, T. Fukuyama, Xiaoqi Chen, 2000 .

Photoaddition of silyl ketene acetal to [60]fullerene. Synthesis of α-fullerene-substituted carboxylic esters

E. Nakamura, H. Isobe, H. Tokuyama, 1994 .

Synthetic studies toward penitrem E: enantiocontrolled construction of B-E rings.

K. Okano, H. Tokuyama, K. Takasu, 2015, Chemical communications.

Total synthesis of (-)-conophylline and (-)-conophyllidine.

H. Tokuyama, T. Fukuyama, Y. Han-ya, 2011, Angewandte Chemie.

Total Synthesis of (-)-Isoschizogamine.

H. Tokuyama, Kenji Sugimoto, H. Ueda, 2015, Chemistry.

Synthesis of eudistomin C and E: improved preparation of the indole unit.

T. Miyazaki, H. Tokuyama, T. Fukuyama, 2008, Organic letters.

Concise Total Synthesis of (+)-Pleiocarpamine and Convergent Total Syntheses of (+)-Voacalgine A and (+)-Bipleiophylline via an Aerobic Oxidative Coupling.

H. Tokuyama, H. Ueda, Ken-ichi Ojima, 2023, Journal of the American Chemical Society.