A. Rapraeger

发表

The appearance of an extracellular arylsulfatase during morphogenesis of the sea urchin Strongylocentrotus purpuratus.

D. Epel, A. Rapraeger, 1981, Developmental biology.

Alan C. Rapraeger, A. Rapraeger, 2000, The Journal of cell biology.

Syndecan-1 signals independently of beta1 integrins during Raji cell spreading.

A. Rapraeger, C. Lebakken, K. J. McQuade, 2000, Experimental cell research.

The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans.

M. Jalkanen, M. Bernfield, A. Rapraeger, 1985, The Journal of biological chemistry.

Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation

A. Rapraeger, DeannaLee M. Beauvais, 2010, Journal of Cell Science.

Mouse mammary epithelial cells produce basement membrane and cell surface heparan sulfate proteoglycans containing distinct core proteins

M. Jalkanen, M. Bernfield, A. Rapraeger, 1988, The Journal of cell biology.

Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly

B. L. Allen, A. Rapraeger, 2003, The Journal of cell biology.

Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells

M. Jalkanen, M. Bernfield, A. Rapraeger, 1986, The Journal of cell biology.

Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration.

H. Rauvala, B. Olwin, A. Rapraeger, 2004, Genes & development.

Cell-surface Heparan Sulfate Proteoglycans Potentiate Chordin Antagonism of Bone Morphogenetic Protein Signaling and Are Necessary for Cellular Uptake of Chordin*

W. N. Pappano, B. L. Allen, D. Greenspan, 2004, Journal of Biological Chemistry.

Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression

S. Nelson, A. Rapraeger, DeannaLee M. Beauvais, 2022, The Journal of biological chemistry.

Sdc 1-coupled IGF 1 R promotes myeloma survival 1 Syndecan-1 ( CD 138 ) activates IGF 1 R and suppresses apoptosis in multiple myeloma : blockade by synstatinIGF 1 R inhibits tumor growth in vivo

R. Sanderson, A. Rapraeger, Yang Yang, 2016 .

Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth.

R. Sanderson, A. Rapraeger, Yang Yang, 2016, Cancer research.

Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications.

Xiaojun Tan, P. Lambert, Richard A. Anderson, 2016, Trends in cell biology.

Differential ability of heparan sulfate proteoglycans to assemble the fibroblast growth factor receptor complex in situ

A. Friedl, A. Rapraeger, Z. Chang, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition

M. Filla, B. L. Allen, A. Rapraeger, 2001, The Journal of cell biology.

Post-transcriptional regulation of syndecan-1 expression by cAMP in peritoneal macrophages

C. Yeaman, A. Rapraeger, Charles Yeaman, 1993, The Journal of cell biology.

Differential binding of fibroblast growth factor-2 and -7 to basement membrane heparan sulfate: comparison of normal and abnormal human tissues.

A. Friedl, A. Rapraeger, Z. Chang, 1997, The American journal of pathology.

The syndecan-1 ectodomain regulates αvβ3 integrin activity in human mammary carcinoma cells

A. Rapraeger, B. Burbach, DeannaLee M. Beauvais, 2004, The Journal of cell biology.

A polymer scaffold for protein oligomerization.

L. Kiessling, B. L. Allen, Byron R. Griffith, 2004, Journal of the American Chemical Society.

Heparan sulfate-mediated binding of epithelial cell surface proteoglycan to thrombospondin.

D. Mosher, A. Rapraeger, D. Mosher, 1989, The Journal of biological chemistry.

Heparan sulfate proteoglycans from mouse mammary epithelial cells. Cell surface proteoglycan as a receptor for interstitial collagens.

M. Bernfield, A. Rapraeger, J. Koda, 1985, The Journal of biological chemistry.

Heparanase-induced shedding of syndecan-1/CD138 in myeloma and endothelial cells activates VEGFR2 and an invasive phenotype: prevention by novel synstatins

A. Purushothaman, R. Sanderson, A. Rapraeger, 2016, Oncogenesis.

Elevated levels of syndecan-1 expression confer potent serum-dependent growth in human 293T cells.

V. Dixit, K. O'rourke, J. Varani, 1995, Cancer research.

Heparan sulfate-growth factor interactions.

A. Rapraeger, 2002, Methods in cell biology.

The cell surface proteoglycan syndecan‐1 mediates fibroblast growth factor‐2 binding and activity

M. Filla, A. Rapraeger, Phoungan Dam, 1998, Journal of cellular physiology.

[11] Regulation by heparan sulfate in fibroblast growth factor signaling

B. Olwin, S. Guimond, A. Rapraeger, 1994 .

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.

A. Purushothaman, R. Sanderson, T. Uyama, 2010, Blood.

Heparan sulfate proteoglycan and FGF receptor target basic FGF to different intracellular destinations.

A. Rapraeger, J. Reiland, Jane Reiland, 1993, Journal of cell science.

13 – Proteoglycans of Plasma Membranes: Multiple Functions in Cell Surface Biology

A. Rapraeger, 1993 .

Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy

R. Sanderson, A. Rapraeger, I. Vlodavsky, 2017, The FEBS journal.

The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif

Suyong Choi, P. Lambert, Mo Chen, 2019, Scientific Reports.

Syndecan-1 regulates αvβ3 and αvβ5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor

Brian J. Ell, A. Rapraeger, A. McWhorter, 2009, The Journal of experimental medicine.

Syndecan-1 regulates αvβ5 integrin activity in B82L fibroblasts

A. Rapraeger, K. J. McQuade, B. Burbach, 2006, Journal of Cell Science.

Syndecan-1 regulates (cid:2) v (cid:3) 3 and (cid:2) v (cid:3) 5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor

Brian J. Ell, A. Rapraeger, A. McWhorter, 2009 .

The Specificity of IQGAP1 Toward the PI3K-Akt Pathway is Dependent on the IQ3 motif

Suyong Choi, P. Lambert, Mo Chen, 2018, bioRxiv.

Interaction of the cell surface with the extracellular matrix during epithelial morphogenesis

M. Bernfield, A. Rapraeger, J. Koda, 1983 .

Integral Membrane Proteoglycans as Matrix Receptors: Role in Cytoskeleton and Matrix Assembly at the Epithelial Cell Surface

A. Rapraeger, 1987 .

Characterization of the High Affinity Cell-binding Domain in the Cell Surface Proteoglycan Syndecan-4*

A. Rapraeger, A. McFall, 1998, The Journal of Biological Chemistry.

Two hierarchies of FGF-2 signaling in heparin: mitogenic stimulation and high-affinity binding/receptor transphosphorylation.

S. Guimond, A. Rapraeger, A. Krufka, 1996, Biochemistry.

Identification of an Adhesion Site within the Syndecan-4 Extracellular Protein Domain*

A. Rapraeger, A. McFall, Aidan J. McFall, 1997, The Journal of Biological Chemistry.

Cell surface proteoglycan of mouse mammary epithelial cells is shed by cleavage of its matrix-binding ectodomain from its membrane-associated domain

M. Jalkanen, M. Bernfield, A. Rapraeger, 1987, The Journal of cell biology.

Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody

M. Jalkanen, M. Bernfield, A. Rapraeger, 1985, The Journal of cell biology.

Cell surface proteoglycan of mammary epithelial cells. Protease releases a heparan sulfate-rich ectodomain from a putative membrane-anchored domain.

M. Bernfield, A. Rapraeger, 1985, The Journal of biological chemistry.

Interaction of syndecan and alpha6beta4 integrin cytoplasmic domains: regulation of ErbB2-mediated integrin activation.

A. Rapraeger, Haiyao Wang, L. Leavitt, 2010, The Journal of biological chemistry.

Role of FGFs in skeletal muscle and limb development

B. Riley, B. Olwin, M. E. Zuber, 1994, Molecular reproduction and development.

The coordinated regulation of heparan sulfate, syndecans and cell behavior.

A. Rapraeger, 1993, Current opinion in cell biology.

AN INTEGRAL MEMBRANE PROTEOGLYCAN IS CAPABLE OF BINDING COMPONENTS OF THE CYTOSKELETON AND THE EXTRACELLULAR MATRIX1

M. Bernfield, A. Rapraeger, 1982 .

Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1.

C. Yeaman, A. Rapraeger, J. Reiland, 1996, The Biochemical journal.

Ponatinib sensitizes myeloma cells to MEK inhibition in the high-risk VQ model

N. Callander, M. Suresh, A. Rapraeger, 2022, Scientific Reports.

Syndecan-1-mediated cell spreading requires signaling by αvβ3 integrins in human breast carcinoma cells

A. Rapraeger, DeannaLee M. Beauvais, 2003 .

Syndecan: Regulator of Cell Morphology and Growth Factor Action at the Cell-matrix Interface.

M. Jalkanen, A. Rapraeger, K. Elenius, 1993 .

Remodelling of the basement membrane: morphogenesis and maturation.

M. Bernfield, A. Rapraeger, J. Koda, 1984, Ciba Foundation symposium.

Regulation by heparan sulfate in fibroblast growth factor signaling.

B. Olwin, S. Guimond, A. Rapraeger, 1994, Methods in enzymology.

Syndecan-1 and Syndecan-4 Capture Epidermal Growth Factor Receptor Family Members and the α3β1 Integrin Via Binding Sites in Their Ectodomains

Haining Jin, A. Rapraeger, Haiyao Wang, 2015, The Journal of Biological Chemistry.

Heparan sulfate proteoglycans from mouse mammary epithelial cells. A putative membrane proteoglycan associates quantitatively with lipid vesicles.

M. Bernfield, A. Rapraeger, 1983, The Journal of biological chemistry.

Altered structure of the hybrid cell surface proteoglycan of mammary epithelial cells in response to transforming growth factor-beta

A. Rapraeger, S. Rasmussen, S. Rasmussen, 1988, The Journal of cell biology.

Tissue-specific binding by FGF and FGF receptors to endogenous heparan sulfates.

A. Friedl, M. Filla, A. Rapraeger, 2001, Methods in molecular biology.

Syndecans in tumor cell adhesion and signaling

A. Rapraeger, DeannaLee M. Beauvais, 2004, Reproductive biology and endocrinology : RB&E.

Regulation of Fibroblast Growth Factor-2 Activity by Human Ovarian Cancer Tumor Endothelium

G. Jayson, A. Friedl, A. Rapraeger, 2005, Clinical Cancer Research.

A quantitative solid-phase assay for identifying radiolabeled glycosaminoglycans in crude cell extracts.

C. Yeaman, A. Rapraeger, Charles Yeaman, 1989, Analytical biochemistry.

Syndecan-1 ectodomain regulates matrix-dependent signaling in human breast carcinoma cells.

A. Rapraeger, Yan Ji, B. Burbach, 2004, Experimental cell research.

The Hidden Conundrum of Phosphoinositide Signaling in Cancer.

Suyong Choi, Xiaojun Tan, P. Lambert, 2016, Trends in cancer.

Molecular interactions of the syndecan core proteins.

A. Rapraeger, V. Ott, Vanessa L. Ott, 1998, Current opinion in cell biology.

Syndecan-1 accumulates in lysosomes of poorly differentiated breast carcinoma cells.

Andreas Friedl, A. Friedl, C. Mundhenke, 2003, Matrix biology : journal of the International Society for Matrix Biology.

HSulf-1 and HSulf-2 Are Potent Inhibitors of Myeloma Tumor Growth in Vivo*

R. Sanderson, Z. Shriver, R. Sasisekharan, 2005, Journal of Biological Chemistry.

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

B. Olwin, S. Guimond, A. Rapraeger, 1993, The Journal of biological chemistry.

Syndecan-1 Transmembrane and Extracellular Domains Have Unique and Distinct Roles in Cell Spreading*

A. Rapraeger, K. J. McQuade, K. J. Mcquade, 2003, Journal of Biological Chemistry.

Fibroblast growth factor receptor‐1 mediates the inhibition of endothelial cell proliferation and the promotion of skeletal myoblast differentiation by SPARC: A role for protein kinase A

E. Sage, B. L. Allen, A. Rapraeger, 2003, Journal of cellular biochemistry.

Tyrosine Phosphorylation of Syndecan-1 and -4 Cytoplasmic Domains in Adherent B82 Fibroblasts*

A. Rapraeger, A C Rapraeger, V L Ott, 1998, The Journal of Biological Chemistry.

Syndecan-3 and syndecan-4 specifically mark skeletal muscle satellite cells and are implicated in satellite cell maintenance and muscle regeneration.

B. Olwin, M. Filla, A. Rapraeger, 2001, Developmental biology.

Syndecans and Their Synstatins: Targeting an Organizer of Receptor Tyrosine Kinase Signaling at the Cell-Matrix Interface

A. Rapraeger, 2021, Frontiers in Oncology.

Cytoplasmic Domain Interactions of Syndecan-1 and Syndecan-4 with α6β4 Integrin Mediate Human Epidermal Growth Factor Receptor (HER1 and HER2)-dependent Motility and Survival*♦

Haining Jin, A. Rapraeger, Haiyao Wang, 2014, The Journal of Biological Chemistry.

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate

B. Olwin, A. Rapraeger, Bradley B. Olwin, 1992, The Journal of cell biology.

VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1

A. Rapraeger, DeannaLee M. Beauvais, K. M. Adams, 2019, Journal of Cell Science.

MST1R/RON and EGFR in a complex with syndecans sustain carcinoma S-phase progression by preventing p38MAPK activation

P. Lambert, S. Nelson, A. Rapraeger, 2018, bioRxiv.

Heparan Sulfate-related Oligosaccharides in Ternary Complex Formation with Fibroblast Growth Factors 1 and 2 and Their Receptors*

G. Giménez-Gallego, D. Spillmann, A. Rapraeger, 2006, Journal of Biological Chemistry.

Syndecan-1 mediates cell spreading in transfected human lymphoblastoid (Raji) cells

A. Rapraeger, C. Lebakken, Connie S. Lebakken, 1996, The Journal of cell biology.

Transforming growth factor (type beta) promotes the addition of chondroitin sulfate chains to the cell surface proteoglycan (syndecan) of mouse mammary epithelia

A. Rapraeger, 1989, The Journal of cell biology.

EPITHELIAL CELL SURFACE PROTEOGLYCAN: A MATRIX RECEPTOR FOR INTERSTITIAL COLLAGENS AND FIBRONECTIN

M. Jalkanen, M. Bernfield, A. Rapraeger, 1987 .

Vascular endothelial‐cadherin stimulates syndecan‐1‐coupled insulin‐like growth factor‐1 receptor and cross‐talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis

Brian J. Ell, A. Rapraeger, M. Roy, 2013, The FEBS journal.

Role of IQGAP1 in Head and Neck Carcinogenesis

Suyong Choi, P. Lambert, A. Rapraeger, 2018, bioRxiv.

Molecular interactions of syndecans during development.

A. Rapraeger, 2001, Seminars in cell & developmental biology.

In the clutches of proteoglycans: how does heparan sulfate regulate FGF binding?

A. Rapraeger, 1995, Chemistry & biology.

Syndecan-1-mediated cell spreading requires signaling by alphavbeta3 integrins in human breast carcinoma cells.

A. Rapraeger, DeannaLee M. Beauvais, 2003, Experimental cell research.

Transmembrane and Extracellular Domains of Syndecan-1 Have Distinct Functions in Regulating Lung Epithelial Migration and Adhesion*

W. Altemeier, W. Parks, A. Rapraeger, 2012, The Journal of Biological Chemistry.

Interaction of Syndecan and α6β4 Integrin Cytoplasmic Domains

A. Rapraeger, Haiyao Wang, L. Leavitt, 2010, The Journal of Biological Chemistry.

Synstatin: a selective inhibitor of the syndecan‐1‐coupled IGF1R–αvβ3 integrin complex in tumorigenesis and angiogenesis

A. Rapraeger, 2013, The FEBS journal.

Syndecan-1 regulates alphavbeta5 integrin activity in B82L fibroblasts.

A. Rapraeger, K. J. McQuade, B. Burbach, 2006, Journal of cell science.

Two hierarchies of FGF-2 signaling in heparin: mitogenic stimulation and high-affinity binding/receptor transphosphorylation.

S. Guimond, A. Rapraeger, A. Krufka, 1996, Biochemistry.

Membrane‐anchored proteoglycans of mouse macrophages: P388D1 cells express a syndecan‐4–like heparan sulfate proteoglycan and a distinct chondroitin sulfate form

C. Yeaman, A. Rapraeger, 1993, Journal of cellular physiology.

Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation

B. Olwin, A. Rapraeger, AC Rapraeger, 1991, Science.

Optimally Interacting Minds

D.D.W. Cornelison, Mark S. Filla, Heather M. Stanley, 2010 .

Localized expression of homeotic genes and the control of embryogenesis in Drosophila

M. Jalkanen, M. Bernfield, A. Rapraeger, 2008 .

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin

G. Laurie, A. Utani, A. Rapraeger, 2006, The Journal of cell biology.

Inhibiting IGF1R-mediated Survival Signaling in Head and Neck Cancer with the Peptidomimetic SSTNIGF1R

R. Kimple, A. Rapraeger, DeannaLee M. Beauvais, 2023, Cancer research communications.

Focus on molecules: syndecan-1.

G. Laurie, A. Rapraeger, Yinghui Zhang, 2011, Experimental eye research.

Reproductive Biology and Endocrinology Open Access Syndecans in Tumor Cell Adhesion and Signaling

A. Rapraeger, DeannaLee M. Beauvais, 2022 .

Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly

B. L. Allen, A. Rapraeger, 2003, The Journal of cell biology.

Syndecan-1 regulates αvβ3 and αvβ5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor

Brian J. Ell, A. Rapraeger, DeannaLee M. Beauvais, 2009, The Journal of experimental medicine.