A. Peijnenburg

发表

Sub-chronic toxicity study in rats orally exposed to nanostructured silica

H. Bouwmeester, R. Vandebriel, E. Kramer, 2014, Particle and Fibre Toxicology.

Distribution, elimination, and toxicity of silver nanoparticles and silver ions in rats after 28-day oral exposure.

H. Bouwmeester, R. Vandebriel, P. Hollman, 2012, ACS nano.

Non-animal approaches for toxicokinetics in risk evaluations of food chemicals.

Ans Punt, Hans Bouwmeester, H. Bouwmeester, 2017, ALTEX.

Predicting estrogen receptor binding of chemicals using a suite of in silico methods - Complementary approaches of (Q)SAR, molecular docking and molecular dynamics.

I. Eberini, A. Peijnenburg, A. Peijnenburg, 2019, Toxicology and applied pharmacology.

Expert opinions on the acceptance of alternative methods in food safety evaluations: Formulating recommendations to increase acceptance of non‐animal methods for kinetics

H. Bouwmeester, A. Peijnenburg, A. Punt, 2018, Regulatory toxicology and pharmacology : RTP.

Development of a QSAR Model to Predict Hepatic Steatosis Using Freely Available Machine Learning Tools.

A. Peijnenburg, N. Price, C. J, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?

B. Lindeman, A. Piersma, T. Fletcher, 2021, Critical reviews in toxicology.

Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes

P. Hendriksen, M. Groot, A. Peijnenburg, 2013, BMC Medical Genomics.

Pyrrolizidine alkaloids in food and phytomedicine: Occurrence, exposure, toxicity, mechanisms, and risk assessment - A review.

D. Schrenk, G. Lin, S. Pfuhler, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Cyclosporin A induced toxicity in mouse liver slices is only slightly aggravated by Fxr-deficiency and co-occurs with upregulation of pro-inflammatory genes and downregulation of genes involved in mitochondrial functions

A. Peijnenburg, T. Pronk, E. Szalowska, 2015, BMC Genomics.

Risk assessment of intake of pyrrolizidine alkaloids from herbal teas and medicines following realistic exposure scenarios.

I. Rietjens, P. Mulder, A. Peijnenburg, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro: A Case Study with Cyproconazole.

Bernd Wollscheid, Albert Braeuning, Alfonso Lampen, 2018, Chemical research in toxicology.

An adverse outcome pathway-based approach to assess steatotic mixture effects of hepatotoxic pesticides in vitro.

A. Lampen, A. Braeuning, B. Wollscheid, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

In vitro toxicological characterisation of the antifungal compound soybean toxin (SBTX).

P. Hendriksen, I. M. Vasconcelos, J. Oliveira, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Are effects of common ragwort in the Ames test caused by pyrrolizidine alkaloids?

K. Vrieling, R. Hoogenboom, P. Mulder, 2015, Mutation research.

Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–A Workshop Report

D. Schrenk, G. Lin, S. Pfuhler, 2021, Planta Medica.

Risk assessment for pyrrolizidine alkaloids detected in (herbal) teas and plant food supplements

I. Rietjens, P. Mulder, A. Peijnenburg, 2017, Regulatory toxicology and pharmacology : RTP.

Bioassay-directed analysis-based identification of relevant pyrrolizidine alkaloids

A. Gerssen, P. Mulder, A. Peijnenburg, 2022, Archives of Toxicology.

Strategies for analysing unintended effects in transgenic food crops

H. Noteborn, A. Peijnenburg, R. Zeleny, 2002 .

Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells

S. Kersten, R. Hoogenboom, A. Peijnenburg, 2020, Archives of Toxicology.

The safety assessment of Novel Foods and concepts to determine their safety in use

M. Poulsen, D. Müller, A. Cockburn, 2003, International journal of food sciences and nutrition.

Presence of nano-sized silica during in vitro digestion of foods containing silica as a food additive.

Agnes G. Oomen, Hans Bouwmeester, Hans J.P. Marvin, 2012, ACS nano.

Presence of potential allergy-related linear epitopes in novel proteins from conventional crops and the implication for the safety assessment of these crops with respect to the current testing of genetically modified crops.

G. Kleter, A. Peijnenburg, 2003, Plant biotechnology journal.

In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch

Jan-Peter Nap, Ad A. C. M. Peijnenburg, Gijs A. Kleter, 2005 .

Characterization of translocation of silver nanoparticles and effects on whole-genome gene expression using an in vitro intestinal epithelium coculture model.

Hans Bouwmeester, Hans J P Marvin, H. Bouwmeester, 2011, ACS nano.

Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies

A. Peijnenburg, J. Louisse, A. Punt, 2020, Chemical research in toxicology.

The impact of PPARα activation on whole genome gene expression in human precision cut liver slices

S. Kersten, A. Peijnenburg, I. Janssen, 2015, BMC Genomics.

Assessment of the safety of foods derived from genetically modified (GM) crops.

I Kimber, R W R Crevel, U Hammerling, 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Adequacy of methods for testing the safety of genetically modified foods

H. Kuiper, H. Noteborn, A. Peijnenburg, 1999, The Lancet.

Novel foods and food allergies: A review of the issues

L. Frewer, L. Gilissen, B. Gremmen, 2006 .

Screening of transgenic proteins expressed in transgenic food crops for the presence of short amino acid sequences identical to potential, IgE – binding linear epitopes of allergens

G. Kleter, A. Peijnenburg, Gijs A Kleter, 2002, BMC Structural Biology.

Prediction of in vivo genotoxicity of lasiocarpine and riddelliine in rat liver using a combined in vitro-physiologically based kinetic modelling-facilitated reverse dosimetry approach

I. Rietjens, A. Peijnenburg, L. D. de Haan, 2019, Archives of Toxicology.

Hepatotoxicity of the pesticides imazalil, thiacloprid and clothianidin - Individual and mixture effects in a 28-day study in female Wistar rats.

Vikas Kumar, A. Lampen, A. Braeuning, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Determination of genotoxic potencies of pyrrolizidine alkaloids in HepaRG cells using the γH2AX assay.

Jochem Louisse, R. Hoogenboom, P. Mulder, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells

A. Peijnenburg, R. Hoogenboom, J. Louisse, 2022, Archives of Toxicology.

Health Considerations Regarding Horizontal Transfer of Microbial Transgenes Present in Genetically Modified Crops

G. Kleter, H. Aarts, A. Peijnenburg, 2005, Journal of biomedicine & biotechnology.

New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment.

Bas J Blaauboer, Alicia Paini, Paul Jennings, 2020, ALTEX.

Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells

L. Duivenvoorde, M. van der Zande, A. Peijnenburg, 2020, Archives of Toxicology.

Towards harmonization of test methods for in vitro hepatic clearance studies.

Sandra Coecke, Ans Punt, Jochem Louisse, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

Current Insights into Monitoring, Bioaccumulation, and Potential Health Effects of Microplastics Present in the Food Chain

A. Koelmans, R. Peters, M. van der Zande, 2020, Foods.

Sub-chronic toxicity study in rats orally exposed to nanostructured silica

H. Bouwmeester, R. Vandebriel, E. Kramer, 2014, Particle and Fibre Toxicology.

Feasibility of a liver transcriptomics approach to assess bovine treatment with the prohormone dehydroepiandrosterone (DHEA)

P. Hendriksen, M. Groot, A. Peijnenburg, 2010, BMC veterinary research.

A. Peijnenburg, T. Pronk, E. Szalowska, 2015, BMC Genomics.

Different responses of Caco-2 and MCF-7 cells to silver nanoparticles are based on highly similar mechanisms of action

Hans Bouwmeester, Marco P Monopoli, Meike van der Zande, 2016, Nanotoxicology.

Food safety knowledge on the Bt mutant protein Cry8Ka5 employed in the development of coleopteran-resistant transgenic cotton plants

M. F. Grossi-de-Sá, A. Peijnenburg, D. Farias, 2015, Bioengineered.

AhR-agonistic, anti-androgenic, and anti-estrogenic potencies of 2-isopropylthioxanthone (ITX) as determined by in vitro bioassays and gene expression profiling.

R. Hoogenboom, A. Peijnenburg, H. Baykus, 2010, Toxicology in vitro : an international journal published in association with BIBRA.