B. O’Keefe

发表

Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products

Jason R. Evans, L. McShane, Yingdong Zhao, 2020, Molecular oncology.

Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions.

J. Mcmahon, P. Seeberger, D. Ratner, 2004, Chemistry & biology.

Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins

J. Reed, M. Walters, K. Welsh, 2014, Journal of biomolecular screening.

Activity of and Effect of Subcutaneous Treatment with the Broad-Spectrum Antiviral Lectin Griffithsin in Two Laboratory Rodent Models

D. Montefiori, K. Palmer, G. Brock, 2013, Antimicrobial Agents and Chemotherapy.

Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding

Alexander Wlodawer, Barry R O'Keefe, Barbara Giomarelli, 2006, Structure.

Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N.

K. Gustafson, D. Smee, L. Gubareva, 2008, Antiviral research.

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus

S. Subramaniam, A. Wlodawer, J. Meyerson, 2015, Retrovirology.

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

K. Palmer, J. Rose, S. Nichol, 2020, The Journal of infectious diseases.

Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

L K Pannell, L. Pannell, K. Gustafson, 1997, Antimicrobial agents and chemotherapy.

A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium.

L. Pannell, M. Boyd, B. O’Keefe, 2003, Biochemistry.

Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus.

Mike Bray, Angela M Gronenborn, Barry R O'Keefe, 2003, Antiviral research.

Potent Anti-Influenza Activity of Cyanovirin-N and Interactions with Viral Hemagglutinin

K. Gustafson, M. Boyd, D. Smee, 2003, Antimicrobial Agents and Chemotherapy.

Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.*

Barry R O'Keefe, Robert W Buckheit, Scott Bringans, 2005, Journal of Biological Chemistry.

The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures.

Alexander Wlodawer, Angela M Gronenborn, Barry R O'Keefe, 2002, Structure.

Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods.

Brice A P Wilson, K. Gustafson, C. J. Henrich, 2020, Phytochemistry.

Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm

Raziel A. Ordóñez, B. Clotet, R. Twyman, 2018, Proceedings of the National Academy of Sciences.

Analysis of the interaction between the HIV-inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41.

M. Boyd, D. Xie, I. Chaiken, 2000, Molecular pharmacology.

Harnessing Natural Product Diversity for Fluorophore Discovery: Naturally Occurring Fluorescent Hydroxyanthraquinones from the Marine Crinoid Pterometra venusta.

K. Gustafson, B. O’Keefe, H. Bokesch, 2018, Journal of Natural Products.

The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells.

L. Morris, J. Mcmahon, E. Gray, 2012, Virology.

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture

J. Montgomery, S. Nichol, C. Spiropoulou, 2020, Frontiers in Cellular and Infection Microbiology.

Neopetrothiazide: An Intriguing Pentacyclic Thiazide Alkaloid from the Sponge Neopetrosia sp.

J. Khan, K. Gustafson, B. Gryder, 2021, Organic letters.

High Throughput Screening for Cyanovirin-N Mimetics Binding to HIV-1 gp 41

M. Boyd, D. Robbins, J. Beutler, 2002 .

High Throughput Screening for Cyanovirin-N Mimetics Binding to HIV-1 gp4l

M. Boyd, J. Mcmahon, D. Robbins, 2002, Journal of biomolecular screening.

Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti‐HIV microbicide

J. Mcmahon, Yonghou Jiang, K. Palmer, 2007, Journal of medical primatology.

Anti-HIV microbicide development: targeting the virus is the key

B. O’Keefe, 2011 .

Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model

P. Robbins, J. Samuelson, W. Secor, 2015, PloS one.

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.

M. Bray, J. Mcmahon, J. Huggins, 2014, Antiviral research.

Antiviral Lectins from Red and Blue-Green Algae Show Potent In Vitro and In Vivo Activity against Hepatitis C Virus

Y. Takebe, K. Ramessar, J. Mcmahon, 2012, PloS one.

The Use of Nonclassical Techniques in the Production of Secondary Metabolites by Plant Tissue Cultures

C. Beecher, B. O’Keefe, 1993 .

Structure of a lectin from the sea mussel Crenomytilus grayanus (CGL).

A. Wlodawer, J. Lubkowski, B. O’Keefe, 2015, Acta crystallographica. Section F, Structural biology communications.

Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.

Brice A P Wilson, Y. Pommier, K. Gustafson, 2020, Journal of the American Chemical Society.

Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea

K. Gustafson, C. J. Henrich, R. Cichewicz, 2021, Molecules.

Potent anti-HIV activity of scytovirin domain 1 peptide

J. Mcmahon, R. Byrd, B. O’Keefe, 2006, Peptides.

Influenza a (H1N1) Virus Resistance to Cyanovirin-N Arises Naturally during Adaptation to Mice and by Passage in Cell Culture in the Presence of the Inhibitor

M. Boyd, D. Smee, L. Gubareva, 2007, Antiviral chemistry & chemotherapy.

Griffithsin and Carrageenan Combination Results in Antiviral Synergy against SARS-CoV-1 and 2 in a Pseudoviral Model

James O. Sailer, B. O’Keefe, Neeharika Verma, 2021, Marine drugs.

Abstract A174: High‐throughput screening for natural product inhibitors of human tyrosyl‐DNA‐phosphodiesterase (Tdp‐1)

Jason R. Evans, Y. Pommier, C. Marchand, 2009 .

Isolation and Characterization of S-Adenosyl-L-Methionine:Tetrahydroberberine-cis-N-Methyltransferase from Suspension Cultures of Sanguinaria canadensis L

B. O’Keefe, C. Beecher, 1994, Plant physiology.

National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

Jason R. Evans, K. Gustafson, C. J. Henrich, 2020, ACS chemical biology.

(-)-Neocaryachine, an Antiproliferative Pavine Alkaloid from Cryptocarya laevigata, Induces DNA Double-Strand Breaks.

D. Newman, K. Lee, B. O’Keefe, 2017, Journal of natural products.

Contemporary Approaches to the Discovery and Development of Broad-Spectrum Natural Product Prototypes for the Control of Coronaviruses

G. Hardiman, R. Schinazi, B. Wolf, 2021, Journal of natural products.

Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta.

S. Pomponi, L. Pannell, M. Boyd, 1997, European journal of biochemistry.

Cytotoxic Metabolites from an Australian Collection of the Sponge Jaspis Species

M. Boyd, B. O’Keefe, A. Groweiss, 1999 .

Prenylated Acetophloroglucinol Dimers from Acronychia trifoliolata: Structure Elucidation and Total Synthesis.

D. Newman, K. Lee, B. O’Keefe, 2019, Journal of natural products.

Acetophenone Monomers from Acronychia trifoliolata.

D. Newman, K. Lee, B. O’Keefe, 2016, Journal of natural products.

Isolation and characterization of anti‐HIV peptides from Dorstenia contrajerva and Treculia obovoidea

J. Mcmahon, J. Beutler, B. O’Keefe, 2004, FEBS letters.

NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening.

David J Newman, Tanja Grkovic, Christopher C Thornburg, 2018, ACS chemical biology.

Creating and screening natural product libraries.

Tanja Grkovic, Curtis J Henrich, Brice A P Wilson, 2020, Natural product reports.

Isolation, Structure Elucidation, and Antiproliferative Activity of Butanolides and Lignan Glycosides from the Fruit of Hernandia nymphaeifolia

S. Fukuyoshi, D. Newman, K. Lee, 2019, Molecules.

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation.

S. Lockett, Cheryl L. Thomas, E. Goncharova, 2019, Cell chemical biology.

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina.

W. M. Hewitt, K. Gustafson, J. Mcmahon, 2017, Organic letters.

Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines.

R. Cichewicz, S. Cai, T. Grkovic, 2019, Journal of natural products.

The Antiretroviral Lectin Cyanovirin-N Targets Well-Known and Novel Targets on the Surface of Entamoeba histolytica Trophozoites

P. Robbins, J. Samuelson, J. Cui, 2010, Eukaryotic Cell.

Biologically active proteins from natural product extracts.

B. O’Keefe, 2001, Journal of natural products.

Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea.

D. Powell, R. Cichewicz, S. Cai, 2020, Journal of natural products.

Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium.

A. Wlodawer, J. Mcmahon, I. Botos, 2006, Protein expression and purification.

Spiro[3.5]nonenyl Meroterpenoid Lactones, Cryptolaevilactones G-L, an Ionone Derivative, and Total Synthesis of Cryptolaevilactone M from Cryptocarya laevigata.

S. Fukuyoshi, D. Newman, K. Lee, 2019, Journal of natural products.

CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells.

J. Doench, Huiyun Liang, R. Cichewicz, 2020, Journal of natural products.

An Integrated Strategy for the Detection, Dereplication, and Identification of DNA-Binding Biomolecules from Complex Natural Product Mixtures.

Huiyun Liang, R. Cichewicz, S. Cai, 2020, Journal of natural products.

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

E. Martinelli, B. O’Keefe, O. Mizenina, 2015, Antimicrobial Agents and Chemotherapy.

Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53.

Yili Yang, A. Weissman, J. Mcmahon, 2008, Bioorganic & medicinal chemistry.

Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity.

M. Wendeler, S. L. Le Grice, Jennifer T. Miller, 2008, ACS chemical biology.

Stable Vindoline Production in Transformed Cell Cultures of Catharanthus roseus

J. Gills, G. Mahady, C. Beecher, 1997 .

Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate

N. Matoba, K. Palmer, D. Schols, 2011, PloS one.

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

D. Meyerholz, J. Mcmahon, C. Wohlford-Lenane, 2009, Journal of Virology.

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

David C. Montefiori, Barry R. O'Keefe, D. Montefiori, 2009, Proceedings of the National Academy of Sciences.

lsolation and Characterization of S-Adenosyl-L-Methionine:Tetrahydroberberine-cis-N-Methyltransferase from Suspension Cultures of Sanguinaria canadensis 1.’

C. Beecher, B. O’Keefe, 2002 .

NMR Characterization of Rearranged Staurosporine Aglycone Analogues from the Marine Sponge Damiria sp.

K. Gustafson, C. J. Henrich, P. Kittakoop, 2019, Magnetic resonance in chemistry : MRC.

Suberitamides A–C, Aryl Alkaloids from a Pseudosuberites sp. Marine Sponge that Inhibit Cbl-b Ubiquitin Ligase Activity

K. Gustafson, S. Lipkowitz, B. O’Keefe, 2020, Marine drugs.

Structures of the Complexes of a Potent Anti-HIV Protein Cyanovirin-N and High Mannose Oligosaccharides*

Alexander Wlodawer, Peter H Seeberger, Barry R O'Keefe, 2002, The Journal of Biological Chemistry.

In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors

E. Goncharova, S. Lipkowitz, B. O’Keefe, 2021, SLAS discovery : advancing life sciences R & D.

The NCI library of traditional Chinese medicinal plant extracts - Preliminary assessment of the NCI-60 activity and chemical profiling of selected species.

Jason R. Evans, L. Jia, D. Newman, 2019, Fitoterapia.

Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H

X. Zhuang, M. Wendeler, S. L. Le Grice, 2010, Antimicrobial Agents and Chemotherapy.

Antiviral lectins: Selective inhibitors of viral entry

K. Ramessar, B. O’Keefe, C. Mitchell, 2017, Antiviral Research.

Corymbulosins D-H, 2-Hydroxy- and 2-Oxo-clerodane Diterpenes from the Bark of Laetia corymbulosa.

S. Fukuyoshi, D. Newman, K. Lee, 2017, Journal of natural products.

Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

A. Wlodawer, Z. Dauter, Cheryl L. Thomas, 2010, Structure.

Identification of Inhibitors for MDM2 Ubiquitin Ligase Activity from Natural Product Extracts by a Novel High-Throughput Electrochemiluminescent Screen

Pankaj Oberoi, Jirouta Kitagaki, John A. Beutler, 2008, Journal of biomolecular screening.

Differential Inhibitory Effects of Cyanovirin-N, Griffithsin, and Scytovirin on Entry Mediated by Envelopes of Gammaretroviruses and Deltaretroviruses

F. Ruscetti, D. Bertolette, A. Rein, 2013, Journal of Virology.

Inhibiting Hdm2 and ubiquitin-activating enzyme: targeting the ubiquitin conjugating system in cancer.

A. Weissman, J. Beutler, B. O’Keefe, 2008, Ernst Schering Foundation symposium proceedings.

Probing Protein–Carbohydrate Interactions with Microarrays of Synthetic Oligosaccharides

Milan Mrksich, Peter H Seeberger, Barry R O'Keefe, 2004, Chembiochem : a European journal of chemical biology.

Rice endosperm is cost‐effective for the production of recombinant griffithsin with potent activity against HIV

P. Christou, T. Capell, E. Vamvaka, 2016, Plant biotechnology journal.

Engineering soya bean seeds as a scalable platform to produce cyanovirin‐N, a non‐ARV microbicide against HIV

K. Ramessar, J. Mcmahon, N. B. da Cunha, 2015, Plant biotechnology journal.

A New Bispyrroloiminoquinone Alkaloid From a Thai Collection of Clavelina sp.

Jason R. Evans, P. Kittakoop, C. Mahidol, 2021 .

Binding of the Mannose-Specific Lectin, Griffithsin, to HIV-1 gp120 Exposes the CD4-Binding Site

L. Morris, P. Moore, J. Mcmahon, 2011, Journal of Virology.

Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN.

L. Morris, P. Moore, M. Nonyane, 2013, Virology.

A Designed “Nested” Dimer of Cyanovirin-N Increases Antiviral Activity

A. Bobkov, G. Ghirlanda, B. O’Keefe, 2016, Viruses.

Development of a fluorescent microplate assay for determining cyanovirin-N levels in plasma

M. Boyd, B. O’Keefe, S. Bringans, 2004, Analytical and bioanalytical chemistry.

Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization.

A. Gronenborn, M. Boyd, P. Seeberger, 2002, Chemistry & biology.

Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner.

M. Boyd, J. Mcmahon, B. O’Keefe, 2001, Molecular pharmacology.

Selective interactions of the human immunodeficiency virus-inactivating protein cyanovirin-N with high-mannose oligosaccharides on gp120 and other glycoproteins.

M. Boyd, B. O’Keefe, S. Shenoy, 2001, The Journal of pharmacology and experimental therapeutics.

Physicochemical characterization of the recombinant lectin scytovirin and microbicidal activity of the SD1 domain produced in rice against HIV-1

S. Marfil, P. Christou, T. Capell, 2022, Plant Cell Reports.

Mannose-rich glycosylation patterns on HIV-1 subtype C gp 120 and sensitivity to the lectins

S. Karim, L. Morris, P. Moore, 2011 .

Topology of the disulfide bonds in the antiviral lectin scytovirin

A. Wlodawer, Weirong Yuan, Wuyuan Lu, 2010, Protein science : a publication of the Protein Society.

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin.

S. Karim, L. Morris, P. Moore, 2010, Virology.

Atomic‐resolution crystal structure of the antiviral lectin scytovirin

Zbigniew Dauter, Alexander Wlodawer, Tinoush Moulaei, 2007, Protein science : a publication of the Protein Society.

The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors.

J. Mcmahon, R. Byrd, P. Seeberger, 2007, Journal of molecular biology.

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin† ‡

R. Dwek, A. Wlodawer, M. Wormald, 2007, Proteins.

Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel

B. Friedland, Yupu Liang, R. Fichorova, 2022, PloS one.

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

W. Heneine, M. Peet, M. Lal, 2018, Nature Communications.

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

D. Meyerholz, J. Mcmahon, C. Wohlford-Lenane, 2010, Journal of Virology.

Resistance of Human Immunodeficiency Virus Type 1 to the High-Mannose Binding Agents Cyanovirin N and Concanavalin A

L. Stamatatos, E. De Clercq, C. Pannecouque, 2005, Journal of Virology.

The HIV-inactivating protein, cyanovirin-N, does not block gp120-mediated virus-to-cell binding.

K. Nagashima, M. Boyd, J. Mcmahon, 1998, Biochemical and biophysical research communications.

Development of a Cyanovirin-N-HIV-1 gpl20 Binding Assay for High Throughput Screening of Natural Product Extracts by Time-Resolved Fluorescence

M. Boyd, J. Mcmahon, J. Beutler, 2000, Journal of biomolecular screening.

Isolation and characterization of adociavirin, a novel HIV‐inhibitory protein from the sponge Adocia sp. 1

M. Boyd, J. Mcmahon, J. Beutler, 1998, FEBS letters.

Design and initial characterization of a circular permuted variant of the potent HIV‐inactivating protein cyanovirin‐N

A. Gronenborn, M. Boyd, J. Louis, 2002, Proteins.

An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

G. Rao, G. Sittampalam, R. Lunsford, 2022, bioRxiv.

Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro

P. Christou, T. Capell, E. Vamvaka, 2016, Plant Cell Reports.

Suggestive Evidence for Darwinian Selection against Asparagine-Linked Glycans of Plasmodium falciparum and Toxoplasma gondii

P. Robbins, J. Samuelson, J. Dvorin, 2009, Eukaryotic Cell.

Gene-silencing suppressors for high-level production of the HIV-1 entry inhibitor griffithsin in Nicotiana benthamiana

G. S. Prado, C. R. Soccol, M. Faheem, 2018, Process Biochemistry.

Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays

S. L. Le Grice, Joanna Sztuba-Solinska, Peter C. Gareiss, 2014, Journal of the American Chemical Society.

Isolation and characterization of Myrianthus holstii lectin, a potent HIV-1 inhibitory protein from the plant Myrianthus holstii.

L. Pannell, M. Boyd, M. Currens, 2000 .

Erythrofordins D and E, two new cassaine-type diterpenes from Erythrophleum suaveolens.

Jason R. Evans, M. Hollingshead, Myrtle A. Davis, 2019, Bioorganic & medicinal chemistry letters.

Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana

K. Gustafson, E. Goncharova, S. Lipkowitz, 2021, Marine drugs.

Discovery and Characterization of a Biologically Active Non–ATP-Competitive p38 MAP Kinase Inhibitor

Jason R. Evans, P. Wipf, E. Goncharova, 2016, Journal of biomolecular screening.

Cyclonellin, a new cyclic octapeptide from the marine sponge Axinella carteri.

L. Pannell, K. Gustafson, M. Boyd, 2004, Journal of natural products.

Synthesis and biological evaluation of the first dual tyrosyl-DNA phosphodiesterase I (Tdp1)-topoisomerase I (Top1) inhibitors.

Y. Pommier, A. Stephen, R. Fisher, 2012, Journal of medicinal chemistry.

Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine

A. Wlodawer, B. O’Keefe, N. E. Ziółkowska, 2007, Protein science : a publication of the Protein Society.

Encoded fiber-optic microsphere arrays for probing protein-carbohydrate interactions.

David R Walt, Peter H Seeberger, Barry R O'Keefe, 2003, Angewandte Chemie.

Targeting Protein Translation by Rocaglamide and Didesmethylrocaglamide to Treat MPNST and Other Sarcomas

A. Kinghorn, M. Hollingshead, Sarah S. Burns, 2019, Molecular Cancer Therapeutics.

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

Jason R. Evans, Y. Pommier, E. Goncharova, 2017, SLAS discovery : advancing life sciences R & D.

ENGINEERING DNA TOPOLOGY WITH LOCKED NUCLEOSIDES: A STRUCTURAL STUDY

A. Bax, Justin Wu, V. Marquez, 2005, Nucleosides, nucleotides & nucleic acids.

Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2

S. Marfil, R. Twyman, A. Tanuri, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of Choerospondias axillaris.

Huiyun Liang, R. Cichewicz, T. Grkovic, 2020, Journal of natural products.

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities.

L. Staudt, K. Gustafson, C. J. Henrich, 2019, Journal of natural products.

The canSAR data hub for drug discovery.

Barry R O'Keefe, W. Figg, C. Chau, 2016, The Lancet. Oncology.

Dentithecamides A-H, Diacylated Zoanthoxanthin Derivatives with PAX3-FOXO1 Inhibitory Activity from the Hydroid Dentitheca habereri.

Jun S. Wei, K. Gustafson, Wei Jiang, 2022, Journal of natural products.

Corymbulosins I-W, Cytotoxic Clerodane Diterpenes from the Bark of Laetia corymbulosa.

S. Fukuyoshi, D. Newman, K. Lee, 2018, The Journal of organic chemistry.

Antiproliferative Alkaloids from Alangium longiflorum, an Endangered Tropical Plant Species.

D. Newman, K. Lee, B. O’Keefe, 2018, Journal of natural products.

Isolation and characterization of Myrianthus holstii lectin, a potent HIV-1 inhibitory protein from the plant Myrianthus holstii(1).

L. Pannell, M. Boyd, M. Currens, 2000, Journal of natural products.

Insight into mithramycin disruption of ETS transcription leads to improved understanding of more selective analogs.

B. O’Keefe, G. Woldemichael, 2021, Structure.