A. Roschke

发表

Karyotypic complexity of the NCI-60 drug-screening panel.

J. Weinstein, D. Scudiero, G. Tonon, 2003, Cancer research.

Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping.

William C Reinhold, John N Weinstein, Yves Pommier, 2003, Cancer research.

Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells

Ruili Huang, Anders Wallqvist, D. Covell, 2005, Molecular Cancer Therapeutics.

Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel

William C Reinhold, Fuad G. Gwadry, Wen-Lin Kuo, 2006, Molecular Cancer Therapeutics.

Chromosomal instability is associated with higher expression of genes implicated in epithelial-mesenchymal transition, cancer invasiveness, and metastasis and with lower expression of genes involved in cell cycle checkpoints, DNA repair, and chromatin maintenance.

J. Weinstein, S. Lababidi, I. Kirsch, 2008, Neoplasia.

14-3-3 epsilon has no homology to LIS1 and lies telomeric to it on chromosome 17p13.3 outside the Miller-Dieker syndrome chromosome region.

D. Ledbetter, A. Tanigami, S. Chong, 1996, Genome research.

Identification of a novel paternally expressed transcript adjacent to snRPN in the Prader-Willi syndrome critical region.

D. Ledbetter, J. Sutcliffe, S. Christian, 1996, Genome research.

Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors

B. Barlogie, J. Shaughnessy, J. Sawyer, 2008, Genes, chromosomes & cancer.

Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma.

P. L. Bergsagel, W. Kuehl, I. Kirsch, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Efficient repair of DNA double-strand breaks in malignant cells with structural instability.

A. Roschke, K. Nakahara, Zhenhua Zhang, 2010, Mutation research.

A complete set of human telomeric probes and their clinical application

D. Ledbetter, R. Regan, J. Flint, 1996, Nature Genetics.

Targeting karyotypic complexity and chromosomal instability of cancer cells.

I. Kirsch, A. Roschke, 2010, Current drug targets.

Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability.

A. Schäffer, G. Tonon, I. Kirsch, 2002, Neoplasia.

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell–like diffuse large B cell lymphoma

L. Staudt, A. Rosenwald, W. Chan, 2007, The Journal of experimental medicine.

A revision of the lissencephaly and Miller-Dieker syndrome critical regions in chromosome 17p13.3.

D. Ledbetter, A. Tanigami, W. Dobyns, 1997, Human molecular genetics.

Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines.

P. Meltzer, F. Kaye, E. Rozenblum, 2013, Cancer genetics.

Multi-Layered Cancer Chromosomal Instability Phenotype

E. Rozenblum, A. Roschke, 2013, Front. Oncol..

Targeting Cancer Cells by Exploiting Karyotypic Complexity and Chromosomal Instability

I. Kirsch, A. Roschke, 2005, Cell cycle.

Karyotypic "state" as a potential determinant for anticancer drug discovery.

J. Weinstein, G. Tonon, K. Bussey, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors

Y. Asmann, P. L. Bergsagel, A. Roschke, 2016, Nucleic acids research.

Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells

P. Meltzer, Y. Zhu, M. Pineda, 2019, Scientific Reports.

Promiscuous Rearrangements of the MYC Locus Hijack Enhancers and Super-Enhancers to Dysregulate MYC Expression in Multiple Myeloma

J. Keats, R. Fonseca, S. V. Van Wier, 2014, Leukemia.

Generation of Gross Chromosomal Rearrangements by a Single Engineered DNA Double Strand Break

A. Roschke, Zhenhua Zhang, T. Varga, 2017, Scientific Reports.

Spectral karyotyping combined with locus‐specific FISH simultaneously defines genes and chromosomes involved in chromosomal translocations

I. Kirsch, A. Roschke, K. Stover, 2000, Genes, chromosomes & cancer.

Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells

P. Meltzer, Y. Zhu, R. Walker, 2019, Scientific Reports.

Prognostic significance of cell cycle proteins and genomic instability in borderline, early and advanced stage ovarian carcinomas

T. Ried, L. McShane, G. Auer, 2000, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society.

Corrigendum: A complete set of human telomeric probes and their clinical application

D. Ledbetter, R. Regan, J. Flint, 1996, Nature Genetics.

Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma.

P. L. Bergsagel, W. Kuehl, I. Kirsch, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Complex IGH rearrangements in multiple myeloma: Frequent detection discrepancies among three different probe sets

A. Roschke, Y. Demchenko, Gina Kim, 2014, Genes, chromosomes & cancer.

Karyotypic complexity of the NCI-60 drug-screening panel.

J. Weinstein, D. Scudiero, G. Tonon, 2003, Cancer research.

Generation of Gross Chromosomal Rearrangements by a Single Engineered DNA Double Strand Break

A. Roschke, T. Varga, Zhenhua Zhang, 2017, Scientific Reports.

Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor

P. Meltzer, T. Ried, E. Rozenblum, 2017, PloS one.

Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma

Caleb K. Stein, S. Lonial, B. Barwick, 2023, Blood cancer discovery.