A. Kaneko

发表

Tocilizumab in rheumatoid arthritis: efficacy, safety and its place in therapy

A. Kaneko, 2013, Therapeutic advances in chronic disease.

Effects of Tokishakuyakusan on Regeneration of Murine Olfactory Neurons In Vivo and In Vitro

Yukari Nakamura, H. Sakata-Haga, T. Hatta, 2019, Chemical senses.

Involvement of cAMP responsive element binding protein (CREB) in the synovial cell hyperfunction in patients with rheumatoid arthritis.

A. Kaneko, T. Asai, M. Takeno, 2000, Clinical and experimental rheumatology.

Consensus-based identification of factors related to false-positives in ultrasound scanning of synovitis and tenosynovitis

Tamotsu Kamishima, T. Sumida, Hiromu Ito, 2016, Modern rheumatology.

Possible involvement of suppression of Th2 differentiation in the anti-allergic effect of Sho-seiryu-to in mice.

A. Ishige, Masahiro Yamamoto, A. Kaneko, 2002, Japanese journal of pharmacology.

Radiological features and therapeutic responses of pulmonary nontuberculous mycobacterial disease in rheumatoid arthritis patients receiving biological agents: a retrospective multicenter study in Japan

T. Johkoh, S. Tasaka, K. Hatta, 2012 .

T. Johkoh, S. Tasaka, K. Hatta, 2011, Modern rheumatology.

Oral Administration of the Japanese Traditional Medicine Keishibukuryogan-ka-yokuinin Decreases Reactive Oxygen Metabolites in Rat Plasma: Identification of Chemical Constituents Contributing to Antioxidant Activity

K. Sekiguchi, A. Kaneko, Takuji Yamaguchi, 2017, Molecules.

Clinical effectiveness and long-term retention of abatacept in elderly rheumatoid arthritis patients: Results from a multicenter registry system

A. Kaneko, T. Kojima, N. Takahashi, 2018, Modern rheumatology.

Analysis of perioperative clinical features and complications after orthopaedic surgery in rheumatoid arthritis patients treated with tocilizumab in a real-world setting: results from the multicentre TOcilizumab in Perioperative Period (TOPP) study

A. Murasawa, S. Momohara, H. Matsuno, 2013 .

A. Murasawa, S. Momohara, H. Matsuno, 2013, Modern rheumatology.

Pharmacokinetic Study of Bioactive Flavonoids in the Traditional Japanese Medicine Keigairengyoto Exerting Antibacterial Effects against Staphylococcus aureus

S. Aiba, A. Kaneko, K. Yamasaki, 2018, International journal of molecular sciences.

Use of a 12-week observational period for predicting low disease activity at 52 weeks in RA patients treated with abatacept: a retrospective observational study based on data from a Japanese multicentre registry study.

A. Kaneko, T. Kojima, N. Takahashi, 2015, Rheumatology.

Longterm Efficacy and Safety of Abatacept in Patients with Rheumatoid Arthritis Treated in Routine Clinical Practice: Effect of Concomitant Methotrexate after 24 Weeks

A. Kaneko, T. Kojima, N. Takahashi, 2015, The Journal of Rheumatology.

Study protocol of a multicenter registry of patients with rheumatoid arthritis starting biologic therapy in Japan: Tsurumai Biologics Communication Registry (TBCR) Study

A. Kaneko, M. Kojima, T. Kojima, 2012, Modern rheumatology.

Serum glutamic oxalacetic transaminase/glutamic pyruvic transaminase ratios in hepatocellular carcinoma

M. Kojiro, A. Kaneko, K. Okuda, 1977, Cancer.

The Japanese herbal medicine Hangeshashinto enhances oral keratinocyte migration to facilitate healing of chemotherapy-induced oral ulcerative mucositis

Y. Higami, S. Hitomi, K. Ono, 2020, Scientific Reports.

Baicalin suppresses type 2 immunity through breaking off the interplay between mast cell and airway epithelial cell.

S. Fujieda, A. Kaneko, Kanako Yoshida, 2020, Journal of ethnopharmacology.

Anthocyans Fail to Suppress Transformation of Aryl Hydrocarbon Receptor Induced by Dioxin

H. Ashida, S. Nishiumi, A. Kaneko, 2005, Bioscience, biotechnology, and biochemistry.

Plasma Pharmacokinetics of Polyphenols in a Traditional Japanese Medicine, Jumihaidokuto, Which Suppresses Propionibacterium acnes-Induced Dermatitis in Rats

K. Sekiguchi, Y. Kase, A. Kaneko, 2015, Molecules.

Evidence for neural regulation of inflammatory synovial cell functions by secreting calcitonin gene-related peptide and vasoactive intestinal peptide in patients with rheumatoid arthritis.

A. Kaneko, T. Asai, Y. Takeba, 1999, Arthritis and rheumatism.

Influences of anti-tumour necrosis factor agents on postoperative recovery in patients with rheumatoid arthritis

A. Kaneko, T. Kojima, N. Ishiguro, 2010, Clinical Rheumatology.

Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

H. Ashida, M. Kawase, N. Fujitake, 2009, Journal of bioscience and bioengineering.

Association between seropositivity and discontinuation of tumor necrosis factor inhibitors due to ineffectiveness in rheumatoid arthritis

A. Kaneko, T. Kojima, N. Takahashi, 2019, Clinical Rheumatology.

Concomitant methotrexate and tacrolimus augment the clinical response to abatacept in patients with rheumatoid arthritis with a prior history of biological DMARD use

A. Kaneko, T. Kojima, N. Takahashi, 2015, Rheumatology International.

Drug retention rates of second biologic agents after switching from tumor necrosis factor inhibitors for rheumatoid arthritis in Japanese patients on low-dose methotrexate or without methotrexate

A. Kaneko, T. Kojima, N. Takahashi, 2015, Modern rheumatology.

Twenty-four-week clinical results of adalimumab therapy in Japanese patients with rheumatoid arthritis: retrospective analysis for the best use of adalimumab in daily practice

A. Kaneko, T. Kojima, K. Terabe, 2013, Modern rheumatology.

Clinical efficacy of abatacept in Japanese rheumatoid arthritis patients

A. Kaneko, T. Kojima, N. Takahashi, 2013, Modern rheumatology.

Prolactin locally produced by synovium infiltrating T lymphocytes induces excessive synovial cell functions in patients with rheumatoid arthritis.

H. Nagafuchi, A. Kaneko, T. Asai, 1999, The Journal of rheumatology.

Characterization of Tissue Outgrowth Developed in vitro in Patients with Rheumatoid Arthritis: Involvement of T Cells in the Development of Tissue Outgrowth

H. Nagafuchi, A. Kaneko, T. Asai, 2000, International Archives of Allergy and Immunology.

Wogonin Attenuates Ovalbumin Antigen-Induced Neutrophilic Airway Inflammation by Inhibiting Th17 Differentiation

S. Matsushita, K. Nakagome, A. Kaneko, 2014, International journal of inflammation.

Analysis of retinoblastoma for human adenovirus type 12 genome

A. Kaneko, K. Fujinaga, N. Suzuki, 2005, Graefe's Archive for Clinical and Experimental Ophthalmology.

Endorphin and enkephalin ameliorate excessive synovial cell functions in patients with rheumatoid arthritis.

A. Kaneko, T. Asai, Y. Takeba, 2001, The Journal of rheumatology.

Longterm Retention Rate and Risk Factors for Adalimumab Discontinuation Due To Efficacy and Safety in Japanese Patients with Rheumatoid Arthritis: An Observational Cohort Study

A. Kaneko, T. Kojima, N. Takahashi, 2016, The Journal of Rheumatology.

A retrospective analysis of the relationship between anti-cyclic citrullinated peptide antibody and the effectiveness of abatacept in rheumatoid arthritis patients

M. Ando, S. Hirata, A. Kaneko, 2020, Scientific Reports.

Steroid therapy and renal dysfunction are independently associated with serum levels of matrix metalloproteinase-3 in patients with rheumatoid arthritis

A. Kaneko, D. Kida, Y. Hattori, 2018, Modern rheumatology.

Normal serum matrix metalloproteinase-3 levels can be used to predict clinical remission and normal physical function in patients with rheumatoid arthritis

A. Kaneko, D. Kida, Y. Hattori, 2017, Clinical Rheumatology.

Development and validation of a new radiographic scoring system to evaluate bone and cartilage destruction and healing of large joints with rheumatoid arthritis: ARASHI (Assessment of rheumatoid arthritis by scoring of large joint destruction and healing in radiographic imaging) study

K. Nishida, A. Kaneko, I. Matsushita, 2013, Modern rheumatology.

Predictors of biologic discontinuation due to insufficient response in patients with rheumatoid arthritis who achieved clinical remission with biologic treatment: A multicenter observational cohort study

A. Kaneko, T. Kojima, N. Takahashi, 2018, Modern rheumatology.

Risk of postoperative complications in rheumatoid arthritis relevant to treatment with biologic agents: a report from the Committee on Arthritis of the Japanese Orthopaedic Association

S. Momohara, K. Nishida, K. Takagishi, 2011, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

Predictive factors for achieving low disease activity at 52 weeks after switching from tumor necrosis factor inhibitors to abatacept: results from a multicenter observational cohort study of Japanese patients

A. Kaneko, T. Kojima, N. Takahashi, 2015, Clinical Rheumatology.

Longterm Retention Rate and Risk Factor for Discontinuation Due to Insufficient Efficacy and Adverse Events in Japanese Patients with Rheumatoid Arthritis Receiving Etanercept Therapy

A. Kaneko, T. Kojima, N. Takahashi, 2014, The Journal of Rheumatology.

Clinical efficacy of abatacept, tocilizumab, and etanercept in Japanese rheumatoid arthritis patients with inadequate response to anti-TNF monoclonal antibodies

A. Kaneko, T. Kojima, N. Takahashi, 2014, Clinical Rheumatology.

AB0246 Study of the Antibody Titer by Influenza Vaccination in Rheumatoid Arthritis Patients Treated with Biological Agents -Examination of Multiple Dose-

A. Kaneko, D. Kida, T. Sato, 2014 .

Inhibition of Human Kallikrein 5 Protease by Triterpenoids from Natural Sources

S. Aiba, A. Kaneko, K. Yamasaki, 2017, Molecules.

Daikenchuto (TU‐100) shapes gut microbiota architecture and increases the production of ginsenoside metabolite compound K

E. Chang, Y. Kohgo, M. Musch, 2016, Pharmacology research & perspectives.

Keigairengyoto, a traditional Japanese medicine, promotes bacterial clearance by activating innate immune cells in mouse cutaneous infection models

S. Aiba, K. Sekiguchi, A. Kaneko, 2017, Trends in Immunotherapy.

Glucuronides of phytoestrogen flavonoid enhance macrophage function via conversion to aglycones by β‐glucuronidase in macrophages

R. Yakabe, S. Aiba, K. Sekiguchi, 2017, Immunity, inflammation and disease.

Suppression of Propionibacterium acnes-Induced Dermatitis by a Traditional Japanese Medicine, Jumihaidokuto, Modifying Macrophage Functions

S. Aiba, K. Sekiguchi, A. Kaneko, 2015, Evidence-based complementary and alternative medicine : eCAM.

Epithelial transient receptor potential ankyrin 1 (TRPA1)-dependent adrenomedullin upregulates blood flow in rat small intestine.

Masahiro Yamamoto, A. Kaneko, K. Ohbuchi, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Daikenchuto (TU-100) ameliorates colon microvascular dysfunction via endogenous adrenomedullin in Crohn’s disease rat model

Tsuyoshi Watanabe, A. Kaneko, Tatsuya Suzuki, 2011, Journal of Gastroenterology.

Transient receptor potential ankyrin 1 agonists improve intestinal transit in a murine model of postoperative ileus

Y. Uezono, A. Kaneko, K. Ohbuchi, 2016, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Preventive Effect of TU-100 on a Type-2 Model of Colitis in Mice: Possible Involvement of Enhancing Adrenomedullin in Intestinal Epithelial Cells

Masahiro Yamamoto, A. Kaneko, T. Kono, 2013, Gastroenterology research and practice.

Disease activity early in treatment as a predictor of future low disease activity in RA patients treated with iguratimod

H. Kanda, A. Kaneko, T. Kojima, 2016, Modern rheumatology.

Improved safety of biologic therapy for rheumatoid arthritis over the 8-year period since implementation in Japan: long-term results from a multicenter observational cohort study

A. Kaneko, M. Kojima, T. Kojima, 2016, Clinical Rheumatology.

Clinical results for tocilizumab over one year in the clinical setting as assessed by CDAI (clinical disease activity index): CRP at week 12 and MMP-3 at week 24 are predictive factors for CDAI

A. Kaneko, D. Kida, Tomotaro Sato, 2012, Rheumatology International.

Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex

K. Sekiguchi, Y. Kase, A. Kaneko, 2015, Evidence-based complementary and alternative medicine : eCAM.

Berberine is a dopamine D1- and D2-like receptor antagonist and ameliorates experimentally induced colitis by suppressing innate and adaptive immune responses

S. Matsushita, A. Kaneko, Masaaki Kawano, 2015, Journal of Neuroimmunology.

Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.

A. Nishi, Masahiro Yamamoto, Y. Iwasaki, 2021, Gene.

Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine

A. Nishi, Masahiro Yamamoto, Y. Iwasaki, 2020, bioRxiv.

herbal medicine 2 3 Running title : Recovery of alternative splicing from the senescence to healthy type by 4 an herbal medicine 5 6 7

A. Nishi, Masahiro Yamamoto, Y. Iwasaki, 2020 .

TU-100 (Daikenchuto) and Ginger Ameliorate Anti-CD3 Antibody Induced T Cell-Mediated Murine Enteritis: Microbe-Independent Effects Involving Akt and NF-κB Suppression

M. Bissonnette, E. Chang, Y. Kohgo, 2014, PloS one.

Increase of Akkermansia muciniphila by a Diet Containing Japanese Traditional Medicine Bofutsushosan in a Mouse Model of Non-Alcoholic Fatty Liver Disease

A. Nishi, Masahiro Yamamoto, Mitsue Nishiyama, 2020, Nutrients.

Multitargeted Effects of Hangeshashinto for Treatment of Chemotherapy-Induced Oral Mucositis on Inducible Prostaglandin E2 Production in Human Oral Keratinocytes

Y. Uezono, A. Kaneko, K. Ohbuchi, 2014, Integrative cancer therapies.

Monitoring C-reactive protein levels to predict favourable clinical outcomes from tocilizumab treatment in patients with rheumatoid arthritis

A. Kaneko, T. Kojima, N. Takahashi, 2013, Modern rheumatology.

Predictors for clinical effectiveness of baricitinib in rheumatoid arthritis patients in routine clinical practice: data from a Japanese multicenter registry

A. Kaneko, T. Kojima, N. Takahashi, 2020, Scientific Reports.

Disease Activity Score 28 (DAS28) using C-reactive protein underestimates disease activity and overestimates EULAR response criteria compared with DAS28 using erythrocyte sedimentation rate in a large observational cohort of rheumatoid arthritis patients in Japan

T. Matsui, A. Kaneko, S. Tohma, 2007, Annals of the rheumatic diseases.

Daikenchuto (TU‐100) alters murine hepatic and intestinal drug metabolizing enzymes in an in vivo dietary model: effects of gender and withdrawal

J. Miyoshi, E. Chang, Hyunyoung Jeong, 2017, Pharmacology research & perspectives.

Anti-colitis and -adhesion effects of daikenchuto via endogenous adrenomedullin enhancement in Crohn's disease mouse model.

Tsuyoshi Watanabe, A. Kaneko, Tatsuya Suzuki, 2010, Journal of Crohn's & colitis.

Hospital Anxiety and Depression Scale Score Is an Independent Factor Associated With the EuroQoL 5-Dimensional Descriptive System in Patients With Rheumatoid Arthritis

A. Kaneko, D. Kida, Y. Hattori, 2018, Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases.

Effects of Concomitant Methotrexate on Large Joint Replacement in Patients With Rheumatoid Arthritis Treated With Tumor Necrosis Factor Inhibitors: A Multicenter Retrospective Cohort Study in Japan

A. Kaneko, T. Kojima, N. Takahashi, 2015, Arthritis care & research.

Early aggressive intervention with tocilizumab for rheumatoid arthritis increases remission rate defined using a Boolean approach in clinical practice

A. Kaneko, T. Kojima, K. Funahashi, 2012, Modern rheumatology.

Immunosuppressive and Anti-Inflammatory Effects of Phenolic Nortriterpenoid, Demethylzeylasteral, from Tripterygium wilfordii

H. Maruyama, A. Kaneko, T. Morota, 1997 .

Ultrasound Assessment of Synovial Pathologic Features in Rheumatoid Arthritis Using Comprehensive Multiplane Images of the Second Metacarpophalangeal Joint: Identification of the Components That Are Reliable and Influential on the Global Assessment of the Whole Joint

Tamotsu Kamishima, T. Sumida, T. Koike, 2014, Arthritis & rheumatology.

Green Tea Extracts Prevent the Dioxin Toxicity through the Suppression of Transformation of the Aryl Hydrocarbon Receptor

H. Ashida, K. Kanazawa, A. Kaneko, 2003 .

Femoral Valgus Correction Angle for the Intramedullary Alignment Rod Is Strongly Associated with Femoral Lateral Bowing in Japanese Patients with Varus Knee Osteoarthritis Undergoing Total Knee Arthroplasty

A. Kaneko, N. Asai, Y. Hattori, 2022, Advances in orthopedics.

Evaluation of an operation support system using the femoral anterior tangent line to determine intraoperative femoral component rotation in total knee arthroplasty.

A. Kaneko, N. Asai, K. Ikuta, 2021, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

Prevalence of joint replacement surgery in rheumatoid arthritis patients: cross-sectional analysis in a large observational cohort in Japan

Sakae Tanaka, Y. Saeki, T. Matsui, 2009, Modern rheumatology.

Intestinal anastomosis surgery with no septic shock primes for a dysregulatory response to a second stimulus.

M. Aburada, Masahiro Yamamoto, Y. Kase, 2006, The Journal of surgical research.

Effects of actarit on synovial cell functions in patients with rheumatoid arthritis.

H. Nagafuchi, A. Kaneko, T. Asai, 1999, The Journal of rheumatology.

Clinical efficacy of abatacept compared to adalimumab and tocilizumab in rheumatoid arthritis patients with high disease activity

A. Kaneko, T. Kojima, N. Takahashi, 2013, Clinical Rheumatology.

Importance of methotrexate therapy concomitant with tocilizumab treatment in achieving better clinical outcomes for rheumatoid arthritis patients with high disease activity: an observational cohort study.

A. Kaneko, M. Kojima, T. Kojima, 2015, Rheumatology.

Daikenchuto (TU‐100) Suppresses Tumor Development in the Azoxymethane and APCmin/+ Mouse Models of Experimental Colon Cancer

M. Bissonnette, J. Miyoshi, E. Chang, 2017, Phytotherapy research : PTR.

Concomitant methotrexate has little effect on clinical outcomes of abatacept in rheumatoid arthritis: a propensity score matching analysis

A. Kaneko, T. Kojima, N. Takahashi, 2019, Clinical Rheumatology.

Comparison of composite disease activity indices for rheumatoid arthritis

T. Matsui, A. Kaneko, S. Tohma, 2011, Modern rheumatology.

Choice of and response to treatment in patients with early-diagnosed rheumatoid arthritis: Real-world data from an inception cohort in Japan (NICER-J).

H. Ishikawa, H. Wakabayashi, A. Kaneko, 2023, Journal of Orthopaedic Science.

Comparison of the effects of baricitinib and tocilizumab on disease activity in patients with rheumatoid arthritis: a propensity score matching analysis

A. Kaneko, T. Kojima, N. Takahashi, 2021, Clinical Rheumatology.

Comparison of efficacy and safety of tacrolimus and methotrexate in combination with abatacept in patients with rheumatoid arthritis; a retrospective observational study in the TBC Registry

A. Kaneko, T. Kojima, N. Takahashi, 2015, Modern rheumatology.

Survival after total joint arthroplasty in patients with rheumatoid arthritis. Comparison of the postoperative life expectancies and survival by initial operative years: 1970s and 1980s group versus 1990s group

A. Kaneko, Y. Eto, M. Tsukamoto, 2004, Modern rheumatology.

A review of tocilizumab treatment in 122 rheumatoid arthritis patients included in the Tsurumai Biologics Communication Registry (TBCR) Study

A. Kaneko, T. Kojima, N. Asai, 2013, Modern rheumatology.

FRI0098 The Safety and Treatment Efficacy of Abatacept in Rheumatoid Arthritis Patients with Interstitial Lung Disease: From the Tsurumai Biologics Communication Registry (TBCR) Multicenter Study

A. Kaneko, T. Kojima, N. Takahashi, 2015 .

Comparison of physical function in early rheumatoid arthritis patients treated with biologics for 1 year who achieved clinical remission or low disease activity

A. Kaneko, D. Kida, Y. Hattori, 2017, Clinical Rheumatology.

Multitargeted Effects of Hangeshashinto for Treatment of Chemotherapy-Induced Oral Mucositis on Inducible Prostaglandin E2 Production in Human Oral Keratinocytes

Y. Uezono, A. Kaneko, K. Ohbuchi, 2014, Integrative cancer therapies.

AB0478 Influences of Disease Activity at Initiation of Iguratimod, A Small-Molecule Antirheumatic Drug, on Efficacy of Iguratimod in Patients with Rheumatoid Arthritis: A Multicenter Study

H. Kanda, A. Kaneko, T. Kojima, 2014 .

Association between seropositivity and discontinuation of tumor necrosis factor inhibitors due to ineffectiveness in rheumatoid arthritis

A. Kaneko, T. Kojima, N. Takahashi, 2019, Clinical Rheumatology.

K. Nishida, A. Kaneko, I. Matsushita, 2013, Modern rheumatology.