J. Truglio

发表

Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors.

P. Tonge, C. Kisker, R. Slayden, 2017, Journal of the American Chemical Society.

Slow-onset inhibition of the FabI enoyl reductase from francisella tularensis: residence time and in vivo activity.

P. Tonge, C. Kisker, R. Slayden, 2009, ACS chemical biology.

Mechanism of the intramolecular Claisen condensation reaction catalyzed by MenB, a crotonase superfamily member.

M. García-Díaz, P. Tonge, C. Kisker, 2011, Biochemistry.

Prokaryotic nucleotide excision repair: the UvrABC system.

B. Van Houten, C. Kisker, D. Croteau, 2006, Chemical reviews.

Characterizing septum inhibition in Mycobacterium tuberculosis for novel drug discovery.

D. Raleigh, P. Tonge, C. Kisker, 2008, Tuberculosis.

A [32P]-NAD+-based method to identify and quantitate long residence time enoyl-ACP reductase inhibitors

Ch Lai, P. Tonge, Lauren A. Spagnuolo, 2015 .

Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus.

C. Kisker, K. Rajagopalan, S. Leimkühler, 2002, Structure.

Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family.

P. Tonge, C. Kisker, S. Kolappan, 2007, Biochemistry.

Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD

C. Kisker, B. V. Houten, D. Croteau, 2008, PLoS biology.

Mechanism of Substrate and Inhibitor Binding of Rhodobacter capsulatus Xanthine Dehydrogenase*

C. Kisker, S. Leimkühler, J. Truglio, 2009, Journal of Biological Chemistry.

Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K2 Biosynthesis*

Peter J Tonge, Karsten Theis, P. Tonge, 2003, Journal of Biological Chemistry.

Structure of the C‐terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute‐like catalytic triad

B. Van Houten, C. Kisker, Liqun Wang, 2007, The EMBO journal.

Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair

B. Van Houten, C. Kisker, D. Croteau, 2004, The EMBO journal.

Structural basis for DNA recognition and processing by UvrB

C. Kisker, Hong Wang, B. V. Houten, 2006, Nature Structural &Molecular Biology.

Identification of Residues within UvrB That Are Important for Efficient DNA Binding and Damage Processing*

B. Van Houten, C. Kisker, D. Croteau, 2004, Journal of Biological Chemistry.

Structural insights into the first incision reaction during nucleotide excision repair

B. Van Houten, C. Kisker, Liqun Wang, 2005, The EMBO journal.

Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module

H. Schindelin, Gang Zhao, Xiaoke Zhou, 2006, Proceedings of the National Academy of Sciences.

Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: Effect of the Y21 pKa on the Forward and Reverse Ground-State Reactions.

G. M. Greetham, I. Clark, M. Towrie, 2016, Journal of the American Chemical Society.

A [(32)P]NAD(+)-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors.

Ch Lai, P. Tonge, Lauren A. Spagnuolo, 2015, Analytical biochemistry.

High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis.

Peter J Tonge, Christopher F Stratton, P. Tonge, 2006, ACS chemical biology.

Mechanism of Substrate and Inhibitor Binding of Rhodobacter capsulatus Xanthine Dehydrogenase*

C. Kisker, S. Leimkühler, J. Truglio, 2009, Journal of Biological Chemistry.