M. Kelher

发表

Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation

E. Moore, C. Silliman, F. Sheppard, 2005, Journal of leukocyte biology.

A two‐event In vitro model of acute chest syndrome: The role of secretory phospholipase A2 and neutrophils

C. Silliman, R. Nuss, M. Kelher, 2011, Pediatric blood & cancer.

Tumor necrosis factor- (cid:1) causes release of cytosolic interleukin-18 from human neutrophils

C. Silliman, C. Dinarello, M. Kelher, 2010 .

Supernatants and lipids from stored red blood cells activate pulmonary microvascular endothelium through the BLT2 receptor and protein kinase C activation

C. Silliman, D. Elzi, A. Banerjee, 2017, Transfusion.

The acellular fraction of stored platelets promotes tumor cell invasion.

C. Roland, R. Brekken, C. Silliman, 2009, The Journal of surgical research.

ASSOCIATION FOR ACADEMIC SURGERY, 2008 The Acellular Fraction of Stored Platelets Promotes Tumor Cell Invasion

C. Roland, R. Brekken, C. Silliman, 2009 .

Red Blood Cell Transfusion

C. Silliman, M. Kelher, F. B. West, 2015, Trauma Induced Coagulopathy.

Risk factors, management and prevention of transfusion-related acute lung injury: a comprehensive update

C. Silliman, M. Kelher, S. Kuldanek, 2019, Expert review of hematology.

&agr;-Enolase Causes Proinflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils Through Plasmin Activation of Protease-Activated Receptor 2

E. Moore, C. Silliman, K. Hansen, 2015, Shock.

Platelet-Activating Factor-Mediated Endosome Formation Causes Membrane Translocation of p67phox and p40phox That Requires Recruitment and Activation of p38 MAPK, Rab5a, and Phosphatidylinositol 3-Kinase in Human Neutrophils1

E. Moore, C. Silliman, D. Elzi, 2008, The Journal of Immunology.

Gender-Specific Transfusion Affects Tumor-Associated Neutrophil: Macrophage Ratios in Murine Pancreatic Adenocarcinoma

C. Silliman, Xianzhong Meng, D. Fullerton, 2010, Journal of Gastrointestinal Surgery.

Effects of Blood Components and Whole Blood in a Model of Severe Trauma-Induced Coagulopathy.

E. Moore, C. Silliman, A. Banerjee, 2020, The Journal of surgical research.

Metabolomics of AS‐5 RBC supernatants following routine storage

E. Moore, A. D’Alessandro, C. Silliman, 2015, Vox sanguinis.

Fatty acid analysis of wild ruminant tissues: evolutionary implications for reducing diet-related chronic disease

Yong Li, M. Kelher, L. Cordain, 2002, European Journal of Clinical Nutrition.

Platelet-Activating Factor-Induced Clathrin-Mediated Endocytosis Requires β-Arrestin-1 Recruitment and Activation of the p38 MAPK Signalosome at the Plasma Membrane for Actin Bundle Formation1

E. Moore, C. Silliman, F. Sheppard, 2006, The Journal of Immunology.

Routine storage of red blood cell (RBC) units in additive solution‐3: a comprehensive investigation of the RBC metabolome

E. Moore, A. D’Alessandro, C. Silliman, 2015, Transfusion.

Complex expression pattern of the Barth syndrome gene product tafazzin in human cell lines and murine tissues.

T. M. Lewin, R. Coleman, G. Hatch, 2004, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength

C. Silliman, A. Banerjee, J. Di Paola, 2022, Platelets.

28‐day thawed plasma maintains α2‐antiplasmin levels and inhibits tPA‐induced fibrinolysis

E. Moore, C. Silliman, A. Banerjee, 2020, Vox sanguinis.

Leukotriene B4 and its Metabolites Prime the Neutrophil Oxidase and Induce Proinflammatory Activation of Human Pulmonary Microvascular Endothelial Cells

E. Moore, C. Silliman, D. Elzi, 2011, Shock.

LysoPCs induce Hck‐ and PKCδ‐mediated activation of PKCγ causing p47phox phosphorylation and membrane translocation in neutrophils

C. Silliman, D. Elzi, Xianzhong Meng, 2017, Journal of leukocyte biology.

Platelet-Activating Factor-Mediated Endosome Formation Causes Membrane Translocation of p67 and p40 That Requires Recruitment and Activation of p38 MAPK, Rab5a, and Phosphatidylinositol 3-Kinase in Human Neutrophils

C. Silliman, D. Elzi, A. Banerjee, 2008 .

C. Silliman, M. Kelher, R. Bercovitz, 2011 .

Lysophosphatidylcholines activate G2A inducing G(αi)₋₁-/G(αq/)₁₁- Ca²(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs.

C. Silliman, A. Banerjee, M. Kelher, 2010, The Biochemical journal.

Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium

A. Paterson, C. Silliman, D. Elzi, 2003, Journal of leukocyte biology.

A two-insult in vitro model of PMN-mediated pulmonary endothelial damage: requirements for adherence and chemokine release.

C. Smith, C. Silliman, D. Elzi, 2002, American journal of physiology. Cell physiology.

A comparison of different methods of red blood cell leukoreduction and additive solutions on the accumulation of neutrophil‐priming activity during storage

C. Silliman, K. Hansen, A. Banerjee, 2018, Transfusion.

Amantadine inhibits platelet-activating factor induced clathrin-mediated endocytosis in human neutrophils.

E. Moore, C. Silliman, L. Gries, 2009, American journal of physiology. Cell physiology.

Female Platelets Have Distinct Functional Activity Compared to Male Platelets: Implications in Transfusion Practice and Treatment of Trauma-Induced Coagulopathy.

A. Sauaia, E. Moore, M. Cohen, 2019, The journal of trauma and acute care surgery.

Plasma and lipids from stored platelets cause acute lung injury in an animal model

N. Voelkel, C. Silliman, M. Kelher, 2003, Transfusion.

The accumulation of lipids and proteins during red blood cell storage: the roles of leucoreduction and experimental filtration.

C. Silliman, M. Kelher, Timothy Burke, 2017, Blood transfusion = Trasfusione del sangue.

Antibodies to major histocompatibility complex class II antigens directly prime neutrophils and cause acute lung injury in a two‐event in vivo rat model

C. Silliman, A. Banerjee, M. Kelher, 2016, Transfusion.

microvascular endothelial cells in a two-event, in vitro model neutrophils and cause PMN-mediated damage to human pulmonary Donor antibodies to HNA-3a implicated in TRALI reactions prime

M. Kelher, P. Kopko, B. Curtis, 2013 .

Bioactive lipids from stored cellular blood components: in vitro method is crucial for proper interpretation

C. Silliman, M. Kelher, D. Ambruso, 2012, Transfusion.

The pro‐inflammatory effects of platelet contamination in plasma and mitigation strategies for avoidance

C. Silliman, M. Kelher, R. Bercovitz, 2012, Vox sanguinis.

Mirasol Pathogen Reduction Technology® treatment does not affect acute lung injury in a two‐event in vivo model caused by stored blood components

C. Silliman, M. Kelher, S. Marschner, 2010, Vox sanguinis.

Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model.

E. Moore, C. Silliman, Xianzhong Meng, 2009, Blood.

Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model.

C. Silliman, M. Kelher, D. Ambruso, 2007, Blood.

Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury.

C. Silliman, M. Kelher, N. McLaughlin, 2006, Blood.

The role of endothelial activation in the pathogenesis of transfusion‐related acute lung injury

C. Silliman, M. Kelher, 2005, Transfusion.

Hypotension and acute pulmonary insufficiency following transfusion of autologous red blood cells during surgery: a case report and review of the literature

C. Silliman, F. Kim, E. Moore, 2004, Transfusion medicine.

Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils.

A. Paterson, S. Anderson, C. Silliman, 2003, Cell calcium.

Systemic hyperfibrinolysis after trauma: a pilot study of targeted proteomic analysis of superposed mechanisms in patient plasma

James G. Chandler, A. Sauaia, E. Moore, 2018, The journal of trauma and acute care surgery.

Neutrophil function in children following allogeneic hematopoietic stem cell transplant

C. Silliman, M. Kelher, M. Kent, 2016, Pediatric transplantation.

Thrombin stimulates increased plasminogen activator inhibitor-1 release from liver compared to lung endothelium.

A. Sauaia, E. Moore, C. Silliman, 2018, The Journal of surgical research.

Thrombin Provokes Degranulation of Platelet &agr;-Granules Leading to the Release of Active Plasminogen Activator Inhibitor-1 (PAI-1)

A. Sauaia, E. Moore, C. Silliman, 2017, Shock.

Thrombin Stimulates Increased PAI-1 Release from Liver Compared to Lung Endothelium

A. Sauaia, C. Silliman, A. Banerjee, 2018 .

Experimental prestorage filtration removes antibodies and decreases lipids in RBC supernatants mitigating TRALI in vivo.

S. Sowemimo-Coker, C. Silliman, M. Kelher, 2014, Blood.

Hormones, age, and sex affect platelet responsiveness in vitro

M. Cohen, C. Silliman, A. Banerjee, 2022, Transfusion.

Oncogenic and Angiogenic Growth Factors Accumulate during Routine Storage of Apheresis Platelet Concentrates

C. Silliman, M. Kelher, J. Kanter, 2008, Clinical Cancer Research.

&agr;-Enolase Causes Proinflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils Through Plasmin Activation of Protease-Activated Receptor 2

E. Moore, C. Silliman, K. Hansen, 2015, Shock.

Proteomic Analysis of Human Mesenteric Lymph

E. Moore, C. Silliman, K. Hansen, 2011, Shock.

A pilot study of the metabolic profiles of apheresis platelets modified by donor age and sex and in vitro short‐term incubation with sex hormones

C. Silliman, K. Hansen, A. Banerjee, 2022, Transfusion.

The pro‐inflammatory potential of microparticles in red blood cell units

M. Kelher, F. B. West, M. Kent, 2014, Transfusion medicine.

Hypertonic saline inhibits arachidonic acid priming of the human neutrophil oxidase.

E. Moore, C. Silliman, A. Banerjee, 2012, The Journal of surgical research.

Identification of lipids that accumulate during the routine storage of prestorage leukoreduced red blood cells and cause acute lung injury

C. Silliman, D. Elzi, M. Kelher, 2011, Transfusion.

Antibodies to the HLA‐A2 antigen prime neutrophils and serve as the second event in an in vitro model of transfusion‐related acute lung injury

S. Sowemimo-Coker, C. Silliman, M. Kelher, 2014, Vox sanguinis.

The α-globin chain of hemoglobin potentiates tissue plasminogen activator induced hyperfibrinolysis in vitro

E. Moore, C. Silliman, K. Hansen, 2021, The journal of trauma and acute care surgery.

Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS

James G. Chandler, Kenneth L. Jones, A. Sauaia, 2020, Annals of surgery.

Physiological levels of interleukin‐18 stimulate multiple neutrophil functions through p38 MAP kinase activation

C. Silliman, C. Dinarello, M. Kelher, 2002, Journal of leukocyte biology.

Proteomic analysis of the supernatant of red blood cell units: the effects of storage and leucoreduction

E. Moore, C. Silliman, K. Hansen, 2013, Vox sanguinis.

PAS‐C platelets contain less plasma protein, lower anti‐A and anti‐B titers, and decreased HLA antibody specificities compared to plasma platelets

C. Silliman, S. Weisberg, B. Shaz, 2018, Transfusion.

Biological response modifiers in photochemically pathogen‐reduced versus untreated apheresis platelet concentrates

C. Silliman, M. Kelher, J. Kjeldsen-Kragh, 2013, Transfusion.

Proteomic analyses of human plasma: Venus versus Mars

C. Silliman, A. Banerjee, M. Dzieciatkowska, 2012, Transfusion.

Complement activation associated with transfusion related acute lung injury (TRALI)

C. Silliman, M. Kelher, P. Giclas, 2005 .

Kinase in Human Neutrophils MAPK , Rab 5 a , and Phosphatidylinositol Requires Recruitment and Activation of p 38 That phox and p 40 phox Translocation of p 67 Endosome Formation Causes Membrane Platelet-Activating Factor-Mediated

E. Moore, C. Silliman, D. Elzi, 2008 .

Proteomics of apheresis platelet supernatants during routine storage: Gender-related differences.

E. Moore, A. D’Alessandro, C. Silliman, 2015, Journal of proteomics.

Antibodies Specific for MHC Class II Antigens Cause TRALI Directly in a Two-Event in Vivo Model

C. Silliman, M. Kelher, 2012 .

A proposed clinical coagulation score for research in trauma-induced coagulopathy

A. Sauaia, C. Silliman, R. Lawless, 2023, The journal of trauma and acute care surgery.

Elucidating the molecular mechanisms of fibrinolytic shutdown after severe injury: The role of thrombin-activatable fibrinolysis inhibitor

James G. Chandler, Kenneth L. Jones, E. Moore, 2019, The journal of trauma and acute care surgery.

BLOOD TYPE O IS A RISK FACTOR FOR HYPERFIBRINOLYSIS AND MASSIVE TRANSFUSION AFTER SEVERE INJURY

A. Sauaia, C. Silliman, M. Kelher, 2022, Shock.

Platelet and cryoprecipitate transfusions from female donors improve coagulopathy in vitro

A. Sauaia, C. Silliman, M. Kelher, 2023, The journal of trauma and acute care surgery.

A Comparison of Different Methods of RBC Leukoreduction and Their Ability to Minimize Neutrophil Priming Activity during Storage

C. Silliman, M. Kelher, F. B. West, 2014 .

Elucidating the molecular mechanisms of fibrinolytic shutdown after severe injury: The role of thrombin-activatable fibrinolysis inhibitor

James G. Chandler, Kenneth L. Jones, E. Moore, 2023, The journal of trauma and acute care surgery.

Bradykinin release following trauma and hemorrhagic shock causes pulmonary alveolar leak in a rodent model

C. Silliman, A. Banerjee, M. Kelher, 2023, The journal of trauma and acute care surgery.

Thrombin Provokes PAI-1 Release from Platelets

E. Moore, C. Silliman, A. Banerjee, 2016 .

Routine storage of red blood cell (RBC) units in additive solution‐3: a comprehensive investigation of the RBC metabolome

E. Moore, A. D’Alessandro, C. Silliman, 2015, Transfusion.

Platelet Contamination in Plasma: a Possible Source of Biologic Mediators Linked to Transfusion-Related Acute Lung Injury.

C. Silliman, M. Kelher, Samina Y. Khan, 2009 .

Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model.

E. Moore, C. Silliman, Xianzhong Meng, 2009, Blood.

Red Blood Cell Transfusion

M. Kelher, F. B. West, Christopher C. Silliman, 2015, Trauma Induced Coagulopathy.

Tumor necrosis factor- (cid:1) causes release of cytosolic interleukin-18 from human neutrophils

M. Kelher, N. McLaughlin, Samina Y. Khan, 2010 .

RESUSCITATIVE ENDOVASCULAR BALLOON OCCLUSION OF THE AORTA: ZONE 1 REPERFUSION-INDUCED COAGULOPATHY

A. Sauaia, M. Kelher, Sanchayita Mitra, 2023, Shock.

A Two-Event In Vivo Model of Transfusion-Related Acute Lung Injury.

E. Moore, C. Silliman, S. Damle, 2006 .