Phillip D. Smith

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Isolation of Whole Mononuclear Cells from Peripheral Blood and Cord Blood

H. Zola, M. Kanof, Phillip D. Smith, 1996, Current protocols in immunology.

C. Morrow, Phillip D. Smith, Kyle M. Brawner, 2014, Cancer journal.

Emiko Mizoguchi, G. Meng, L. Miao, 2001, The Journal of Immunology.

Helicobacter pylori-Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice1

Ken B. Waites, P. Harris, K. Waites, 2000, The Journal of Immunology.

Complications of HIV/AIDS and other secondary immunodeficiencies

E. Janoff, Phillip D. Smith, 2015, Yamada's Textbook of Gastroenterology.

Glycosylation Patterns of HIV-1 gp120 Depend on the Type of Expressing Cells and Affect Antibody Recognition

J. Novak, S. Barnes, M. Raška, 2010, The Journal of Biological Chemistry.

Stromal regulation of human gastric dendritic cells restricts the Th1 response to Helicobacter pylori.

K. Waites, Phillip D. Smith, R. Stahl, 2011, Gastroenterology.

Cytokine gene profile in gastric mucosa in Helicobacter pylori infection and Zollinger-Ellison syndrome

R. Jensen, P. Harris, C. Wilcox, 2002, American Journal of Gastroenterology.

Cytokine gene profile in gastric mucosa in Helicobacter pylori infection and Zollinger-Ellison syndrome.

R. Jensen, P. Harris, C. Wilcox, 2002 .

Monocytes, Intestinal Macrophages, and for IgG Is Functionally Expressed in MHC Class I-Related Neonatal Fc Receptor

L. Miao, W. Lencer, R. Blumberg, 2013 .

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

Jihye Hwang, L. Harrington, I. Eltoum, 2022, bioRxiv.

Differential regulation of CD103 (αE integrin) expression in human dendritic cells by retinoic acid and Toll‐like receptor ligands

Mandi M. Roe, Phillip D. Smith, L. Smythies, 2017, Journal of leukocyte biology.

EpitheliumRectal Mucosa and Model Colonic HIV Type 1 Transcytosis through Human GP41-Specific Antibody Blocks Cell-Free

J. Kappes, M. Bomsel, Ernesto R. Drelichman, 2010 .

Gliadin Peptides Activate Blood Monocytes from Patients with Celiac Disease

M. Černá, Phillip D. Smith, L. Smythies, 2007, Journal of Clinical Immunology.

Endotoxin administration to humans primes alveolar macrophages for increased production of inflammatory mediators

J. Parrillo, S. Wahl, L. Wahl, 1994, Journal of Clinical Immunology.

74 – Immunologic disease of the gastrointestinal tract

C. Elson, Phillip D. Smith, 2008 .

Helicobacter pylori Infection Inhibits Phagocyte Clearance of Apoptotic Gastric Epithelial Cells

P. Mannon, P. Harris, C. Wilcox, 2013, The Journal of Immunology.

Helicobacter pylori-Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-g, Gene-Deficient Mice

K. Waites, Phillip D. Smith, J. Lindsey, 2000 .

Poliovirus replicons encoding the B subunit of Helicobacter pylori urease protect mice against H. pylori infection.

C. Morrow, K. Waites, Phillip D. Smith, 2005, Vaccine.

Cytomegalovirus Enhances Macrophage TLR Expression and MyD88-Mediated Signal Transduction To Potentiate Inducible Inflammatory Responses

W. Britt, M. Ballestas, L. Musgrove, 2014, The Journal of Immunology.

Isolation of Human Monocyte Populations

S. Wahl, L. Wahl, Phillip D. Smith, 2005, Current protocols in immunology.

Mucosal Correlates of Protection in HIV‐1‐Exposed Sero‐negative Persons

Phillip D. Smith, Ruizhong Shen, 2014, American journal of reproductive immunology.

Human cytomegalovirus enhances chemokine production by lipopolysaccharide-stimulated lamina propria macrophages.

W. Britt, C. Wilcox, Phillip D. Smith, 2002, The Journal of infectious diseases.

Inflammation Anergy in Human Intestinal Macrophages Is Due to Smad-induced IκBα Expression and NF-κB Inactivation

Michael D. George, D. Eckhoff, L. Novak, 2010, The Journal of Biological Chemistry.

Cytomegalovirus production by infected astrocytes correlates with transforming growth factor-beta release.

W. Britt, J. Orenstein, S. Wahl, 2003, The Journal of infectious diseases.

Cytomegalovirus blocks intestinal stroma‐induced down‐regulation of macrophage HIV‐1 infection

W. Britt, D. Eckhoff, A. Lazenby, 2006, Journal of leukocyte biology.

Gastrointestinal Infections in AIDS

H. Masur, T. Quinn, E. Janoff, 1992, Annals of Internal Medicine.

IgA-Mediated Activities and Consequently Are Down-Regulated for Intestinal Macrophages Lack CD 14 and CD 89

J. Orenstein, M. Russell, Phillip D. Smith, 2001 .

Elucidating the Role of the Interleukin-10 Receptor in Mucosal Inflammation Uncovers a Potential Treatment for Infantile Inflammatory Bowel Disease.

C. Elson, Phillip D. Smith, 2016, Gastroenterology.

Isolation of Whole Mononuclear Cells from Peripheral Blood and Cord Blood

H. Zola, M. Kanof, Phillip D. Smith, 1996, Current protocols in immunology.

Isolation of Monocyte/Macrophage Populations

L. Wahl, Phillip D. Smith, 1995 .

IgG antibody to Giardia lamblia detected by enzyme-linked immunosorbent assay

F. Gillin, T. Nash, Phillip D. Smith, 1981 .

Dendritic cells transmit HIV‐1 through human small intestinal mucosa

L. Novak, Phillip D. Smith, L. Smythies, 2010, Journal of leukocyte biology.

Human Gastric Epithelial Cells Contribute to Gastric Immune Regulation by Providing Retinoic Acid to Dendritic Cells

P. Mannon, K. Mönkemüller, P. Harris, 2014, Mucosal Immunology.

Biological parameters of HIV‐1 infection in primary intestinal lymphocytes and macrophages

G. Shaw, G. Meng, Phillip D. Smith, 2000, Journal of leukocyte biology.

Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infection

H. Richter, P. Clapham, L. Novak, 2009, Journal of Virology.

Emerging concepts in gastrointestinal aspects of HIV-1 pathogenesis and management

E. Janoff, Phillip D. Smith, 2001, Gastroenterology.

Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells

J. Kappes, G. Shaw, J. Orenstein, 2002, Nature Medicine.

GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium

J. Kappes, M. Bomsel, Ernesto R. Drelichman, 2010, The Journal of Immunology.

HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission

J. Novak, M. Raška, Phillip D. Smith, 2014, Journal of Virology.

Target Cells for HIV-1/SIV Infection in Mucosal Tissue

Phillip D. Smith, Ruizhong Shen, Phillip D. Smith and Ruizhong Shen, 2019, Current Immunology Reviews.

57 – Mucosal Immunopathophysiology of HIV Infection

Phillip D. Smith, 1994 .

Role of cytokines in infectious and noninfectious enteropathy in patients with AIDS

Phillip D. Smith, 1991, Immunologic research.

Helicobacter pylori gastritis in children is associated with a regulatory T-cell response.

R. Lorenz, A. Rollán, C. Serrano, 2008, Gastroenterology.

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity.

J. Orenstein, G. Meng, W. Benjamin, 2005, The Journal of clinical investigation.

Involvement o f Dendriti c Cells in the Pathogenesi s of Inflammator y Bowel Disease

F. León, Phillip D. Smith, L. Smythies, 2006 .

Involvement of dendritic cells in the pathogenesis of inflammatory bowel disease.

F. León, Phillip D. Smith, L. Smythies, 2006, Advances in experimental medicine and biology.

Chapter 26 – Antigen Handling and Presentation by Mucosal Dendritic Cells and Macrophages

F. León, Phillip D. Smith, L. Smythies, 2005 .

Cytomegalovirus Promotes Intestinal Macrophage-mediated Mucosal Inflammation through Induction of Smad7

W. Britt, M. Niederweis, M. Ballestas, 2018, Mucosal Immunology.

Interactions between H. pylori and the Gastric Microbiome: Impact on Gastric Homeostasis and Disease.

C. Serrano, P. Harris, Phillip D. Smith, 2021, Current opinion in physiology.

A phase I trial of recombinant human interferon-γ in patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome (AIDS)

R. Davey, A. Fauci, H. Masur, 1989, Journal of Clinical Immunology.

Macrophage Functions in HIV-1 Infection

J. Orenstein, S. Wahl, Phillip D. Smith, 1996 .

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

J. Novak, M. Hoelscher, L. Maboko, 2014, AIDS Research and Therapy.

Intestinal Macrophages Lack CD14 and CD89 and Consequently Are Down-Regulated for LPS- and IgA-Mediated Activities1

M. Russell, J. Orenstein, Phillip D. Smith, 2001, The Journal of Immunology.

Mucosal IL‐8 and TGF‐β recruit blood monocytes: evidence for cross‐talk between the lamina propria stroma and myeloid cells

D. Eckhoff, L. Novak, Phillip D. Smith, 2006, Journal of leukocyte biology.

Intestinal macrophages: unique effector cells of the innate immune system

C. Ochsenbauer-Jambor, Phillip D. Smith, L. Smythies, 2005, Immunological reviews.

Mucosal Macrophages in Defense and Regulation

T. Denning, Phillip D. Smith, L. Smythies, 2015 .

Helicobacter pylori Infection is Associated with an Altered Gastric Microbiota in Children

E. Lefkowitz, D. Zhi, C. Serrano, 2016, Mucosal Immunology.

Role of childhood infection in the sequelae of H. pylori disease

P. Harris, G. Perez-Perez, Phillip D. Smith, 2013, Gut microbes.

Characterization of Human Blood Monocytes and Intestinal Macrophages

Phillip D. Smith, L. Smythies, E. Dennis, 2017, Current protocols in immunology.

Principles of Mucosal Immunology

R. Blumberg, T. Macdonald, Phillip D. Smith, 2020 .

Human Immune Responses to Giardia lamblia

Phillip D. Smith, 1984 .

Macrophage HIV‐1 infection and the gastrointestinal tract reservoir

G. Shaw, J. Salazar-Gonzalez, G. Meng, 2003, Journal of leukocyte biology.

Interactions between HIV‐1 and Mucosal Cells in the Female Reproductive Tract

Phillip D. Smith, Ruizhong Shen, H. Richter, 2014, American journal of reproductive immunology.

Chronic proctitis in male homosexuals due to lymphogranuloma venereum

W. Brugge, J. Levine, Phillip D. Smith, 1980 .

Infection of gastrointestinal tract macrophages by HIV‐1

G. Shaw, G. Meng, Phillip D. Smith, 1997, Journal of leukocyte biology.

Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells

A. Berger, K. Ravichandran, Arup Sarkar, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

IMMUNOBIOLOGY OF MUCOSAL HIV-1 INFECTION

Phillip D. Smith, Ling Li, 1996 .

Mucosal immunology of the genital and gastrointestinal tracts and HIV-1 infection.

Z. Hel, J. Mestecky, Z. Moldoveanu, 2009, Journal of reproductive immunology.

Stromal Down-Regulation of Macrophage CD4/CCR5 Expression and NF-κB Activation Mediates HIV-1 Non-Permissiveness in Intestinal Macrophages

J. Kappes, G. Meng, P. Clapham, 2011, PLoS pathogens.

Early HIV‐1 Target Cells in Human Vaginal and Ectocervical Mucosa

H. Richter, Phillip D. Smith, Ruizhong Shen, 2011, American journal of reproductive immunology.

Vaginal Myeloid Dendritic Cells Transmit Founder HIV-1

J. Kappes, H. Richter, L. Novak, 2014, Journal of Virology.

Gene-Deficient Mice , g Exacerbated in IL-4, But Not IFN-Inflammation Is Th1 Mediated and -Induced Mucosal Helicobacter pylori

P. Harris, K. Waites, Phillip D. Smith, 2000 .

Chronic Rectal Bleeding due to Lymphogranuloma Venereum Proctocolitis

K. Waites, Phillip D. Smith, W. Geisler, 2012, The American Journal of Gastroenterology.

Mother-to-Child HIV-1 Transmission Events Are Differentially Impacted by Breast Milk and Its Components from HIV-1-Infected Women

M. Fowler, E. Janoff, J. Rahkola, 2015, PloS one.

Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover

S. Bellis, C. Serrano, M. Garrido, 2020, The Journal of Biological Chemistry.

CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion

Mandi M. Roe, Phillip D. Smith, L. Smythies, 2018, Front. Immunol..

Distribution of Microscopic Fields Lacking HIV-1 mRNA Positive Cells from Eight Patients with AIDS

C. Fox, H. Masur, Phillip D. Smith, 2003 .

Extracellular Matrix-associated Cytokines Regulate CD4+ Effector T-cell Responses in Human Intestinal Mucosa

Phillip D. Smith, L. Smythies, J. Cannon, 2010, Mucosal Immunology.

In vitro studies on bile acid deconjugation and lipolysis inhibition byGiardia lamblia

Phillip D. Smith, W. Brown, C. Horsburgh, 1981, Digestive Diseases and Sciences.

Inflammation Anergy in Human Intestinal Macrophages Is Due to Smad-induced IκBα Expression and NF-κB Inactivation*

Michael D. George, D. Eckhoff, L. Novak, 2010, The Journal of Biological Chemistry.

Intestinal macrophages and response to microbial encroachment

P. D. Smith, S. Wahl, Phillip D. Smith, 2011, Mucosal Immunology.

Inflammation Anergy in Human Intestinal Macrophages Is Due to Smad-induced IκBα Expression and NF-κB Inactivation

Michael D. George, D. Eckhoff, L. Novak, 2010, The Journal of Biological Chemistry.

Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS). Etiology and response to therapy.

A. Fauci, H. Masur, H. Lane, 1988, Annals of internal medicine.

Lamina propria lymphocytes, not macrophages, express CCR5 and CXCR4 and are the likely target cell for human immunodeficiency virus type 1 in the intestinal mucosa.

G. Shaw, P. D. Smith, G. Meng, 2000, The Journal of infectious diseases.

Intestinal macrophages display reduced permissiveness to human immunodeficiency virus 1 and decreased surface CCR5.

G. Shaw, P. D. Smith, G. Meng, 1999, Gastroenterology.

Severe Gastrointestinal Disease Due to HIV-1-Seronegative AIDS

K. Mönkemüller, L. Fry, S. Rickes, 2007, Zeitschrift fur Gastroenterologie.

Isolation and purification of CD14-negative mucosal macrophages from normal human small intestine.

J. Kearney, J. Orenstein, P. D. Smith, 1997, Journal of immunological methods.

High mucosal levels of tumor necrosis factor alpha messenger RNA in AIDS-associated cytomegalovirus-induced esophagitis.

H. Kiyono, P. D. Smith, P. Harris, 1998, Gastroenterology.

Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori–infected children

T. Cover, P. D. Smith, M. Salazar, 2013, Mucosal Immunology.

Role of childhood infection in the sequelae of H. pylori disease

P. Harris, G. Perez-Perez, Phillip D. Smith, 2013, Gut microbes.

Cytomegalovirus induction of tumor necrosis factor-alpha by human monocytes and mucosal macrophages.

M. Raffeld, P. D. Smith, S. Wahl, 1992, The Journal of clinical investigation.

Surface proteins from Helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosa

M. Blaser, P. D. Smith, S. Wahl, 1992, The Journal of experimental medicine.

Stromal regulation of human gastric dendritic cells restricts the Th1 response to Helicobacter pylori.

K. Waites, Phillip D. Smith, R. Stahl, 2011, Gastroenterology.

Candida albicans in patients with the acquired immunodeficiency syndrome: absence of a novel of hypervirulent strain.

P. D. Smith, S. Wahl, K. Kwon-Chung, 1990, The Journal of infectious diseases.

Intestinal macrophages in defense of the mucosa

Phillip D. Smith, L. Smythies, 2020 .

Eradication of Helicobacter pylori in Children Restores the Structure of the Gastric Bacterial Community to That of Non-infected Children.

C. Serrano, P. Harris, C. Morrow, 2019, Gastroenterology.

Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa

C H Fox, D. Alling, C. Fox, 1994, The Journal of experimental medicine.

Vitamin B12 malabsorption in patients with acquired immunodeficiency syndrome.

M. Horne, C. Fox, A. Fauci, 1989, Archives of internal medicine.

Novel Biomarkers and Distinct Transcriptomic Profile of Barrett’s Esophagus Epithelial Stem Cells

D. Crossman, S. Peter, Phillip D. Smith, 2023, bioRxiv.

Helicobacter pylori gastritis in children is associated with a regulatory T-cell response.

R. Lorenz, C. Serrano, P. Harris, 2008, Gastroenterology.

Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine production.

M. Blaser, P. D. Smith, H. Mobley, 1996, Gastroenterology.

Isolation of Human Monocyte Populations

S. Wahl, L. Wahl, Phillip D. Smith, 2005, Current protocols in immunology.

Perspectives on gastrointestinal infections in AIDS.

P. D. Smith, E. Janoff, Phillip D. Smith, 1988, Gastroenterology clinics of North America.

Adenovirus colitis in the acquired immunodeficiency syndrome.

J. Orenstein, P. D. Smith, J. Manischewitz, 1991, Gastroenterology.