D. Demon

发表

Proteome-wide Substrate Analysis Indicates Substrate Exclusion as a Mechanism to Generate Caspase-7 Versus Caspase-3 Specificity*

J. Verspurten, P. Vandenabeele, F. Rousseau, 2009, Molecular & Cellular Proteomics.

Protective and detrimental roles of inflammasomes in disease

M. Lamkanfi, D. Demon, H. Van Gorp, 2015, Seminars in Immunopathology.

Does caspase-12 suppress inflammasome activation?

M. Lamkanfi, F. Van Hauwermeiren, L. Vande Walle, 2016, Nature.

Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock.

T. Vanden Berghe, P. Vandenabeele, N. Takahashi, 2014, American journal of respiratory and critical care medicine.

Sensing the enemy within: how macrophages detect intracellular Gram-negative bacteria

M. Lamkanfi, L. Vande Walle, D. Demon, 2014, Trends in biochemical sciences.

Non-Classical ProIL-1beta Activation during Mammary Gland Infection Is Pathogen-Dependent but Caspase-1 Independent

P. Vandenabeele, H. Carlsen, N. Sanders, 2014, PloS one.

Staphylococcus aureus seroproteomes discriminate ruminant isolates causing mild or severe mastitis

David Hernández, P. François, J. Schrenzel, 2011, Veterinary research.

Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

E. De Baere, M. Lamkanfi, D. Bogaert, 2016, Proceedings of the National Academy of Sciences.

Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens*

M. Lamkanfi, P. Vogel, T. Kanneganti, 2012, The Journal of Biological Chemistry.

Complementarity and redundancy of IL-22-producing innate lymphoid cells

W. Shi, G. Smyth, J. Renauld, 2015, Nature Immunology.

Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4

M. Lamkanfi, T. Kanneganti, M. Matusiak, 2017, Cell reports.

Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine.

D. Demon, S. Daminet, E. Meyer, 2010, Veterinary immunology and immunopathology.

Escherichia coli induces bovine neutrophil cell death independent from caspase-3/-7/-1, but with phosphatidylserine exposure prior to membrane rupture.

P. Vandenabeele, F. Boyen, C. Guérin, 2013, Veterinary immunology and immunopathology.

GSDMD drives canonical inflammasome‐induced neutrophil pyroptosis and is dispensable for NETosis

M. Lamkanfi, A. Wullaert, Dhruv Chauhan, 2022, EMBO reports.

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

J. Konvalinka, M. Lamkanfi, Victoria C. Pham, 2019, PLoS biology.

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

J. Konvalinka, M. Lamkanfi, Victoria C. Pham, 2019, bioRxiv.

An inactivating caspase-11 passenger mutation muddles sepsis research.

T. Vanden Berghe, P. Vandenabeele, T. Mak, 2013, American journal of respiratory and critical care medicine.

Short communication: Antimicrobial efficacy of intramammary treatment with a novel biphenomycin compound against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli-induced mouse mastitis.

K. Breyne, D. Demon, E. Meyer, 2013, Journal of dairy science.

Inflammatory mediators in Escherichia coli-induced mastitis in mice.

T. Vanden Berghe, P. Vandenabeele, D. Demon, 2008, Comparative immunology, microbiology and infectious diseases.

The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice.

K. Breyne, D. Demon, E. Meyer, 2012, Veterinary microbiology.

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

W. Meutermans, A. Lloyd, T. Cheng, 2015, Nature Communications.

Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections

J. Sirard, B. Ryffel, J. Veening, 2017, Mucosal Immunology.

Escherichia coli α-Hemolysin Counteracts the Anti-Virulence Innate Immune Response Triggered by the Rho GTPase Activating Toxin CNF1 during Bacteremia

J. Mege, L. Landraud, P. Auberger, 2015, PLoS pathogens.

Severity of sepsis-induced acute kidney injury in a novel mouse model is age dependent*

R. Vanholder, K. Chiers, D. Demon, 2012, Critical care medicine.

Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulphate-induced colitis

M. Lamkanfi, T. Kanneganti, A. Kuchmiy, 2014, Mucosal Immunology.

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes

S. Janssens, V. Timmerman, M. Lamkanfi, 2015, Journal of Neuroinflammation.

Caspase substrates: easily caught in deep waters?

Kris Gevaert, Petra Van Damme, Wim Declercq, 2009, Trends in biotechnology.

Chitinase-like Proteins are Candidate Biomarkers for Sepsis-induced Acute Kidney Injury*

R Vanholder, R. Vanholder, K. Gevaert, 2012, Molecular & Cellular Proteomics.

Complementarity and redundancy of IL-22-producing innate lymphoid cells

W. Shi, G. Smyth, J. Renauld, 2015, Nature Immunology.

Protective and detrimental roles of inflammasomes in disease

M. Lamkanfi, D. Demon, Pedro H. V. Saavedra, 2015, Seminars in Immunopathology.

Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis

M. Lamkanfi, A. Kuchmiy, D. Demon, 2014, Mucosal Immunology.

Does caspase-12 suppress inflammasome activation?

M. Lamkanfi, F. Van Hauwermeiren, D. Demon, 2016, Nature.

Caspase substrates: easily caught in deep waters?

T. Vanden Berghe, P. Vandenabeele, K. Gevaert, 2009, Trends in biotechnology.

The autoinflammation-associated NLRC4V341A mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice

G. van Loo, M. Lamkanfi, D. Demon, 2023, Frontiers in immunology.