S. James

发表

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

P. Cohen, D. Alessi, C. Downes, 1997, Current Biology.

Structural and mechanistic features of phospholipases C: effectors of inositol phospholipid-mediated signal transduction.

C. Downes, S. James, 1997, Cellular signalling.

A G-protein beta gamma-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol.

P. Casey, C. Downes, P. Thomason, 1994, The Journal of biological chemistry.

A model of activation of the protein tyrosine phosphatase SHP-2 by the human leptin receptor.

S. James, A. Löthgren, M. Mccartney, 2001, Biochimica et biophysica acta.

Kinetic analysis of phospholipase C beta isoforms using phospholipid-detergent mixed micelles. Evidence for interfacial catalysis involving distinct micelle binding and catalytic steps.

T. K. Harden, A. Paterson, C. Downes, 1995, The Journal of biological chemistry.

Oxazolones as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

Meredith Williams, S. James, C. Kaiser, 2007, Bioorganic & medicinal chemistry letters.

Interfacial hydrolysis of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate by turkey erythrocyte phospholipase C.

C. Downes, R. Demel, S. James, 1994, The Biochemical journal.

Association of a phosphatidylinositol-specific 3-kinase with a human trans-Golgi network resident protein

C. Downes, S. James, J. Lucocq, 1997, Current Biology.

Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B).

J. Weigelt, J. Schultz, K. Benkestock, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and biological activity of a novel class of pyridazine analogues as non-competitive reversible inhibitors of protein tyrosine phosphatase 1B (PTP1B).

Meredith Williams, S. James, E. Barker, 2002, Bioorganic & medicinal chemistry.

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation.

D. Alessi, C. Downes, A. Holmes, 1996, The Biochemical journal.

Identification of a highly effective asymmetric phase-transfer catalyst derived from α-methylnaphthylamine

S. James, B. Lygo, Bryan Allbutt, 2003 .

Photo-oxidation of crystalline chymotrypsin in the presence of methylene blue.

S. James, L. Weil, A. Buchert, 1953, Archives of biochemistry and biophysics.

Dependence of the activity of phospholipase C beta on surface pressure and surface composition in phospholipid monolayers and its implications for their regulation.

A. Paterson, C. Downes, R. Demel, 1997, Biochemistry.

Kinetic Analysis of Phospholipase C Isoforms Using Phospholipid-Detergent Mixed Micelles

A. Paterson, C. Downes, S. James, 1995, The Journal of Biological Chemistry.

Catalytic Domain of Phosphoinositide-specific Phospholipase C (PLC)

Roger L. Williams, C. Downes, O. Perisic, 1998, The Journal of Biological Chemistry.