M. Melville

发表

Predicting cell-specific productivity from CHO gene expression.

C. Clarke, P. Meleady, N. Barron, 2011, Journal of biotechnology.

Microarray and proteomics expression profiling identifies several candidates, including the valosin‐containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines

Mark Leonard, Niall Barron, Martin Clynes, 2010, Biotechnology and bioengineering.

Sustained productivity in recombinant Chinese Hamster Ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype

Mark Leonard, Niall Barron, Martin Clynes, 2011, BMC biotechnology.

P58IPK, a novel cochaperone containing tetratricopeptide repeats and a J-domain with oncogenic potential

M. Katze, M. Melville, S-L. Tan, 2000, Cellular and Molecular Life Sciences CMLS.

Proteomic profiling of CHO cells with enhanced rhBMP‐2 productivity following co‐expression of PACEsol

M. Henry, P. Meleady, M. Clynes, 2008, Proteomics.

The Direct Binding of the Catalytic Subunit of Protein Phosphatase 1 to the PKR Protein Kinase Is Necessary but Not Sufficient for Inactivation and Disruption of Enzyme Dimer Formation*

M. Katze, Seng-Lai Tan, C. Blakely, 2002, The Journal of Biological Chemistry.

The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR.

M. Katze, B. Freeman, W. Welch, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of Interferon-Induced Protein Kinase PKR: Modulation of P58IPK Inhibitory Function by a Novel Protein, P52rIPK

M. Katze, P. Romano, M. Gale, 1998, Molecular and Cellular Biology.

Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT.

J. Frydman, M. Melville, A. Dunn, 2001, Journal of structural biology.

The Hsp70 and TRiC/CCT Chaperone Systems Cooperate In Vivo To Assemble the Von Hippel-Lindau Tumor Suppressor Complex

J. Frydman, A. J. McClellan, M. Melville, 2003, Molecular and Cellular Biology.

Development and characterization of a Chinese hamster ovary cell-specific oligonucleotide microarray

N. Barron, M. Clynes, P. Doolan, 2011, Biotechnology Letters.

Transcriptional Profiling of Gene Expression Changes in a PACE-Transfected CHO DUKX Cell Line Secreting High Levels of rhBMP-2

P. Meleady, M. Clynes, P. Doolan, 2008, Molecular biotechnology.

Microarray expression profiling identifies genes regulating sustained cell specific productivity (S‐Qp) in CHO K1 production cell lines

Finbarr O'Sullivan, Mark Leonard, Niall Barron, 2012, Biotechnology journal.

The Cellular Inhibitor of the PKR Protein Kinase, P58IPK, Is an Influenza Virus-activated Co-chaperone That Modulates Heat Shock Protein 70 Activity*

M. Katze, Seng-Lai Tan, R. Morimoto, 1999, The Journal of Biological Chemistry.

Mammalian cell line developments in speed and efficiency.

Scott Estes, S. Estes, M. Melville, 2014, Advances in biochemical engineering/biotechnology.

Domain Requirements of DnaJ-like (Hsp40) Molecular Chaperones in the Activation of a Steroid Hormone Receptor*

M. Cheetham, M. Melville, A. Caplan, 1999, The Journal of Biological Chemistry.

Large scale microarray profiling and coexpression network analysis of CHO cells identifies transcriptional modules associated with growth and productivity.

C. Clarke, P. Meleady, N. Barron, 2011, Journal of biotechnology.